• Journal of Digital Convergence
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• v.11 no.10
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• pp.577-584
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• 2013

IGRT(Image Guided Radiation Therapy) in radiation therapy is a very useful technique in order to increase setup of patient and position reproducibility. Tomotherapy can increase accuracy of setup to take IGRT by MVCT, but it be for verified accuracy of Image guided, and MVCT occurs the exposure of patient. Through this study, IGRT accuracy of Tomotherapy is very accurate within 1.0mm. When MVCT using Tomotherapy phantom for QA, QC be taken, exposure dose is Fine(2mm Slice thickness) 3cGy, Normal(4mm Slice thickness) 1.5cGy, Corse(6mmSlice thickness) 1.0cGy. Measurement value of spatial resolution using AAPM CT performance phantom did't cause a big difference. As a result, ability of IGRT in Tomotherapy is very accurate. While obtaining image for IGRT, we should minimize expose range because patient's be exposed to radiation. We should make an effort to do accurate radiation therapy to minimize exposure of patient by selecting the appropriate thickness of MVCT depending on patient's body and treat area.

• 대한공업교육학회지
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• v.44 no.2
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• pp.1-27
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• 2019

In recent years, space planning ability using 3D sketch software is required in the working field of interior design. However, vocational high school do not respond appropriately to changes in the industry, because the class of vocational high school consists of hands-on practical classes and 2D CAD based classes. There is a shortage of 3D sketch software-based instruction programs that can improve students' spatial planning skills. Therefore, this study is to develop instruction program using 3D sketch software for 'Planning for Residential Space' unit of NCS-based on interior design subject and to find out the effect on students' academic achievement by applying to vocational high school class. The 3d sketch software based instructional program developed in this study was developed through four stages of preparation, development, implementation and evaluation according to the PDIE model process. The experimental design model used nonequivalent group posttest-only design in this study. Experiments were conducted on vocational high school students in construction and 9 hours of interior design subjects were applied. After the experiments, students were tested for academic achievement in the cognitive, affective, and psychomotor areas. As a result, the instruction program using the 3d sketch program developed in this study was found to be more effective in improving students' academic achievement than existing manual instruction program in both cognitive, affective, and psychomotor areas.

• Journal of Energy Engineering
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• v.8 no.4
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• pp.567-575
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• 1999

This study found potential ability to generate electric power using difference in water temperature between sea surface water and deep water in the East Sea which includes the East Sea Proper Water with the temperature less than 1$^{\circ}C$ throughout a year without seasonal variation. To quantify the difference in water temperature between sea surface water and deep water in the East Sea. We computed the annual mean ($^{\circ}C$), the annual amplitude ($^{\circ}C$), the annual phase (degree) and the duration time which showed more than 15$^{\circ}C$ temperature difference from the water temperature data using Harmonic analysis during 1961~1997. The best place for generating electric power in the East Sea seems to be the eastward ocean areas (36$^{\circ}$ 05'N, 129$^{\circ}$ 48'E~36$^{\circ}$ 05'N, 130$^{\circ}$ 00E'E) from Pohang city. The annual mean of the difference in water temperature between sea surface water and 500 m depth was 24$^{\circ}$C at the place to generate electric power in August according to the data of 1961~1997. the maximum duration periods with more than 15$^{\circ}C$ temperature difference were 215 days (5/5-12/10) a year in the place mentioned electricity with a stable plan. In the East Sea coastal areas of the Korean peninsula, the average minimum depth to reach the East Sea Proper Water from surface water is 300 m and fluctuates between 250 m and 350 m throughout a year. Further studies could be needed for the utilization of cold water, such as the East Sea Proper Water for energy conversion.

• Nutrition Research and Practice
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• v.12 no.3
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• pp.191-198
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• 2018

