• ALGAE
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• 제34권1호
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• pp.45-56
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• 2019

Ecklonia cava (EC) has been widely utilized as an ingredient in commercial products such as functional foods and cosmeceuticals. Recently it has been found that Sargassum horneri (SH) has been invading on Jeju Island coast area by its huge blooming. Moreover, both seaweeds are considering as important ingredients in traditional medicine specifically in East-Asian countries (China, Japan, and Korea). In the present study, we attempted to compare anti-inflammatory properties of 70% ethanolic extracts of EC (ECE), SH (SHE), and their different combinations on lipopolysaccharide (LPS)-activated RAW 264.7 cells. Results indicated that 8 : 2 combinations of ECE : SHE significantly inhibited LPS-activated inflammatory responses (cytokines, protein, and gene expression) in RAW 264.7 macrophage cells compared to the respective extracts and other combinations. The synergistic effect of ECE and SHE was found to be prominent than the effects of ECE or SHE alone. These observations provide useful information for the industrial formulation of functional materials (functional foods and cosmeceuticals) using these two particular seaweeds in Jeju Island of South Korea.

• 한국의료질향상학회지
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• 제27권1호
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• pp.20-25
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• 2021

Purpose: The ability to access clinical trials for cancer treatment is important. This study investigated whether regional differences exist in oncologic clinical trial protocols conducted in South Korea. Methods: Records of all approved oncologic clinical trials conducted in 2019 were downloaded from the Republic of Korea Ministry of Food and Drug Safety. The study covered Seoul, the capital area, other metropolitan cities, and provincial areas. Descriptive statistics summarized the distribution patterns of clinical trials by region. Results: A total of 202 oncologic clinical trials were conducted in 63 institutions in 2019. Of these protocols, 186 (92%) were available in Seoul, 120 (59%) in the capital area, 64 (32%) in metropolitan cities, and 66 (33%) in provincial areas. More regional differences in protocol availability were observed in domestic trials, investigator-initiated trials, phase 1 and 2 trials, and smaller-scale trials. Conclusion: Most oncologic clinical trials were conducted in medical institutions located in Seoul, with the rest conducted in the capital area, metropolitan cities, and provincial areas. The findings reveal clear differences in protocol availability between Seoul and the other regions. Measures designed to improve geographical access to oncologic clinical trials may be needed given their growing importance in cancer treatment.

• 식물병연구
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• 제27권1호
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• pp.24-31
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• 2021

Since the past few years, dimple rot has become one of the most serious diseases affecting Actinidia chinensis var. chinensis 'Zesy002' kiwifruit in Korea, leading to a low quality and subsequent losses of income. In the current study, the causal pathogen of side rot on 'Zesy002' kiwifruit was identified to be Botryosphaeria dothidea, a widespread pathogen that could penetrate the fruit directly without wounding. Diaporthe sp., another pathogen causing dimple rot, was isolated from infected kiwifruit. It was not able to infect fruits without wounding. Dimple-rot symptoms are known to be associated with other pathogens from the Pseudocercospora genus. In this study, B. dothidea was ratified as the causal disease agent in Jeju Island. To illustrate the pathogenicity of this fungus on 'Zesy002', further studies such as observation of infection structures of fungus may be needed.

• Child Health Nursing Research
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• 제28권3호
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• pp.208-217
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• 2022

Purpose: This study investigated childhood cancer survivors' behavior related to a healthy lifestyle during their survival period by comparing reports between childhood cancer survivors and their parents. Methods: In this comparative descriptive study, a survey was conducted with a 33-item questionnaire and one open-ended question about areas for improvement. The participants comprised 69 childhood cancer survivors and 69 of their parents, for a total of 138. Results: The total mean healthy lifestyle score, on a 4-point Likert scale, reported by childhood cancer survivors was 2.97, while that reported by their parents was 3.03. No significant differences in children's healthy lifestyles were found between childhood cancer survivors' and their parents' reports (t=0.86, p=.390). For the open-ended question, the main keywords based on the results of degree and eigenvector centrality were "exercise", "unbalanced diet", and "food". These keywords were present in both the children's and parents' responses. Conclusion: Obtaining information on childhood cancer survivors' healthy lifestyles based on reports from themselves and their parents provides meaningful insights into the improvement of health care management. The results of this study may be used to develop and plan healthy lifestyle standards to meet childhood cancer survivors' needs.

• 한국프랜차이즈경영연구
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• 제13권1호
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• pp.19-33
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• 2022

Purpose: Based on the resource-based view and the competitive advantage theory, the study views marketing capabilities (product, pricing, delivery/inventory, and promotional support) as sources of competitive advantage (differentiation advantage and low-cost advantage) and examines their impacts on competitive advantage, which in turn, will influence non-business and business performance. Research design, data and methodology: Data were collected from 149 representatives of franchising companies in South Korea and analyzed with SmartPLS 3.3.7. Results: First, promotional support and product have a significant impact on differentiation advantage. Second, pricing and promotional support have a significant impact on low-cost advantage. Third, differentiation advantage has an influence on non-financial and financial business performance. Fourth, low-cost advantage has an impact on non-financial performance but has no significant direct impact on financial performance. Fifth, non-financial performance is related to financial performance. Finally, the result of IPMA shows that importance and performance values of exogeneous variables are different depending on firm size. Conclusions: The findings suggest that franchisors should focus on different marketing capabilities depending on their strategic focus and objectives. Finally, the findings based on an IPMA suggest that small companies perceive low-cost advantage as important, while their counterparts do not. Several theoretical and managerial implications are offered.

