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A Study on the P~q~t Charts Applicability for Quality Improvement of Water-Sealing&Reinforcement Grouting in Tunneling Work Underneath the City (도심지 지하 터널시공 중 차수·보강 그라우팅 공사의 품질향상을 위한 P~q~t charts 적용성 연구)

  • Kim, Jin-Chun;Kim, Seok-Hyun;Yoo, Byung-Sun;Kang, Hee-Jin
    • Journal of Korean Society of Disaster and Security
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    • v.14 no.3
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    • pp.51-63
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    • 2021
  • This study is for the quality improvement of water-sealing & reinforcement grouting in tunnel of the construction of the underground transportation network underneath the city. Existing tunnel grouting process did not technically utilize P~q~t charts fully. It is due to the absence of technical methods to decide how P~q~t charts change in the presence of trouble and what the change represents in grouting. There were no standards to decide which chart pattern represents which ground characteristics, how to categorize ground types, and how to take measures according to the standards. This paper studies on the grouting type, ground characteristics, ground type categorizing method, and countermeasures for both general and algorithm-processed grouting in soil and rock layer to address the aforementioned problems. Newly improved P~q~t charts from grouting in soil was categorized into six different types. Different characteristics and categorization method was developed for each type. Countermeasures for each type of grouting process were developed so that on-site application can be readily available. Improved P~q~t charts for rock layer also have six different types of grouting. Each type was given the countermeasures for rock layer grouting process for easier applications. Therefore, it is expected to be used through out the entire process of grouting from preparation to the last report of the water-sealing & reinforcement grouting in tunnel of the construction of the underground transportation network underneath the city.

Doubly-robust Q-estimation in observational studies with high-dimensional covariates (고차원 관측자료에서의 Q-학습 모형에 대한 이중강건성 연구)

  • Lee, Hyobeen;Kim, Yeji;Cho, Hyungjun;Choi, Sangbum
    • The Korean Journal of Applied Statistics
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    • v.34 no.3
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    • pp.309-327
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    • 2021
  • Dynamic treatment regimes (DTRs) are decision-making rules designed to provide personalized treatment to individuals in multi-stage randomized trials. Unlike classical methods, in which all individuals are prescribed the same type of treatment, DTRs prescribe patient-tailored treatments which take into account individual characteristics that may change over time. The Q-learning method, one of regression-based algorithms to figure out optimal treatment rules, becomes more popular as it can be easily implemented. However, the performance of the Q-learning algorithm heavily relies on the correct specification of the Q-function for response, especially in observational studies. In this article, we examine a number of double-robust weighted least-squares estimating methods for Q-learning in high-dimensional settings, where treatment models for propensity score and penalization for sparse estimation are also investigated. We further consider flexible ensemble machine learning methods for the treatment model to achieve double-robustness, so that optimal decision rule can be correctly estimated as long as at least one of the outcome model or treatment model is correct. Extensive simulation studies show that the proposed methods work well with practical sample sizes. The practical utility of the proposed methods is proven with real data example.

A Novel Translocation Involving RUNX1 and HOXA Gene Clusters in a Case of Acute Myeloid Leukemia with t(7;21)(p15;q22)

  • Moon, Yeonsook;Horsman, Douglas E.;Humphries, R. Keith;Park, Gyeongsin
    • IMMUNE NETWORK
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    • v.13 no.5
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    • pp.222-226
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    • 2013
  • Translocations involving chromosome 21q22 are frequently observed in hematologic malignancies including acute myeloid leukemia (AML), most of which have been known to be involved in malignant transformation through transcriptional dysregulation of Runt-related transcription factor 1 (RUNX1) target genes. Nineteen RUNX1 translocational partner genes, at least, have been identified, but not Homeobox A (HOXA) genes so far. We report a novel translocation of RUNX1 into the HOXA gene cluster in a 57-year-old female AML patient who had been diagnosed with myelofibrosis 39 months ahead. G-banding showed 46,XX,t(7;21)(p15;q22). The involvement of RUNX1 and HOXA genes was confirmed by fluorescence in situ hybridization.

PARANORMAL CONTRACTIONS AND INVARIANT SUBSPACES

  • Duggal, B.P.;Kubrusly, C.S.;Levan, N.
    • Journal of the Korean Mathematical Society
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    • v.40 no.6
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    • pp.933-942
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    • 2003
  • It is shown that if a paranormal contraction T has no nontrivial invariant subspace, then it is a proper contraction. Moreover, the nonnegative operator Q = T/sup 2*/T/sup 2/ - 2T/sup */T + I also is a proper contraction. If a quasihyponormal contraction has no nontrivial invariant subspace then, in addition, its defect operator D is a proper contraction and its itself-commutator is a trace-class strict contraction. Furthermore, if one of Q or D is compact, then so is the other, and Q and D are strict ontraction.

GLOBAL WEAK SOLUTIONS FOR THE RELATIVISTIC VLASOV-KLEIN-GORDON SYSTEM IN TWO DIMENSIONS

  • Xiao, Meixia;Zhang, Xianwen
    • Bulletin of the Korean Mathematical Society
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    • v.55 no.2
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    • pp.591-598
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    • 2018
  • This paper is concerned with global existence of weak solutions to the relativistic Vlasov-Klein-Gordon system. The energy of this system is conserved, but the interaction term ${\int}_{{\mathbb{R}}^n}\;{\rho}{\varphi}dx$ in it need not be positive. So far existence of global weak solutions has been established only for small initial data [9, 14]. In two dimensions, this paper shows that the interaction term can be estimated by the kinetic energy to the power of ${\frac{4q-4}{3q-2}}$ for 1 < q < 2. As a consequence, global existence of weak solutions for general initial data is obtained.