BACKGROUD/OBJECTIVES: Neuroinflammation plays critical role in neurodegenerative disorders, such as Alzheimer's disease (AD). We investigated the effect of three licorice varieties, Glycyrhiza uralensis, G. glabra, and Shinwongam (SW) on a mouse model of inflammation-induced memory and cognitive deficit. MATERIALS/METHODS: C57BL/6 mice were injected with lipopolysaccharide (LPS; 2.5 mg/kg, intraperitoneally) and orally administrated G. uralensis, G. glabra, and SW extract (150 mg/kg/day). SW, a new species of licorice in Korea, was combined with G. uralensis and G. glabra. Behavioral tests, including the T-maze, novel object recognition and Morris water maze, were carried out to assess learning and memory. In addition, the expressions of inflammation-related proteins in brain tissue were measured by western blotting. RESULTS: There was a significant decrease in spatial and objective recognition memory in LPS-induced cognitive impairment group, as measured by the T-maze and novel object recognition test; however, the administration of licorice ameliorated these deficits. In addition, licorice-treated groups exhibited improved learning and memory ability in the Morris water maze. Furthermore, LPS-injected mice had up-regulated pro-inflammatory proteins, such as inducible nitric oxide synthase (iNOS), cyclooxygenase-2, interleukin-6, via activation of toll like receptor 4 (TLR4) and nuclear factor-kappa B ($NF{\kappa}B$) pathways in the brain. However, these were attenuated by following administration of the three licorice varieties. Interestingly, the SW-administered group showed greater inhibition of iNOS and TLR4 when compared with the other licorice varieties. Furthermore, there was a significant increase in the expression of brain-derived neurotrophic factor (BDNF) in the brain of LPS-induced cognitively impaired mice that were administered licorice, with the greatest effect following SW treatment. CONCLUSIONS: The three licorice varieties ameliorated the inflammation-induced cognitive dysfunction by down-regulating inflammatory proteins and up-regulating BDNF. These results suggest that licorice, in particular SW, could be potential therapeutic agents against cognitive impairment.

• Journal of Korea Water Resources Association
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• v.43 no.8
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• pp.721-731
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• 2010

The rainfall-runoff relationship is very difficult to predict because it is complicate factor affected by many temporal and spatial parameters of the basin. In recent, models which is based on artificial intelligent such as neural network, genetic algorithm fuzzy etc., are frequently used to predict discharge while stochastic or deterministic or empirical models are used in the past. However, the discharge data which are generally used for prediction as training and validation set are often estimated from rating curve which has potential error in its estimation that makes a problem in reliability. Therefore, in this study, water stage is predicted from antecedent rainfall and water stage data for short term using three models of neural network which trained by error back propagation algorithm and optimized by genetic algorithm and training error back propagation after it is optimized by genetic algorithm respectively. As the result, the model optimized by Genetic Algorithm gives the best forecasting ability which is not much decreased as the forecasting time increase. Moreover, the models using stage data only as the input data give better results than the models using precipitation data with stage data.

• Korean Journal of Comparative Education
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• v.28 no.3
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• pp.333-354
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• 2018

The study aimed to compare and analyze Nuri curriculum and contents for mathematics in Korea and the Common Core State Standards(CCSS) and New Jersey Preschool Standards for mathematics in the United States. With the results as basis, this study intended to provide suggestions and directions for improving Nuri curriculum of mathematics for young children. For the goal of this study, educational goals, categories of contents, and specific contents were reviewed. First, results of this study indicated that Nuri curriculum for mathematics provides comprehensive educational goals that promote problem-solving ability in everyday contexts with composing mathematical knowledge. On the contrary, CCSS and Preschool Standards provide specific educational goals that focus on children's mathematical skills and concepts. Second, the contents of both countries' curriculum concentrate on 'counting and cardinality', 'measurement', and 'spatial and geometric sense.' There are 5 categories of CCSS, 4 categories of Preschool Standards based on CCSS and one category of Nuri curriculum for mathematics. Third, there are the differences between the two countries' curriculum in continuity from kindergarten to first grade and description method for curriculum.

• Geophysics and Geophysical Exploration
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• v.1 no.1
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• pp.31-42
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• 1998

Recently crosshole seismic tomography has come to be widely used especially for the civil engineering, because it can provide more detail information than any other surface method, although the resolution of tomogram will be inevitably deteriorated to some extent due to the limited wavefield aperture on the nonuniqueness of traveltime inversion. In addition, our field sites often consist of a high-velocity bed rock overlain by low-velocity rock, sometimes with a contrast of more than 45 percent, and furthermore the bed rock is folded. The first arriving waves can be then the refracted ones that travel along the bed rock surface for some source/receiver distances. Thus, the desirable first arrivals can be easily misread that cause severe distortion of the resulting tomogram, if it is concerned with (straight ray) traveltime inversion procedure. In this case, comparision with synthetic data (forward modeling) is a valuable tool in the interpretation process. Besides, abundant information is contained in the crosshole data. For instance, examination of tube waves can be devoted to detecting discontinuities within the borehole such as breakouts, faults, fractures or shear zones as well as the end of the borehole. Specific frequency characteristics of marine silty mud will help discriminate from other soft rocks. The aim of this paper is to present several strategies to analyze and interpret the crosshole data in order to improve the ability at first to determine the spatial dimensions of interwell anomalies and furthermore to understand the underground structures. To this end, our field data are demonstrated. Possibility of misreading the first arrivals was illustrated. Tube waves were investigated in conjunction with the televiewer images. Use of shot- and receiver gathers was examined to benefit the detectabilities of discontinuities within the borehole.

