• 한국가시화정보학회:학술대회논문집
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• 2004.04a
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• pp.19-28
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• 2004

유동장의 특성을 구분할 수 있는 척도는 평균자유행로와 특성거리의 비인 누센수이다. 누센수에 따라서 유장은 연속체영역, 미끄럼영역, 천이영역, 및 자유분자영역으로 나누어진다. 고고도에서 비행체 주위의 유동장, 진공에서의 유동장 등이 비연속체영역 즉 저밀도유동장에 해당된다. 비연속체영역에 해당되는 또 다른 중요한 분야는 미세 유동장이다. 최근에 관심이 대두되고 있는 미세항공기(MAV)와 실리콘혁명 이래 유망한 미래기술중의 하나인 MEMS 장치 주위의 유동장 등이 바로 미세 유동장이다. 비연속체영역에서 유체의 이동 및 전달현상을 기술하기 위하여는 Boltzmann 방정식을 해석하여야한다. Navier-Stokes 방정식을 이용한 기존의 CFD 기법이 적용되지 않는 새로운 유동영역이기 때문이다. 본 발표에서는 Boltzmann 방정식의 유력한 해법인 직접모사(Direct Simulation Monte Carlo)법을 이용한 저밀도 유동장 해석이 소개될 것이다. 또한 직접모사법이 이용되기 어려운 다양한 저속 유동장에 대한 해석결과도 소개될 것이다.

• Journal of Life Science
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• v.25 no.8
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• pp.849-860
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• 2015

The anti-cancer activities of Rhus verniciflua Stokes (GC), Ulmus davidiana var. japonica Nakai (UGP) and arsenium sublimatum (SS) extracts, which have been used Oriental medicine therapy for various diseases, were investigated. The treatment of GC, UGP and SS alone, and combined treatment with GC, UGP and SS did not affect the cell viability in the mouse normal cell lines (RAW 264.7 macrophages and C2C12 myoblasts). However, co-treatment with GC, UGP and SS markedly induces apoptosis in human gastric cancer AGS cells, but not in other various cancer cell lines (human lung cancer A549, colon cancer HCT116, liver cancer Hep3B and bladder T24 cells) as evidenced by formation of apoptotic bodies, chromatin condensation, and accumulation of annexin-V positive cells. Co-treatment with GC, UGP and SS effectively induced the expression levels of Fas and Fas ligand, and inhibited the levels IAP family proteins such as XIAP, cIAP-1 and survivin, and anti-apoptotic Bcl-xL proteins compared with treatment with either agent alone. Combined treatment also significantly induced the loss of mitochondrial membrane potential, which was associated with the activation of caspases (-3, -8, and -9) and degradation of poly (ADP-ribose) polymerase. However, the cytotoxic effects induced by co-treatment with GC, UGP and SS were significantly attenuated by pan-caspases inhibitor, z-VAD-fmk, indicating an important role for caspases. These results indicated that the caspases were key regulators of apoptosis in response to co-treatment of GC, UGP and SS in human gastric cancer AGS cells and further studies will be needed to identify the active compounds.

• Fire Science and Engineering
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• v.29 no.5
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• pp.42-50
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• 2015

Three simulation approaches for turbulence were applied for the computation of propane dispersion in a simplified real-scale urban area with one building:, Large Eddy Simulation (LES), Detached Eddy Simulation (DES), and Unsteady Reynolds Averaged Navier-Stokes (RANS). The computations were performed using FLUENT 14, and the grid system was made with ICEM-CFD. The propane distribution depended on the prediction performance of the three simulation approaches for the eddy structure around the building. LES and DES showed relatively similar results for the eddy structure and propane distribution, while the RANS prediction of the propane distribution was unrealistic. RANS was found to be inappropriate for computation of the gas dispersion process due to poor prediction performance for the unsteady turbulence. Considering the computational results and cost, DES is believed to be the optimal choice for computation of the gas dispersion in a real-scale space.