• Nutrition Research and Practice
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• 제16권4호
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• pp.505-516
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• 2022

BACKGROUND/OBJECTIVES: The association between nutritional status and health-related quality of life (HRQoL) among patients with type 2 diabetes mellitus (T2DM) is not fully understood. This study was conducted to understand the role of nutritional status on HRQoL among people with and without T2DM. SUBJECTS/METHODS: Structured survey and direct measurement of anthropometric data were conducted among people with and without T2DM. Nutritional status was measured with Mini Nutritional Assessment tool and HRQoL was measured with a 36-item Short Form Healthy Survey. Data collection was conducted in Chuncheon, South Korea with 756 participants who are older than 40 yrs of age. RESULTS: This study found that overall HRQoL were significantly lower in people with T2DM than people without T2DM after controlling for key covariates. When stratified by nutritional status, a greater degree of negative impact of T2DM on overall physical HRQoL was observed among well-nourished or at risk of malnutrition, whereas significant and more evident negative impact of diabetes on overall psychological HRQoL was observed only among malnourished. CONCLUSIONS: The study results suggest the role of nutritional status among people with T2DM on overall, especially psychological aspects of HRQoL. Future longitudinal or intervention studies are warranted to test the impact of nutritional status on HRQoL among people with T2DM.

• The Plant Pathology Journal
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• 제38권5호
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• pp.513-521
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• 2022

Our study was carried out to determine the control efficacy of sodium hypochlorite (NaOCl) for violet root rot caused by Helicobasidium mompa in apple. The experiment was conducted in the farm located at Chungbuk province in South Korea from 2014 to 2016. When infected apple trees were treated at least two or three times with 31.25 and 62.5 ml/l available chlorine content in NaOCl, it greatly increased the rooting of rootstock, and restored the tree crown density by 44.4-60.5%. In addition, the number of commercial fruit setting was increased by 54.3-64.5%, and the total starch content in shoots was significantly higher than other non-treated apple trees. However, the untreated disease control and thiophanate-methyl WP treated trees showed the symptom of dieback. Therefore, our results indicate that the drenching treatment of NaOCl with 31.25-62.5 ml/l available chlorine content more than two times from late fall to early spring could effectively control the violet root rot and recover tree vigor up to 60%.

• 대한의생명과학회지
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• 제29권1호
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• pp.26-33
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• 2023

Ziziphus jujuba Mill. (ZJM), a traditional folk medicine and functional food in South Korea and China, has been reported to having pharmacological activities against anti-cancer, anti-oxidative, and anti-obesity. However, the effect of ZJM related to myoblast differentiation has not been known. In this study, we investigated the effects and mechanism of ZJM on myogenic differentiation of C2C12 cells. ZJM promotes myogenic differentiation and elevates the formation of multinucleated myotube compared to the control group. ZJM significantly increased the mRNA and protein expression of MyHC1, myogenin and MyoD in dose- and time-dependent manner. Interestingly, ZJM significantly inhibited the mRNA and protein expression of protein degradation markers, atrogin-1 and MuRF-1, in dose- and time-dependent manner. Taken together, our data suggest that ZJM is a potential functional candidate for muscle growth and strength by promoting myogenic differentiation.

• 운동영양학회지
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• 제13권3호
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• pp.185-192
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• 2009

The aim of this study was to examine the use of such dietary supplementation practices, opinions, taking period for dietary supplement, and among elite Judoists varying in age and gender. Subjects were recruited from Korea National Team Judoists in elite athlete training centers (Taenuing in Seoul, Korea and surrounding area), a total of 223 elite Judoists (2003y n=34, 2005y n=41, 2006y n=101, 2007y n=30, 2008y n=17). Data were collected from personal interviews with Judoists who participated at the Olympic games, Asian game and World Championship game since 2003-2008. Elite Judoists representing mean age of 2003y (men: 23.5±2.7, women: 22.6±2.4), 2005y (men: 23.4±2.6, women: 22.5±2.3), 2006y (men: 20.3±3.2, women: 21.9±2.4), 2007y (men: 25.3±2.6, women: 22.5±2.8) and 2008y (men: 23.9±3.9) completed a validated questionnaire assessing dietary supplementation practices and opinions. Older Judoists were significantly more likely to report greater dietary supplementation usage; to be advised by oneself; health food store and pharmacy retailers; to decrease taking period days per week and past 6 month. Relative to gender, significant differences were observed for the types of dietary supplementation reported; supplementation practice trend; reasons for dietary supplementation use.

• 농업과학연구
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• 제51권2호
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• pp.217-225
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• 2024

Timely and appropriate water supply to paddy fields is crucial for efficient agricultural water management. In South Korea, 17,240 agricultural reservoirs supply approximately 60% of the agricultural water and play a pivotal role in irrigation and drought mitigation. These reservoirs are managed by the Korea Rural Community Corporation (KRC), which oversees 3,411 reservoirs, and various local governments, which manage 13,829 locations. Guidelines from the Ministry of Agriculture, Food and Rural Affairs (MAFRA) mandate the installation and operation of water level measurement instruments. Currently, automated water level facilities are installed in 1,734 reservoirs and 1,880 irrigation canals, generating water level data at ten-minute intervals. In this study, a survey was conducted to enhance the management of agricultural reservoirs by integrating advanced information and communications technology (ICT) into existing automated water level gauge systems. We propose directions for enhancing the automated water level gauges in agricultural reservoirs. The findings would provide foundational data for stable and systematic management of these gauges.