• 한국보건간호학회지
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• 제36권3호
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• pp.309-322
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• 2022

Purpose: The purpose of this study was to identify factors associated with sugar-sweetened beverage consumption of Korean preschool children. Methods: Subjects for the study were recruited using the convenience sampling method. A total of 162 mothers with preschool children aged 3 to 5 years participated in the study using a self-reported questionnaire and provided data regarding the frequency and quantum of the children's sugar-sweetened beverage consumption days in a week and the factors associated with such consumption. Hierarchical multiple regression analysis was conducted to analyze the factors associated with the sugar-sweetened beverage consumption of preschool children. Results: Among the children-specific factors, age (β=.13, p=.015) was positively associated, while fruits/vegetable consumption (β=-.22, p<.001) was negatively associated with sugar-sweetened beverage consumption of the preschool children. Among the mother-specific factors, fruits/vegetable consumption of mothers was negatively associated (β=-.16, p=.006), while the sugar-sweetened beverage consumption of the mothers was positively associated with the sugar-sweetened beverage consumption of the preschool children (β=.27, p<.001). In addition, the maternal restrictive feeding style was negatively associated with sugar-sweetened beverage consumption of preschool children (β=-.23, p<.001). Conclusion: Based on these results, interventions targeted at children, parents, and the family environment should be developed to reduce the consumption of sugar-sweetened beverages in early childhood.

• Asian Pacific Journal of Cancer Prevention
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• 제14권4호
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• pp.2567-2570
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• 2013

Background: This study analyzed Surveillance, Epidemiology and End Results (SEER) data to assess if socio-economic factors (SEFs) impact on endometrial cancer survival. Materials and Methods: Endometrial cancer patients treated from 2004-2007 were included in this study. SEER cause specific survival (CSS) data were used as end points. The areas under the receiver operating characteristic (ROC) curve were computed for predictors. Time to event data were analyzed with Kaplan-Meier method. Univariate and multivariate analyses were used to identify independent risk factors. Results: This study included 64,710 patients. The mean follow up time (S.D.) was 28.2 (20.8) months. SEER staging (ROC area of 0.81) was the best pretreatment predictor of CSS. Histology, grade, race/ethnicity and county level family income were also significant pretreatment predictors. African American race and low income neighborhoods decreased the CSS by 20% and 3% respectively at 5 years. Conclusions: This study has found significant endometrial survival disparities due to SEFs. Future studies should focus on eliminating socio-economic barriers to good outcomes.

• IMMUNE NETWORK
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• 제12권4호
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• pp.129-138
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• 2012

Allergic disorders such as atopic dermatitis and asthma are common hyper-immune disorders in industrialized countries. Along with genetic association, environmental factors and gut microbiota have been suggested as major triggering factors for the development of atopic dermatitis. Numerous studies support the association of hygiene hypothesis in allergic immune disorders that a lack of early childhood exposure to diverse microorganism increases susceptibility to allergic diseases. Among the symbiotic microorganisms (e.g. gut flora or probiotics), probiotics confer health benefits through multiple action mechanisms including modification of immune response in gut associated lymphoid tissue (GALT). Although many human clinical trials and mouse studies demonstrated the beneficial effects of probiotics in diverse immune disorders, this effect is strain specific and needs to apply specific probiotics for specific allergic diseases. Herein, we briefly review the diverse functions and regulation mechanisms of probiotics in diverse disorders.

• Safety and Health at Work
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• 제9권1호
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• pp.63-70
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• 2018

Background: Psychosocial risk management [Psychosocial Risk Management Approach (PRIMA)] has, through the years, been applied in several organizations in various industries and countries globally. PRIMA principles have also been translated into international frameworks, such as PRIMA-EF (European framework) and the World Health Organization Healthy Workplace Framework. Over the past 10 years, an oil and gas company has put efforts into adopting and implementing international frameworks and standards for psychosocial risk management. More specifically, the company uses a PRIMA. Methods: This study explores available quantitative and qualitative risk data collected through the PRIMA method over the past 8 years in order to explore specific and common psychosocial risks in the petroleum industry. Results: The analyses showed a significant correlation between job resources and symptoms of work-related stress, there was a significant correlation between job demands and symptoms of work-related stress, and there were differences in psychosocial risk factors and symptoms of work-related stress onshore and offshore. The study also offers recommendations on how the results can further be utilized in building a robust system for managing psychosocial risks in the industry. Conclusion: The results from the analyses have provided meaningful and important information about the company-specific psychosocial risk factors and their impact on health and well-being.

