• Journal of the Korea Academia-Industrial cooperation Society
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• 제15권11호
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• pp.6446-6451
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• 2014

Pneumatic motors are quite attractive for many applications because of their competitive price, light-weight, easy assembly, safety in hazardous areas as well as other features, such as a good force/weight ratio and operation in exceptionally harsh environments. In contrast to these advantages, pneumatic motors have limited use in applications, particularly those requiring a fast and precise response. These undesirable characteristics are due to the high compressibility of air and from the nonlinearities in pneumatic systems. This paper presents the sliding mode controller based on 3-loop(SMCB3L), which increases the load stiffness to control the rotation angle of a pneumatic motor. The characteristics for the step responses and load disturbances of the proposed controller were compared with the conventional PID controller. The experimental results showed that a properly designed SMCB3L is capable of high positioning accuracy within ${\pm}0.05mm$. Furthermore, the load stiffness of the SMCB3L can be improved 3.5 fold compared to that of PID controllers.

• Microbiology and Biotechnology Letters
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• 제27권4호
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• pp.311-319
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• 1999

Leaves of Aloe vera Linne and bloods of domestic animal were composted in a soild state fermentation reactor (SSFR) by using microbial additive including a bulking and moisture controlling agent. From solid-culture of microbial additive, 10 species of bacteria and 10 species of fungi were isolated and, their enzyme activities including amylase, carboxy methyl cellulase CMCase, lipase and protease were detected. Optimum fermentation conditions of Aloe leaves and domestic animal bloods in SSFR were obtained from the studies of response surface analysis employing microbial additive content, initial moisture content, and fermentation temperature as the independent variables. The optimum conditions for SSFR using Aloe leaves were obtained at 9.45$\pm$73%(w/w) of microbial additives, 62.73$\pm$4.54%(w/w) of initial moisture content and 55.32$\pm$3.14$^{\circ}C$ of fermentation temperature while those for SSFR using domestic animal bloods were obtained at 10.25$\pm$2.04%, 58.68$\pm$4.97% and 57.85$\pm$5.$65^{\circ}C$, respectively. Composting process in SSFR was initially proceeded through fermentation and solid materials were decomposed within 24 hours by maintaining higher moisture level, and maturing and drying steps are followed later. After the fermentation step, the concentrations of solid phase inorganic components were increased while that of organic components were decreased. Also, concentrations of total organic carbon(TOC), peptides, amino acids, polysaccharides, and low fatty acids in water extracts were increased. As fermentation in composting process depends on initial C/N ratios in water extracts of two samples were increased because of increased water-soluble TOC. From these results, it was revealed that solid state fermentation reactor using microbial additives can be used in composting process of organic wastes with broad C/N ratio.

• Journal of Microbiology and Biotechnology
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• 제24권10호
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• pp.1427-1437
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• 2014

Enzymatic hydrolysis of lignocellulosic biomass into fermentable sugars is a key step in the conversion of agricultural by-products to biofuels and value-added chemicals. Utilization of a robust microorganism for on-site production of biomass-degrading enzymes has gained increasing interest as an economical approach for supplying enzymes to biorefinery processes. In this study, production of multi-polysaccharide-degrading enzymes from Aspergillus aculeatus BCC199 by solid-state fermentation was improved through the statistical design approach. Among the operational parameters, yeast extract and soybean meal as well as the nonionic surfactant Tween 20 and initial pH were found as key parameters for maximizing production of cellulolytic and hemicellulolytic enzymes. Under the optimized condition, the production of FPase, endoglucanase, ${\beta}$-glucosidase, xylanase, and ${\beta}$-xylosidase was achieved at 23, 663, 88, 1,633, and 90 units/g of dry substrate, respectively. The multi-enzyme extract was highly efficient in the saccharification of alkaline-pretreated rice straw, corn cob, and corn stover. In comparison with commercial cellulase preparations, the BCC199 enzyme mixture was able to produce remarkable yields of glucose and xylose, as it contained higher relative activities of ${\beta}$-glucosidase and core hemicellulases (xylanase and ${\beta}$-xylosidase). These results suggested that the crude enzyme extract from A. aculeatus BCC199 possesses balanced cellulolytic and xylanolytic activities required for the efficient saccharification of lignocellulosic biomass feedstocks, and supplementation of external ${\beta}$-glucosidase or xylanase was dispensable. The work thus demonstrates the high potential of A. aculeatus BCC199 as a promising producer of lignocellulose-degrading enzymes for the biomass conversion industry.

