• Pediatric Gastroenterology, Hepatology & Nutrition
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• 제26권5호
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• pp.266-276
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• 2023

Purpose: Human milk oligosaccharides (HMOs) may be genetically determined based on the secretor and Lewis status of the mother. This study aims to determine the HMO profile and the secretor and Lewis gene status of Indonesian lactating mothers. Methods: Baseline data of 120 mother-infant pairs between 0-4 months post-partum obtained from a prospective longitudinal study was used. The concentrations of 2'-fucosyllactose (2'FL), lacto-N-fucopentaose I (LNFP I), lacto-N-tetraose (LNT), lacto-N-neotetraose (LNnT), 3'-sialyllactose (3'SL), and 6'-sialyllactose (6'SL) were measured. Genetic analysis was performed for mothers using targeted next-generation sequencing and Sanger sequencing. Wild-type AA with the rs1047781 (A385T) polymorphism was categorized as secretor positive, while heterozygous mutant AT was classified as a weak secretor. The presence of rs28362459 (T59G) heterozygous mutant AC and rs3745635 (G508A) heterozygous mutant CT genes indicated a Lewis negative status, and the absence of these genes indicated a positive status. Subsequently, breast milk was classified into various groups, namely Group 1: Secretor+Lewis+ (Se+Le+), Group 2: Secretor-Lewis+ (Se-Le+), Group 3: Secretor+Lewis-(Se+Le-), and Group 4: Secretor-Lewis- (Se-Le-). Data were analyzed using the Mann-Whitney and Kruskal-Wallis rank tests, and a p-value of 0.05 indicated statistical significance. Results: A total of 58.3% and 41.7% of the samples had positive and weak secretor statuses, respectively. The proportion of those in Group 1 was 85%, while 15% were Group 3. The results showed that only 2'FL significantly differed according to the secretor status (p-value=0.018). Conclusion: All Indonesian lactating mothers in this study were secretor positive, and most of them had a Lewis-positive status.

• 기본간호학회지
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• 제12권1호
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• pp.30-37
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• 2005

Purpose: This study was a descriptive research to investigate the health behavior, health status and self-efficacy according to the concepts of Sasangin. Method: Participants in this study were 214 nurses in hospitals in Seoul, Kyunggi and B city. Data were collected using interview with questionnaires from Oct.2 to Nov.30, 2003. The measurement tools were the QSCC II by Kim et al., Health Behavior by Kim, CMI by Nam and self-efficacy by Sherer, all of which have resported reliability. For the purpose of the study, the collected data were analyzed by Frequency, ANOVA, and Pearson correlation coefficients. Results: 1) There was a significant difference in health behavior according to constitution (F=1 273, p=.020). 2) There was a negative correlation between health behavior and health status for Taeumin (r=-.376, p=.002). There was also a negative correlation between health status and self-efficacy for Taeumin (r=-.271, p=.029). Conclusion: The results of this study showed that there were significant differences in health behavior, health status and self-efficacy for the participants according to the constitution of each nurse. So, based on these results, determining and fully understanding the client's constitution are important as these are the foundations of Eum-Yang and personal characteristics. Therefore, we have to consider the constitution when we provide nursing care. However, this study did not show a correlation between health behavior, health status and self efficacy for Soyangin and Soeumin. Further research is needed to determine if there is a relation between these variables according to various constitutions.

• 대한원격탐사학회지
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• 제38권1호
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• pp.73-82
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• 2022

Marine fisheries resources face major anthropogenic threat from unregulated fishing activities; thus require precise detection for protection through marine surveillance. Korea developed an efficient land-based small fishing vessel monitoring system using real-time V-Pass data. However, those data directly do not provide information on fishing activities, thus further efforts are necessary to differentiate their activity status. In Korea, especially in Busan, longlining is practiced by many small fishing vessels to catch several types of fishes that need to be identified for proper monitoring. Therefore, in this study we have improved the existing fishing status classification method by applying Hidden Markov Model (HMM) on V-Pass data in order to further classify their fishing status into three groups, viz. non-fishing, longlining and other types of fishing. Data from 206 fishing vessels at Busan on 05 February, 2021 were used for this purpose. Two tiered HMM was applied that first differentiates non-fishing status from the fishing status, and finally classifies that fishing status into longlining and other types of fishing. Data from 193 and 13 ships were used as training and test datasets, respectively. Using this model 90.45% accuracy in classifying into fishing and non-fishing status and 88.23% overall accuracy in classifying all into three types of fishing statuses were achieved. Thus, this method is recommended for monitoring the activities of small fishing vessels equipped with V-Pass, especially for detecting longlining.

• 보건행정학회지
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• 제31권1호
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• pp.74-90
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• 2021

Background: It is getting important to improve the oral health status of the elderly because oral health status may affect their health status of the whole body. In this respect, we aimed to explore the association of oral health status and behavior factors with self-rated health status by sex. Methods: Using the data from the 7th Korea National Health and Nutrition Examination Survey for health surveys and oral examinations (2016-2018), we analyzed a total of 3,070 people aged 65 or older (men: 1,329; women: 1,741). Our dependent variable, self-rated health status, was divided into two groups: not good (bad and very bad) and good (very good, good, and fair), whereas our independent variables of interest were oral health status and behavior factors. In addition to descriptive analysis and the Rao-Scott chi-square test, reflecting survey characteristics, we conducted hierarchical multivariable logistic regression analyses adjusted for socio-demographics and health status and behavior factors. All analyses were stratified by sex. Results: The proportion of people having 'not good' self-rated health was 36.5% in women but 24.5% in men. In a model adjusted for all covariates, the self-rated health status showed significant association with the self-rated oral health status. For example, in men, the risk of having 'not good' self-rated health was high in people having 'poor' (odds ratio [OR], 5.31; 95% confidence interval [CI], 2.34-12.03) self-rated oral health status and in those having 'fair' (OR, 4.03; 95% CI, 1.68-9.70) in comparison with those having 'good' self-rated oral health status. Dental status regarding speaking difficulty seemed to be very important in influencing self-rated health status. For instance, in women, compared to people having 'no discomfort' speaking difficulty, the risk of having 'not good' self-rated health was high in people having 'not bad' (OR, 1.60; 95% CI, 1.14-2.24) and 'discomfort' (OR, 1.79; 95% CI, 1.30-2.47) speaking difficulty. The covariates significantly associated with the risk of having 'not good' self-rated health were: physical activity, chronic disease, stress, and body mass index in both sexes; health insurance type and drinking only in men; and economic activity only in women. Conclusion: Oral health status and behavioral factors were associated with self-rated health status among the elderly, differently by sex. This suggests that public health policies toward better health in the elderly should take their oral health status and oral health behaviors into account in a sex-specific way.

