• Title/Summary/Keyword: Standard Reference Data

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Historical Control Data from 4-week Repeated Toxicity Studies in Crj:CD (SD) Rats

  • Lee, Jung-Min;Lee, Min-Ah;Do, Hyeon-Nam;Bae, Re-Ji-Na;Lee, Mi-Ju;Kim, Myoung-Jun;Jang, Ho-Song;Park, Sun-Hee;Lee, Hye-Yeong;Kang, Jin-Seok;Kang, Jong-Koo
    • Biomedical Science Letters
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    • v.18 no.3
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    • pp.268-275
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    • 2012
  • Reference ranges of standard experimental parameters are useful for comparisons in toxicology. The aim of this study was to collect data from 4-week repeated toxicity studies in Crl:CD (SD) rats, a strain widely used for toxicity and efficacy research, for establishing domestic reference values. Data on body weight, food consumption; urinalysis, hematological, and blood biochemical parameters; and organ weights were collected from 16 toxicity studies in 220 Crl:CD (SD) rats (110 males and 110 females). The studies had been performed at a single testing facility over the last 3 years and involved animals sourced from a single breeder. The findings were collated as means, standard deviations, percentages, and ranges. Urine volume, uterus weight, eosinophil, and basophil counts, and triglyceride, total bilirubin, and gammaglutamyl transpeptidase levels showed standard deviations of 30% or more. These historical control data would help to interpret the effects of test substances in routine toxicity and efficacy studies.

Hypermedia Models for CALS Environment (CALS환경에서의 하이퍼미디어 모델 적용에 관한 연구)

  • 임만택
    • The Journal of Society for e-Business Studies
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    • v.1 no.1
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    • pp.159-171
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    • 1996
  • Nowadays, multimedia and Hypermedia become hot topics in information industry. Due to high capacity of media storage and fast communication network, it is possible to exchange text data as well as image, moving picture and voice. Especially to apply hypermedia under CALS standard environment, the relation between international standard and CALS standard needs to be considered. This study introduces conceptual background and processing model of HyTime (Hypermedia Time-based Structuring Language) which is a specification of hypermedia exchange, Hyper ODA (Hyper Open Document Architecture) which is a major multimedia communication basis, MMCF (Multimedia Communication Forum), AHM(Amsterdam Hypermedia Model), and DSRM(DAVIC System Reference Model) reference model which helps determination of hypermedia communication specification Although they are international standard, provisional standard or non-standard, it discusses the Possibility of adopting them as CALS standard. Hence, this paper chooses the best recommend for CALS among these models.

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Test Results of Wide-Area Differential Global Positioning System with Combined Use of Precise Positioning Service and Standard Positioning Service Receiver

  • Kim, Kap Jin;Ahn, Jae Min
    • Journal of Positioning, Navigation, and Timing
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    • v.10 no.1
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    • pp.43-48
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    • 2021
  • Most existing studies on the wide-area differential global positioning system (WADGPS) used standard positioning service (SPS) receivers in their observation reference stations which provide the central control station global positioning system (GPS) measurements to generate augmentation data. In the present study, it is considered to apply a precise positioning service (PPS) receiver to an observation reference station which is located in the threatened jamming area. Therefore, the reference station network consists of a PPS receiver based observation reference station and SPS receiver based observation reference stations. In this case, to maintain correction performance P1C1 differential code bias (DCB) should be compensated. In this paper, P1C1 DCB estimation algorithm was applied to the PPS/WADGPS system and performance test results using measurements in the Korean Peninsula were presented.

A Standard Reference Model for Semantic Interoperability in Cloud Computing (클라우드 컴퓨팅에서의 의미 상호운용성을 위한 표준 참조 모델)

  • Jeong, Dong-Won
    • Journal of the Korea Society of Computer and Information
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    • v.17 no.8
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    • pp.71-80
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    • 2012
  • Much research has been recently accomplished for standardization in cloud computing. However, little research on standardization of data sharing and exchanging has been studied. Most of all, the corresponding standardization organization suggests no specific standardization items and reference model. This paper defines the current standardization problems and proposes a set of specific standardization items and a reference model for supporting the semantic interoperability. To achieve the goal of this paper, the overall standardization trend in cloud computing is first analyzed. Especially, this paper describes the status of standard development for addressing the semantic interoperability of data. This paper also defines the potential standardization items based on the concepts of standards in the data exchanging and management field, which are used for developing standards in various fields. Finally, the reference model is describe to show the relationships between items and overall semantic interoperability process. This paper can be used as a guideline for development of standards and also can facilitate standardization of cloud computing.

A Study on the Supporting System for Scientific Data Visualization at the National Level (국가수준의 과학데이터 시각화 지원체계에 관한 연구)

  • Park, Dong-Jin;Chae, Kyun-Shik;Ryu, Beom-Jong;Lee, Sang-Tae
    • Journal of Information Management
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    • v.42 no.2
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    • pp.85-102
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    • 2011
  • Conventionally, scientific data visualization is thought of as one of activities performed by scientists during the scientific data analysis. However, recently, there exits a set of research papers which count scientific data visualization as a independent research area. They show the research subjects for studying the scientific data visualization technology and methods. In case, a scientist or group of scientists can not solve their own visualization problem due to the unskillfulness and inexperience on using visualization tool. Therefore, it needs to help them by the systematic way for solving the problem. In this study, we analyze and propose the national level scientific visualization support system for scientists. In particular, we first analyze the existing papers and find out the critical success factors. Then, by integrating the findings of the analysis, we propose the research areas which need to be focused, and the strategic direction and specific research topics for scientific data visualization support system in national level.

