• 제목/요약/키워드: Specific Factors

검색결과 4,947건 처리시간 0.039초

Optimization of Predictors of Ewing Sarcoma Cause-specific Survival: A Population Study

  • Cheung, Min Rex
    • Asian Pacific Journal of Cancer Prevention
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    • 제15권10호
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    • pp.4143-4145
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    • 2014
  • Background: This study used receiver operating characteristic curve to analyze Surveillance, Epidemiology and End Results (SEER) Ewing sarcoma (ES) outcome data. The aim of this study was to identify and optimize ES-specific survival prediction models and sources of survival disparities. Materials and Methods: This study analyzed socio-economic, staging and treatment factors available in the SEER database for ES. 1844 patients diagnosed between 1973-2009 were used for this study. For the risk modeling, each factor was fitted by a Generalized Linear Model to predict the outcome (bone and joint specific death, yes/no). The area under the receiver operating characteristic curve (ROC) was computed. Similar strata were combined to construct the most parsimonious models. Results: The mean follow up time (S.D.) was 74.48 (89.66) months. 36% of the patients were female. The mean (S.D.) age was 18.7 (12) years. The SEER staging has the highest ROC (S.D.) area of 0.616 (0.032) among the factors tested. We simplified the 4-layered risk levels (local, regional, distant, un-staged) to a simpler non-metastatic (I and II) versus metastatic (III) versus un-staged model. The ROC area (S.D.) of the 3-tiered model was 0.612 (0.008). Several other biologic factors were also predictive of ES-specific survival, but not the socio-economic factors tested here. Conclusions: ROC analysis measured and optimized the performance of ES survival prediction models. Optimized models will provide a more efficient way to stratify patients for clinical trials.

A Study on the Method of Safety Condition Evaluation using Analytic Hierarchy Process (AHP를 이용한 기업별 안전평가 기법에 관한 연구)

  • Paik, Shinwon;Lee, Misun
    • Journal of The Korean Society of Agricultural Engineers
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    • 제55권3호
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    • pp.85-89
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    • 2013
  • In the current domestic, many industrial accidents have happened. And these are analyzed according to several factors. But it is difficult that they evaluate their business safety. Thus, we conducted a study on business specific safety assessment techniques in order that business know their safety level and perform appropriative safety activities. Study methods are survey and AHP (Analytic Hierarchy Process). Each specific weighting factors to calculate the survey was conducted for safety and consulting experts (20 persons). Weight factor was used to AHP decision support as one of the ways through a number of alternatives to the ratings for the Minesota Multiphasic. Factors are each type of industry, specific industrial scale, disaster type and strength, worker age and tenure period, and region. First, survey was conducted with 20 professionals to estimate the weighting factors. Weights between factors using the AHP analysis tool based on the mean values were calculated. Second, last 3 years between the industrial accidents statistics were used to calculate the weights for each of the rating factors in the Occupational Safety and Health Agency. Grade weights between each factor which was based on the rating of each factor was calculated as the average of three years. Finally, the weights between each factor and the grade weights for each factor using the safety level of the enterprise were calculated so that you can evaluate the weighting.

Socioeconomic Predictors of Diabetes Mortality in Japan: An Ecological Study Using Municipality-specific Data

  • Okui, Tasuku
    • Journal of Preventive Medicine and Public Health
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    • 제54권5호
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    • pp.352-359
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    • 2021
  • Objectives: The aim of this study was to examine the geographic distribution of diabetes mortality in Japan and identify socioeconomic factors affecting differences in municipality-specific diabetes mortality. Methods: Diabetes mortality data by year and municipality from 2013 to 2017 were extracted from Japanese Vital Statistics, and the socioeconomic characteristics of municipalities were obtained from government statistics. We calculated the standardized mortality ratio (SMR) of diabetes for each municipality using the empirical Bayes method and represented geographic differences in SMRs in a map of Japan. Multiple linear regression was conducted to identify the socioeconomic factors affecting differences in SMR. Statistically significant socioeconomic factors were further assessed by calculating the relative risk of mortality of quintiles of municipalities classified according to the degree of each socioeconomic factor using Poisson regression analysis. Results: The geographic distribution of diabetes mortality differed by gender. Of the municipality-specific socioeconomic factors, high rates of single-person households and unemployment and a high number of hospital beds were associated with a high SMR for men. High rates of fatherless households and blue-collar workers were associated with a high SMR for women, while high taxable income per-capita income and total population were associated with low SMR for women. Quintile analysis revealed a complex relationship between taxable income and mortality for women. The mortality risk of quintiles with the highest and lowest taxable per-capita income was significantly lower than that of the middle-income quintile. Conclusions: Socioeconomic factors of municipalities in Japan were found to affect geographic differences in diabetes mortality.

