• Natural Product Sciences
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• v.25 no.4
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• pp.334-340
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• 2019

Cuscuta chinensis Lam. and Cuscuta japonica Choisy are parasitic plants. C. chinensis seeds were traditionally used for treatment of kidney and liver deficiencies. C. japonica seeds were used as tonic medicine to improve liver function and strengthen kidneys, treatment of high blood pressure, chronic diarrhea, and sore eyes. Cuscutae Semen are seeds of only C. chinensis in Korean Herbal Pharmacopoeia (K.H.P.). The developed HPLC-PDA method easily, accurately, and sensitively quantified using eight marker compounds [hyperoside (1), astragalin, (2), quercetin (3), kaempferol (4), chlorogenic acid (5), 3,4-di-O-caffeoylquinic acid (6), 1,5-di-O-caffeoylquinic acid (7), and 4,5-di-O-caffeoylquinic acid (8)]. In addition, the method may be used to distinguish seeds between C. chinensis Lam. and C. japonica Choisy. Furthermore, the result from the current study was applied to clarify samples between steam processed and unprocessed samples of C. chinensis by pattern analysis.

• The Journal of Korean Medicine Ophthalmology and Otolaryngology and Dermatology
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• v.29 no.4
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• pp.182-188
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• 2016

Objectives : The purpose of this study is to report the effect of low level laser therapy and acupuncture on hair loss. Methods : The patient with alopecia caused by bed sore and alopecia areata was treated with 29 times of laser therapy, acupuncture and took herbal medicine during about 3 months. The treatment effect was evaluated by standardized photography. Results : Hair loss had shown a marked improvement. Entire scalp had been replaced with new hairs. Conclusions : LLLT(low level laser therapy) is effective method for treating alopecia. It can shorten the length of treatment of alopecia.

• Journal of Environmental Health Sciences
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• v.24 no.2
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• pp.80-87
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• 1998

To evaluate the effects on health by exposure to low dose organic solvents, the author analyzed the air concentration of mixed organic solvents (toluene, xylene, butylacetate) at worker's breathing zone during painting, some laboratory findings of blood (WBC, RBC, Hb, Hct, SGOT, SGPT, TC, TG, HDL-C, LDL-C, IgG, IgM, IgA and IgE) and urine (hippuric acid, urinary protein, urobilinogen), surveyed the subjective symptoms those were obtained from 35 male workers exposed to mixed organic solvents, and 25 male workers not exposed to organic solvents who worked in car repair workshops in Taejon area from December 1, 1995, to February 29, 1996. The results were as follows: 1. The mean concentration of urinary hippuric acid of car painting worker group (organic solvent exposure group) was 0.76$\pm$ 0.21 g/l, which is significantly higher than that of non-exposed group. 2. In hematologic findings, the values of RBC, TC, LDL-C, IgG and IgE in the exposure group were significantly lower than those of the nonexposed group, but SGOT and SGPT in the exposure group were significantly higher than those of the non-exposed group. 3. Urinary hippuric acid levels showed positively correlated with toluene, urobilinogen and HDL-C levels, but those were negatively correlated with RBC, LDL-C, IgM levels. 4. Rates of the subjective symptoms such as "dizziness", "appetite loss", "weight loss", "palpitation", "chest tightness", "sore throat and eye discomfort", "tingling sense and acrodynia", "illusion or hallucination" and "decreaased motor power" were significantly higher in the exposure group than those of the non-exposed group.

• Asian Oncology Nursing
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• v.2 no.1
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• pp.72-82
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• 2002

Purpose : To observe changes in side effects and fatigue of the cancer patients receiving radiation therapy on the head/neck and the chest over a period from the start to the end of the therapy, and to analyze correlation between side effects and fatigue. Method : Twenty seven patients receiving radiation therapy 5 days per week for longer than 6 weeks participated in the present study. Fatigue was measured for when healthy, before-, and after-therapy. Side effects was surveyed by structured questionnaire on the last day of each therapy. Result : The results of this study were as follows. 1. Major side effects of the head/neck patients were skin irritation, change of taste, sore throat and xerostomia, while the chest patients experienced fatigue, skin irritation, anorexia, difficulty swallowing and cough increased with therapy. 2. Although fatigue was significantly changed for when healthy and before-therapy (F=60.25, p <.05) and also for before- and after-therapy, no statistical significance was demonstrated in fatigue of both the chest head/neck patients (p> .05). 3. Fatigue and side effects showed high correlation form the 4-th week with after the therapy Conclusion : The present results could be of great use to develop systematic intervention technique, leading to practical help for patients, since side effects and fatigue change to a large degree depending on the disease and the timing and technique of the therapy.

