• Journal of Ginseng Research
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• 제40권3호
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• pp.245-250
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• 2016

Background: Ginsenosides are the major effective ingredients responsible for the pharmacological effects of ginseng. Malonyl ginsenosides are natural ginsenosides that contain a malonyl group attached to a glucose unit of the corresponding neutral ginsenosides. Methods: Medium-pressure liquid chromatography and semipreparative high-performance liquid chromatography were used to isolate purified compounds and their structures determined by extensive one-dimensional- and two-dimensional nuclear magnetic resonance (NMR) experiments. Results: A new saponin, namely malonyl-ginsenoside Re, was isolated from the fresh flower buds of Panax ginseng, along with malonyl-ginsenosides Rb1, Rb2, Rc, Rd. Some assignments for previously published $^1H$- and $^{13}C$-NMR spectra were found to be inaccurate. Conclusion: This study reports the complete NMR assignment of malonyl-ginsenoside Re, $Rb_1$, $Rb_2$, Rc, and Rd for the first time.

• 한국한의학연구원논문집
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• 제4권1호통권4호
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• pp.63-98
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• 1998

Background and Purpose : To investigate the wild plants to be used for survival on tactical activity of Special Forces soldiers at deep enemy's territory Material and Methods : To investigate the wild plants, I selected various native plants in the forests and fields that can be used for medical cure and eatables. And I selected some poisonous plants and some plants containing water or salts, after due consideration of tactical activity and use in the battle-fields. Results and Conclusion : There are many wild plants to be used for multiple purpose in our country. We can get from these plants emergency medicines, foods, even water and salts. I chose 6 species of digestives, 11 species of analgesics, 9 species of antiphlogistics, 7 species of hemostatics, 5 species of antidiarheal, 5 species of diuretics, 2 species of laxatives, 7 species of antipyretics, 1 species of vermicide and 45 species of eatable plants and 12 species of poisonous plants. and I summarized general name, scientific name, component, picking season, used portion, taking method of these plants. Building up accurate knowledge on the wild plants could contributed to raise survival rate of Special Forces soldiers in the battle-fields.

• Journal of Ginseng Research
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• 제42권1호
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• pp.27-34
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• 2018

Background: The use of different methods for the processing of ginseng can result in alterations in its medicinal properties and efficacy. White ginseng (WG), frozen ginseng (FG), and red ginseng (RG) are produced using different methods. WG, FG, and RG possess different pharmacological properties. Methods: WG, FG, and RG extracts and pure ginsenosides were administered to rats to study the pharmacokinetics and tissue distribution characteristics of the following ginsenosides-DRg1, Re, Rb1, and Rd. The concentrations of the ginsenosides in the plasma and tissues were determined using UPLC-MS/MS. Results: The rate and extent of absorption of Rg1, Re, Rb1, and Rd appeared to be affected by the different methods used in processing the ginseng samples. The areas under the plasma drug concentration-time curves (AUCs) of Rg1, Re, Rb1, and Rd were significantly higher than those of the pure ginsenosides. In addition, the AUCs of Rg1, Re, Rb1, and Rd were different for WG, FG, and RG. The amounts of Rg1, Re, Rd, and Rb1 were significantly (p < 0.05) higher in the tissues than those of the pure ginsenosides. The amounts of Re, Rb1, and Rd from the RG extract were significantly higher than those from the WG and FG extracts in the heart, lungs, and kidneys of the rats. Conclusion: Our results show that the use of different methods to process ginseng might affect the pharmacokinetics and oral bioavailability of ginseng as well as the tissue concentrations of Rg1, Re, Rd, and Rb1.

• 한국환경복원기술학회지
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• 제20권3호
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• pp.33-44
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• 2017