A Study on Factors Affecting Public Health Center Workforce for Health Behavior based on Pender's Health Promotion Model (서울지역 일부 보건소 공무원의 지각된 건강상태와 건강행동과의 관련성 -Pender의 건강증진모델을 이용하여-)

  • Lee, Eun-Jeoung;Lee, Myung-Sun
    • The Journal of Korean Society for School & Community Health Education
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    • 제15권1호
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    • pp.121-140
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    • 2014
  • Objectives: Recently, the rate of death by chronic disease, is increasing steadily. To prevent this, the public health center will have taken a leading role in the local community medical business through an establish to the national health promotion act and an amendment to the law of public health center in Korea. Results: Accordingly this research, using the Pender's health promotion model which is related with subject health behavior who government employees serve at the public health center have taken important position in the local community health promotion, have comprehended the actual condition of health behavior. For increasing the health behavior practice of subject to comprehend the factor which have effect on health behavior practice, which can be a correct role model in the local community health promotion. A survey was performed on 406 government employees who serve at five public health centers in Seoul. The period of survey was from 25th October, 2010 to 15th November, 2010. The results of this study were summarized as below. 1. Work-related stress, perceptible beneficial obstacle, and self-efficacy were composed by 5 points measure. The results show those work-related stress were $3.06{\pm}0.469$, 74perceptible beneficial obstacle were $3.74{\pm}0.471$, and self-efficacy were $3.49{\pm}0.469$. 2. As for the health behavior by general characteristic, the results have specific differences on age, education level, state of marriage, rank of the position, field of the occupation and employment forms in statics analysis. 3. As for the past health behavior by health behavior characteristic, work-related stress have specific differences on the past frequency of drinking (p<.05) in statics analysis, perceptible beneficial obstacle have specific differences on the past frequency of having breakfast(p<.05), having snacks(p<.05) and doing exercise(p<.05) in statics analysis. Self-efficacy have specific difference on the past frequency drinking(p<.01) in statics analysis. 4. According to the correlation between the factors related with health behavior and health behavior, the health behavior have specific differences on perceptible health condition(p<.01), the past health behavior and perceptible beneficial obstacle(p<.05). Work-related stress and self-efficacy don't have specific relation in health behavior practice. 5. The factors, which effect on health behavior practice have specific differences on the past health behavior, employment forms and field of the occupations. The ability of explanation occupied 54.8% what explained of the health behavior practice by general characteristic, perceptible health condition, employment forms and perceptible beneficial obstacle. Conclusions: According to the correlation between the factors related with health behavior, the health behavior have specific differences on perceptible health condition(p<.01), the past health behavior and perceptible beneficial obstacle(p<.05). The factors, which effect on health behavior practice have specific differences on the past health behavior, employment forms and field of the occupations.

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An empirical study on factors for effective BPMS implementaion focusing on resistance against monitoring function (BPMS의 전사적 구축 성공 요인에 대한 실증 연구 - 모니터링 기능에 대한 저항을 중심으로)

  • Chae, Myeong-Sin;Park, Jin-Seok;Lee, Byeong-Tae
    • Proceedings of the Korean Operations and Management Science Society Conference
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    • 한국경영과학회 2006년도 추계학술대회
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    • pp.211-231
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    • 2006
  • This study integrated the factors for enterprise-wide IS implementation and BPMS-specific factors to examine factors for effective BPMS implementation. We interviewed IT-consultants and CIOs who conducted BPMS projects. As a result, monitoring function has been agreed as a main BPMS-specific factor. We reviewed literature on BPMS implementation and Computer-based monitoring and integrated the factors from the literature with TAM. We used structural equation modeling to test hypotheses and found some organizational factors such as reward management, boss' fairness were significant.

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Promoting and Inhibiting Factors on Information Sharing between Buyers and Sellers (유통경로 내 구매자와 판매자 간 정보공유의 촉진요인과 억제요인)

  • Kim, Sang-Deok
    • Knowledge Management Research
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    • 제10권2호
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    • pp.1-14
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    • 2009
  • This study has investigated the effects of promoting and inhibiting factors on information sharing between buyers and sellers in Korean distribution industry. Based on intensive literature reviews, eight promoting factors(satisfaction, relational norms, trust, commitment, fairness, formalization, participation, transaction specific investment) and five inhibiting factors(opportunism, environmental uncertainty, conflict, concentration, monitoring) were included in the research model. For the purpose of empirical testing, 320 respondents of retailers in Korea were surveyed and the analysis utilizing structural equation model indicated that satisfaction, relational norms, trust, commitment, fairness, formalization, and participation had positive effects on information sharing. And concentration and monitoring had negative effects on it. However transaction specific investment, opportunism, conflict, and environmental uncertainty had no significant effects.

