• Restorative Dentistry and Endodontics
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• 제43권3호
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• pp.18.1-18.12
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• 2018

Objectives: This study compared the retention of BioAggregate (BA; Innovative BioCeramix) and mineral trioxide aggregate (MTA; Angelus) as coronal plugs after applying different intracanal medications (ICMs) used in regenerative endodontic. Materials and Methods: One-hundred human maxillary central incisors were used. The canals were enlarged to a diameter of 1.7 mm. Specimens were divided into 5 groups (n = 20) according to the ICM used: calcium hydroxide (CH), 2% chlorhexidine (CHX), triple-antibiotic paste (TAP), double-antibiotic paste (DAP), and no ICM (control; CON). After 3 weeks of application, ICMs were removed and BA or MTA were placed as the plug material (n = 10). The push-out bond strength and the mode of failure were assessed. The data were analyzed using 2-way analysis of variance, the Tukey's test, and the ${\chi}^2$ test; p values < 0.05 indicated statistical significance. Results: The type of ICM and the type of plug material significantly affected bond strength (p < 0.01). Regardless of the type of ICM, BA showed a lower bond strength than MTA (p < 0.05). For MTA, CH showed a higher bond strength than CON, TAP and DAP; CHX showed a higher bond strength than DAP (p < 0.01). For BA, CH showed a higher bond strength than DAP (p < 0.05). The mode of failure was predominantly cohesive for BA (p < 0.05). Conclusions: MTA may show better retention than BA. The mode of bond failure with BA can be predominantly cohesive. BA retention may be less affected by ICM type than MTA retention.

• 한국임상약학회지
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• 제24권2호
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• pp.106-114
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• 2014

Purpose: Recent investigations suggest that the antiplatelet effect of clopidogrel may be decreased when this medication is taken together with certain proton pump inhibitors (PPIs). However, there has been no study conducted in Korea regarding the clinical effect of clopidogrel-PPI interaction. This study targeted patients who received stents to investigate the effect of the concomitant use of clopidogrel and PPIs on the occurrence of adverse cardiovascular events in Korean patients. Methods: The patients who received a stent insertion at the Yeouido St. Mary's Hospital between January 2010 and April 2011 were included. The patients were divided into two groups, clopidogrel and clopidogrel + PPI, and followed for 12 months after the date of stent insertion using prescription history and medical records. The recurrence rates of the cardiovascular events among the two patient groups were statistically analyzed. Results: There was no difference between the two groups in the basic characteristics of the 157 patients in the clopidogrel group and the 62 patients in the clopidogrel+PPI group. Simple logistic regression showed a significantly higher rate of re-hospitalization in the clopidogrel+PPI group (OR=1.893, 95% CI 1.040-3.445, p=0.037). However, the results of the multivariate logistic regression of the variables found to have statistical significance by crosstabulation showed no significant difference in the rate of adverse cardiovascular events or re-hospitalization between the two groups. Conclusions: There was no significant difference between the clopidogrel and clopidogrel+PPI group among new patients with cardiovascular stents with respect to the occurrence of revascularization procedures, stent thrombosis, or chest pain, or with respect to the re-hospitalization rate for all cardiovascular events.

• 정보교육학회논문지
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• 제14권1호
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• pp.111-121
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• 2010

본 연구는 초등학교 수준에서의 게임식 로봇교육프로그램을 개발하고 적용하여 논리적 사고력의 변화 비교를 통하여 교육적 효과를 검증 하였다. 이를 위해 경남 남해군 S초등학교 6학년 남학생 12명을 실험집단으로 선정하고 개발된 게임식 로봇교육프로그램 32차시를 적용하여 사전 사후 논리적 사고력검사 결과를 분석 하였다. 본 연구에서 게임식 로봇교육프로그램을 적용한 결과 실험집단의 논리적사고력 변화 결과는 통계적으로 유의미한 차이가 나타났다. 이는 게임 로봇교육프로그램이 논리적 사고력에 긍정적인 효과가 있음을 의미하며 게임식 로봇교육이 학생들의 논리 및 사고력향상에 긍정적인 교육적 효과가 있으며 학생들의 로봇교육에 대한 흥미와 관심을 높이는데 영향을 끼칠 수 있음을 알 수 있었다.