Developing Data Exchange Standard between Roadside-device and Traffic Information Center in accordance with ISO 15784 (ISO 15784를 적용한 교통정보센터와 노변장치간 데이터 교환 표준 개발 _ AVI를 중심으로)

  • Lee, Sang-Hyun;Son, Seung-Neo;Kim, Nam-Sun;Cho, Yong-Sung
    • The Journal of The Korea Institute of Intelligent Transport Systems
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    • v.12 no.3
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    • pp.29-41
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    • 2013
  • This study set out to developing data exchange standard between roadside device and traffic information center fitted in a domestic environment by applying international standard ISO 15784. First, we defined message basic concept of 'Dialog' and essential elements should be defined to define the standard message for securing system compatibility by reference ISO 14817 and ISO 14827 Part 1. For defining standard message items exchanged between AVI and traffic information center, we formed Working Group under ITS Standards Technical Committee and analyzed data flow for ITS National Architecture, Standard messages of existing standards, and AVI operation messages actually operated on roadside now. So, we extracted 14 functionally needed messages and defined 28 standard messages adopting 'Dialog' concept. In case of the application protocol for data exchange standards, we defined basic requirements for securing interoperability and interchangeability considering domestic environment by analyzing reference standard of ISO 15784.

An investigation of normal range of tongue color in numerical coordinate (정상 설색의 수치적 기준에 관한 고찰)

  • Kim, Changhee;Kim, Kiwang
    • The Journal of the Society of Korean Medicine Diagnostics
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    • v.17 no.3
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    • pp.215-223
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    • 2013
  • Objectives Although tongue diagnosis is one of major diagnostic methods in east Asian traditional medicine, the standard of normal tongue color have not established. So we tried to suggest the method to establish the standard of normal tongue color range and the pilot data about the normal range. Materials and methods: 22 precedent study papers that presented the numerical data of normal (light red) tongue color were analyzed. At the same time, 46 adult people tongue color data were also collected and analyzed. Results Precedent studies showed remarkable fluctuations of the range of normal tongue color. Collected tongue color data of the 46 people showed mean Hue value 2 and standard deviation 14 in HSB system. Additionally, 3 ways of standard establishment for normal tongue color were suggested. Conclusion We suggest statistical method as a reasonable method for tongue color standard establishment and $2{\pm}14$ as a reference Hue value for normal tongue color.

Comparison of Characteristics and Dispersion of Fasting Blood Glucose Data by Administrative Districts and Gender Difference Using the 2017 'Korean Blood Glucose Reference Standard' (2017 '한국인 혈당 참조표준'을 이용한 행정구역별 남녀별 공복 혈당 데이터의 특성 및 산포성 비교)

  • Kwon, Young-Il
    • Korean Journal of Clinical Laboratory Science
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    • v.52 no.1
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    • pp.28-35
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    • 2020
  • This study aimed to investigate the differences in the upper and lower limits of the 95% distribution of fasting blood glucose (FBG) by age groups. We also analyzed the changes in the mean values and dispersion of the data using the Korean Blood Glucose Reference Standard raw data published by the National Health Insurance Service (NHIS). Furthermore, the trends among 16 administrative districts were analyzed and any gender differences were determined. We also assessed whether the study results correlated with the relative standard uncertainty, as published by the NHIS. On the dispersion analysis using the differences between the upper and lower limits of the 95% distribution of FBG by age group, there were significant differences across gender and administrative districts (P<0.05). The gender differences in FBG measurements, as published by the NHIS, were significant across different administrative districts and age groups (P<0.001). This confirmed the need to recalculate the blood glucose reference standards for men and women. No significant correlation was observed between the relative standard uncertainty, as published by NHIS, and the dispersion and number of measurements analyzed in this study. However, it showed a high correlation with the measured mean value (R2=0.95). Therefore, further research on the reference standard and uncertainty is needed.

A Study on the Current Status and Services of Energy Performance Certificates in Healthcare Building - Focused on UK and Korea (의료기관의 에너지효율등급 현황과 서비스에 관한 연구 - 영국과 한국을 중심으로)

  • Kim, Youngaee;Lee, Seungeun
    • Journal of The Korea Institute of Healthcare Architecture
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    • v.30 no.3
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    • pp.7-16
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    • 2024
  • Purpose: Medical center has consumed the energy about twice the average value of building types. So, many countries have tried sustainability and energy reduction for building types through eco friendly certificate. This study investigate the eco friendly building certificate and energy performance certificate focusing in UK and Korea, and search the characteristics of status and services of certificates. Methods: BREEAM openbook and EPC open data have been studied in UK, and green building performance certificate and EPC data in korea have been analyzed. Results: UK has eco friendly building certificate focusing on healthcare, and EPC shows the standard, benchmark reference value, so lead to the CO2 emission reduction. Primary health center and hospital show the higher value due to the dwelling unit. like a patient bed. Korea doesn't have green building certificate yet on healthcare, and EPC shows not the reference data, but the primary energy consumption. Korean cases just like in UK, clinic, public health, and outpatient center show the lower value compared to medical center, nursing home and general hospital. Implications: In Korea, it is needed for energy efficiency to have reference data information like a standard and benchmarking value for new design and construction.