This study investigated in the vascular plants of special protection zones (the native land of Berchemia berchemiaefolia in Sadam-ri and Gallon valley) of Songnisan National Park and identified the whole vascular plants. The numbers of vascular plants were summarized as 273 taxa including 82 families, 182 genera, 236 species, 3 subspecies, 28 varieties and 6 forms. Woody plants were identified as 124 taxa (45.4%) and herbaceous plants as 149 taxa (54.6%). A total of 107 taxa were identified in the area of Sadam-ri, and 246 taxa were found in the Gallon valley. A total of 8 taxa of rare plants were identified, each of which was divided into 1 taxa of endangered (EN; Daphne pseudomezereum var. koreana), 3 taxa of vulnerable (VU; Paeonia japonica, Berchemia berchemiaefolia and Iris minutiaurea), 3 taxa of least concern (LC; Aristolochia contorta, Syringa patula var. kamibayshii and Goodyera schlechtendaliana) and 1 taxa of data deficient (DD; Alangium platanifolium). The Korean endemic plants were 9 taxa (Clematis trichotoma, Thalictrum actaefolium var. brevistylum, Aster koraiensis, Cirsium setidens, etc.). In the specific plants by floristic region were 34 taxa, a degree I were 17 taxa (Chloranthus japonicus, Celastrus stephanotifolius, etc.), 9 taxa of a degree II (Euonymus pauciflorus, Acer triflorum, etc.), 4 taxa of a degree III (Aconitum longecassidatum, Angelica gigas, etc.), 2 taxa of a degree IV (Ulmus macrocarpa and Daphne pseudomezereum var. koreana), 2 taxa of a degree V (Berchemia berchemiaefolia and Alangium platanifolium). The naturalized plants were 5 taxa including Fallopia dumetorum, Trifolium repens, Ailanthus altissima, Oenothera biennis, Erigeron annuus. Naturalization rate (NR) was 1.8% of all 273 taxa of vascular plants and the invasive alien plants were not found. The purpose of this study is to identify the flora that grows in the special protection zones of Songnisan National Park and provide the basic data for the management of the special protection zone in the future.

• Journal of Ginseng Research
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• 제41권2호
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• pp.209-214
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• 2017

Background: Both ginsenoside Re and B-complex vitamins are widely used as nutritional supplements. They are often taken together so as to fully utilize their antifatigue and refreshing effects, respectively. Whether actually a drug-nutrient interaction exists between ginsenoside Re and B-complex vitamins is still unknown. The objective of this study was to simultaneously investigate the effect of B-complex vitamins on the antifatigue activity and bioavailability of ginsenoside Re after their oral administration. The study results will provide valuable theoretical guidance for the combined utilization of ginseng and B-complex vitamins. Methods: Ginsenoside Re with or without B-complex vitamins was orally administered to mice to evaluate its antifatigue effects and to rats to evaluate its bioavailability. The antifatigue activity was evaluated by the weight-loaded swimming test and biochemical parameters, including hepatic glycogen, plasma urea nitrogen, and blood lactic acid. The concentration of ginsenoside Re in plasma was determined by liquid chromatography-tandem mass spectrometry. Results: No antifatigue effect of ginsenoside Re was noted when ginsenoside Re in combination with B-complex vitamins was orally administered to mice. B-complex vitamins caused to a reduction in the bioavailability of ginsenoside Re with the area under the concentration-time curve from zero to infinity markedly decreasing from $11,830.85{\pm}2,366.47h{\cdot}ng/mL$ to $890.55{\pm}372.94h{\cdot}ng/mL$. Conclusion: The results suggested that there were pharmacokinetic and pharmacodynamic drug-nutrient interactions between ginsenoside Re and B-complex vitamins. B-complex vitamins can significantly weaken the antifatigue effect and decrease the bioavailability of ginsenoside Re when simultaneously administered orally.

• 한국약용작물학회지
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• 제19권6호
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• pp.407-413
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• 2011

This study was analyzed and investigated to evaluate ecological distribution of medicinal plants in Miho Stream of Korea. Totality 463 taxa of vascular plants were appeared in lower part of Miho Stream. Medicinal plants were distributed 253 taxa, which were 54.6% of the total vascular plants appeared. Medicinal plants of official drug compendium(Korean pharmacopoeia) were 85 taxa. Medicinal plants were distributed most of the forest area, and followed field surrounding, stream surrounding and paddy surrounding respectively. The distribution of life form hemicryptophyte was the most frequent. Plant community of appearing area of medicinal plants was classified into Salix koreensis, Phragmites japonica, Echinochloa crusgalli, Artemisia selengensis, Miscanthus sacchariflorus, Setaria faberii, Panicum dichotomiflorum, Bidens frondosa, Humulus japonicus, Monochoria vaginalis var. plantaginea, Eleocharis kuroguwai, Erigeron acris, Pinus densiflora, Pinus rigida, Quercus acutissima, Quercus serrata, Robinia pseudoacacia and Castanea crenata community. Medicinal plants in plant communities that occur frequently were Humulus japonicus, Corylus heterophylla and Liriope spicata.

