• Progress in Medical Physics
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• v.23 no.2
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• pp.81-90
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• 2012

The effect of setup uncertainties on CTV dose and the correlation between setup uncertainties and setup margin were evaluated by Monte Carlo based numerical simulation. Patient specific information of IMRT treatment plan for rectal cancer designed on the VARIAN Eclipse planning system was utilized for the Monte Carlo simulation program including the planned dose distribution and tumor volume information of a rectal cancer patient. The simulation program was developed for the purpose of the study on Linux environment using open source packages, GNU C++ and ROOT data analysis framework. All misalignments of patient setup were assumed to follow the central limit theorem. Thus systematic and random errors were generated according to the gaussian statistics with a given standard deviation as simulation input parameter. After the setup error simulations, the change of dose in CTV volume was analyzed with the simulation result. In order to verify the conventional margin recipe, the correlation between setup error and setup margin was compared with the margin formula developed on three dimensional conformal radiation therapy. The simulation was performed total 2,000 times for each simulation input of systematic and random errors independently. The size of standard deviation for generating patient setup errors was changed from 1 mm to 10 mm with 1 mm step. In case for the systematic error the minimum dose on CTV $D_{min}^{stat{\cdot}}$ was decreased from 100.4 to 72.50% and the mean dose $\bar{D}_{syst{\cdot}}$ was decreased from 100.45% to 97.88%. However the standard deviation of dose distribution in CTV volume was increased from 0.02% to 3.33%. The effect of random error gave the same result of a reduction of mean and minimum dose to CTV volume. It was found that the minimum dose on CTV volume $D_{min}^{rand{\cdot}}$ was reduced from 100.45% to 94.80% and the mean dose to CTV $\bar{D}_{rand{\cdot}}$ was decreased from 100.46% to 97.87%. Like systematic error, the standard deviation of CTV dose ${\Delta}D_{rand}$ was increased from 0.01% to 0.63%. After calculating a size of margin for each systematic and random error the "population ratio" was introduced and applied to verify margin recipe. It was found that the conventional margin formula satisfy margin object on IMRT treatment for rectal cancer. It is considered that the developed Monte-carlo based simulation program might be useful to study for patient setup error and dose coverage in CTV volume due to variations of margin size and setup error.

• Journal of Korean Society for Atmospheric Environment
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• v.16 no.5
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• pp.453-467
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• 2000

The aim of this research is to collect and characterize fine particles (FPM:$\leq$2.5${\mu}{\textrm}{m}$) and coarse particles (CPM: 2.5~10${\mu}{\textrm}{m}$) using a low volume air sampler provided by the IAEA, at urban (Taejon) and rural area(Wonju) for a period of about two years(April 1996 to May 1998) and to promote a use of nuclear analytical techniques for air pollution studies. For the collection of airborne particulate matter (PM(sub)10), the Gent stacked filter unit sampler and polycarbonate membrane filters were employed. The concentration of trace elements in collected APM samples were determined byu instrumental Neutron Activation Analysis. For validation of the analytical data, internal quality control were implemented by using both the comparison of the analytical results of standard reference materials(NIST SRM 1648) and interlaboratory comparison for proficiency test (NAT-3). The standard uncertainty was less than 15% and Z-score of two samples were within $\pm$1. The monitoring of (PM(sub)10) mass concentration and elemental concentrations were carried out weekly. The average mass concentration of (PM(sub)10) in urban and rural areas were 59.2$\pm$36.5$\mu\textrm{g}$/㎥ and 41.4$\pm$23.7$\mu\textrm{g}$/㎥, respectively. To investigate the emission source, the enrichment factors were calculated for the fine and coarse particle fractions at two sites, respectively and these values were classified for anthropogenic and soil origin elements.

• Proceedings of the Korean Society for Noise and Vibration Engineering Conference
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• 2000.06a
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• pp.206-211
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• 2000

Demands on a quiet environment is increasing because of noisiness and annoyance due to the extended use of noisy electronic device. Determination of sound power levels of noise sources using sound pressure in a reverberation room is usually a relevant method for devices with comparatively large volume or unevenly distributed source position. This study aims to observe the contents of ISO 3741 and analyze its changes in the revised standard ISO 3741-1999. And also aims to assess the revised ISO 1999 its effectiveness and limitations with an actual application to measure the sound power level of a refrigerator.