• The Journal of Korean Medicine
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• v.30 no.4
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• pp.37-46
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• 2009

Objectives: The purpose of this study was to investigate the external application of paste preparation recorded in the Annals of the Chosun Dynasty (朝鮮王朝實錄) and to clarify the significance of modern use of plaster therapy. Methods: Of many paste preparations, records of All-applying ointment (萬應膏), One-great ointment (太一膏), Pain-relieving plaster (救苦膏), and Pus-promoting powder (促膿膏) were especially examined from the Annals of the Chosun Dynasty. Other medical records regarding how these preparations were passed onto later generations were also studied. Results: According to the records from the Annals of the Chosun Dynasty, paste preparations were mainly used to cure abscess and sore, partly to treat pain diseases. From other medical documents, it could be found that these preparations were continuously used in subsequent eras. Conclusions: From these records, the level and features of Chosun Dynasty medicine could be speculated. It is necessary to find and restore effective paste preparations in Traditional Korean Medicine to use for treating disease today. Therefore, records from the Annals of the Chosun Dynasty are important and meaningful materials.

• The Journal of Pediatrics of Korean Medicine
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• v.17 no.2
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• pp.27-35
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• 2003

Objective : About 5% of children suffer from convulsive disease before they grow up. Among the convulsive disease, epilepsy means the chronic and relapsed nervous disorder. The etiologic factors of epilepsy are very various. But about 75% of cases are idiopathic, in other words, we cannot find the origin of the disease. Method : We report on 8-year-old male patient with idiopathic epilepsy. We treated him with Hyoungbangdojeok-San and acupuncture. Results : After treatments, the symptoms(convulsion, cough, sputum, constipation, and sore throat) are improved. Conclusion : We had good effects in oriental medical treatment on Idiopathic Epilepsy. And the more study about this disease is needed.

• The Journal of Internal Korean Medicine
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• v.31 no.2
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• pp.388-394
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• 2010

Objectives : This study reports two cases of grade four pressure ulcer patients mainly treated by pharmacopuncture Soyeom and Taklisodok-eum. Methods : Two patients with grade four pressure ulcers at the oriental medicine hospital of Woosuk University were treated by pharmacopuncture Soyeom and herbal medicine Taklisodok-eum. Soyeom was treated once a day and Taklisodok-eum was given three times a day. We then observed the patients' appearances of pressure ulcer and changes of blood test results. Results and Conclusions : After ten days or three months each, wound sizes were reduced, tissue regeneration was accelerated and blood tests were improved. In conclusion, it is our belief that pharmacopuncture and herb medicine are effective to treat grade four pressure ulcers, and future studies will be required to ascertain this method on grade four pressure ulcers.

• Korean Journal of Pharmacognosy
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• v.33 no.1 s.128
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• pp.29-34
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• 2002

Albizzia julibrissin belonging to the family Leguminosae has been used for the treatment of contusion, sore throat, amnesia, and insomnia in Oriental traditional medicine. The water extract of A. julibrissin induced apoptosis in Jurkat T-acute lymphoblastic leukemia (ALL) cells as measured by cell morphology. The capability of this herb medicine to induce apoptosis was associated with proteolytic cleavage of specific target protein such as beta-catenin protein suggesting the possible involvement of caspases. The purpose of the present study is also to investigate the effect of A. julibrissin on cell cycle progression. Our results showed that GI checkpoint related gene products (cyclin D1, cyclin dependent kinase 4, retinoblastoma, E2F1) were decreased in their protein levels in a dose-dependent manners after treatment of the extract. These results indicate that the increase of apoptotic cell death by A. julibrissin may be due to the inhibition of cell cycle progression in wild type p53-lacking Jurkat cells.

• Archives of Plastic Surgery
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• v.39 no.4
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• pp.412-416
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• 2012

Background Even though the quality of medical and surgical care has improved remarkably over time, iatrogenic injuries that require surgical treatment including injuries caused by cast and elastic bandage pressure, extravasation, and dopamine-induced ischemia still frequently occur. The goal of this study was to estimate the incidence and analyze the distribution of iatrogenic injuries referred to our department. Methods A retrospective clinical review was performed from April 2006 to November 2010. In total, 196 patients (116 females and 80 males) were referred to the plastic surgery department for the treatment of iatrogenic injuries. We analyzed the types and anatomic locations of iatrogenic complications, along with therapeutic results. Results An extravasation injury (65 cases, 37.4%) was the most common iatrogenic complication in our study sample, followed by splint-induced skin ulceration, dopamine-induced necrosis, prefabricated pneumatic walking brace-related wounds and elastic bandage-induced wounds. Among these, prefabricated pneumatic walking brace-related complication incidence increased the most during the 5-year study period. Conclusions The awareness of the very common iatrogenic complications and its causes may allow physicians to reduce their occurrence and allow for earlier detection and referral to a plastic surgeon. We believe this is the first study to analyze iatrogenic complications referred to a plastic surgery department in a hospital unit.

• Journal of Physiology & Pathology in Korean Medicine
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• v.18 no.1
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• pp.285-288
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• 2004

This study was designed to report the clinical effects of Hyunhwang-haedok-tang on patients who have suffered from acute tonsillitis. Patients complained of fever, sore throat, swallowing difficulty, headache, cough. We give a diagnosis of acute tonsillitis. Therefore, we treated patients with oriental medicine, especially Hyunhwang-haedok-tang, and found that those symptoms and signs were improved by VAS, which is visual analogue scale. Through this study, Hyunhwang-haedok-tang on patients who have suffered from acute tonsillitis, proved to be effective.