• 대한치과마취과학회지
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• 제11권2호
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• pp.125-132
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• 2011

Background: Adult patients with intellectual disabilities often strongly resist the anesthetic administration for dental procedures. This study aimed to evaluate the effect of midazolam premedication in improving the cooperation level of patients who are likely to be combative and irritated during general anesthesia (GA) induction. Methods: The patients who had received dental treatment under ambulatory GA for more than two times were included. And we selected 13 patients total that needed physical restraint or ketamine IM prior to induction at the first GA, and were prescribed midazolam tablet (7.5-15 mg) at the following GA. We reviewed pre-anesthetic records and anesthesia records, and evaluated cooperative levels of patients (4 levels scale) during anesthesia induction and recovery time retrospectively. Results: All 13 patients (Male 11, Female 2) had severe mental disabilities. The average age of the patients was 24 ${\pm}$ 7 (13-37) years and their average weight was 58 ${\pm}$ 16 (34-91) kg. At the first GA, 10 patients needed physical restraint prior to induction (level 3). And 3 patients were so poorly cooperative that the induction procedure was performed after intramuscular injection of ketamine (level 4). But after the midazolam intake, 7 patients were willing to receive the anesthetic induction (level 1, 2), and 6 patient needed physical restraint (P < 0.05). There were no statistical differences in the duration of general anesthesia and postoperative recovery. Conclusions: Oral intake of midazolam was effective in improvement of cooperation without any complications.

• Restorative Dentistry and Endodontics
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• 제40권2호
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• pp.104-112
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• 2015

Objectives: This study was performed to investigate the effects of different intracanal medicaments on chemical structure and microhardness of dentin. Materials and Methods: Fifty human dentin discs were obtained from intact third molars and randomly assigned into two control groups and three treatment groups. The first control group received no treatment. The second control group (no medicament group) was irrigated with sodium hypochlorite (NaOCl), stored in humid environment for four weeks and then irrigated with ethylenediaminetetraacetic acid (EDTA). The three treatment groups were irrigated with NaOCl, treated for four weeks with either 1 g/mL triple antibiotic paste (TAP), 1 mg/mL methylcellulose-based triple antibiotic paste (DTAP), or calcium hydroxide [$Ca(OH)_2$] and finally irrigated with EDTA. After treatment, one half of each dentin disc was subjected to Vickers microhardness (n = 10 per group) and the other half was used to evaluate the chemical structure (phosphate/amide I ratio) of treated dentin utilizing attenuated total reflection Fourier transform infrared spectroscopy (n = 5 per group). One-way ANOVA followed by Fisher's least significant difference were used for statistical analyses. Results: Dentin discs treated with different intracanal medicaments and those treated with NaOCl + EDTA showed significant reduction in microhardness (p < 0.0001) and phosphate/amide I ratio (p < 0.05) compared to no treatment control dentin. Furthermore, dentin discs treated with TAP had significantly lower microhardness (p < 0.0001) and phosphate/amide I ratio (p < 0.0001) compared to all other groups. Conclusions: The use of DTAP or $Ca(OH)_2$ medicaments during endodontic regeneration may cause significantly less microhardness reduction and superficial demineralization of dentin compared to the use of TAP.

• 한국정보처리학회논문지
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• 제4권11호
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• pp.2786-2800
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• 1997

본 논문에서는 전송채널의 메모리 (전송오류가 발생하는 형태상의 통계적 상관관계) 특성이 현재 실제 널리 사용되고 있는 오류제어 프로토콜의 성능에 어느 정도 영향을 끼치는 가를 연구하고자 한다. 먼저 각 정보블록의 오류발생 형태는 전송오류가 발생하거나 하지 않는 두 가지 상태를 갖는 마르코프 오류모델을 따른다고 가정하고, 이 모델을 다중－거부 옵션을 가진 실제적인 LAP 계열 프로토콜들, 즉 LAPB/D/M 절차들에 적용하여 전송성능과 반응시간에 대한 이산－시간 해석을 행한다. 수치해석을 통해 마르코프 오류모델 하에서 분석된 실제적인 LAP 계열 프로토콜의 전송성능과 전송지연 특성이 일반적으로 가정되는 상호독립적 오류모델을 사용한 결과보다 개선된다는 점을 관찰하고 오류제어 프로토콜의 정확한 성능분석을 위해서는 집중형 오류모델을 사용해야 한다는 결론을 도출한다. 또한 사용자가 인지하는 반응시간의 정확한 평가를 위해 평균과 표준편차를 동시에 고려한 새로운 반응시간 척도를 제안하고, 이를 평균으로만 반응시간을 평가할 경우와 비교하여 새로운 척도가 파라미터 변이에 대해 훨씬 민감하게 반응시간을 평가할 수 있다는 효율성을 입증한다．

• Archives of Reconstructive Microsurgery
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• 제7권1호
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• pp.1-9
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• 1998