• The Journal of Internal Korean Medicine
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• v.32 no.1
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• pp.129-135
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• 2011

This report documents a case in which the administration of an herbal product, an extract of the lacquer tree, Rhus verniciflua Stokes, as sequential and concurrent treatment with chemotherapy was associated with a long term survival and good quality of life in a patient with metastatic non-small cell lung cancer(NSCLC). A 51-year-old Korean female was referred to the $M{\cdot}{\mu}$ Integrative Cancer Center, East-West Neo Medical centrer, Kyung Hee University for stage IV, metastatic NSCLC. She was treated with aRVS alone for 19 months and then received 1st line paclitaxel/carboplatin combined with aRVS, 2nd line gefitinib, and 3rd line pemetrexed. The number of cycles of pemetrexed administered was seventeen. aRVS was restarted as the 13th pemetrexed was administered. Pemetrexed with aRVS is currently ongoing. This patient has been alive for 41 months, and has been keeping a good performance status so far. We suggest aRVS as sequential and concurrent treatment with chemotherapy is an effective alternative treatment strategy.

• Journal of the Korean Society for Nondestructive Testing
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• v.36 no.6
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• pp.443-450
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• 2016

In this study, we propose a novel fiber optic sensor to show the measurement feasibility of distributed temperature and strains in a single sensing fiber line. Distributed temperature can be measured using optical time domain reflectometry (OTDR) with a Raman anti-Stokes light in the sensing fiber line. Moreover, the strain can be measured by fiber Bragg gratings (FBGs) in the same sensing fiber line. The anti-Stokes Raman back-scattering lights from both ends of the sensing fiber, which consists of a 4 km single mode optical fiber, are acquired and inserted into a newly formulated equation to calculate the temperature. Furthermore, the center wavelengths from the FBGs in the sensing fiber are detected by an optical spectrum analyzer; these are converted to strain values. The initial wavelengths of the FBGs are selected to avoid a cross-talk with the wavelength of the Raman pulsed pump light. Wavelength shifts from a tension test were found to be 0.1 nm, 0.17 nm, 0.29 nm, and 0.00 nm, with corresponding strain values of $85.76{\mu}{\epsilon}$, $145.55{\mu}{\epsilon}$, $247.86{\mu}{\epsilon}$, and $0.00{\mu}{\epsilon}$, respectively. In addition, a 50 m portion of the sensing fiber from $30^{\circ}C$ to $70^{\circ}C$ at $10^{\circ}C$ intervals was used to measure the distributed temperature. In all tests, the temperature measurement accuracy of the proposed sensor was less than $0.50^{\circ}C$.

• The KIPS Transactions:PartA
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• v.14A no.4
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• pp.191-196
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• 2007

In the field of computer graphics, Navier-Stokes equations would be used for realistic simulations of smokes and currents. However, implementations derived from these equations are hard to achieve for real-time simulations, mainly due to its massive and complex calculations. Thus, there have been various attempts to approximate these equations for real-time simulation of smokes and others. When the advection terms of the equations are approximated by the Semi-Lagrange methods, the fluid density can be rapidly reduced and small-scale vorticity phenomena are easy to be missed, mainly due to the numerical losses over time. In this paper, we propose an improved numerical method to approximately calculate the advection terms, and thus eliminate these problems. To calculate the advection terms, our method starts to set critical regions around the target grid points. Then, among the grid points in a specific critical region, we search for a grid point which will be advected to the target grid point, and use the velocity of this grid point as its advection vector. This method would reduce the numerical losses in the calculation of densities and vorticity phenomena, and finally can implement more realistic smoke simulations. We also improve the overall efficiency of vector calculations and related operations through GPU-based implementation techniques, and thus finally achieve the real-time simulation.

• Journal of Korean Society of Coastal and Ocean Engineers
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• v.32 no.1
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• pp.69-84
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• 2020

Natural shoreline repeats its re-treatment and advance in response to the endlessly varying sea-conditions, and once severely eroded under stormy weather conditions, natural beaches are gradually recovered via a boundary layer streaming when swells are prevailing after storms cease. Our understanding of the boundary layer streaming over surf-zone often falls short despite its great engineering value, and here it should be noted that the most sediments available along the shore are supplied over the surf-zone. In this rationale, numerical simulation was implemented to investigate the hydraulic characteristics of boundary layer streaming over the surf zone in this study. In doing so, comprehensive numerical models made of Spatially filtered Navier-Stokes Eq., LES (Large Eddy Simulation), Dynamic Smagorinsky turbulence closure were used, and the effects of turbulence closure such as Dynamic Smagorinsky in LES and k-ε on the numerically simulated flow field were also investigated. Numerical results show that due to the intrinsic limits of k-ε turbulence model, numerically simulated flow velocity near the bottom based on k-ε model and wall function are over-predicted than the one using Dynamic Smagorinsky in LES. It is also shown that flow velocities near the bottom are faster than the one above the bottom which are relatively free from the presence of the bottom, complying the typical boundary layer streaming by Longuet-Higgins (1957), the spatial scope where boundary layer streaming are occurring is extended well into the surf zone as incoming waves are getting longer. These tendencies are plausible considering that it is the bottom friction that triggers a boundary layer streaming, and longer waves start to feel the bottom much faster than shorter waves.