• Journal of the Korean Solar Energy Society
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• 제30권4호
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• pp.71-78
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• 2010

Investigation of the effective soil thermal conductivity(k) is the first step in designing the ground loop heat exchanger(borehole) of a geothermal heat pump system. The line source method is required by New and Renewable Energy Center of Korea Energy Management Corporation in analyzing data obtained from thermal response tests. Another important factor in designing the ground loop heat exchanger is the borehole thermal resistance($R_b$). There are two methods to evaluate $R_b$ : one is to use a line source method, and the other is to use a shape factor of the borehole. In this study, we demonstrated that the line source method produces better results than the shape factor method in evaluating $R_b$. This is because the borehole thermal resistance evaluated with the line source method characteristically reduces the temperature differences between an actual and a theoretical thermal behaviors of the borehole. Evaluation of $R_b$ requires soil volumetric heat capacity. However, the effect of the soil volumetric heat capacity on the borehole thermal resistance is very small. Therefore, it is possible to use a generally accepted average value of soil volumetric heat capacity($=2MJ/m^3{\cdot}K$) in the analysis. In this work, it is also shown that an acceptable range of the initial ignoring time should be in the range of 8~16hrs. Thus, a mean value of 12 hrs is recommended.

• Proceedings of the Korea Water Resources Association Conference
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• 한국수자원학회 2008년도 학술발표회 논문집
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• pp.389-394
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• 2008

The purpose of this research was to develop a methodology to determine whether conjunctive surface water and groundwater management could significantly reduce deficits in a river basin with a relatively limited alluvial aquifer. The Geum River basin is one of major river basins in South Korea. The upper region of the Geum River basin is typical of many river basins in Korea where the shape of river basin is narrow with small alluvial aquifer depths from 10m to 20m and where most of the groundwater pumped comes quickly from the steamflow. The basin has two surface reservoirs, Daecheong and Yongdam. The most recent reservoir, Yongdam, provides water to a trans-basin diversion, and therefore reduces the water resources available in the Geum River basin. After the completion of Yongdam reservoir, the reduced water supply in the Geum basin resulted in increasing conflicts between downstream water needs and required instream flows, particularly during the low flow season. Historically, the operation of groundwater pumping has had limited control and is administered separately from surface water diversions. Given the limited size of the alluvial aquifer, it is apparent that groundwater pumping is essentially taking its water from the stream. Therefore, the operation of the surface water withdrawals and groundwater pumping must be considered together. The major component of the conjunction water management in this study is a goal-programmin g based optimization model that simultaneously considers surface water withdrawals, groundwater pumping and instream flow requirements. A 10-day time step is used in the model. The interactions between groundwater pumping and the stream are handled through the use of response and lag coefficients. The impacts of pumping on streamflow are considered for multiple time periods. The model is formulated as a linear goal-programming problem that is solved with the commercial LINGO optimization software package.

• IMMUNE NETWORK
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• 제4권2호
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• pp.73-80
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• 2004

Viruses are obligate intracellular parasites which cause infection by invading and replicating within cells. The immune system has mechanisms which can attack the virus in extracellular and intracellular phase of life cycle, and which involve both non-specific and specific effectors. The survival of viruses depends on the survival of their hosts, and therefore the immune system and viruses have evolved together. Immune responses to viral infection may be variable depending on the site of infection, the mechanism of cell-to-cell spread of virus, physiology of the host, host genetic variation, and environmental condition. Viral infection of cells directly stimulates the production of interferons and they induce antiviral state in the surrounding cells. Complement system is also involved in the elimination of viruses and establishes the first line of defence with other non-specific immunity. During the course of viral infection, antibody is most effective at an early stage, especially before the virus enters its target cells. The virus- specific cytotoxic T lymphocytes are the principal effector cells in clearing established viral infections. But many viruses have resistant mechanism to host immune responses in every step of viral infection to cells. Some viruses have immune evasion mechanism and establish latency or persistency indefinitely. Furthermore antibodies to some viruses can enhance the disease by the second infection. Immune responses to viral infection are very different from those to bacterial infection.

