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ORAL PEMPHIGUS VULGARIS: A CASE REPORT (구강내 발생한 심상성 천포창 환자의 치험례)

  • Kim, Il-Kyu;Choi, Jin-Ung;Yang, Jung-Eun;Jang, Jae-Won;Sasikala, Balaraman;Kim, Lucia
    • Maxillofacial Plastic and Reconstructive Surgery
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    • v.31 no.5
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    • pp.414-418
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    • 2009
  • Pemphigus vulgaris is a chronic autoimmune intraepithelial blistering disease with oral mucosal manifestations that very often precede the skin lesions. The vesicles or bullae are produced by an acantholytic process, detachment of differentiating keratinocytes from one another in the epithelial stratum spino sum or spinous cell layer. The pathogenesis of this disease is initially manifested by IgG(mainly) binding to desmosome(desmoglein 3 or 1) in the intercellular spaces of epithelium. This autoantibody binding caused the release of a plasminogen activator(a proteolytic enzyme) from keratinocytes. This ultimately results in cell to cell separation. The mainstay therapy of pemphigus vulgaris is systemic corticosteroids and immunosuppressive agents to eliminate the pathogenic autoantibodies from circulation. A 41-year old woman presented with a 1.5 year history of oral ulceration. There were no lesions on the skin or other mucosal sites. Histology and immunostaining were consistent with pemphigus vulgaris. Control of oral ulceration and normal oral function were achieved after systemic corticosteroids and immunosuppressive agents were instituted.

First Record of Two Perciform Fishes, Chelidoperca pleurospilus (Serranidae) and Parapercis muronis (Pinguipedidae) from Korea (한국산 농어목 어류 2 미기록종, Chelidoperca pleurospilus 및 Parapercis muronis)

  • Park, Jeong-Ho;Kim, Jin Koo;Choi, Jung Hwa;Chang, Dae Soo;Park, Jong Hwa
    • Korean Journal of Ichthyology
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    • v.19 no.3
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    • pp.246-252
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    • 2007
  • Two specimens (56.3~61.1 mm SL) of the serranid fish, Chelidoperca pleurospilus and 21 specimens (34.0~93.6 mm SL) of the pinguipedid fish, Parapercis muronis were collected around Jeju Island, southern Korea. C. pleurospilus is characterized by having five dark blotches along lateral line, truncated caudal fin, and scaleless interorbital space. P. muronis is characterized by having five oblique dark bands on body side, five spines on dorsal fin, and no notch between spinous and soft-rayed portions of dorsal fin. We describe these specimens as the first record from Korea, and propose the new Korean name, "Byeol-gak-si-dom" for the former and "Da-seosjul-yang-dong-mi-ri" for the latter.

The Effect of Forward Head Posture Correctional Device During Computer Work (컴퓨터 작업 시 전방머리자세 교정장치의 효과)

  • Yi, Chung-Hwi;Yoo, Won-Gyu;Kim, Min-Hee
    • Physical Therapy Korea
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    • v.13 no.1
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    • pp.9-15
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    • 2006
  • Work-related musculoskeletal disorder has been associated with long hours of computer work and prolonged periods of static posture. In clinical settings, postural correction is a common treatment approach for individuals with neck, shoulder, and back pain. This study was designed to identify the effect of Forward Head Posture Correctional Device during computer work. Twelve healthy adults (mean age, 27.4 yrs; mean height, 165.0cm mean weight, 65.8 kg) participated in the study. They had no medical history of neurological or surgical problems with their upper extremity. The subjects were asked to perform Head Forward Posture under the guidance of physical therapists and the measured angles were analyzed using a 3-D motion analysis system. Markers were placed on the C7 spinous process, tragus of the ear and forward head angle was between the line from the tragus to the C7 line and the Y-axis at the C7. The statistical significance of difference between, "without" and "with" correctional device was tested by paired t-test. A level of significance was set at ${\alpha}$=.05. In comparison of the computer work between "without" and "with" correctional device, Forward Head Angle was showed significant difference (p<.05). In conclusion, the range of Forward Head Angle was significantly decreased during computer work with the correctional device. Further research is needed to understand the nature of motor control problems in deep muscles in patients with neck, shoulder, and back pain.