• 한국응용곤충학회:학술대회논문집
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• 한국응용곤충학회 2005년도 춘계 학술발표회
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• pp.105-105
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• 2005

• 인지과학
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• 제28권3호
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• pp.133-147
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• 2017

인간의 지각은 외부환경을 객관적으로 반영하기 보다는 다양한 요인들에 의해 영향을 받은 결과이다. 이 요인들 중 행동-특정 지각은 환경에 대한 행위가능성에 의해 지각이 달라지는 현상이다. 기존 연구들은 행동-특정 지각이 과제를 수행하는 중에 발생하는지 아니면 수행 후 결과에 대한 지식 혹은 기억왜곡에 의한 것인지에 대해 상충된 결과를 보고하였다. 본 연구에서는 행동-특정 지각이 언제 발생하는지 확인하기 위해 다트를 사용하여 세 개의 실험을 실시하였다. 참가자들은 일정한 거리에서 다트를 수행하였으며 각 시행 후 지각된 표적의 크기를 응답지에 보고하였다. 그 결과 실험 1, 2에서 참가자들은 다트를 실패했을 때 보다 성공했을 때 표적을 더 크게 지각하였으며, 그 효과는 수행 후 표적을 볼 수 없을 때 더 강하게 발생하였다. 그러나 참가자들이 자신의 수행결과에 대해 알 수 있었기 때문에 응답에서 편파가 발생했을 가능성이 있었다. 이 가능성을 제거한 실험 3에서도 행동-특정 지각이 발생하였으며, 따라서 행동-특정 지각은 과제수행 후가 아닌 과제를 수행하는 동안 발생한다는 결론을 내릴 수 있었다.

• 한국안전학회지
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• 제12권1호
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• pp.113-121
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• 1997

Human reliability attempts to make precise quantitative analyses and predictions of the performance of human-machine(or product) systems. In order to yield more precise human error analysis, precise human error probabilities(HEPs) must be used in the analysis. However, because human behavior is influenced by factors that are called performance shaping factors(PSFs), the effects of PSFs must be considered to obtain precise HEPs, These are called basic HEPs or situation-specific HEPs. This paper presents a theoretical method for obtaining basic HEPs (i.e. , considering PSFs) in quantitative human error analysis. In this method, the weight which characterizes the degree of importance of several PSFs is obtained by the analytic hierarchy process. The quality scores of PSFs in the task situation are obtained by percentile concept. These scores are used in conjunction with the relative Importance weights of PSFs to compute the composite quality percentile score of PSFs in the task situation. Then, a new mapping method of the composite quality percentile score of PSFs into a situation-specific basic HEP is proposed with a numerical example.

• Molecules and Cells
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• 제21권3호
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• pp.376-380
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• 2006

Gene expression is regulated in large part at the level of transcription under the control of sequence-specific transcriptional regulatory proteins. Therefore, the ability to affect gene expression at will using sequencespecific artificial transcription factors would provide researchers with a powerful tool for biotechnology research and drug discovery. Previously, we isolated 56 novel sequence-specific DNA-binding domains from the human genome by in vivo selection. We hypothesized that these domains might be more useful for regulating gene expression in higher eukaryotic cells than those selected in vitro using phage display. However, an unpredictable factor, termed the "context effect", is associated with the construction of novel zinc finger transcription factors--- DNA-binding proteins that bind specifically to 9-base pair target sequences. In this study, we directly selected active artificial zinc finger proteins from a zinc finger protein library. Direct in vivo selection of constituents of a zinc finger protein library may be an efficient method for isolating multi-finger DNA binding proteins while avoiding the context effect.

• Clinical and Experimental Pediatrics
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• 제57권4호
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• pp.157-163
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• 2014

Respiratory distress syndrome (RDS) among preterm infants is typically due to a quantitative deficiency of pulmonary surfactant. Aside from the degree of prematurity, diverse environmental and genetic factors can affect the development of RDS. The variance of the risk of RDS in various races/ethnicities or monozygotic/dizygotic twins has suggested genetic influences on this disorder. So far, several specific mutations in genes encoding surfactant-associated molecules have confirmed this. Specific genetic variants contributing to the regulation of pulmonary development, its structure and function, or the inflammatory response could be candidate risk factors for the development of RDS. This review summarizes the background that suggests the genetic predisposition of RDS, the identified mutations, and candidate genetic polymorphisms of pulmonary surfactant proteins associated with RDS.

• 한국식생활문화학회지
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• 제11권3호
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• pp.299-304
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• 1996

The objective of this study was to investigate important factors affecting food choice, specific dietary changes over past few years and to find out consumer opinions concerning the use of yogurt and oligosaccharides. Results of this study showed that three most important factors in food selection were taste (52.5%), nutrition (23.4%) and safety (15.8%). Three most important nutritive factors were protein (26.3%), calorie (19.2%) and vitamin (13.8%). Specific dietary changes of the respondent over past few years didn't affect meat intake, but increased vegetable and fruit intakes. Majority of the respondent (52.3%) ate yogurt more than 3 times per week and 35.6% of them ate $3{\sim}4$ times per month. Reasons for intake of oligosaccharides were as follows; low calorie (40.8%), sweetener (28.3%)and bifidogenic factor (25.0%). The respondent regarded that yogurt had more preventive effect of disease than that of oligosaccharide.