• Title/Summary/Keyword: Song Ku-bong

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The Significance of Ku70 Expression in Patients with Nasopharyngeal Carcinoma (비인강암에서 방사선치료의 예측인자로써 Ku70 발현의 의의)

  • Song Si Yeol;Lee Sang-wook;Yu Eunsil;Cho Kyung-Ja;Park Jin-hong;Kim Sang Yoon;Nam Soon Yuhl;Lee Bong-Jae;Kim Sung Bae;Choi Seung-Ho;Ahn Seung Do;Shin Seong Soo;Choi Eun Kyung
    • Radiation Oncology Journal
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    • v.23 no.1
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    • pp.1-8
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    • 2005
  • Purpose : The objective of this study was to determine whether the expressions of the two components of DNA-dependent protein kinase, Ku70 and DNA-PKcs, influence the response to radiotherapy (RT) and outcome of treatment of non-disseminated nasopharyngeal carcinoma (NPC) in patients who received definitive RT. Materials and Methods : Sixty-six patients with NPC who were treated with radiotherapy alone or with concurrent chemotherapy between June 1995 and December 2001 were divided into groups based on the levels of immunoreactivity for Ku70 and DNA-PKcs in pretreatment biopsy specimens. The over-expression of Ku70 or DNA-PKcs groups Included patients whose biopsy specimens showed at least 50% immunopositive tumor cells; patients in which less than 50% of the tumor cells in the biopsy tissues were immunopositive were placed in the low Ku70 and DNA-PKcs groups. The immunoreactivities for Ku70 and DNA-PKcs were retrospectively compared with the sensitivity of the tumor to radiation and the patterns of therapy failure. Univariate analyses were peformed to determine the prognostic factors that influenced locoregional control of NPC. Results : The five-year locoregional control rate was significantly higher in the low Ku70 group (Ku(-)) (85%) than in the high Ku70 group (Ku(+)) (42%) (p=0.0042). However, there were no differences in the metastases-free survival rates between the two groups (Ku70 (+), 82%; Ku70 (-), 78%; p=0.8672). Univariate analysis indicated that the over-expression of Ku70 surpassed other well-known predictive clinocopathologic parameters as an Independent prognostic factor for locoregionai control. Eighteen of 22 patients who had locoregional recurrences of the tumor displayed an over-expression of Ku70. No significant association was found between the level of DNA-PKcs expression and the clinical outcome. Conclusion : Our data suggest that the level of Ku70 expression can be used as a molecular marker to predict the response to RT and the locoregional control after RT and concurrent chemotherapy in patients with non-disseminated NPC.

A Implementation of TRS Application System for Power Utility Quick Repair (전력설비 기동보수를 위한 TRS 응용시스템 구현)

  • Song, Jae-Ju;Shin, Jin-Ho;Lee, Jung-Li;Yi, Bong-Jae;Cho, Sun-Ku
    • Proceedings of the KIEE Conference
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    • 2005.07d
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    • pp.2939-2941
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    • 2005
  • 한전에서 핵심사업으로 구축된 신 배전정보 시스템은 전반적인 배전업무 수행은 물론, 전기고장신고 콜센터를 통한 복구처리 등 전력설비 기동보수와 같은 대고객업무에도 효과적으로 활용하고 있다. 하지만 콜센타에 의해 접수된 전기고장 정보와 이동중인 기동 보수차량 간에 시스템적인 연계가 불가능하여 이미 구축된 고장위치 도면정보, 설비속성 정보 등과 같이 복구에 필요한 정보를 현장에서의 활용이 어려운 실정이었다. 이러한 배경에서 기동보수 차량의 위치를 모바일 환경에서 상시 파악하여 고장지점으로 신속히 출동시키게 하고, 현장에서는 고장접수정보와 계통정보 등을 제공하여 고장설비를 신속 복구함으로서 고객서비스의 질을 높이기 위한 TRS 응용 시스템를 구현하고 그 결과를 기술하였다.