PD Detection in Air by Capacitive Electric Field Sensor (전계센서의 원리를 이용한 공기중 부분방전신호 검출)

  • Lee, Y.H.;Lee, K.W.;Park, S.H.;Kang, S.H.;Shin, Y.S.;Lim, K.J.
    • Proceedings of the Korean Institute of Electrical and Electronic Material Engineers Conference
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    • 2002.07b
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    • pp.900-903
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    • 2002
  • Partial discharges(PD) in air, corona discharges, deteriorate the insulation strength. So, it is necessary to detect PD at an early stage before the system failure and extensive damage to the equipment. PD emit signals which can be detected by applying an capacitive electric field diagnosis. In this paper, We measured signals by capacitive electric field sensor and analyzed FFT from PD, and then compared conventional electric PD detecting method to capacitive electric field diagnosis by $\Psi-q-n$, $\Psi-v-n$, $\Psi-n$, $\Psi-q$ distributions.

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Identification Method based on q-Markov (q-Markov Cover에 기초한 동정법)

  • Bae, Jong-Il;Lee, Dong-Cheol
    • Proceedings of the KIEE Conference
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    • 2005.07d
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    • pp.2522-2524
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    • 2005
  • We need build a mathematical to apply the system theory to real system, phenomenon analysis, prediction, control, simulation and so on. Especially system identification is building a model from input and output data. This study shows q-Markov Cover based system identification. When we do this, in order to make the identification possible under more general conditions with estimation of the system order, Markov parameters and covariance parameters from input and douput data, 1 suggest the way we can get an optimal model by estimating and Identifying of covariance matrix of observation noises repeatedly.

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Studies on Analysis of Particle Lumping and Improvement of Driving Characteristics in Charged Particle Type Display (대전입자형 디스플레이에 있어서 입자뭉침의 분석 및 구동특성 개선에 관한 연구)

  • Kim, Young-Cho
    • Journal of the Korean Institute of Electrical and Electronic Material Engineers
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    • v.24 no.11
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    • pp.915-919
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    • 2011
  • We analyzed various forces affective to the charged particles in closed space, to explain the image degradation and lifetime-shortening phenomena because of particle lumping which is one of the serious problems in reflective displays. It is possible to predict the quantity of q/m which is the most important parameter in determining the optical and electrical characteristics, by calculating the image force and kinetic energy. For stable driving, the quantity of q/m must be in the defined range but it changes during the fabrication process, so we added the filtering process to solve this problem and obtained the well-defined nonlinear driving voltage coinciding with the threshold voltage. And we obtained the fully-driving property which prevents the particle lumping and decides the image quality and lifetime of panel from the optical characteristics and occupation surface of moving particles.

Metabolomics Approach for Classification of Medicinal Plants

  • Lee, Dong-Ho
    • Proceedings of the Plant Resources Society of Korea Conference
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    • 2010.05a
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    • pp.5-5
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    • 2010
  • Selection of specific medicinal sources as well as bioactive compounds is important for the preparation of medicine and related products with good quality. It is necessary to pay close attention for choosing correct medicinal sources, particularly in case of medicinal plants, because of their diversity, which can affect the quality and efficacy of medicine. Discrimination of plants based on morphological or genetic characteristics has been used as a conventional classification method of pharmaceutical sources so far; however, more need demands more general methods for accurate quality assessment of medicinal plants. In this study, ultra performance liquid chromatography/quadrupole time-of-flight mass spectrometry (UPLC/Q-TOF MS) technique applied to this metabolic profiling is a powerful tool due to its higher sensitivity, resolution, and speed compared to conventional HPLC technique. The metabolite profiling of several medicinal plants including Panax ginseng was carried out using UPLC/Q-TOF MS and total metabolites were then subsequently applied to various statistical tools to compare the patterns. The developed metabolomics tool with UPLC/Q-TOF MS successfully identified and classified the samples tested according to their origins.

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Comparison of QSAR Methods (CoMFA, CoMSIA, HQSAR) of Anticancer 1-N-Substituted Imidazoquinoline-4,9-dione Derivatives

  • Suh, Myung-Eun;Park, So-Young;Lee, Hyun-Jung
    • Bulletin of the Korean Chemical Society
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    • v.23 no.3
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    • pp.417-422
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    • 2002
  • Comparison studies of the Quantitative Structure Activity Relationship (QSAR) methods with new imidazo-quinolinedione derivatives were conducted using Comparative Molecular Field Analysis (CoMFA), Comparative Molecular Similarity Indices Analysis (CoMSIA), and the Hologram Quantitative Structure Activity Relationship (HQSAR). When the CoMFA crossvalidation value, q2, was 0.625, the Pearson correlation coefficient, r2, was 0.973. In CoMSIA, q2 was 0.52 and r2 was 0.979. In the HQSAR, q2 was 0.501 and r2 was 0.924. The best result was obtained using the CoMSIA method according to a comparison of the calculated values with the real in vitro cytotoxic activities against human ovarian cancer cell lines.