• Proceedings of the Korean Nuclear Society Conference
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• 1996.05d
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• pp.82-87
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• 1996

An optimized method for determining beta-emitting $^{241}$ Pu in the presence of alpha-emitting nuclides was developed using a liquid scintillation counting system. PSA-level was setting using pulse-shape discrimination. The $^{241}$ Pu counting channel was adjusted for maximum value of FM using the $^{241}$ Pu standard source. The volume of scintillant was determined for the maximum value of counting efficiency. The optimized method of $^{241}$ Pu has been applied to environmental samples to measure concentration of $^{241}$ Pu in soils and mosses. Also it has been identified the origin of Pu deposited in Korea from the activity ratio $^{241}$ Pu / $^{239,240}$Pu.

• Genomics & Informatics
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• v.16 no.4
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• pp.39.1-39.3
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• 2018

The rapid increase in genetic dataset volume has demanded extensive adoption of biological knowledge to reduce the computational complexity, and the biological pathway is one well-known source of such knowledge. In this regard, we have introduced a novel statistical method that enables the pathway-based association study of large-scale genetic dataset-namely, PHARAOH. However, researcher-level application of the PHARAOH method has been limited by a lack of generally used file formats and the absence of various quality control options that are essential to practical analysis. In order to overcome these limitations, we introduce our integration of the PHARAOH method into our recently developed all-in-one workbench. The proposed new PHARAOH program not only supports various de facto standard genetic data formats but also provides many quality control measures and filters based on those measures. We expect that our updated PHARAOH provides advanced accessibility of the pathway-level analysis of large-scale genetic datasets to researchers.

• Journal of Korea Water Resources Association
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• v.43 no.12
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• pp.1029-1038
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• 2010

In meteorology Korea has 2/3 of rain of annual total rainfall at the month of Jun through Sept and it has possibility to have serious flood damage because geographically it is composed of mountainous area with steep slope which account for 70% of its country. Also, the increase of impervious layer due to industrialization and urbanization causes direct runoff, which deteriorates contamination of rivers by moving the contaminated material on the surface at the beginning of rain. In particular, the area of leisure facilities needs the management of water quality absolutely because dense population requires space of park function and place to relax and increases moving capability of non-point pollution source. For disposition of rainfall & runoff, the standard of initial rainfall, which is to be used for the computation of disposition volume, is significant factors for the runoff study of non-point pollution source, Until now, a great deal of study has been done by many researchers. However, it is the current reality that the characteristics of runoff varies according to land protection comprising river basin and the standard of initial rainfall by each researcher is not clearly defined yet. Therefore, in this research, it is suggested that, with the introduction of SOM (Self-Organizing Map), the standard of initial rainfall be determined after analyzing each sectional data by executing pattern classification about runoff and water quality data measured at the test river basin for this research.

• Journal of Radiation Protection and Research
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• v.45 no.3
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• pp.142-146
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• 2020

Background: Tritium (³H) analysis in groundwater was difficult because of its low activity. Therefore, the electrolytic enrichment method was used. To improve the detection limit and for performing simple analysis, a high-volume counting vial with the available liquid scintillation counter (LSC) was investigated. Further, it was compared with a conventional 20-mL counting vial. Materials and Methods: The LSC with the electrolytic enrichment method was used ³H analysis in groundwater. A high-volume 145-mL counting vial was compared with a conventional 20-mL counting vial to determine the counting characteristics of different LSCs. Results and Discussion: When a Quantulus LSC was used, the counting window between channels 35 and 250 was used. The background count was approximately 1.86 cpm, and the counting efficiency increased from 8% to 40% depending on the mixing ratio of the volume of sample and cocktail solution. For LSC-LB7, the optimum counting window was between 1 and 4.9 keV, which was selected by the factory (Hitachi Aloka Medical Ltd., Japan) by considering quenching using a standard external gamma source. The background count of LSC-LB7 was approximately 3.60 ± 0.29 cpm when the 145-mL vial was used and 2.22 ± 0.17 cpm when the 20-mL vial was used. The minimum detectable activity (MDA) of the 20-mL vial was greater for LSC-LB7 than for Quantulus. The MDA with the 145-mL vial was improved to 0.3 Bq/L when compared with the value of 1.6 Bq/L for the 20-mL vial. Conclusion: The counting efficiency when using the 145-mL vial was 27%, whereas it was 18% when using the 20-mL vial. This difference can be attributed to the vial volume. The figure of merit (FOM) of the 145-mL vial was four times greater than that of the 20-mL vial because the volume of the former vial is approximately seven times greater than that of the latter. Further, the MDA for ³H decreased from 1.6 to 0.3 Bq/L. The counting efficiency and FOM of LSC-LB7 was slightly less than those of Quantulus when the 20-mL vial was used. The background counting rate of the Quantulus was lower than that of the LSC-LB7.