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Immediate Effects of a Postural Correction Garment Designed for Postural Kyphosis on Adolescents With Thoracic Hyperkyphosis: A Pilot Study

  • Kim, Ki-Song;Choi, Jung-Hwa;Park, Yoon-Ghil
    • Physical Therapy Korea
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    • v.18 no.4
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    • pp.43-50
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    • 2011
  • The purpose of this study was to investigate the changes in the flexicurve kyphosis index (KI), the flexicurve lordosis index (LI) and the distance from the inferior angle of the scapula to the nearest vertebral spinous process (DS), as a dependent variable of scapular protraction, after applying of adolescents with thoracic hyperkyphosis using three different garments. A repeated measures design was used. Ten adolescents ($15.8{\pm}1.0$ years) with thoracic hyperkyphosis ($40.1{\pm}3.7$ Cobb angle) were recruited from a university hospital. A flexicurve ruler was used to measure KI and LI and a scoliometer was used to measure DS under three different conditions: wearing-a hospital garment (HG), wearing-a sham garment (SG), and wearing-an experimental garment (EG). KI under EG condition was significantly decreased compared with that wearing the HG. However, there was no significant difference between wearing the SG and HG. LI when wearing the EG was significantly increased compared with that when wearing HG. However, there was no significant difference under SG and HG conditions. DS when wearing the EG was significantly decreased compared with wearing HG. However, there was no significant difference between the SG and HG. The results of this study show that the EG was effective in decreasing KI, but not effective in decreasing LI. Hence, the effect of the EG for correcting sagittal spine angle in adolescents with thoracic hyperkyphosis is still debatable. However, since we showed that DS decreases in the EG, this method could be applied in correcting the scapular protraction.

A Lower T1 Slope as a Predictor of Subsidence in Anterior Cervical Discectomy and Fusion with Stand-Alone Cages

  • Lee, Su Hun;Lee, Jun Seok;Sung, Soon Ki;Son, Dong Wuk;Lee, Sang Weon;Song, Geun Sung
    • Journal of Korean Neurosurgical Society
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    • v.60 no.5
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    • pp.567-576
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    • 2017
  • Objective : Preoperative parameters including the T1 slope (T1S) and C2-C7 sagittal vertical axis (SVA) have been recognized as predictors of kyphosis after laminoplasty, which is accompanied by posterior neck muscle damage. The importance of preoperative parameters has been under-estimated in anterior cervical discectomy and fusion (ACDF) because there is no posterior neck muscle damage. We aimed to determine whether postoperative subsidence and pseudarthrosis could be predicted according to specific parameters on preoperative plain radiographs. Methods : We retrospectively analyzed 41 consecutive patients (male : female, 22 : 19; mean age, $51.15{\pm}9.25years$) who underwent ACDF with a stand-alone polyether-ether-ketone (PEEK) cage (>1 year follow-up). Parameters including SVA, T1S, segmental angle and range of motion (ROM), C2-C7 cervical angle and ROM, and segmental inter-spinous distance were measured on preoperative plain radiographs. Risk factors of subsidence and pseudarthrosis were determined using multivariate logistic regression. Results : Fifty-five segments (27 single-segment and 14 two-segment fusions) were included. The subsidence and pseudarthrosis rates based on the number of segments were 36.4% and 29.1%, respectively. Demographic data and fusion level were unrelated to subsidence. A greater T1S was associated with a lower risk of subsidence (p=0.017, odds ratio=0.206). A cutoff value of T1S<$28^{\circ}$ significantly predicted subsidence (sensitivity : 70%, specificity : 68.6%). There were no preoperative predictors of pseudarthrosis except old age. Conclusion : A lower T1S (T1S<$28^{\circ}$) could be a risk factor of subsidence following ACDF. Surgeons need to be aware of this risk factor and should consider various supportive procedures to reduce the subsidence rates for such cases.