• Asian Pacific Journal of Cancer Prevention
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• 제14권12호
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• pp.7621-7628
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• 2013

Human epidermal growth factor receptor (HER) status is an important prognostic factor in breast cancer. There is no globally accepted method for determining its status, and which method is most precise is still a matter of debate. We here analyzed HER2 mRNA expression by quantitative reverse transcription-PCR (qRT-PCR) and HER2 DNA amplification using multiplex ligation-dependent probe amplification (MLPA). In parallel, we performed a routine evaluation of HER2 protein by immunohistochemistry (IHC). To assess the accuracy of the RT-PCR and MLPA techniques, a combination of IHC and fluorescence in situ hybridization (FISH) was used, substituting FISH when the results of IHC were ambiguous (2+) and for those IHC results that disagreed with MLPA and qRT-PCR, this approach being termed IHC-FISH. The IHC results for four samples were not compatible with the MLPA and qRT-PCR results; the MLPA and qRT-PCR results for these samples were confirmed by FISH. The correlations between IHC-FISH and qRT-PCR or MLPA were 0.945 and 0.973, respectively. The ASCO/CAP guideline IHC/FISH correlation with MLPA was (0.827) and with RT-PCR was (0.854). The correlations between the IHC results (0, 1+ as negative, and 3+ as positive) and qRT-PCR and MLPA techniques were 0.743 and 0.831, respectively. Given the shortcomings of IHC analysis and greater correlations between MLPA, qRT-PCR, and FISH methods than IHC analysis alone with each of these three methods, we propose that MLPA and real-time PCR are good alternatives to IHC. However a suitable cut-off point for qRTPCR is a prerequisite for determining the exact status of HER2.

• 대한안전경영과학회지
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• 제17권3호
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• pp.97-104
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• 2015

The study is conducted in order to identify whether there is difference in laboratory safety management committee and safety manager appointment for type of institutes(university, research institute, enterprise institute). The study conducted statistical analysis of 2484 institutes (university, research institute, enterprise institute) that attended 'current status of laboratory safety management' by year(number of current status participation). As a result, university showed increase in forming safety management committee as the number of current status(year) increases. The number of safety management committee held were the highest amongst all institutes being 2 held/2 year. Furthermore, period of safety management committee held at university and research institutes are decreasing stately. For 2014, the rate of hosting periodic committee and temporary committee simultaneously when necessary are increasing. The rate of appointing safety manager who is in charge of laboratory safety is increasing in university, but it is decreasing in research institute and enterprise institute. The work pattern of safety manager in university is increase in exclusive duties and decrease in adjunct duties, while work pattern in research institute and enterprise institute is more on the contract duties.

• 한국의학물리학회:학술대회논문집
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• 한국의학물리학회 2002년도 Proceedings
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• pp.171-173
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• 2002

Present status of the proton therapy project at the Wakasa Wan Energy Research Center, Japan, is reported. Construction of the accelerator system was finished in 2001, followed by some trials of the production of the flat clinical irradiation field for the clinical usage. After the patient positioning system with X-ray CT was verified, the first clinical trial was started for two patients with prostate cancer.

• 한국의류학회지
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• 제35권5호
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• pp.612-620
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• 2011

This study provides information and suggest a direction for the future research needs of medical attire as a high value-added industry. A total of 69 studies on medical attire were categorized and analyzed for the study subject, study method, and study locations. As per the time period, until the mid-80s, almost no research on medical attire was conducted; however, the number has increased as of late. The distribution by subject was in the order of status investigation, design development, material research, textile design, and sizing system, and especially there was significant focus on wearing status and design development that has rapidly increased over the last 10 years. The distribution by target was in the order of adult patients, elderly patients, doctors, nurses, and juvenile patients. There are many studies on the wearing status and design development of adult patient attire as well as on the textile design and sizing system study for doctor's attire. The distribution by study method was in the order of survey and interview, research and development, dressing evaluation, real resources analysis, and physical property experiments. Through the results of the analysis on the study subject and target, it was found that the wearing status investigation for adult patient attire through a survey and interview was most active. The distribution by study location was in the order of Seoul, Incheon - Gyeonggi, Busan - Ulsan - Gyeongnam, and suggested that a study on patient attire in Dajeon - Chungcheong and Jeonbuk was inadequate.

• 한국항해항만학회:학술대회논문집
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• 한국항해항만학회 2018년도 추계학술대회
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• pp.368-369
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• 2018

본 논문은 IMO 차세대 해양안전종합관리체계 운영시스템 구축 사업과 주요 통신 인프라인 초고속 해상무선통신망(LTE-Maritime) 구축 사업의 현황과 향후 계획에 대해서 설명하였다.

• 한국경영과학회지
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• 제1권1호
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• pp.37-44
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• 1976