• Title/Summary/Keyword: Sources of stress

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Role of dietary nucleotides to mitigate post-weaning stress in newly weaned pigs

  • Shin, Taeg Kyun;Wickramasuriya, Samiru Sudharaka;Cho, Hyun Min;Kim, Eunjoo;Kim, Younghwa;Park, Juncheol;Macelline, Shemil Priyan;Heo, Jung Min;Yi, Young-Joo
    • Korean Journal of Agricultural Science
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    • v.44 no.4
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    • pp.477-486
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    • 2017
  • This review provides an overview of dietary nucleotides as an alternative to in-feed antibiotics for weaning pigs. Dietary nucleotides are composed of DNA or RNA molecules and are normally contained in protein-rich feed ingredient, brewer's yeast, yeast extract, and milk. Weaning pigs are suffering from several stresses, such as environmental challenges (i.e. crowding, transportation, and feeding). Such stressors can damage the intestinal epithelium and cause an invasion by Escherichia coli, secondary inflammatory responses, and post weaning diarrhea. To overcome weaning disorder, people often use antibiotics which reduce symptoms and boost growth performance. However, since antibiotics were banned due to concerns of antibiotic resistant bacteria, researchers are studying alternative materials to antibiotics. Dietary nucleotides are one of the alternative materials for replacing antibiotics and can be used in abnormal conditions, such as weaning diarrhea, low digestibility, and disease condition. Nucleotides have substances that have important roles in cell division and cell growth, affecting growth performance, intestinal condition, and immunological effect at the weaning stage. However, nucleotides' composition is very different between sources and this aspect makes it difficult to utilize nucleotides at the weaning stage. Therefore, this review paper focuses on i) the characteristics and functions of dietary nucleotides and ii) the effect of dietary nucleotides on the growth performance and immune system of pigs.

STUDY ON EFFECTIVENESS OF NURSING PROFESSORS BY PERCEPTUAL ORIENTATION SCALE (지각향성검사에 의한 전문직 간호 교수들의 직업효율성에 관한 일 연구)

  • 김윤희
    • Journal of Korean Academy of Nursing
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    • v.3 no.3
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    • pp.27-35
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    • 1973
  • This thesis intends to make a study on the effectiveness of Nursing Professors through perceptual psychological approach. Purpose of the Study Researches have been made relating teacher′s effectiveness measurement. However, they share a common defect that they have been done on the basis of superficial aspects of the problems aspects that can bi measured by general objective survey only, but this study is designed "to understand his behavior in terms of a human behaving and of a self as an instrument"-principle, based upon the Perceptual Psychology which puts more stress on the inner perception than on the external one. Method of the Study This thesis is based chiefly on the two sources : "Perceptual Orientation Scale"(Chunghoon Choy, 1971) which has been standardized on the basis of perceptual psychology and the question acres made by the researcher of this thesis and given to the 34 Nursing Professors in seoul and other country. Result of the Study The method of data operation by Pearson "r" asserts that there were distinct deep relation Between Perceptual orientation and fellow′s estimate, while a little relation among the estimate of a-administration, educational backgrounds and occupations but no relations the status of experiences. It can be concluded that the estimates between fellows working at "the same fields" have kept deep relations together on perceptual orientation which resulted from finding out a useful method to measure occupational effectiveness according to the perceptual field. Conclusion of the Study The personnel administration has been managed according to external flatus and not positive operation: on the other hand, this study holds, It shall be operated in accordance with the estimates by fellow, the "Preceptual Orientation Scale" for more positive ability. The study requires the following researches on the devoted professional occupations, such as medical doctors, teachers, nurses, etc. for the purpose of increasing their occupational effectiveness more scientifically.