• Journal of the Computational Structural Engineering Institute of Korea
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• 제16권3호
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• pp.311-319
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• 2003

This paper aims at investigating the exact dynamic response of the system undergoing a exponential impact force from the viewpoints of conservations of momentum and energy. The midpoint method applied in the Newmark's family algorithm is found to be identical to the case of the application of the trapezoidal method which provides conservations of momentum and energy. For the linear impact force the mid point, the trapezoidal and the (n+1) point method exactly meet the conservation characteristics independent of the size of integration interval. On the other hand, constants for the dynamic motion resulting from the nonlinear impact are underestimated or overestimated by these method mentioned above. To overcome this indispensible error, the Simpson 1/3 method as one of multi step methods whose advantages is to use longer time interval with the same number of evaluation functions is adopted for the exact conservations of momentum and energy. Moreover, the suggested method is expected to expand the similar algorithm for the general dynamic motion including finite rotations.

• Journal of Korean Society of Steel Construction
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• 제23권3호
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• pp.397-404
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• 2011

In this paper, a research for the dynamic wheel loads of a 3D vehicle model, which relates to a tire-enveloping model, is carried out. A single truck with four axles is modeled as a 10-D.O.F. vehicle by modeling both contact length of tires and pitching of tandem spring axles. The dynamic equations of the vehicle are obtained using the Lagrange's equation, the solution of the equations is calculated by Newmark-${\beta}$ method. The validity of the developed 3D vehicle model is demonstrated by comparing results obtained from the proposed method with those from experimental data. The maximum impact factors of tire force are evaluated according to the various step bumps on which a 24-ton dump truck is running.

• Convergence Security Journal
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• 제15권3_1호
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• pp.107-114
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• 2015

Since 2002, information security management system has been implemented (ISMS) certification scheme whilst providing telecommunications services to enhance the level of enterprise information security was ongoing and Prevent accidents and avoid spread of infringement, such as rapid response and there is a lot of it came true. However, this system is the protection of the country or the investment company, as part of the actual information on how management affects the performance came from or how measures are still lacking for. In this study, the companies have their own privacy ISMS certification measures the level of activity continued to improve information security performance measures and methodology are presented. The government is also based on the validity of the certification system to ensure the overall implementation of the ISMS itself is this a step increase effective information security system is to be certified in advance to prevent security incidents and to improve business performance to help.

• Journal of Periodontal and Implant Science
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• 제50권5호
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• pp.281-290
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• 2020

Purpose: The aim of this study was to compare microRNA (miRNA) gene expression in saliva using miRNA polymerase chain reaction (PCR) arrays in healthy and aggressive periodontitis (AP) patients. Methods: PCR arrays of 84 miRNAs related to the human inflammatory response and autoimmunity from the saliva samples of 4 patients with AP and 4 healthy controls were performed. The functions and diseases related to the miRNAs were obtained using TAM 2.0. Experimentally validated targets of differentially expressed miRNAs were obtained from mirTarBase. Gene ontology terms and pathways were analyzed using ConsensusPathDB. Results: Four downregulated miRNAs (hsa-let-7a-5p, hsa-let-7f-5p, hsa-miR-181b-5p, and hsa-miR-23b-3p) were identified in patients with AP. These miRNAs are associated with cell death and innate immunity, and they target genes associated with osteoclast development and function. Conclusions: This study is the first analysis of miRNAs in the saliva of patients with AP. Identifying discriminatory human salivary miRNA biomarkers reflective of periodontal disease in a non-invasive screening assay is crucial for the development of salivary diagnostics. These data provide a first step towards the discovery of key salivary miRNA biomarkers for AP.