• Journal of the Korean Society of Visualization
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• v.15 no.1
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• pp.32-40
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• 2017

Interaction between fluid and a rigid object is frequently observed in everyday life. However, it is difficult to simulate their interaction as the medium and the object have different representations. One of the challenging issues arises especially in handling deformation of the object visually as well as rendering haptic feedback. In this paper, we propose a real-time simulation technique for multimodal interaction between particle-based fluids and soluble solids. We have developed the dissolution behavior model of solids, which is discretized based on the idea of smoothed particle hydrodynamics, and the changes in physical properties accompanying dissolution is immediately reflected to the object. The user is allowed to intervene in the simulation environment anytime by manipulating the solid object, where both visual and haptic feedback are delivered to the user on the fly. For immersive visualization, we also adopt the screen space fluid rendering technique which can balance realism and performance.

• Archives of Pharmacal Research
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• v.29 no.11
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• pp.1049-1054
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• 2006

Activation of Sphingosine kinase (Sphk) increases a bioactive lipid, sphingosine 1-phosphate (S1P) and has been observed in a variety of cancer cells. Therefore, inhibition of Sphk activity was an important target for the development of anticancer drugs. As a searching tool for Sphk inhibitor, we developed fluorescent Sphk activity assay combined with high performance liquid chromatography (HPLC). Previously we established murine teraticarcinoma mutant F9-12 cells which lack S1P lyase and stably express Sphk1. By using F9-12 cells, optimal assay conditions were established as follows; $100\;{\mu}M\;of\;C_{17}-Sph\;and\;30\;{\mu}g$ protein of F9-12 cells lysate in 20 min. Sphingosine analog $C_{17}-Sph$ was efficiently phosphorylated by Sphk activity ($K_{m}:67.08\;{\mu}M,\;V_{max}\;:1507.5\;pmol/min/mg$). New product $C_{17}-S1P$ was separated from S1P in reversed-phase HPLC. In optimized conditions, 300 nM of phorbol 12-myristate 13-acetate (PMA) increased Sphk activity approximately twice while $20\;{\mu}M$ of N,N-dimethylsphingosine (DMS) reduced 70% of Sphk activity in F9-12 cells lysate. In conclusion, we established non-radioactive but convenient Sphk assay system by using HPLC and F9-12 cells.

• Journal of the Korean Geosynthetics Society
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• v.19 no.3
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• pp.1-8
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• 2020

In this study, numerical analysis of debris flow was performed using the SPH (Smoothed Particle Hydrodynamics) technique to analyze the mechanism of debris flow, and the applicability of soil parameters was verified by comparison with previous studies. In addition, after performing aerial photographic survey using a drone, a topographic model was created based on this survey to check the applicability of the site to the valley part of Jagul Mountain basin. And after numerical analysis of debris flow was performed using NFLOW, and the result was compared and analyzed with the existing satellite image based method. As a result of this study, the numerical analysis method using drone image and NFLOW was found to have a higher applicability to predicting the impact of debris flow, because it can reflect the actual topography better than the existing method based on satellite imagery. Therefore, it is considered that this study can be used as basic data to establish the preventive measures for debris flow such as location selection of the eruption control dam.

• Advances in aircraft and spacecraft science
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• v.1 no.2
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• pp.233-251
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• 2014

Each aircraft have to be certified for a specified level of impact energy, for assuring the capability of a safe flight and landing after the impact against a bird at cruise speed. The aim of this research work was to define a scientific and methodological approach to the study of the birdstrike phenomenon against several windshield geometries. A series of numerical simulations have been performed using the explicit finite element solver code LS-Dyna, in order to estimate the windshield-surround structure capability to absorb the bird impact energy, safely and efficiently, according to EASA Certification Specifications 25.631 (2011). The research considers the results obtained about a parametric numerical analysis of a simplified, but realistic, square flat windshield model, as reported in the last work (Grimaldi et al. 2013), where this model was subjected to the impact of a 1.8 kg bird model at 155 m/s to estimate the sensitivity of the target geometry, the impact angle, and the plate curvature on the impact response of the windshield structure. Then on the basis of these results in this paper the topic is focused about the development of a numerical simulation on a complete aircraft windshield-surround model with an innovative configuration. Both simulations have used a FE-SPH coupled approach for the fluid-structure interaction. The main achievement of this research has been the collection of analysis and results obtained on both simplified realistic and complete model analysis, addressed to approach with gained confidence the birdstrike problem. Guidelines for setting up a certification test, together with a design proposal for a test article are an important result of such simulations.

• Nuclear Engineering and Technology
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• v.48 no.1
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• pp.246-258
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• 2016

The shield building of AP1000 was designed to protect the steel containment vessel of the nuclear reactor. Therefore, the safety and integrity must be ensured during the plant life in any conditions such as an earthquake. The aim of this paper is to study the effect of water in the water tank on the response of the AP1000 shield building when subjected to three-dimensional seismic ground acceleration. The smoothed particle hydrodynamics method (SPH) and finite element method (FEM) coupling method is used to numerically simulate the fluid and structure interaction (FSI) between water in the water tank and the AP1000 shield building. Then the grid convergence of FEM and SPH for the AP1000 shield building is analyzed. Next the modal analysis of the AP1000 shield building with various water levels (WLs) in the water tank is taken. Meanwhile, the pressure due to sloshing and oscillation of the water in the gravity drain water tank is studied. The influences of the height of water in the water tank on the time history of acceleration of the AP1000 shield building are discussed, as well as the distributions of amplification, acceleration, displacement, and stresses of the AP1000 shield building. Research on the relationship between the WLs in the water tank and the response spectrums of the structure are also taken. The results show that the high WL in the water tank can limit the vibration of the AP1000 shield building and can more efficiently dissipate the kinetic energy of the AP1000 shield building by fluid-structure interaction.