• 한국자원식물학회지
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• 제21권4호
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• pp.310-323
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• 2008

본 조사연구는 황장산(1,077.3m)의 관속식물 분포를 파악하기 위하여 수행하였다. 2006년 4월부터 2007년 8월까지 9회에 걸쳐 채집된 관속식물은 97과 257속 357종 5아종 42변종 9품종, 총 413분류군이었다. 이는 한반도에 분포하는 관속식물 4,071종류의 10.1%에 해당하였다. 특기할만한 식물로는 한국특산식물이 6분류군이었고 산림청 지정 희귀 및 멸종위기종은 8 분류군이었으며 식물구계학적 특정식물은 55분류군이었고 귀화식물은 7과 15분류군으로 우리나라 귀화식물 290종류(김과이, 2006)의 5.2%이고, 소산식물의 3.6%가 분포한다.

• 한국육종학회지
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• 제42권5호
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• pp.431-438
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• 2010

Anthers of sweet pepper $F_1$ cultivar 'Special' were cultured on Dumas De Vaulx (C medium), supplemented with $0.1mgL^{-1}$ 2, 4-D and $0.1mg{\cdot}L^{-1}$ kinetin with 3% sucrose, and 0.32% phytagel. The calluses obtained were further sub-cultured on Murashige and Skoog (MS) medium without growth regulators for regeneration. Regenerated plantlets were grown in plastic pots under plastic house and characterized their cytological and morphological characters in spring, 2008. Twenty percent plantlets were identified as haploid plants after chromosome and ploidy analysis. Haploid plants contained 12 chromosomes, high stomatal density with small stomatal length as compared to diploid plants. Stomatal length in haploids was 23.3% smaller than diploids. Haploid plants were characterized as small leaf and petiole size, poor vigor, thin stem and short plant height, short internodes and small flower buds, fruit size and fruit weight as compared to diploid plants and most of the haploid fruits were seedless. SP55, SP62, SP68, SP72 and SP77 are found high yielding double haploids with high total soluble content (8.6, 8.7, 9.2, 9.1 and $9.8^{\circ}Brix$, respectively) and desirable fruit shape, and recommended them to exploit as inbred lines for heterosis breeding.

• 한국응용곤충학회지
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• 제34권1호
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• pp.1-8
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• 1995

The relationships between aphids, plants, other organisms and some physical components of the environment are reviewed. Aspects considered include year cycles, polymorphism fecundity, relationship of different groups of aphids with particular groups of plants, honeydew, alarm pheromones, aposematic colouring, camouflage, colour variation within species, morphological variation within species, multivariate analysis and problems of its interpretation, parasitism, stridulating mechanisms, predators, coevolution of plants and aphids, plant galls, trapping aphids and the interpretation of trap catches, an curation of aphid collections. References are given to sources of information about aphids, with special reference to the Korean fauna.

• 한국환경생태학회지
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• 제29권6호
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• pp.819-841
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• 2015

본 연구는 소백산맥 중 덕유산과 백운산의 사이에 위치한 할미봉(1,026m)과 구시봉(1,014m)을 대상으로 주요 관속식물상을 파악하여 주요식물에 대한 효율적인 관리와 보전 및 그 일대 식물자원의 기초자료를 제공하기 위해 수행하였다. 현지조사는 2013년 3월부터 2014년 3월까지 계절별 조사를 실시하였으며, 조사경로는 계곡부, 능선부, 사면부 등을 포함하여 조사를 실시하였다. 조사 결과 할미봉과 구시봉 일대에서 출현한 관속식물은 총 95과 287속 454종 4아종 59변종 11품종 528분류군이 조사되었다. 희귀식물은 EN등급(위기종) 1분류군(흰참꽃나무), VU등급(취약종) 2분류군(쇠채, 솔나리), LC등급(약관심종) 12분류군(구상나무, 매미꽃, 태백제비꽃 등) 총 10과 14속 13종 2변종 15분류군이 조사되었다. 특산식물은 처녀치마 등 15분류군이 나타났다. 식물구계학적 특정식물 V등급은 승마 등 2분류군, IV등급은 개대황 등 6분류군, III등급은 거제수나무 등 12분류군이 각각 출현하여 I등급부터 V등급까지 총 32과 52속 58종 1아종 2변종 61분류군이 출현하였다. 귀화식물은 소리쟁이, 족제비싸리, 선개불알풀 등 23종이 출현하였다.