Novel Hybrid Hydroxyapatite Spacers Ensure Sufficient Bone Bonding in Cervical Laminoplasty

  • Tanaka, Nobuhiro;Nakanishi, Kazuyoshi;Kamei, Naosuke;Nakamae, Toshio;Kotaka, Shinji;Fujimoto, Yoshinori;Ochi, Mitsuo;Adachi, Nobuo
    • Asian Spine Journal
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    • v.12 no.6
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    • pp.1078-1084
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    • 2018
  • Study Design: Prospective observational study. Purpose: This prospective analysis aimed to evaluate the efficacy and bone-bonding rate of hybrid hydroxyapatite (HA) spacers in expansive laminoplasty. Overview of Literature: Various types of spacers or plates have been developed for expansive laminoplasty. Methods: Expansive open-door laminoplasty was performed in 146 patients with cervical myelopathy; 450 hybrid HA spacers and 41 autogenous bone spacers harvested from the spinous processes were grafted into the opened side of each lamina. The patients were followed up using computed tomography (CT), and their bone-bonding rates for hybrid HA and autogenous spacers, bone-fusion rates of the hinges of the laminae, and complications associated with the implants were then examined. Results: Clinical symptoms significantly improved in all patients, and no major complications related to the procedure were noted. The hybrid HA spacers exhibited sufficient bone bonding on postoperative CT. The hinges completely fused in over 95% patients within 1 year of the procedure. Only 4 spacers (0.9%) developed lamina sinking, and most expanded laminae maintained their positions without sinking or floating throughout the follow-up period. Conclusions: Hybrid HA spacers contributed to high bone-fusion rates of the spacers and hinges of the laminae, and no complications were associated with their use. Cervical laminoplasty with these spacers is safe and simple, and it yields sufficient fixation strength while ensuring sufficient bone bonding during the immediate postoperative period.

The Effects of the Crocodile Breathing Exercise on the Muscle Activity of the Erector Spinae Muscle in Patients with Low Back Pain (크로커다일호흡 운동이 요통 환자들의 척주세움근 근활성도에 미치는 영향)

  • Cho, Yong-Ho
    • PNF and Movement
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    • v.17 no.2
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    • pp.321-327
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    • 2019
  • Purpose: This study aimed to investigate the effects of the crocodile breathing exercise on the muscle activity of the erector spinae muscle in patients with low back pain. Methods: The study subjects included 36 patients with low back pain. The patients were divided equally into the experimental group (EG) and the control group (CG). The EG performed the crocodile breathing exercise, and the CG performed a chest expansion breathing exercise. The intervention was conducted for 10 minutes each day for a total of eight weeks. Measurements of muscle activity were conducted using an MP150 system. An electrode was attached 2 cm to the side of the spinous process at the L4-L5 level. The muscle activity value used was %MVIC, and the statistical significance was 0.05. The paired t-test was the statistical method used to determine the pre- and post-average value of each breathing exercise, while the independent t-test was used to assess the delta value of muscle activity in the pre-post test. Results: Inspiration muscle activity showed a significant increase in both the EG and the CG, while expiration muscle activity decreased significantly in both groups. The delta value of muscle activity showed a significant difference in inspiration (p<0.05), but for expiration, there was no significant difference in muscle activity (p>0.05). Conclusion: This study suggests that crocodile breathing is a good method for improving muscle activity in patients with low back pain.

Immediate Effect of Serratus Posterior Inferior Muscle Direction Taping on Thoracolumbar Junction Rotation Angle During One Arm Lifting in the Quadruped Position