• Korean Journal of Remote Sensing
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• v.37 no.6_2
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• pp.1803-1818
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• 2021

As the frequency of drought increases due to climate change, it is very important to have a monitoring system that can accurately determine the situation of widespread drought. However, while ground-based meteorological data has limitations in identifying all the complex droughts in Korea, satellite remote sensing data can be effectively used to identify the spatial characteristics of drought in a wide range of regions and to detect drought. This study attempted to analyze the possibility of using remote sensing data for drought identification in South Korea. In order to monitor various aspects of drought, remote sensing and ground observation data of precipitation and potential evapotranspiration, which are major variables affecting drought, were collected. The evaluation of the applicability of remote sensing data was conducted focusing on the comparison with the observation data. First, to evaluate the applicability and accuracy of remote sensing data, the correlations with observation data were analyzed, and drought indices of various aspects were calculated using precipitation and potential evapotranspiration for meteorological drought monitoring. Then, to evaluate the drought monitoring ability of remote sensing data, the drought reproducibility of the past was confirmed using the drought index. Finally, a high-resolution drought map using remote sensing data was prepared to evaluate the possibility of using remote sensing data for actual drought in South Korea. Through the application of remote sensing data, it was judged that it would be possible to identify and understand various drought conditions occurring in all regions of South Korea, including unmeasured watersheds in the future.

• Journal of Applied Biological Chemistry
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• v.64 no.3
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• pp.299-307
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• 2021

Accumulation of amyloid beta (Aβ) and oxidative stress are the most common reason of Alzheimer's disease (AD). In the present study, we investigated the cognitive improvement effects of butanol (BuOH) fraction from Momordica charantia in Aβ_25-35-induced AD mouse model. To develop an AD mouse model, mice were received injection of Aβ_25-35, and then orally administered BuOH fraction from M. charantia at doses of 100 and 200 mg/kg/day during 14 days. In the T-maze and novel object recognition test, administration of BuOH fraction from M. charantia L. at doses of 100 and 200 mg/kg/day improved spatial ability and novel object recognition by increased explorations of novel route and new object. In addition, BuOH fraction of M. charantia-administered groups improved learning and memory abilities by decreased time to reach hidden platform in Morris water maze test. Oral administration of BuOH fraction from M. charantia significantly inhibited lipid peroxidation and nitric oxide levels in the brain, liver, and kidney compared with Aβ_25-35-induced control group. These results indicated that BuOH fraction of M. charantia improved Aβ_25-35-induced cognitive impairment by attenuating oxidative stress. Therefore, M. charantia could be useful for protection from Aβ_25-35-induced cognitive impairment.

• Journal of Climate Change Research
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• v.3 no.1
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• pp.1-12
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• 2012

In order to use as basic data of adaptation, this study focused on a 'Water management vulnerability estimation' in Korea. Vulnerability is estimated dividing into flood mitigation and water resource management. Temporal resolution is 2000 year and the future 2020 year, 2050 year, 2100 year via A1B scenario. Time series data was normalized. Then weight that is gotten through delphi investigation was multiplied. Vulnerability is calculated through this process. In flood mitigation vulnerability, it was estimated to adaptation ability affect relatively biggest influence. In future, some area of Gangwon-do was analyzed that the flood mitigation vulnerability increases. In water resource management, it was estimated to climate exposure affect relatively biggest influence. At 2020 yr, there is a trend toward increased in the Chungcheongbuk-do and DaeJeon, Daegu, some area of Gyeongsangnamdo. Because this study evaluate relative vulnerability of whole country and analyzed spatial distribution, when local government establishes climate change adaptation details enforcement countermeasure, this study can give help to grasp whether should invest more in some field.