From January 1985 to February 1997, 96 patients had undergone the free vascularized groin flap on the upper and lower extremities with microsurgical technique at the department of orthopaedic surgery, Yonsei University College of Medicine. The results were as follows: 1. Average age at the time of operation was 24.9 years. and there were 71 men and 25 women and mean follow up was 62.4 months. 2. The lesion site was 82 cases on the lower extremity: foot(40), leg(20), ankle(13), and 14 cases on the upper extremity: forearm(6), elbow(3), hand(3), wrist(2). 3. The anatomical classification of the superficial circumflex iliac artery was as follows: 1) 39.8% of common origin with superficial inferior epigastric artery, 2) 30.1% of isolated origin and absent superficial inferior epigastric artery, 3) 13.3% of separate origin, 4) 16.9% of origin from the deep femoral artery. 4. There was no statistical significance on arterial anastomosis between end to end and end to side, and on venous anastomosis(end to end) between one vein and two veins. 5. The success rate was average 84.4% in 81 of 96 cases. 6. In the 15 failed cases, the additional procedures were performed: 5 cases of free vascularized scapular flap, 6 cases of full thickness skin graft, 2 cases of cross leg flap, 1 case of latissimus dorsi flap, 1 case of split thickness skin graft. In conclusion, the free vascularized groin flap can be considered as the treatment of choice for the reconstruction of the extensive soft tissue injury on the extremities, and show the higher success rate with the experienced surgeon.

• 패션비즈니스
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• 제14권6호
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• pp.39-52
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• 2010

Interests in creating three-dimensionally designed fabric materials are growing rapidly in the sectors of the fashionable textiles with the creativity, new functions, and aesthetics. A number of finishing methods have been developed and proposed to add or create new functions and designs for silk fabrics. Due to the strong hydrogen bonds between the molecules of silk fibroins, the thermal treatment methods used in thermoplastic fiber processing, which can easily deform the synthetic filament fabrics to endow three-dimensional appearance to the fabrics, are not applicable to the silk fabric treatment. In order to modify the fine structure of silk fiber, neutral salt solution treatment methods have been suggested. In this study, the effect of the calcium nitrate solution on the physical and mechanical properties of silk fabrics was investigated by using the KES(Kawabata Evaluation System) equipment. Based on these findings, relationships between parameters, for example, the thickness and the compressional energy, the thickness and the compressional linearity, and the air permeability and the pore area statistical analysis were investigated. The relationships between the process parameters such as treatment temperature/time and the resulting fabric property parameters were also analyzed by using several SAS procedures.

• 한국수자원학회논문집
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• 제52권10호
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• pp.657-669
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• 2019

수공구조물의 설계 시 빈도해석을 통해 수문자료의 통계적 특성을 고려하여 설계빈도에 대한 정확한 확률수문량을 산정하는 것은 매우 중요한 절차이다. 지역빈도해석은 대상 지점의 자료만을 이용하여 확률수문량을 산정하는 지점빈도해석과 달리 수문학적으로 동질한 것으로 판단되는 주변지점들의 자료를 모두 포함하여 빈도해석을 수행하므로 미계측 지점 또는 자료 보유년수가 짧은 지점에서 보다 정확한 확률수문량 산정이 가능하다. 본 총설논문에서는 이러한 지역빈도해석 기법을 수문자료의 특성에 따라 정상성 지역빈도해석과 비정상성 지역빈도해석으로 구분하고, 각 방법의 기본이론과 절차 및 관련 연구를 홍수지수법을 중심으로 상세히 설명하였으며 최신 연구동향을 정리하였다. "홍수량 산정 표준지침"의 개정을 통해 포함되는 정상성 지역빈도해석에 대해 언급하고, 비정상성 지역빈도해석과 관련한 향후 연구주제를 기술하며 논문을 마무리 한다.

• Archives of Plastic Surgery
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• 제48권6호
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• pp.599-606
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• 2021

Background Postoperative dehiscence and surgical site infection after spinal surgery can carry serious morbidity. Multidisciplinary involvement of plastic surgery is essential to minimizing morbidity and achieving definitive closure. However, a standardized approach is lacking. The aim of this study was to identify effective reconstructive interventions for the basis of an evidence-based management protocol. Methods A retrospective review was performed at a single tertiary institution for 45 patients who required 53 reconstruction procedures with plastic surgery for wounds secondary to spinal surgery from 2010 to 2019. Statistical analysis was performed for demographics, comorbidities, and treatment methods. Primary outcomes were postoperative complications, including dehiscence, seroma, and infection. The secondary outcome was time to healing. Results The overall complication rate was 32%, with dehiscence occurring in 17%, seroma in 15% and infection in 11% of cases. Median follow-up was 10 months (interquartile range, 4-23). Use of antibiotic beads did not affect rate of infection occurrence after wound closure (P=0.146). Use of incisional negative pressure wound therapy (iNPWT) was significant for reduced time to healing (P=0.001). Patients treated without iNPWT healed at median of 67.5 days while the patients who received iNPWT healed in 33 days. Demographics and comorbidities between these two groups were similar. Conclusions This data provides groundwork for an evidence-based approach to soft tissue reconstruction and management of dehiscence after spinal surgery. Timely involvement of plastic surgery in high-risk patients and utilization of evidence-based interventions such as iNPWT are essential for improving outcomes in this population.