  • Kim, Nu-ri;Ahn, Sun-hee;Gwak, Gyeong-tae;Yoo, Hwa-ik;Kwon, Oh-yun
    • Physical Therapy Korea
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    • v.28 no.3
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    • pp.227-234
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    • 2021
  • Background: The serratus posterior inferior (SPI) muscle originates from the spinous process of T11-L2 and inserts at the lower border of the 9-12th ribs. This muscle is involved in thoracolumbar rotation and stability. Several positions can be used to improve trunk stability; the quadruped position is a good position for easily maintaining a neutral spine. In particular, during one arm lifting, various muscles act to maintain a neutral trunk position, and the SPI is one of these muscles. If trunk stability is weakened, uncontrolled trunk rotation may occur at this time. Tape can be used to increase trunk stability. There have been no studies on the effect of taping applied to the SPI muscle on thoracolumbar junction (TLJ) stability. Objects: This study compared the TLJ rotation angle between three different conditions (without taping, transverse taping, and SPI muscle direction taping). Methods: Thirty subjects were recruited to the study (18 males and 12 females). The TLJ rotation angle was measured during one arm lifting in a quadruped position (ALQP). Two taping methods (transverse and SPI muscle direction taping) were applied, and the TLJ rotation angle was measured in the same movement. Results: SPI muscle direction taping significantly reduced TLJ rotation compared to that without taping (p < 0.001) and with transverse taping (p < 0.001). There was a significant difference in the TLJ rotation angle between transverse taping and SPI muscle direction taping (p < 0.017). Conclusion: SPI muscle direction taping reduces the TLJ rotation angle during ALQP. Therefore, SPI muscle direction taping is one method to improve TLJ stability and reduce uncontrolled TLJ rotation during ALQP.

Relationship between needle depth for lumbar transforaminal epidural injection and patients' height and weight using magnetic resonance imaging

  • John, Hyunji;Sohn, Kyomin;Kim, Jae Hun
    • The Korean Journal of Pain
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    • v.35 no.3
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    • pp.345-352
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    • 2022
  • Background: Optimal needle depth in transforaminal epidural injection (TFEI) is determined by body measurements and is influenced by the needle entry angle. Physician can choose the appropriate needle length and perform the procedure more effectively if depth is predicted in advance. Methods: This retrospective study included patients with lumbosacral pain from a single university hospital. The skin depth from the target point was measured using magnetic resonance imaging transverse images. The depth was measured bilaterally for L4 and L5 TFEIs at 15°, 20°, and 25° oblique angles from the spinous process. Results: A total of 4,632 measurements of 386 patients were included. The lengths of the left and right TFEI at the same level and oblique angle were assessed, and no statistical differences were identified. Therefore, linear regression analysis was performed for bilateral L4 and L5 TFEIs. The R-squared values of height and weight combined were higher than the height, weight, and body mass index (BMI). The following equation was established: Depth (mm) = a - b (height, cm) + c (weight, kg). Based on the equation, maximal BMI capable with a 23G, 3.5-inch, Quincke-type point spinal needle was presented for three different angles (15°, 20°, and 25°) at lumbar levels L4 and L5. Conclusions: The maximal BMI that derived from the formulated equation is listed on the table, which can help in preparations for morbid obesity. If a patient has bigger BMI than the one in the table, the clinician should prepare longer needle than the usual spinal needle.

The effect of Modified Sacroiliac Joint Taping on Back pain_A case report (변형된 엉치엉덩관절 테이핑의 요통 효과 사례보고)

  • Il-Young Cho
    • Journal of Digital Policy
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    • v.3 no.1
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    • pp.21-25
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    • 2024
  • This is a case study that sought to consider whether taping, which focuses on instability of the sacroiliac joint, is a potential intervention method that may be helpful for low back pain. In the case of a 58-year-old participant, we summarized the notable results from a taping training session that a man with a history of back surgery due to disc herniation and stenosis participated in to reduce ongoing pain. As an intervention method, tape was applied between the 2nd and 4th sacrum on both sides from the spinous tuberosity. It was stretched to a tension of 80% and attached past the sacroiliac joint, and then the ends were raised at about 45° on both sides and attached toward the gluteus medius muscle. Then, along the erector spinae muscle from the iliac crest. Bilateral taping up to the level of the 10th rib was applied. Through this intervention, positive case results were observed from both VAS and ODI test tools, with VAS recorded as 5 to 0 and disability index recorded as 13 to 0, respectively.