• Proceedings of the Korean Information Science Society Conference
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• 2003.10c
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• pp.499-501
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• 2003

무선링크에서 TCP의 성능을 향상시키기 위한 연구들이 많이 수행되었으며, 다양한 기법들이 제안되고 있다. 하지만, 대부분의 연구들이 TCP 송신측이 무선링크에서의 패킷 손실을 혼잡으로 오해하는 문제를 해결하는데 초점을 맞추고 있다. 또한 이러한 연구들은 대부분 시뮬레이션을 통해 측정되고 검증된 결과들이기 때문에 실제 환경을 반영하는 데는 완전하지 않다. 본 논문에서는 SKT의 CDMA2000­1x 상용 망에서 삼성전자의 SPH­A500 단말기를 이용하여 TCP와 UDP의 성능을 측정하였다. 본 연구에서는 CDMA2000­1x의 정확한 특성을 측정하고 분석하여. 무선링크에서의 delay spike에 의한 불필요한 timeout을 방지하고, 병목 링크에서의 큐 길이를 안정되게 유지하는 방법을 고안하고자 한다. 이를 위해 본 논문에서는 측정 과정에서 분석된 CDMA2000­1x의 특성을 정리한다.

• Journal of Korean Ophthalmic Optics Society
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• v.15 no.3
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• pp.219-225
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• 2010

Purpose: Usefulness in predicting the power of spherical rigid gas-pearmeable (RGP) lenses prescription using dioptric power matrices and arithmetic calculations was evaluated in this study. Noncycloplegic refractive errors and over-refractions were performed on 110 eyes of 55 subjects (36 males and 19 females, aged $24.60{\pm}1.55$years) in twenties objectively with an auto-refractometer (with keratometer) and subjectively. Tear lenses were calculated from keratometric readings and base curves of RGP lenses, and the power of RGP lenses were computed by a dioptric power matrix and an arithmetic calculation from the manifest refraction and the tear lens, and were compared with those by over-refractions in terms of spherical (Sph), spherical quivalent (SE) and astigmatic power. Results: The mean difference (MD) and 95% limits of agreement (LOA=$MD{\pm}1.96SD$) were better for SE (0.26D, $0.26{\pm}0.70D$) than for Sph (0.61D, $0.61{\pm}0.86D$). The mean difference and agreement of the cylindrical power between matrix and arithmetic calculation (-0.13D, $-0.13{\pm}0.53D$) were better than between the others (-0.24D, $0.24{\pm}0.84D$ between matrix and over-refraction; -0.12D, $0.12{\pm}1.00D$ between arithmetic calculation and over-refraction). The fitness of spherical RGP lenses were 54.5% for matrix, 66.4% for arithmetic calculation and 91.8% for over-refraction. Arithmetic calculation was close to the over-refraction. Conclusions: In predicting indications and powers of spherical RGP lens fitting, although there are the differences of axis between total (spectacle) astigmatism and corneal astigmatism, Spherical equivalent using an arithmetic calculation provides a more useful application than using a dioptric power matrix.

• The Bulletin of The Korean Astronomical Society
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• v.37 no.1
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• pp.43.1-43.1
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• 2012

We have performed our first cosmological hydrodynamic simulation using the recently developed SPH+GOPTM code that includes radiative cooling/heating, star formation, and supernova feedback. Here we present preliminary results from the simulation $3.4{\times}10^4M_{\odot}$, thus sub-galactic structures, such as satellite galaxies and globular clusters around a host galaxy, can be resolved with more than hundred particles. We follow formation and evolution of the sub-galactic structures in view of their star formation history, merging/accretion rate, and origins.

• The Bulletin of The Korean Astronomical Society
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• v.38 no.2
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• pp.40.1-40.1
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• 2013

We perform a set of N-body/SPH simulations of galaxy interactions between early- and late-type galaxies with the mass ratio of 2 to 1. We show that mass transfer during a fly by interaction (the closest approach distance ~50kpc) can cause the morphology transformation of an early-type galaxy to a late type. In our simulations, we vary the orbital parameters of the interactions and the cold gas fraction of the late-type galaxy to compare how the morphology transformation is affected by the amount of mass transfer and orbital angular momentum of cold gas accreted to the early type. We also include hot halo gas in the galaxy models and show the location of the tidal bridge can be influenced by the shock generated during the collision.

• The Bulletin of The Korean Astronomical Society
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• v.41 no.2
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• pp.64.1-64.1
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• 2016

We study the evolution of a late-type galaxy (LTG) in a rich cluster environment by using N-body/SPH simulations. To do that we perform a set of simulations of a LTG falling in a Coma-like cluster and also the LTG colliding with early-type galaxies (ETGs) multiple times in the cluster environment. We use a catalog of the Coma cluster in order to estimate the typical number of collisions and the closest approach distances that a LTG would experience in the cluster. We investigate the cold gas depletion and star formation quenching of our LTG model influenced by the hot cluster gas as well as the hot halo gas of the colliding ETGs.