• Journal of Pharmaceutical Investigation
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• v.34 no.5
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• pp.379-383
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• 2004

Statistical interpretations in a bioequivalence trial are considered and studied when the missing observations occurred in $2\;{\times}\;2$ crossover experiment. Patel (1985) suggested the approximate test procedures for carryover effect and drug effect in $2\;{\times}\;2$ crossover design when some of data are missing in the second period. A modified Patel method is newly proposed to the bioequivalence trial and it is compared with the current method through the simulation study.

• The Korean Journal of Applied Statistics
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• v.2 no.1
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• pp.18-34
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• 1989

The problem of simultaneously estimating the pairwise differences of means of four independent normal populations with equal variances is considered. A statistical computing procedure involving a trivariate t density constructs the exact confidence intervals with simultaneous co verage probability equal to $1-\alpha$. For equal sample sizes, the new procedure is the same as the Tukey studentized range procedure. With unequal sample sizes, in the sense of efficiency for confidence interval lengths and experimentwise error rates, the procedure is superior to the various generalized Tukey procedures.

• Communications for Statistical Applications and Methods
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• v.11 no.2
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• pp.399-411
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• 2004

A common method of handling nonresponse in sample survey is to delete the cases, which may result in a substantial loss of cases. Thus in certain situation, it is of interest to create a complete set of sample values. In this case, a popular approach is to impute the missing values in the sample by the mean or the median of responders. The difficulty with this method which just replaces each missing value with a single imputed value is that inferences based on the completed dataset underestimate the precision of the inferential procedure. Various suggestions have been made to overcome the difficulty but they might not be appropriate for public-use files where the user has only limited information for about the reasons for nonresponse. In this note, a multiple imputation method is considered to create complete dataset which might be used for all possible inferential procedures without misleading or underestimating the precision.

• Communications for Statistical Applications and Methods
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• v.23 no.1
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• pp.33-45
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• 2016

Variance components should be estimated based on mean change when the mean of the observations drift gradually over time. Consistent estimators for the variance components are studied for a particular modeling situation with some underlying functions or drift. We propose a new variance estimator with Fourier estimation of variations. The consistency of the proposed estimator is proved asymptotically. The proposed procedures are studied and compared empirically with the variance estimators removing trends. The result shows that our variance estimator has a smaller mean square error and depends on drift patterns. We estimate and apply the variance to Nile River flow data and resting state fMRI data.

• Communications for Statistical Applications and Methods
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• v.23 no.4
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• pp.269-285
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• 2016

In this paper, a simple step-stress accelerated life test (ALT) under progressive type-II censoring is considered. Progressive type-II censoring and accelerated life testing are provided to decrease the lifetime of testing and lower test expenses. The cumulative exposure model is assumed when the lifetime of test units follows an extension of the exponential distribution. Maximum likelihood estimates (MLEs) and Bayes estimates (BEs) of the model parameters are also obtained. In addition, a real dataset is analyzed to illustrate the proposed procedures. Approximate, bootstrap and credible confidence intervals (CIs) of the estimators are then derived. Finally, the accuracy of the MLEs and BEs for the model parameters is investigated through simulation studies.

• Journal of the Korean Data and Information Science Society
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• v.18 no.4
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• pp.1005-1021
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• 2007

Traditional procedures for DNA microarray data analysis are to preprocess and normalize the gene expression data, and then to analyze the normalized data using statistical tests. Drawbacks of the traditional methods are: genuine biological signal may be unwillingly eliminated together with artifacts, the limited number of arrays per gene make statistical tests difficult to use the normality assumption or nonparametric method, and genes are tested independently without consideration of interrelationships among genes. A novel method using average rank in each array is proposed to eliminate such drawbacks. This average rank method monitors differentially regulated genes among genetically different groups and the selected genes are somewhat different from those selected by traditional P-value method. Addition of genes selected by the average rank method to the traditional method will provide better understanding of genetic differences of groups.

• Journal of Korean Society of Industrial and Systems Engineering
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• v.27 no.3
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• pp.14-20
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• 2004

The coefficient of variation(CV) which is a relatively dimensionless measure of variability is widely used to describe the variation of sample data. However, the properties of CV distribution are little available and few research has been done on estimation and interpretation of CV. In this paper, we give an outline of statistical properties of coefficient of variation and design of control chart based on this statistic. Construction procedures of control chart are presented. The proposed control chart is an efficient method to monitor a process variation for short production run situation. Futhermore, we evaluated the performance of CV control chart by average run length(ARL).

• Communications for Statistical Applications and Methods
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• v.8 no.1
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• pp.159-171
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• 2001

Shapiro and Wilk (1972) developed a test for exponentiality with origin and scale unknown. The procedure consists of comparing the generalized least squares estimate of scale with the estimate of scale given by the sample variance. However the test statistic is inconsistent ; that is, the power of the test will not approach 1 as the sample size increases. Hence we give a test based on the ratio of two asymptotically efficient estimates of scale. We also have conducted a power study to compare the test procedures, using Monte Carlo samples from a wide range of alternatives. It is found that the suggested statistics have higher power for the alternatives with the coefficient of variation greater that or equal to 1.

• Communications for Statistical Applications and Methods
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• v.7 no.1
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• pp.225-232
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• 2000

The linear and quadratic discrimination functions based on normal theory are widely used to classify an observation to one of predefined groups. But the discriminant functions are sensitive to outliers. A high breakdown procedure to estimate location and scatter of multivariate data is the minimum volume ellipsoid or MVE estimator To obtain high breakdown classifiers outliers in multivariate data are detected by using the robust Mahalanobis distance based on MVE estimators and the weighted estimators are inserted in the functions for classification. A samll-sample MOnte Carlo study shows that the high breakdown robust procedures perform better than the classical classifiers.

• Proceedings of the Korean Statistical Society Conference
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• 2005.11a
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• pp.159-165
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• 2005

Recently, as a result of the growing interest in modelling stationary processes with discrete marginal distributions, several models for integer valued time series have been proposed in the literature. One of theses models is the integer-valued autoregressive(INAR) models. However, when modelling with integer-valued autoregressive processes, there is not yet distributional properties of forecasts, since INAR process contain an accrued level of complexity in using the Steutal and Van Harn(1979) thinning operator 'o'. In this study, a manageable expression for the asymptotic mean square error of predicting more than one-step ahead from an estimated poisson INAR(1) model is derived. And, we present a bootstrap methods developed for the calculation of forecast interval limits of INAR(p) model. Extensive finite sample Monte Carlo experiments are carried out to compare the performance of the several bootstrap procedures.