• Journal of Microbiology and Biotechnology
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• v.11 no.4
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• pp.656-662
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• 2001

Angiogenesis is known as a crucial process in the growth and spreading of tumor cells. Accordingly, the effective inhibition of this process would appear to be a promising way to cure angiogenesis-related diseases, including cancer. This study demonstrates that acalycixenolide E (AX-E) from the marine organism Acalycigorgia inermis exhibits a potent anti-angiogenic activity both in vitro and in vivo. AX-E inhibits the bFGF-induced proliferation of HUVECs in a dose dependent manner, along with the bFGF-induced migration, invasion, and tube formation of HUVECs. Moreover, AX-E potently inhibits the in vivo neovascularization of the chorioallantoic membranes (CAMs) of growing chick embryos. interestingly, AX-E suppresses the expression of metalloproteases 2 and 9, yet shows no effect on their activities. The novel chemical structure and potent anti-angiogenic activity of AX-E will be of great value in elucidating the molecular mechanism of angiogenesis as well as in the development of a novel anti-angiogenic drug.

• 한국연소학회:학술대회논문집
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• 2005.10a
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• pp.320-327
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• 2005

An experimental study was performed to investigate the effects of partially premixing, varying the equivalence ratios from $1.36{\sim}{\infty}$, and swirlers with swirl numbers of 0, 0.28, 0.64, and 1.32, on the characteristic of radical ($OH^{\ast}$, $CH^{\ast}$, and $C_2^{\ast}$) and pollutant emission in partially premixed swirling flames. The signal from the electronically excited state of $OH^{\ast}$, $CH^{\ast}$, and $C_2^{\ast}$ was detected through a band pass filter with a photo multiplier tube, and flow fields images were detected through a schlieren system. The results demonstrated that the flame height decreases and jet spreading angle increase with increasing a swirl number. The more momentum ratio and swirl number increase, the more decrease flame height, and the generation of sooting flame is promoted.

• Journal of Chest Surgery
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• v.20 no.2
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• pp.348-352
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• 1987

A 51 year-old male was admitted with the chief complaints of swallowing difficulty and pain on neck and upper chest for 2 months prior to admission: He was taken biopsy under esophagoscopy, and the result was squamous cell carcinoma. Preoperatively we studied the esophagogram and chest CT. On these, we found the main appreciable mass at midesophagus easily. But, we missed the upper cervical unexpected mass. So we performed the esophagectomy and lymph node dissection from upper clavicle level to the esophagogastric junction by thoracic approach as wide as possible, and cervical esophagostomy and feeding gastrostomy also. At that evening we reviewed the studied films in detail, and we found another mass lesion at C4-C6 level of cervical esophagus. We performed the 2nd operation e.g. cervical esophagectomy on next morning without hesitation. Between these two masses, there was almostly normally looking skip area grossly. The squamous cell carcinoma of the esophagus could be multicentric in character and may have skip area. But, we heard little reports until now. The two masses could be different in origin or be same probably by submucosal spreading. Anyway, it was an alarming case to the surgeon not to neglect the another possible lesions in squamous cell type. Postoperative course was uneventful, he took G-tube feeding with no problems on 7th postoperative day. Now he took the postoperative irradiation at out patient department.

• Journal of the Korean Society of Manufacturing Process Engineers
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• v.14 no.1
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• pp.29-35
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• 2015

In this study, a FEM analysis is undertaken of a rubber sleeve which is mounted onto a spreading mandrel so as to avoid marking the first wrappings of coils (known as the 'end-mark'), as occasionally occurs when a concentrated load is placed on the edge of a steel sheet, significantly reducing its quality. A commercial numerical package, ANSYS, was utilized to analyze the structural behavior of the rubber sleeve. In general, the strain of the sleeve increases as the thickness of the rubber layer (H) covering the tubes increases, thus also increasing the surface of the sleeve for a constant boundary condition, and decreasing the pitch (P) between each tube, resulting in an increase in the strain on the surface of the sleeve for all rubber thickness conditions tested here. In a comparison of two different materials, rubber and urethane, when H=3 mm and P=1.1D, the maximum total deformations in these cases are 0.12669 mm and 0.086623 mm, respectively.

• Proceedings of the KSME Conference
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• 2000.04b
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• pp.520-524
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• 2000

A ejector system is one of the fluid machinery, which has been mainly used as an exhaust pump or a vacuum pump. The ejector system has often been pointed out to have only a limited efficiency because it is driven by pure shear action and the mixing action between primary and secondary streams. In the present work, numerical simulations were conducted to investigate the effects of the geometry and the mass flow ratio of supersonic ejector-diffuser systems on their mixing performance. A fully implicit finite volume scheme was applied to solve the axisymmetric Navier-Stokes equations, and the standard ${\kappa}-{\varepsilon}$ turbulence model was used to close the governing equations. The flow fields of the supersonic ejector-diffuser systems were investigated by changing the ejector throat area ratio and the mass flow ratio. The existence of the second throat strongly affected the shock wave structure inside the mixing tube as well as the spreading of the under-expanded jet discharging from the primary nozzle, and served to enhance the mixing performance.