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Implementation of Real-time Power Facility Monitoring System Using WSN (무선 센서 네트워크 기술을 이용한 전력 설비 실시간 감시 시스템 구현)

  • Kim, Young-Il;Cho, Seon-Ku;Yi, Bong-Jae;Song, Jae-Ju;Shin, Jin-Ho
    • Proceedings of the KIEE Conference
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    • 2006.10c
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    • pp.488-490
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    • 2006
  • In the electric power industry, It is important that the supply of energy must always be guaranteed. To satisfy these requirements, various forms of technologies are needed, such as RFID tag, reader, sensor network, middleware and so on. WSN (Wireless Sensor Network) technologies of the electric power industry are in the early stage and there is no clear guideline for developing electric facility management system using WSN. Relevant experience is limited, the challenge will be to derive requirement from business practice and to determine whether it is possible or not. To explore this issue, we focus on researching and field test of prototype system in Korea Electric Power Corporation (KEPCO). In this paper we describe requirement from power industry. And we introduce design and implementation of the power facility monitoring system.

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A Development of Wireless Monitoring System for Effective Surface Temperature Monitoring of Cable Joint (효율적인 전력케이블 접속함의 표면온도감시를 위한 무선감시시스템 개발)

  • Kim, Young-Il;Song, Jae-Ju;Shin, Jin-Ho;Yi, Bong-Jae;Cho, Seon-Ku
    • Proceedings of the KIEE Conference
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    • 2007.07a
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    • pp.1854-1855
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    • 2007
  • 계측 및 정보기술의 발달로 지하전력구 내에 설치된 송전 케이블에 대한 감시를 위해 다양한 기술을 활용하여 감시시스템을 구축하고자 하는 연구가 진행되고 있다. 대표적인 방식으로 광섬유를 이용하여 전력케이블의 온도를 측정하는 방식이 있으며 이러한 방식의 궁극적인 목적은 전력케이블의 온도를 측정하고 과열개소를 실시간으로 파악하는 것이다. 그러나 이러한 시스템을 구축하기 위해서는 케이블을 설치하고 고가의 감시 장치를 설치, 운영해야 하는 어려움이 있다. 본 연구에서는 설치비용을 최소화할 수 있도록 무선 통신을 기반으로 하는 감시시스템을 고려하였다. 본 연구에서는 저가형 저전력 무선센서노드를 이용하여 케이블의 표면온도를 측정하고 이를 감시할 수 있는 무선감시시스템을 개발하였다.

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Development of Evaluation Indicators and Analysis of Usability on Learning with a Robot for the Elderly - the case of Content using the Humanoid Robot 'LiKU' (장노년층을 위한 로봇 활용 교육의 사용성 평가 지표 개발 및 평가 분석 - 휴머노이드 로봇 'LiKU'의 콘텐츠 사례)

  • Sin, Eun-joo;Song, Joo-bong;Lim, Soon-bum
    • The Journal of the Korea Contents Association
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    • v.21 no.11
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    • pp.56-63
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    • 2021
  • To solve the digital divide of the elderly, various institutions are educating how to use various smart devices for the elderly. However, it cannot be expected to have a great effect due to the disadvantages of instructor-to-face education and the learning characteristics of the elderly. Accordingly, educational contents using digital devices using robots for the elderly were developed. In this study, Evaluation Indicators were developed to evaluate the usability of digital education using robots. Also, by using usability evaluation based on the developed Evaluation Indicators, we tried to verify the usability of education using robots and to confirm the possibility of expanding the application area. In order to successfully apply the developing robot technology to various fields, it is essential to verify the usability of contents using robots, and this study on Evaluation Indicators and Evaluation methods is expected to serve as a foundation.

