• Title/Summary/Keyword: Stabilizing effect

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Effect of ethanolic extract of some anti-asthmatic herbs on clonidine and haloperidol-induced catalepsy in mice

  • Dhanalakshmi, S.;Khaserao, S.S.;Kasture, S.B.
    • Advances in Traditional Medicine
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    • v.4 no.2
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    • pp.95-99
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    • 2004
  • The ethanolic extract of some medicinal plants having anti-asthmatic activity such as Solanum xanthocarpum, Curcuma longa, Glycyrrhiza glabra, Piper longum, A. vasica, A. lebbeck, and Tinospora cordifolia was evaluated for antihistaminic and anti-cataleptic activity. The aqueous solution of ethanolic extract of S. xanthocarpum and G. glabra potentiated histamine-induced tracheal chain contractions. Whereas, C. longa, P. longum, and T. cordifolia, and A. lebbeck were without any significant effect on histamine. Only A. vasica inhibited histamine-induced tracheal chain contraction. G. glabra per se produced contraction of the tracheal chain, which was blocked by pretreatment with atropine. Single dose of S. xanthocarpum potentiated clonidine-induced catalepsy but on repeated doses (once in a day for 3 days) inhibited catalepsy. Pretreatment with ethanolic extract of C. longa, P. longum, T. cordifolia inhibited catalepsy whereas G. glabra and A. lebbeck significantly potentiated clonidine-induced catalepsy. None of the extracts inhibited haloperidol-induced catalepsy. Thus the extracts having antihistaminic activity or mast cell stabilizing activity inhibited clonidineinduced catalepsy.

Study on the Recoil Operation of the Servomotor with PM Poles (PM형 제어용 Servo전동기의 Recoil동작에 관한 연구)

  • Se Hoon Chang
    • 전기의세계
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    • v.21 no.4
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    • pp.15-21
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    • 1972
  • For the conventional DC machine, the armature MMF is negligible compared with field MMF except when the machine is under heavy load or transient conditions. During the motor starting or reversal, the transient armature current and corresponding MMF effect the flux density of each pole in the machine magnetic circuit. However, the circuit flux density is restored to normal values by the field winding MMF after the transient armature current dies in an electromagnetic DC motor. Permanent magnet servomotor have no field windings about the circuit poles to restore circuit flux density through the demagnetized part of each pole after the transient armature MMF dies, and portions of the magnetic circuit stay permanently demagnetized. Thus the problem of stabilizing a magnet pole piece under the influence of the transient armature current need attentions. This work present the recoil operation of the servomotor with PM poles in conjunctions with the influence of the armature reaction effect. The development of an analytical and quantatative study is presented for predicting the regime of the recoil operation under this condition.

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Investigation on flutter mechanism of long-span bridges with 2d-3DOF method

  • Yang, Yongxin;Ge, Yaojun;Xiang, Haifan
    • Wind and Structures
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    • v.10 no.5
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    • pp.421-435
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    • 2007
  • A two-dimensional flutter analysis method (2d-3DOF method) was developed to simultaneously investigate the relationship between oscillation parameters and aerodynamic derivatives of three degrees of freedom, and to clarify the coupling effects of different degrees of freedom in flutter instability. With this method, the flutter mechanism of two typical bridge deck sections, box girder section and two-isolated-girder section, were numerically investigated, and both differences and common ground in these two typical flutter phenomena are summarized. Then the flutter stabilization effect and its mechanism for long-span bridges with box girders by using central-slotting were studied by experimental investigation of aerodynamic stability and theoretical analysis of stabilizing mechanism. Possible explanation of new findings in the evaluation trend of critical wind speed through central vent width is finally presented.

Influence of Elastic Constraints at Free End on Stability of Timoshenko Cantilever Beam Subjected to a Follower Force (종동력을 받는 Timoshenko 외팔보에서 자유단의 탄성구속이 안정성에 미치는 영향)

  • 윤한익;손종동;김현수
    • Journal of the Korean Society of Safety
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    • v.11 no.2
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    • pp.116-121
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    • 1996
  • On the stability of Timoshenko cantilever beam subjected to a follower force, the influence of the characteristics of elastic constraints at the free end Is studied. The equations of motion and boundary conditions of this nonconservative elastic system are estabilished by using the Hamilton's principle. Upon evaluation of the stability of this system, the effect of shear deformation and rotatory inertia is considered in calculation. Using cowper's formulae Timoshenko's shear coefficient K'are determined. From this imvestigation it is found that the constrain parameter have an appreciable stabilizing effect in this nonconservative system. Moreover, it is obvious that the small values of K'decrease the flutter load of this system.