• Analyses & Alternatives
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• v.8 no.2
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• pp.5-30
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• 2024

The purpose of this paper is to study the concept of public interest in broadcasting, which has been approached only from a policy or legislative perspective in Korea, through analysis of the program content itself. To this end, this study focuses on French broadcasting, which has a long history of public service, has learned the concept of 'public interest' during its long growth process, and has specifically put this concept into practice through program production. Analysis of French TV programs that have been broadcast over the past 10 years categorizes the concept of public interest that French broadcasting has embodied into the following three categories. The first is the characteristic of 'freedom of speech: 'participation' and 'generality' in the public sphere' shown by discussion programs or talk shows. The second is the characteristic of 'transmission of cultural identity', which is shown even in entertainment programs. The third is the characteristic of 'social capital: spreading the value of social solidarity' shown in documentary or discussion programs. In addition, we examine how French broadcasting is implementing public interest at a time when digital media such as YouTube or Instagram are becoming the center of the media environment, and a digital public social media called 'Culture Prime' created by public institutions.

• The Journal of the Convergence on Culture Technology
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• v.8 no.5
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• pp.459-468
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• 2022

This study searched and analyzed news and information on the Korea-U.S. Summit to explore which political agenda is spreading among Korean newspapers and social media. The result of the analysis revealed that, on the one hand, the conservative-leaning newspaper, Chosunilbo, covered the unresolved issue between two countries. The principal source of news was the opposition party. On the other hand, the progressive-leaning newspaper, Kyunghany Sinmun, highlighted President Moon's visit to the United States and described the visit to the United States as an achievement. In this paper, the principal source of news is the ruling party. Both conservative and the progressive newspapers did not present a negative view of the United States. In the case of Chosunilbo, it mentioned that foreign policy priority of President Biden is human rights in North Korea. If the two countries do not solve this issue, the relationship between Korea and the United States will not develop further. Second, I searched YouTube videos about the Korea-U.S. summit and conducted a network analysis to understand the influence of YouTube videos and explore their relationship the each other. The results of the analysis revealed that the 10 most influential videos portrayed the Moon government positively. These videos held the achievement of the visit to the United States in highly esteem and framed it positively, similarly to the progressive newspaper.

• Korean Journal of Veterinary Service
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• v.33 no.3
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• pp.249-254
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• 2010

Deer can be one of the susceptible animals to bovine infectious diseases, and thus, may play a role either as a reservoir or amplifier host for spreading the diseases to other species such as cattle and goat. This study was conducted to determine the serum antibodies to bacterial infectious diseases for brucellosis, tuberculosis (TB), paratuberculosis (Johne's disease) in deer. Serum samples were randomly collected from 78 deer from 31 farms at Jeonbuk province, and 7 wild water deer from Jeonbuk wild animal treatment center during 2005 to 2007, respectively. Four farm deer (5.1%) showed antibodies to tuberculosis using Antigen Rapid Bovine TB Ab Test Kit. One elk (1.3%) and one wild water deer had antibodies for paratuberculosis. Antibody against Brucellosis was not detected in tube agglutination test (TAT) and enzyme-linked immunosorbent assay (ELISA). These data suggest that caution should be applied to inspection of velvet, deer blood and meat for human consumption from deer because of zoonotic bacterial diseases in deer. In addition, farmed deer can be a transmissible host for zoonotic disease to diary or raising farm.

• Journal of Digital Convergence
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• v.11 no.3
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• pp.95-100
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• 2013

K-POP is getting population at the all over the world. K-POP is based on the hook song that made using repetitive lyrics and melody. The characteristics of the music is a bit simple and cheerful rhythm and melody easy to sing along, interesting lyrics and great dance skills. K-POP is spreading to various countries via various social networking services such as YouTube, Facebook, Twitter. K-POP dominated by the digital music market, showed a growing tendency to shorten the length of music, to create a music that can give a strong impression. And 60 second pre-listening function increased music used the chorus in the first part. But it was generated the result that made obscures the configuration of the music and the meaning of the lyrics. In this paper, we study the characteristics of K-POP music and will present three directions of the hook song music production. Finally, we compared to Kangnamstyle of Psy using the proposed three standards.

• Economic and Environmental Geology
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• v.29 no.6
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• pp.713-724
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• 1996

The time-series resident solute concentrations, monitored at two field plots using the automated 144-channel TDR system by Kim (this issue), are used to investigate the dominant transport mechanism at field scale. Two models, based on contradictory assumptions for describing the solute transport in the vadose zone, are fitted to the measured mean breakthrough curves (BTCs): the deterministic one-dimensional convection-dispersion model (CDE) and the stochastic-convective lognormal transfer function model (CLT). In addition, moment analysis has been performed using the probability density functions (pdfs) of the travel time of resident concentration. Results of moment analysis have shown that the first and second time moments of resident pdf are larger than those of flux pdf. Based on the time moments, expressed in function of model parameters, variance and dispersion of resident solute travel times are derived. The relationship between variance or dispersion of solute travel time and depth has been found to be identical for both the time-series flux and resident concentrations. Based on these relationships, the two models have been tested. However, due to the significant variations of transport properties across depth, the test has led to unreliable results. Consequently, the model performance has been evaluated based on predictability of the time-series resident BTCs at other depths after calibration at the first depth. The evaluation of model predictability has resulted in a clear conclusion that for both experimental sites the CLT model gives more accurate prediction than the CDE model. This suggests that solute transport at natural field soils is more likely governed by a stream tube model concept with correlated flow than a complete mixing model. Poor prediction of CDE model is attributed to the underestimation of solute spreading and thus resulting in an overprediction of peak concentration.