• Journal of the Korean Society of Radiology
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• v.14 no.4
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• pp.487-494
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• 2020

The distance between the source and the detector, the diameter of the detector, and the volume effect of the radiation source result in a change in solid angle at the detector entrance, which affects the determination of detection efficiency by causing a difference in path length within the detector. A typical analysis method for calculating solid angles was useful only for a source (⁶⁰Co) with a simple geometric structure, so in this experiment, the distance between the detector and the source was measured by switching on for up to 25 cm with the reference point of window cap 0.5 cm. In addition, 450 and 1000 ㎖ Marinelli beaker of standard volumetric sources were closely adhered to the detector. For circular point sources co-axial with the detector, the change in the solid angle to the distance from the detector window is equal to half the square radius of the source versus the square radius of the detector, if the resulting relationship of the calculation analysis results in the detector being less than the radius of the source. Since the solid angular difference is 0.5 the result of Monte Carlo is acceptable. The relationship between detector and source distance is shown. Solid angles have been verified to decrease rapidly with distance. Measurement and simulation results for a volumetric source show a difference of ±1.01% from a distance of 0 cm and less than 4 % when the distance is reduced to 5 and 10 cm. It can be seen that the longer distance, the smaller efficiency angle, and the exponential increase in attenuation as the energy decreases, is reflected in the calculation of efficiency. Thus, the detection efficiency has proved sufficient for the use of solid angle and Monte Carlo codes.

• The Journal of the Acoustical Society of Korea
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• v.43 no.3
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• pp.344-350
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• 2024

A Reference Sound Source (RSS) is an important standard device employed in measuring sound power. The specifications of RSS is specified in international standards, and it is classified as a major calibration item in the field of acoustic metrology. Since the output power of RSS is affected by the supply voltage, each country needs to secure its own calibration service system. In this study, a procedure for calibrating a RSS is established based on the reverberant room conditions and uncertainty evaluation is conducted. Basically, the calibration procedure can apply a precision measurement process of acoustic power, and here, the measurement method using the reverberation chamber of ISO 3741 is applied. For this purpose, a measurement system is constructed, measurements are conducted with two types of RSS, and measurement uncertainty is evaluated. Through measurement examples, it is confirmed that the non-uniformity of the sound pressure distribution in the reverberation room and the volume measurement uncertainty contributed significantly to the overall uncertainty. Additionally, the influence of input voltage is experimentally examined to examine the uncertainty contribution that can be reflected in acoustic power measurements.

• Journal of the Korean Institute of Illuminating and Electrical Installation Engineers
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• v.25 no.12
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• pp.11-20
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• 2011

PSALI is referred to the supplementary lighting for the interior lighting under the daily lighting situation, and pursuant to the pertinent regulations in energy savings design standard and others in recent architecture works, the importance thereof has been increasing gradually coupled with the energy performance index (EPI), energy savings plan and the like as well as expansion of submittal and implementation policies. However, this type of PSALI studies indeed have a number of limitations since it has surrounding environmental conditions in direction, season, region, climate, time, opening rate, window area ratio, actual index, reflection rate of finishing materials and others in the architecture work as well as frequent changes in interior lighting environment for variables in daily light volume flowing into the interior, and others. Therefore, this study has analyzed existing advance research cases to produce the actual-sized model and scaled-down model, and installed the artificial lighting of LED light source possible to reproduce with same capability on both models. As a result of comparison and analysis of the artificial lighting with the key light, it has certain level of error rate from the scaled down lighting device in certain rate and actual model butit was noticeably significant within specific scope.