• 한국정보컨버전스학회:학술대회논문집
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• 2008.06a
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• pp.63-70
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• 2008

The authors, Tom Karygiannis of NIST, and Bernard Eydt, Greg Barber, Lynn Bunn, and Ted Phillips of Booz Allen Hamilton, wish to thank Steven Fick, Rick Korchak, Kate Remley, Jeff Guerrieri, Dylan Williams, Karen Scarfone, and Tim Grance of NIST, and Kenneth Waldrop and Beth Mallory of Booz Allen Hamilton. These individuals reviewed drafts of this document and contributed to its technical content. The authors would also like to express their thanks to several experts for their critical review and feedback on drafts of the publication. These experts include V.C. Kumar of Texas Instruments; Simson Garfinkel of the Naval Postgraduate School; Peter Sand of the Department of Homeland Security; Erika McCallister of MITRE; and several professionals supporting Automatic Identification Technology(AIT) program offices within the Department of Defense(DoD), especially Nicholas Tsougas, Fred Naigle, Vince Pontani, Jere Engelman, and Kathleen Smith. During the public comment period we received helpful comments from the following Federal Government agencies: the US Departments of Defense, Health and Human Services, Homeland Security, Labor, and State; the Office of the Director of National Intelligence; the Office of Management and Budget; and the General Services Administration. We also received several helpful contributions from commercial industry, including comments from EPCglobal, VeriSign, and Priway. Finally, the authors wish to thank the following individuals for their comments and assistance: Brian Tiplady, Daniel Bailey, Paul Dodd, Craig K. Harmon, William MacGregor, Ted Winograd, Russell Lange, Perry F. Wilson, John Pescatore, Ronald Dugger, Stephan Engberg, Morten Borup Harning, Matt Sexton, Brian Cute, Asterios Tsibertzopoulos, Mike Francis, Joshua Slob in, Jack Harris, and Judith Myerson.

• Journal of the Computational Structural Engineering Institute of Korea
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• v.13 no.1
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• pp.75-85
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• 2000

When applying a system identification technique, which incorporates an experimental model to a corresponding finite element model of a structure, one of the major problems is the large difference in the numbers of degrees of freedom (dof) between the two models. While there are large number of dofs in a finite element model, the number of measurement points is practically limited. So it is very difficult to incorporate them. Especially rotational dofs are hard to measure. In this study a method is presented for estimating structural dynamic responses at unmeasurable locations in frequency domain. The proposed method is tested numerically and the feasibility for practical application has been demonstrated through an example structure under moving loads, where translational and rotational dofs of beam at a center point are estimated from the partial measurements of responses at accessible points.

• Korean Journal of Veterinary Research
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• v.44 no.3
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• pp.455-462
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• 2004

Change in ${\beta}$-tubulin nucleic acid and protein sequences was the only known difference between Haemonchus contortus fenbendazole (FBZ)-resistant and -susceptible isolates. This change was sufficient to determine the pathologic effect induced by FBZ treatment. This research was initiated to investigate further differences from these two isolates. Since ${\beta}$-tubulin is involved in formation of microtubule, which has functions in secretory vesicle transport, DNase activities from excretory/secretory products (ESP) of the two isolates were compared, based on pH, sensitivity to DNase inhibitors, molecular masses and production of 3'-OH. The most significant difference detected was that a 38.5 kDa DNase activity was identified from ESP of H. contortus FBZ-susceptible isolates but not from those of H. contortus FBZ-resistant isolates. However, it was shown that the 38.5 kDa DNase is expressed with similar level of activity in intestine and whole worm of H. contortus FBZ-resistant and -susceptible isolates. This result demonstrated that the secretory transport pathway of the 38.5 kDa DNase was inhibited by unknown mechanisms, which may be related with ${\beta}$-tubulin sequence change in FBZ-resistant isolates. Other DNases of 34, 36 and 37 kDa were detected from ESP of both H. contortus FBZ-resistant and -susceptible isolates. Overall DNase activities found from ESP of these two isolates were not inhibited by 10 mM EDTA at pH 5.0, but largely inhibited by pH 7.0. In addition, DNase activities in two isolates produced DNA fragments with mixtures of 3'- hydroxyls (OH) and 3'-phosphates (P) at each pH although the 3'-end labeling ratios at pH 5.0 and 7.0 were shown different. Identification of inhibition of the 38.5 kDa DNase secretion in FBZ-resistant isolates suggests existence of further differences, in addition to ${\beta}$-tubulin sequence change, in two isolates. This shows complex effect of FBZ on H. contortus biological mechanisms.