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Antipruritic Effect of Black Colored Rice

  • Han, Sang-Jun;Trinh, Hien Trung;Hong, Seong-Sig;Ryu, Su-Noh;Kim, Dong-Hyun
    • Natural Product Sciences
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    • v.13 no.4
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    • pp.373-377
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    • 2007
  • Antiscratching behavioral effects of the water extract of two black colored rice (BCR) varieties [Oryza sativa L. cv. Heugjinjubyeo (HJ) and Josaengheugchalbyeo (JH)], major pigment of which is cyanindin 3-glucoside, were investigated. Orally administered BCRs' extracts exhibited potent inhibitory activity against scratching behaviors which were induced by compound 48/80 and histamine. The inhibitory effect of Josaengheugchalbyeo in vivo and in vitro were more potent than those of Heugjinjubyeo. These finding suggest that black colored rice, especially Josaengheugchalbyeo, may inhibit scratching behaviors and anaphylaxis reaction by stabilizing membrane.

Effect of pyrolysis temperature on the thermal energy storage performance of sesame plant biochar (참깨 바이오차의 열분해 온도가 열에너지 저장 성능에 미치는 영향 평가)

  • Soumen Mandal;Lee, Han-Seung
    • Proceedings of the Korean Institute of Building Construction Conference
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    • 2023.11a
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    • pp.65-66
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    • 2023
  • This study is aimed to understand the effect of pyrolysis temperature on the biochar synthesis for shape stabilizing the Lauric acid (LA). Three different temperatures (350, 500, and 650 ℃) have been chosen with a soaking time of 1h for synthesizing biochars form sesame plants (SP). The structural characterizations indicate the formation of amorphous biochar at 350 ℃ whereas, a stain of graphene formation has been observed for the biochar synthesized at 500 ℃. Formation of a substantial amount of graphene has been found for the sample, synthesized at 650 ℃. Energy storage performances of the PCMs which are shape stabilized by these three biochars have been discussed in this paper.

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Studies on the Enzyme-releasing Mechanism of Aminoglycosides from Pancreas (Aminoglycosides의 취효소 분비항진기전에 관한 연구)

  • Shim, Ho-Shik;Kim, Kyung-Hwan;Hong, Sa-Suk
    • The Korean Journal of Pharmacology
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    • v.19 no.1
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    • pp.71-76
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    • 1983
  • Aminoglycoside antibiotics are reported to enhance the amylase release from isolated slices of pancreas in vitro and the mode of action of aminoglycosides on amylase release is considered different from those of acetylcholine or cholecystokinin(CCK), i.e., electronmicroscopically intact zymogen granules are appeared in the lumen of pancreatic acini by treatment of aminoglycosides. It is known that atropine blocks the secretagogue effect of acetylcholine, and phenoxybenzamine is reported to block the effects of CCK or its analogue caerulein. Present study was undertaken to investigate the mode of action of aminoglycosides on the amylase release using atropine, phenoxybenzamine and propranolol as a membrane stabilizing agent in slices of chicken pancreas. The results are summarized as follows : 1) Streptomycin and kanamycin increased the amylase release significantly from slices of chicken pancreas. 2) The effect of streptomycin was inhibited by atropine but not by phenoxybenzamine or propranolol. 3) The amylase release by acetylcholine was blocked by atropine tut the effect of cholecystokinin octapeptide(CCK-8) was not influenced by atropine, phenoxybenzamine or propranolol. 4) Pretreatment of streptomycin enhanced the secretagogue effect of acetylcholine or CCK-8. From these results it is suggested that amylase releasing effects of aminoglycosides are mediated in part by cholinergic stimulation and in part by membrane alteration and these effects are enhanced by acetylcholine or cholecystokinin.

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Role of Calcium on Auxin-Induced Ethylene Production in Etiolated Mungbean(Vigna radiata W.) Hypocotyls (녹두(Vigna radiata W.) 하배축의 오옥신 유발 에틸렌 생성 과정에서 $Ca^{2+}$의 작용)