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EROD and TOSC Assays Using Sentinel Fish Species as Tools for Assessing Physiological Level of Aquatic Ecosystem Health: Case Study

  • Lee, Jae-Hoon;Kim, Hyun-Mac;Jang, Seong-Hui;Yun, Kang-Uk;Kim, Sang-Kyum;An, Kwang-Guk
    • Korean Journal of Ecology and Environment
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    • v.41 no.4
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    • pp.541-546
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    • 2008
  • The purpose of this study was to evaluate ecosystem health effect in the physiological levels, based on ethoxyresorufin-O-deethylase (EROD) and total oxyradical scavenging capacity (TOSC) assays using sentinel fish species. We collected fish samples of Zacco platypus in May 2008 from 3 sampling sites including upstream, midstream, and downstream of the Gap Stream. EROD activity was averaged 4.54 in the downstream, 2.7 fold higher than upstream and indicated that stream condition was degraded along with longitudinal gradient from up to downstream. Downstream, especially was significantly increased (p < 0.01) so that indicated various pollutants including nutrient enrichment and toxicant exposure from the point sources, wastewater treatment plant and industrial complex may impact to the stream condition. In the mean time, TOSC assays showed higher in the midstream than other sites, but the values were not significant, compared to the previous report on oxidative stress. Overall results indicated that our approaches applying two biomarkers can be effectively used for diagnosis of the physiological levels in an integrative stream health assessments and can be applied as useful pre-warning techniques as a biochemical alarm system of organic pollutions.

Spark Plasma Sintering and Ultra-Precision Machining Characteristics of SiC

  • Son, Hyeon-Taek;Kim, Dae-Guen;Park, Soon-Sub;Lee, Jong-Hyeon
    • Korean Journal of Materials Research
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    • v.20 no.11
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    • pp.559-569
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    • 2010
  • The liquid-phase sintering method was used to prepare a glass lens forming core composed of SiC-$Al_2O_3-Y_2O_3$. Spark plasma sintering was used to obtain dense sintered bodies. The sintering characteristics of different SiC sources and compositions of additives were studied. Results revealed that, owing to its initial larger surface area, $\alpha$-SiC offers sinterability that is superior to that of $\beta$-SiC. A maximum density of $3.32\;g/cm^3$ (theoretical density [TD] of 99.7%) was obtained in $\alpha$-SiC-10 wt% ($6Al_2O_3-4Y_2O_3$) sintered at $1850^{\circ}C$ without high-energy ball milling. The maximum hardness and compression stress of the sintered body reached 2870 Hv and 1110 MPa, respectively. The optimum ultra-precision machining parameters were a grinding speed of 1243 m/min, work spindle rotation rate of 100 rpm, feed rate of 0.5 mm/min, and depth of cut of $0.2\;{\mu}m$. The surface roughnesses of the thus prepared final products were Ra = 4.3 nm and Rt = 55.3 nm for the aspheric lens forming core and Ra = 4.4 nm and Rt = 41.9 for the spherical lens forming core. These values were found to be sufficiently low, and the cores showed good compatibility between SiC and the diamond-like carbon (DLC) coating material. Thus, these glass lens forming cores have great potential for application in the lens industry.

Cabbage (Brassica oleracea L. var. capitata) Phytochemicals with Antioxidant and Anti-inflammatory Potential

  • Rokayya, Sami;Li, Chun-Juan;Zhao, Yan;Li, Ying;Sun, Chang-Hao
    • Asian Pacific Journal of Cancer Prevention
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    • v.14 no.11
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    • pp.6657-6662
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    • 2013
  • Background: The objective of this study was to investigate antioxidant and anti-inflammatory activity of cabbage phytochemicals. Materials and Methods: Color coordinates were evaluated by colorimetry, and the antioxidant and anti-inflammatory activities were analyzed by spectrophotometer for some common cabbage varieties. Results: Red heads had the highest total antioxidant contents followed by Savoy, Chinese and green heads. The Chinese variety had the highest ABTS (2,2-azino-di-(3-ethylbenzthiazoline-sulfonic acid) antioxidant activity, was 5.72 ${\mu}mol$ TE/g fw (Trolox equivalent). The green variety had the highest DPPH (free radical scavenging activity) antioxidant activity, which was 91.2 ${\mu}mol$ TE/g fw. The red variety had the highest FRAP (ferric reducing antioxidant power) antioxidant activity, which was 80.8 ${\mu}mol$ TE/g fw. The total phenol amounts were 17.2-32.6 mM trolox equivalent antioxidant capacity (TEAC) and the total flavonoid amounts were 40.0-74.2 mg quercetin per gram. Methanolic extracts of different cabbage heads showed different anti-inflammatory activity values. Chinese, Savoy and green heads had the highest anti-inflammatory activity, while red heads had the lowest. Conclusions: The results suggest that these varieties of cabbage heads could contribute as sources of important antioxidant and anti-inflammatory related to the prevention of chronic diseases associated to oxidative stress, such as in cancer and coronary artery disease.