• Imaging Science in Dentistry
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• v.43 no.1
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• pp.1-6
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• 2013

Purpose: This study investigated the possible correlation between the mineralization of the second molars and the chronological age of a sample population of the state of Paraiba, Brazil. Materials and Methods: One thousand eight hundred fifty-four digitized panoramic images using a scanner of a private dental radiology service were obtained in six months. Of these, 457 were selected from patients aged 4.6 to 16 years who met certain criteria. The images were assessed twice by a radiologist with 5 years experience. A minimum interval of 30 days between the evaluations of the same patient was established. To analyze the relationship between chronological age, calcification level proposed by Demirjian et al in 1973, gender, and tooth, a multiple linear regression model was adjusted, taking age as the response variable (p<0.05). Results: The gender and calcification level were significantly correlated with the age of the patients (p<0.05). There was a significant difference between the average age of the patients' upper teeth compared to the lower ones in both genders (p<0.05). The dental development occurred earlier in female individuals than in male ones, and there was no significant difference between the right and left second permanent molars. Conclusion: It was observed that ethnic variables are related to certain parameters of age and sex identification in the Brazilian population, providing important information for forensic evaluations.

• Journal of the Ergonomics Society of Korea
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• v.28 no.3
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• pp.63-71
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• 2009

A car navigation system as an in-vehicle route guidance information (RGI) offers a state-of-the-art technological solution to driver navigation in an unfamiliar area. However, the RGI is provided by some pre-determined options in terms of the interface between a driver and a car navigation system. Drivers occasionally pass the target intersection owing to non- or late- recognizing it. This paper is examined the position of driver's turn signal operation and intersection recognition approaching at the target intersection which is difficult to identify, as a fundamental research on developing the additional RGI connecting with the turn signal control. The field experiment was conducted to measure distances of the turn signal operation and the intersection recognition from the target intersection according to left turns, right turns, and landmarks at adjacent intersection. And glance behavior to the car navigation display was evaluated by using an eye camera. The results of the field study indicate that, most case of driving, drivers operate the turn signal until 40m to 50m before coming to the target intersection. The driving simulator experiment was performed to examine the effectiveness of providing the additional RGI when drivers did not operate the turn signal approaching at the target intersection based on the results of the field study. To provide the additional RGI is effective for the intersection identification and recognition, and expected to improve the traffic safety and the comfort for drivers.

• BMB Reports
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• v.40 no.1
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• pp.15-21
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• 2007

Breast cancer is the most common malignancy among women, and mutations in the BRCA1 gene produce increased susceptibility to these malignancies in certain families. In this study, the forward 1-13 exons of breast cancer associated gene BRCA1 were cloned from breast cancer cell line ZR-75-30 by RT-PCR method. Sequence analysis showed that nine BRCA1 splice forms were isolated and characterized, compared with wild-type BRCA1 gene, five splice forms of which were novel. These splice isoforms were produced from the molecular mechanism of 5' and 3' alternative splicing. All these splice forms deleting exon 11b and the locations of alternative splicing were focused on two parts:one was exons 2 and 3, and the other was exons 9 and 10. These splice forms accorded with GT-AG rule. Most these BRCA1 splice variants still kept the original reading frame. Western blot analysis indicated that some BRCA1 splice variants were expressed in ZR-75-30 cell line at the protein level. In addition, we confirmed the presence of these new transcripts of BRCA1 gene in MDA-MB-435S, K562, Hela, HLA, HIC, H9, Jurkat and human fetus samples by RT-PCR analysis. These results suggested that breast cancer associated gene BRCA1 may have unexpectedly a large number of splice variants. We hypothesized that alternative splicing of BRCA1 possibly plays a major role in the tumorigenesis of breast and/or ovarian cancer. Thus, the identification of cancer-specific splice forms will provide a novel source for the discovery of diagnostic or prognostic biomarkers and tumor antigens suitable as targets for therapeutic intervention.