  • 문혜정
    • Journal of Plant Biology
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    • v.32 no.4
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    • pp.265-274
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    • 1989
  • The effect of Ca2+ on auxin-induced ehtylene production in etiolated mungbean (Vigna radiata W.) hypocotyls was studied. Auxin-induced ethylene production by mungbean seedlings which had been germinated in the presence of 5-10mM Ca2+ (High Ca2+ ; HC) is greater than that by seedlings which had been germinated in distilled water (Low Ca2+ ; LC). The effect of Ca2+ on auxin-induced ethylene production was greatly increased after 12hr of incubation period. The stimulation of auxin-induced ethylene production by Ca2+ was specific, since divalent cations, such as Mg2+ and Mn2+ did not enhance auxin-induced ethylene production. Calcium also promoted ethylene evoluation induced by methionine and 1-Aminocyclopropane-1-carboxylic acid(ACC). The effect of Ca2+ on auxin-induced ethylene production was not caused by increase in free IAA or ACC contents of hypocotyl tissue. Dimethyl sulfoxide and Triton X-100, that disrupts the emembranes, inhibited ethylene production to a greater extent in LC segments than in HC segments. Addition of Ca2+ to the incubation medium for LC segments resulted in enchancement of ethylene production probalby because the membrane integrity is supported under these conditions. Comparison of activity of Ethylene Forming Enzyme(EFE) in LC and HC hypocotyl segments indicated that the enzyme activity of HC was about 2 times higher than that of L.C. It is suggested that Ca2+ increases the activity of plasma membrane-bound EFE through its stabilizing effect onn the membrane, which in turn brings about promotion of ethylene production.

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Characteristics and Stability of the Color of the Cranberry Solution (크랜베리 수용액 색상의 특성 및 안정성)

  • 김진현;이재하;백창규
    • Journal of the Korean Society of Food Science and Nutrition
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    • v.32 no.6
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    • pp.806-811
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    • 2003
  • Effects of pH, temperature, light, sugars, organic acids, metal ions, ascorbic acid, thiamine nicotinic acid and pyridoxine on the stability of the color of the cranberry solution were investigated. The pH had marked influences on the color of the cranberry solution: i.e., the color of the cranberry solution was more intense at low pH. It showed characteristic bathochromic shift as the pH of the solution increased. The half-lives of olor value were 34 days at 37$^{\circ}C$, 91 mins at 9$0^{\circ}C$ and 29 mins at 12$0^{\circ}C$. Light gave an adverse effect to the stability of the color. The color degradation can be minimized by shielding the light from the cranberry solution. Among the sugars tested, fructose was the most deleterious followed by sucrose, galactose, maltose and glucose. Fumaric acid was found to be the most effective in stabilizing the color followed by citric acid, malic acid, acetic acid, while tartaric acid was found to be deleterious. Among the metal ions tested N $a^{+}$ and $Mg^{2+}$ were found to be effective in stabilizing the color, while M $n^{2+}$ was found to be the most deleterious followed by F $e^{2+}$, $K^{+}$ and $Ca^{2+}$. Ascorbic acid was found to be deleterious considerably followed by thiamine, while nicotinic acid and pyridoxine were found to be effective in stabilizing the color feebly.or feebly.

Applicability Test of Various Stabilizers for Heavy Metals Contaminated Soil from Smelter Area (제련소 주변 오염토양의 중금속 안정화를 위한 다양한 안정화제의 적용성 연구)

  • Jeon, Jonwon;Bae, Bumhan;Kim, Younghun
    • Journal of the Korean GEO-environmental Society
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    • v.11 no.11
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    • pp.63-75
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    • 2010
  • There are several remediation technologies for heavy metal contaminated soils but increasing cost limits the application of the technology if the contaminated area is large. Therefore, stabilization, which blocks the release of heavy metals or makes slow the release, is one of the applicable technology for the heavy metal contaminated soil. Current study is an applicability test for a smelter area with various stabilizer such as magnetite, hematite, zeolite-A, zeolite-X, zeolite-Y, zinc oxide, calcium oxide, carbon trioxide, manganese oxide, manganese dioxide, fish bone, sodium phosphate. The soil contaminated with arsenic, lead, copper, nickel, and zinc could not be stabilized only one stabilizer which is known to have stability for certain metal. Many of the stabilizer works for a few metal but not all of the heavy metal. In several cases, stabilizers increase the release of the other metals while they stabilize some metals. In general, the stabilizing efficiency was increased with time. For Ni, Pb, calcium oxide, carbon trioxide, manganese oxide had good stabilizing effect in water extractable portion. For Cu, manganese oxide, zeolite showed good results especially in the exchangeable portion of the sequential extraction. For As, magnetite had good ability but most of the metal oxide which showed good result for other heavy metals increased with the release of As. Current study suggest that multiple stabilizers are needed for the contaminated soil and dose of the stabilizer and stabilizing time should be carefully considered for the soil contaminated with various metals.