Evaluation of Mechanical Properties of Molding Materials Recycled Using Film Packaging Wastes (폐필름 포장재 재활용 성형재료의 역학적 특성 평가)

  • Kwon, Seung-Jun;Lim, Hee-Seob;Yang, Keun-Hyeok;Yoon, Hyun-Sub
    • Journal of the Korean Recycled Construction Resources Institute
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    • v.6 no.4
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    • pp.342-348
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    • 2018
  • The present study examined the various strength and deformation performances of molding materials recycled using film packaging wastes to ascertain the their applicability to secondary products in construction industries. The stress-strain relationships of molding materials were measured under compression, tension, and flexure in accordance with the ASTM procedure. The measured mechanical properties of recycled molding materials were comparable to typical ranges observed in low-density polyethylene and/or high-density polyethylene. However, to stabilize the properties of the molding materials, further management systems are required as follows: 1) evaluation of mechanical properties of materials with respect to various mixing proportions of waste ingredients; 2) estimation of the effect of foreign substance and moisture contents on the mechanical properties; and 3) establishment of comprehensive database including various sources such as manufacture process including applied pressure to produce the molding materials, and collection region and time of wastes.

The Influence of Sense of Self-efficiency in the Course of the Decision for Clothing Purchase (자기효능감이 의복구매의사결정과정에 미치는 영향)

  • 유태순;김성희
    • Journal of the Korean Society of Costume
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    • v.51 no.2
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    • pp.105-120
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    • 2001
  • The purpose of this study is to identify the relationship of self-efficacy, which is a kind of the self concept about one's own ability, to the decision-making process, which is the key part of consumer behavior. The subjects in this study were 985 male and female undergraduates of a university located in the city of Kyongsan, the north Kyongsang province. The collected data were statistically processed by MANOVA and ANOVA. For post test, Scaffle and $\chi$$^2$-test were employed. The followings are findings of this study : 1. Concerning incentive to buying, the group having the weaker general self-efficacy is stimulated more highly by the incentives of self-display, fashion pursuit and economic utility than the group having the stronger general self-efficacy does. 2. Regarding information sources. the factor of observation is frequently used by the group having the weaker general and social self-efficacies more than the group having the stronger general and social self-efficacies. 3. As to the evaluative criteria of clothes, the group having the stronger general and social self-efficacies put a higher value on functional and economical points than the group having the weaker general and social self-efficacies does. 4. As for the evaluative criteria of store the group having the stronger general self-efficacy lays stress on store atmosphere, store attributes and convenient shopping condition, while the group having the weaker general self-efficacy puts emphasis on brand and fashion. 5. In buying apparels, the group having the stronger general and social self-efficacies makes more planned purchase.

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Proteomic Analysis of Fructophilic Properties of Osmotolerant Candida magnoliae