A Development of Surface Temperature Monitoring System for Underground Tunnel Cable Joint using Wireless Sensor (무선센서를 이용한 지하전력구의 케이블 접속함 표면온도감시시스템 개발)

  • Kim, Young-Il;Song, Jae-Ju;Shin, Jin-Ho;Yi, Bong-Jae;Cho, Seon-Ku
    • The Transactions of The Korean Institute of Electrical Engineers
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    • v.56 no.11
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    • pp.1879-1884
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    • 2007
  • In the electric power industry, it is important that the supply of energy must be guaranteed. Many power utilities control and supervise the transmission line to avoid power failures. In case of underground tunnel, some troubles are reported in cable joint. To stabilize the power, it is needed to monitor the cable joint. Many researches of cable joint monitoring have been going on by partial discharge measurement and temperature measurement using optical cable. These methods need much cost to install and maintain, so it is only used in critical transmission line. In this research, we use wireless sensor technology, because of its low cost and easy installation. We develop the temperature monitoring system for cable joint. Temperature sensor is installed on the surface of cable joint and sends data to server through router node using wireless network. Generally Ad hoc routing is searched in wireless network. However, in this research, we design the static linear routing mechanism, which is suitable for electric power line monitoring and analyze the life time of the sensor node by measuring the amount of the battery consumption.

A Study on the Electric Pole Positioning Technology for Power Distribution GIS using National Geographic Digital Map (국가기본도를 사용하는 배전지리정보시스템에서의 전주위치 보정기법 연구)

  • Yi, Bong-Jae;Song, Jae-Ju;Shin, Jin-Ho;Cho, Seon-Ku
    • Proceedings of the KIEE Conference
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    • 2001.07d
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    • pp.2708-2710
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    • 2001
  • 한전에서는 판매업무의 혁신을 기하기 위하여 지리정보시스템(GIS)을 운영기반으로 하는 신배전정보시스템(NDIS : New Distribution Information System) 구축사업을 적극적으로 추진하여 현재 일부 지사 지점에서 시범운영중에 있으며, 향후 전국적인 운영확산이 예정되어 있다. NDIS에서는 국가기본도를 GIS의 기초도면으로 활용하고 있으나 DB구축시 기존 설비도면과의 상대위치오차가 발생되고, 설비가 누락 또는 오분류되어 있는 경우가 있어 이를 보정하는데 많은 노력이 드는 실정이다. 국가기본도 사용을 전제할 때 이러한 문제점은 피할 수 없는 현상이며, 한전에서는 이를 보다 효과적으로 해결하고자 배전설비에서 위치의 기준이 되는 전주를 중심으로 기초도면 변경에 따른 설비도면 보정기법연구와 시스템 개발을 수행하였다. 본고에서는 한전에서의 설비도 위치보정 적용환경과 함께 연구개발된 내용을 소개하고자 한다.

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Functional Properties of Sodium Caseinate Hydrolysates with Angiotensin-I-Converting Enzyme (ACE) Inhibitory Activity: A Review (Angiotensin-I Converting Enzyme(ACE) 저해효과를 갖는 Sodium Caseinate 가수분해물의 기능적 특성에 관한 연구: 총설)

  • Lee, Keon-Bong;Baick, Seung-Chun;Chon, Jung-Whan;Kim, Hyun-Sook;Song, Kwang-Young;Seo, Kun-Ho
    • Journal of Dairy Science and Biotechnology
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    • v.32 no.1
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    • pp.7-16
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    • 2014
  • Angiotensin-I-converting enzyme (ACE) inhibitory peptides have functional and potential properties of casein hydrolysates that are used in the development of food ingredients and anti-hypertensive hydrolysates derived from sodium caseinate enzymatic hydrolysates. Sodium caseinate could be treated by various kinds of commercial proteases, and then could be treated with the enzyme combination. Ultrafiltration treatment can be used to generate hydrolysates that can be used to determine ACE inhibitory activity. In general, hydrolysate quality can be evaluated by changes in hydrolysis characteristics, ACE inhibitory activity, as well as functional properties such as solubility, foam capacity, cytotoxicity, free radical-scavenging effects, and sensory evaluation. In this review, we present an overview of the ACE inhibitory peptides obtained by performing enzymatic hydrolysis on various sources to identify food ingredients and functional foods that reduce hypertension.

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