• Wind and Structures
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• v.25 no.3
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• pp.283-299
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• 2017

Two types of aerodynamic admittance function (AAF) that have been adopted in bridge aerodynamics are addressed. The first type is based on a group of supposed relations between flutter derivatives and AAFs. In so doing, the aero-elastic properties of a section could be used to determine AAFs. It is found that the supposed relations hold only for cases when the gust frequencies are within a very low range. Predominant frequencies of long-span bridges are, however, far away from this range. In this sense, the AAFs determined this way are of little practical significance. Another type of AAFs is based on the relation between the Theodorsen circulation function and the Sears function, which holds for thin airfoil theories. It is found, however, that an obvious illogicality exists in this methodology either. In this article, a viewpoint is put forward that AAFs of bluff bridge deck sections are inherently dependent on oncoming turbulent properties. This kind of dependence is investigated with a thin plate and a double-girder bluff section via computational fluid dynamics method. Two types of wind fluctuations are used for identification of AAFs. One is turbulent wind flow while the other is harmonic. The numerical results indicate that AAFs of the thin plate agree well with the Sears AAF, and show no obvious dependence on the oncoming wind fields. In contrast, for the case of bluff double-girder section, AAFs identified from the turbulent and harmonic flows of different amplitudes differ among each other, exhibiting obvious dependence on the oncoming wind field properties.

• Computers and Concrete
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• v.22 no.2
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• pp.227-237
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• 2018

Today, the modeling of concrete as a material within finite element simulations is predominantly done through nonlinear material models of concrete. In current sophisticated computational systems, there are a number of complex concrete material models which are based on theory of plasticity, damage mechanics, linear or nonlinear fracture mechanics or combinations of those theories. These models often include very complex constitutive relations which are suitable for the modeling of practically any continuum mechanics tasks. However, the usability of these models is very often limited by their parameters, whose values must be defined for the proper realization of appropriate constitutive relations. Determination of the material parameter values is very complicated in most material models. This is mainly due to the non-physical nature of most parameters, and also the large number of them that are frequently involved. In such cases, the designer cannot make practical use of the models without having to employ the complex inverse parameter identification process. In continuum mechanics, however, there are also constitutive relations that require the definition of a relatively small number of parameters which are predominantly of a physical nature and which describe the behavior of concrete very well within a particular task. This paper presents an example of such constitutive relations which have the potential for implementation and application in finite element systems. Specifically, constitutive relations for modeling the plane stress state of concrete are presented and subsequently tested and evaluated in this paper. The relations are based on the incremental theory of elastic strain-hardening plasticity in which a non-associated flow rule is used. The calculation result for the case of concrete under uniaxial compression is compared with the experimental data for the purpose of the validation of the constitutive relations used.

• Anxiety and mood
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• v.8 no.2
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• pp.86-92
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• 2012

Objective : This study investigated the relationship between the resilience and posttraumatic stress symptoms, as well as comorbid symptoms in firefighters. Methods : We collected 764 firefighters, who worked at six fire department stations in Gangwon-do. We investigated the impact of event scale-revised (IES-R), the life events checklists (LEC), Connor-Davidson resilience scale (CD-RISC), Beck depression inventory (BDI), state trait anxiety inventory (STAI) and alcohol use disorder identification test (AUDIT). Full PTSD groups, partial PTSD groups and non-PTSD groups, which were classified by IES-R scores, were compared in the LEC, CD-RISC, BDI, STAI and AUDIT, ; multiple linear regression analyses were done for independent predictors of variables. Results : Of the 764 firefighters, there were significant differences in LEC (p<0.001), CD-RISC (p<0.001), BDI (p<0.001), and AUDIT (p=0.001) among the full PTSD groups, partial PTSD groups and non-PTSD groups. However, STAI did not show significant difference among three groups. In multiple regression analysis, CD-RISC (${\beta}=-0.168$, p<0.001), LEC (${\beta}=0.211$, p<0.001) and AUDIT (${\beta}=0.115$, p=0.001) were significant predictors for IES-R. Conclusion : The results of the present study suggested that resilience might be a protective factor in PTSD and comorbid symptoms of PTSD.

• Journal of the Society of Naval Architects of Korea
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• v.28 no.2
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• pp.251-267
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• 1991

Plastic strength analysis using plastic failure mode as a limit state is adopted instead of a conventional elastic structural analysis to predict the ultimate strength of Web frame idealized by a plane frame. Linear programming arid Compact procedure are developed for determining the collapse load factor. It is found that the final results are good agreement with the results of Elasto-plastic analysis. Besides, the redundant structures like Web frame is known to have multiple failure modes. Web frame may collapse under any of the possible failure modes. Thus, the identification of these possible failure modes is necessary and very important in the reliability analysis of Web frame. In order to deal with multiple failure modes, automatic generation method of all failure modes and basic failure modes is used for selecting the dominant failure modes. The probability of failure pastic collapse of Web frame is calculated using these dominant failure modes. The safety of Web frame is asscssed and compared by performing the deterministic and probabilistic analysis.