• 대한한의학회지
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• 제19권2호
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• pp.137-152
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• 1998

Acute complications of diabetes mellitus were diminished after Banting and Best discovered insulin. But chronic complications of diabetes mellitus have been increased. The main complications of diabetes mellitus are diabetic retinopathy, diabetic nephropathy, diabetic neuropathy, diabetic foot lesion and macrovascular complication. These complications can result in renal failure, loss of sight, cerebral infarction and myocardial infarction. So it is very difficult to treat the complications of diabetes mellitus. In oriental medicine, the transformations(傳變症) of Sogal(消渴) are edema, carbuncle, loss of sight and so on. The comparative study between the trcmsformations(傳變症) of SogaI(消渴) and the complications of diabetes mellitus has come to the following conclusions. 1. In oriental medicine, diabetic retinopathy was expessed as loss of sight and the treament of diabetic retinopathy should be started at an early stage, to prevent vitreous hemorrhage and traction retinal detachment. 2. In oriental medicine. diabetic nephropathy was expressed as edema and the treatment should be started at an early stage of renal injury when the protein comes from urine.3. Symmetrical distal polyneuropathy is the main part of diabetic neuropathy and it was expressed as weakness of the lower limbs and pain of joints in the symptoms of Haso(下消). In Oriental medicine, acupuncture and herb medicine which effect is SopungHwalHyul can treat polyneuropathy. 4. Chief macrovascular complications are coronary artery disease and cerebrovascular disease, The cause of macrovascular complication is atherosclerosis. So the method of treating atherosclerosis should be studied in oriental medicine. 5. Diabetic foot were expressed as carbuncle and its main causes are decreasing perfusion of fool, diabetic neuropathy and infection. So these causes should be studied in oriental medicine. 6. The complications of diabetes mellitus afe very similar to the transfonnatiuns of Sogal(消渴).The control of blood glucose is indispensable to prevent and delay the complication of diabetes mellitus.

• 대한중풍순환신경학회지
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• 제10권1호
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• pp.68-73
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• 2009

Type 2 diabetes mellitus (T2DM) is a progressive disorder caused by a combination of insulin resistance and 𝛽 cell dysfunction. Sogal(消渴) is a traditional Korean medical term referring to a condition pertaining 3 major symptoms - thirst, polyphasia, polyuria. Sogal has been reported to have similar characteristics with DM. This case report demonstrates a patient with T2DM complaining of typical Sogal symptoms. We diagnosed him as So-yang person Sogal and treated him with acupuncture and herbal medicine.

• 대한한방내과학회지
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• 제38권1호
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• pp.81-91
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• 2017

Objectives: This study aimed to explore and describe how two patients diagnosed with type II diabetes mellitus were successfully cured solely through the use of herbal medicine. Methods: The patients were administered the herbal medicine to reduce symptoms of stress-induced fever with dryness. The prescribed herbal medicines included Yangkyuksanwha-tang, Hyungbangsabaek-san, Hyungbangjihwang-tang, and Hyungbangdojeock-san. Results: The therapeutic outcomes showed that all numerical levels of symptoms such as thirst, polyuria, weight loss, blood sugar, and glycated hemoglobin (HbA1c) recovered to within normal levels. Conclusions: The results of this study suggest that our medical treatment of type II diabetes mellitus diagnosed as Sogal was a valid treatment. We hope that our team's new evidence and findings will shed positive light on the treatment of type II diabetes mellitus using herbal medicine.

• 한국한의학연구원논문집
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• 제13권2호통권20호
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• pp.1-14
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• 2007

To overcome the limits of prevention and treatment against Diabetes Mellitus(DM) in Western medicine, there have been tendency finding solutions in traditional medicine based on Sogal. But Sogal had been so various concepts, classification and names. As a result there has been confusion in applying Sogal treatment to DM. So in order to clarify, it is necessary to study Sogal concepts and classification historically. The results of studying changes of Sogal concepts and classification are following : Untill AD 8 century, Sogal had not been only syndrome but also disease with throat and urinating difficulties. From 10c to 13c, Sogal had been divided three types in addition to the theories of internal organs, Samcho and complications. From 13c to 14c, the three types of Sogal theory was improved by various medical theory. But still Sogal covered the concepts of syndrome and disease. After 16c, in Chosun Dynasty. concepts of syndrome was eliminated and concepts of disease was strengthend by accounts on pathology, prognosis. complications and malignities. This tendeny was showed well in ${\ulcorner}DongEuiBoGam{\lrcorner}$ and connected to post doctors in Chosun. It was distiction with Chinese Traditional Medicine's view regarding Sogal as syndrome and disease as well, up to the present.

• Applied Biological Chemistry
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• 제45권1호
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• pp.47-52
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• 2002

동의보감의 소갈 처방에서 사용하고 있는 한약재 중에서 인슐린성 물질을 탐색하기 위해 3T3-L1 지방세포 모델을 이용하여 3T3-L1 섬유아세포의 증식 및 3T3-L1 지방세포의 분화에 미치는 영향을 살펴보았다. 3T3-L1 섬유아세포의 증식율은 반하, 후박, 대황, 오가피, 창출과 보두의 열수추출물을 첨가하였을 때 세포의 분화작용에는 영향을 미치지 않았다. 마황, 과루인, 현삼과 고삼의 추출물은 3T3-L1 섬유아세포의 분화를 촉진시켰으며, 이는 인슐린성 물질이 함유되어 있을 가능성이 높음을 시사하고 있다.