  • Yu, Ji-Hee;Lee, Dae-Hee;Park, Yong-Cheol;Lee, Mi-Gi;Kim, Dae-Ok;Ryu, Yeon-Woo;Seo, Jin-Ho
    • Journal of Microbiology and Biotechnology
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    • v.18 no.2
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    • pp.248-254
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    • 2008
  • Candida magnoliae, an osmotolerant and erythritol producing yeast, prefers D-fructose to D-glucose as carbon sources. For the investigation of the fructophilic characteristics with respect to sugar transportation, a sequential extraction method using various detergents and ultracentrifugation was developed to isolate cellular membrane proteins in C. magnoliae. Immunoblot analysis with the Pma1 antibody and two-dimensional electrophoresis analysis coupled with MS showed that the fraction II was enriched with membrane proteins. Eighteen proteins out of 36 spots were identified as membrane or membrane-associated proteins involved in sugar uptake, stress response, carbon metabolism, and so on. Among them, three proteins were significantly upregulated under the fructose supplying conditions. The hexose transporter was highly homologous to Ght6p in Schizosaccharomyces pombe, which was known as a predominant transporter for the fructose uptake of S. pombe because it exhibited higher affinity to D-fructose than D-glucose. The physicochemical properties of the ATP-binding cassette transporter and inorganic transporter explained their direct or indirect associations with the fructophilic behavior of C. magnoliae. The identification and characterization of membrane proteins involved in sugar uptake might contribute to the elucidation of the selective utilization of fructose to glucose by C. magnoliae at a molecular level.

Natural Compounds with Antioxidant Activity: Recent Findings from Studies on Medicinal Plants

  • Na, Min-Kyun;Thuong, Phuong Thien;Bae, Ki-Hwan
    • Natural Product Sciences
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    • v.17 no.2
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    • pp.65-79
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    • 2011
  • Reactive oxygen species potentially cause damage to cellular components including lipids, protein and DNA; this oxidative damage plays a key role in the pathogenesis of neurodegenerative disease, cardiovascular disease, metabolic disease and cancer. On the basis of the oxidative stress hypothesis, a number of studies have been performed to search for an efficient and safe antioxidant. Although in vitro studies have provided promising results, only a limited number of natural and synthetic antioxidants have been developed for clinical application due to their low efficacy and side-effects. Thus, the discovery of new antioxidants with marked efficacy and safety has attracted worldwide attention in recent decades. Since plants are recognized as important sources of natural antioxidants, our research has focused on the discovery of new naturally occurring antioxidants from medicinal plants. The purpose of this review is to open a new prospect in the field of search for natural antioxidants from medicinal plants by summarizing our recent findings. Using in vitro bioassay systems such as 2,2-diphenyl-1-picrylhydrazyl, superoxide radical scavenging tests and lipid peroxidation models, we have tested over than 350 species of medicinal plants for their antioxidant activity and selected several of them for further investigation. During the research on the discovery of effective natural antioxidants from the medicinal plants selected, we have isolated several new and known antioxidant compounds that include stilbene glycosides, phenolic glycosides, flavonoids, oligostilbenes, and coumarins. Our results suggest that the presence of antioxidant compounds in the medicinal plants might be associated with the traditional use to treat inflammation, cardiovascular disease and various chronic diseases.

Evaluation of Effective MMP Inhibitors from Eight Different Brown Algae in Human Fibrosarcoma HT1080 Cells

  • Bae, Min Joo;Karadeniz, Fatih;Ahn, Byul-Nim;Kong, Chang-Suk
    • Preventive Nutrition and Food Science
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    • v.20 no.3
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    • pp.153-161
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    • 2015
  • Matrix metalloproteinases (MMPs) are crucial extracellular matrices degrading enzymes that have important roles in metastasis of cancer progression as well as other significant conditions such as oxidative stress and hepatic fibrosis. Marine plants are on the rise for their potential to provide natural products that exhibit remarkable health benefits. In this context, brown algae species have been of much interest in the pharmaceutical field with reported instances of isolation of bioactive compounds against tumor growth and MMP activity. In this study, eight different brown algae species were harvested, and their extracts were compared in regard to their anti-MMP effects. According to gelatin zymography results, Ecklonia cava, Ecklonia bicyclis, and Ishige okamurae showed higher inhibitory effects than the other samples on MMP-2 and -9 activity at the concentrations of 10, 50, and $100{\mu}g/mL$. However, only I. okamurae was able to regulate the MMP activity through the expression of MMP and tissue inhibitor of MMP observed by mRNA levels. Overall, brown algae species showed to be good sources for anti-MMP agents, while I. okamurae needs to be further studied for its potential to yield pharmaceutical molecules that can regulate MMP-activity through cellular pathways as well as enzymatic inhibition.