• Journal of Energy Engineering
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• v.4 no.3
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• pp.331-337
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• 1995

석탄가스화 복합발전 시스템은 고효율 및 우수한 환경보전성으로 인하여 차세대 화력발전 시스템으로 각광받고 있다. 본 연구는 석탄가스화기내의 비반응 유동장에 대한 연구로서, 순수유동장 및 미분탄입자를 포함한 이상유동장에 대한 전산해석을 수행하였다. 가스화기내의 유동장을 기술하는 Navier-Stokes방정식을 유한차분법에 의하여 해석하고 그 결과를 나타내었다. 특히 선회유동의 영향에 의한 미분탄입자의 거동 및 재순환영역의 특성에 대하여 선회강도의 함수로 고찰하였다. 해석결과에 의하면 가스화기내에서는 며책의 재순환영역이 형성됨을 알 수 있었다. 비반응유동장의 해석결과이지만, 선회유동은 화염안정화에 긍정적인 영향을 줄 수 있을 것으로 추측되는 결과를 보였다.

• Proceedings of the Korean Institute of Navigation and Port Research Conference
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• 2016.05a
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• pp.88-89
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• 2016

선택적 환원 촉매(SCR : Selective Catalytic Reduction) 시스템은 대기오염을 예방하기 위한 배기가스 처리장치 중 하나이다. 본 연구에서는 전산유체역학(CFD : Computational Fluid Dynamics)를 사용하여 SCR 시스템 의 효율향상을 위하여 ANSYS-CFX package를 이용하여 점성 유동 해석을 수행하였다. SCR 시스템의 점성 유동 흐름의 전산 유체 역학을 이용하여 시뮬레이션하기 위하여 Navier-Stokes 방정식을 지배방정식으로 사용하였다. CATIA V5를 사용하여 SCR 시스템의 형상을 3D 모델링을 하였고, 암모니아와 배기가스의 혼합 비율을 확인하기 위해 요소수 분사 노즐의 위치를 변경하였다. 요소수 분사 노즐은 배기관의 입구로부터 1/3, 1/2, 2/3에 위치한다. 또한, 분사 노즐의 위치가 배기관 입구의 1/3에 위치할 때 노즐의 분사구수에 따른 효율을 확인하기 위하여 분사구수를 4Hole, 6Hole, 8Hole일 경우를 확인하여 비교하였다. 시뮬레이션의 결과로는 배기관 입구에 가까울수록, 분사구수가 많을수록 효율이 좋아짐을 확인하였다.

• Journal of computational fluids engineering
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• v.3 no.1
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• pp.54-62
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• 1998

본 논문은 2차원 해면효과의 수치계산 결과를 정리하였다. 지면으로부터의 높이변화에 따른 점성유동장을 계산하기 위하여 지배방정식으로는 비압축성 RANS 방정식을, 시간에 대하여서는 음해법으로 프로그램을 구성하였다. 압력항은 가상압축성과 4차 수치확산항을 추가하는 것에 의해 계산하였으며, 높은 레이놀즈 수에서의 효과적인 계산을 위해 Baldwin- Lomax 난류모델을 도입하였다. 해면효과가 없는 무한유중에서의 NACA-0012 단면 계산결과를 실험 데이터와 비교하는 것에 의해 프로그램의 타당성을 확인하였다. NACA-6409와 두께 비 4.6%의 날개에 대하여 해면효과를 고려한 계산을 수행하였다. 계산결과, 높이의 변화에 따라 계산된 무차원계수, 압력 및 속도분포는 해면효과의 특성을 잘 보여주고 있다.