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A comparison of new product success factors across advanced countries: A multi-level approach (선진국 제조기업의 신제품 성공요인에 관한 비교 연구: 다수준 접근 방식)

  • Lee, Youngwoo;Cho, Youngsam
    • Knowledge Management Research
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    • 제21권2호
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    • pp.59-75
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    • 2020
  • In this paper, we investigate the influence of factors on the firm, industry, and country levels on the new product development performance (NPD) of manufacturing firms in advanced economies. The resource-based view, industrial organization theory and institutional theory have established that firm-, industry- and country-level factors are all relevant for the NPD of firms. However, little is known about the relative importance of factors at the three different levels across countries, as prior studies on firms' NPD have focused on specific countries and levels of analysis. Our analysis of survey data from 1,437 manufacturing firms in nine advanced OECD countries shows that while firm-level factors are generally better predictors of firms' innovativeness than either industry- or country-level factors, the results strongly differ across countries, indicating that the relative importance of antecedents of innovativeness is country-specific rather than universal.

Assessing the Impact of Socio-economic Variables on Breast Cancer Treatment Outcome Disparity

  • Cheung, Min Rex
    • Asian Pacific Journal of Cancer Prevention
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    • 제14권12호
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    • pp.7133-7136
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    • 2013
  • Background: We studied Surveillance, Epidemiology and End Results (SEER) breast cancer data of Georgia USA to analyze the impact of socio-economic factors on the disparity of breast cancer treatment outcome. Materials and Methods: This study explored socio-economic, staging and treatment factors that were available in the SEER database for breast cancer from Georgia registry diagnosed in 2004-2009. An area under the receiver operating characteristic curve (ROC) was computed for each predictor to measure its discriminatory power. The best biological predictors were selected to be analyzed with socio-economic factors. Survival analysis, Kolmogorov-Smirnov 2-sample tests and Cox proportional hazard modeling were used for univariate and multivariate analyses of time to breast cancer specific survival data. Results: There were 34,671 patients included in this study, 99.3% being females with breast cancer. This study identified race and education attainment of county of residence as predictors of poor outcome. On multivariate analysis, these socio-economic factors remained independently prognostic. Overall, race and education status of the place of residence predicted up to 10% decrease in cause specific survival at 5 years. Conclusions: Socio-economic factors are important determinants of breast cancer outcome and ensuring access to breast cancer treatment may eliminate disparities.

Nanofibrous Meshes Promoting Celular Proliferation

  • Yu, Hyeok-Sang;Choe, Ji-Suk;Kim, Hye-Seong
    • Proceedings of the Materials Research Society of Korea Conference
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    • 한국재료학회 2011년도 추계학술발표대회
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    • pp.2.1-2.1
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    • 2011
  • Biomedical applications of electrospun nanofibrous meshes have been receive tremendous attentions because of their unique structures and versatilities as novel biomaterials. Incorporation of growth factors in fibrous meshes can be performed by surface-modification and encapsulation. Those growth factors stimulate differentiation and proliferation of specific types of cells and thus lead tissue regenerations of specific cell types. Topographical cues of electrospun nanofibrous meshes also increase differentiation of specific cell types according to alignments of fibrous structures. Wound healing treatments of diabetic ulcers were performed using nanofibrous meshes encapsulating multiple growth factors. Aligned nanofibrous meshes and those with random configuration were compared for differentiating mesenchymal stem cells into neuronal cells. Thus, nanofibrous meshes can be applied to novel drug delivery carriers and matrix for promoting cellular proliferation.

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The Choice between Shared vs. Full Ownership : The Case of Korean Multinational Corporations (한국 다국적기업의 해외진출에 대한 지분선택 : 현지합작 대비 단독투자)

  • Park, Young-Kyu;Park, Young-Ryeol
    • THE INTERNATIONAL COMMERCE & LAW REVIEW
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    • 제24권
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    • pp.107-125
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    • 2004
  • This study is based on the survey data of 74 Korean multinational corporations, which undertook foreign direct investments from 1980 to 1996. The study examined the firm-specific as well as the host country-specific factors affecting the decision between shared and full ownership. According to the results of this study, as for the firm-specific factors, Korean firms entering foreign markets in order to penetrate local markets prefer shared ownership while those pursuing core business diversification prefer full ownership. As for the host country factors, the more advanced the host country(such as OECD countries) is, the more preference is given to full ownership.

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