• The Journal of Korean Medicine
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• v.22 no.4
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• pp.69-78
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• 2001

Objectives : It is known that cigarette smoking is associated with increased risk of both thrombotic and hemorrhagic stroke. However, in Korea, especially in the academic world of Korean Medicine, there is a lack of study about the relation between cigarette smoking and stroke. We carried out a case-control study to clarify the relation between cigarette smoking and stroke. Method : We interviewed 441 stroke patients (236 men, 205 women) as a case group and 432 non-stroke patients (208 men, 224 women) as a control group. We investigated the smoking pattern of all patients and stroke-subtype of the case group. Smoking pattern is classed into two (Class I), four (Class II) and five groups (Class III). Class I consists of current non-smokers and current smokers. Class II consists of non-smokers, former smokers, current light smokers and current heavy smokers. Class III consists of never smoked, secondhand smokers, former smokers, Current light smokers and current heavy smokers. Stroke-subtype consists of cerebral infarction and cerebral hemorrhage. Results : The percentage of current smokers of case group is higher significantly than that of control group. The number of cigarettes smoked per day is associated positively with the risk of stroke. According to our study, generally cigarette smoking is related with ischemic stroke. The percentage of secondhand smokers of the case group is lower than that of the control group. According to our study, characteristically secondhand smoking is associated with hemorrhagic stroke. Conclusions : From the above results we found that cigarette smoking is an important risk factor of stroke - especially cerebral infarction - and the number of cigarettes smoked per day is associated positively with the risk of stroke. Characteristically according to our study, secondhand smoking is associated with hemorrhagic stroke. Overall we conclude that cigarette smoking may be an important preventable factor for stroke.

• Journal of Nutrition and Health
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• v.33 no.7
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• pp.755-762
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• 2000

female smoking especially in the population of teenage girls is regarded as an important health problem as the young female smokers are increasing sharply. We surveyed 895 teenage girls(15-19 years of age) living in a rural community in Korea for their cigarette smoking habits and the relationship between smoking status of subjects demographic variables and view on other's smoking. Of the subjects 11.6% stated that they were currently smoking and 67.3% of current smokers began smoking regularly sometimes before high school. The average smoking period of current smokers waas 20.6$\pm$1.5 mounts and they smoked 7.5 cigarettes/day on an average. Their main reason for starting to smoke was curiosity. The parents attitude for their offspring was more undemocratic in smokers. Smokers had lower academic sachievement and they had the family system such as single parent more undemocratic in smokers. Smokers had lower academic achievement and they had the family sysstem such as single parent family or divorced parent family more often than did non-smokers. Smoking status of subjects was positively related to that of their parents siblings and friends respectively. Smokers accepted others' smoking more positively than did non-smokers. Above results show that cigarette smoking is prevalent among teenage girls living in a rural community and smoking of subjects are affected by demographic variables and their view on others' smoking. Therefore the prevention the prevention programs aimed at adolescent smoking should be started before middle school and they should be included all influencing environmental factors such as family school and mass media.

• Korean Journal of Health Education and Promotion
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• v.18 no.3
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• pp.1-10
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• 2001

The purposes of this study were to identify patients' perceptions toward regulations of smoking in general hospitals and hazards caused by smoking. Moreover this study also identified smoking behaviors and punishment experience due to in-hospital smoking and education experiences of smoking in general hospitals. Around 88.0％ of all respondents regardless of either smokers or non-smokers knew that hospitals are non-smoking area. However, 71.6％ of smokers smoked during their hospital visits. For their smoking, only 51.0％ of smokers utilized smoking rooms or areas for their smoking. Only 55.1％ of smokers experienced punishments or notifications of warning due to their smoking. Around 93.0％ of inpatients and outpatients acknowledged hazards toward their health caused by smoking. However, smokers did not realize the dangerous effects of passive smoking to other persons. Only 38.1％ of smokers said that passive smoking causes hazard of others' health. 63.8％ of smokers hoped for secession of smoking but only 42.8％ of them sustained their non-smoking periods over 5 moths. Based on these results, this study insists that a more enforced smoking policy in general hospitals be desperately needed for protecting patients' health and controlling smoking at unapproved areas. Moreover hospitals should take proactive actions to prevent smoking in hospitals. A health education program in hospitals should promote patients' self-efficacy to stop smoking and patients' understanding of the hazardous effects of passive smoking in hospitals.

• Journal of Preventive Medicine and Public Health
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• v.40 no.1
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• pp.16-22
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• 2007

Objective : The purpose of this study was to evaluate the levels of DNA damage in human lymphocytes caused by smoking and other lifestyle factors. Methods : The study population consisted of 173 normal healthy male adults from 21 to 59 years old. The demographic and lifestyle variables were obtained from administered questionnaires. The level of lymphocytic DNA damage in the peripheral blood was evaluated by the Comet assay. Statistical analyses were done by general linear model analysis and Dunnett's multiple comparison. Results : The difference in DNA damage between smokers and non-smokers was statistically significant. The means for the Tail%DNA were found to be 10.48 in the current smokers and 9.60 in the non-smokers (p < 0.05). The tail moment means were 1.58 and 1.45 (p < 0.05) for the current smokers and non-smokers, respectively. The number of cigarettes smoked per day did not result in a significant difference in the level of DNA damage among the smokers. Other lifestyle factors such as age, and drinking and exercise habits were not related to DNA damage. Conclusions : The DNA damage in the lymphocytes of smokers was found to be significantly higher than that for non-smokers. However, the number of cigarettes smoked per day was not related to DNA damage. Further study is needed to evaluate the relationship between the amount of smoking and level of damage to DNA. In addition, the status of DNA repair activities should be assessed.

• Journal of the Korean Dietetic Association
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• v.4 no.2
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• pp.168-177
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• 1998

It has been reported that cigarette smoking increases free radical generation, which can also increase lipid peroxides and deplete antioxidants. The purpose of this study was to determine whether cigarette smoking and other lifestyle choices may affect serum lipid peroxide concentrations, serum antioxidant concentrations such as tocopherol and vitamin C, and serum antioxidant enzyme activity such as glutathione peroxidase and superoxide dismutase. Dietary intakes were assessed by 24-hour recall and survey questionnaires from 48 male non-smokers and 52 male smokers. Overnight fasting blood was collected and measured for individual antioxidant status. The daily vitamin C intakes of smokers tended to be lower than those of non-smokers, and the intakes of both groups were under the Recommended Daily Allowance (RDA). Vitamin E intake was sufficient for smokers and non-smokers. Serum lipid peroxide concentrations were no difference among all subjects. The serum $\alpha$-tocopherol concentrations of all subjects were in a normal range, and they were highest in mild smokers (p<0.05). Mean serum vitamin C levels were lowest in heavy smokers (p<0.05). The activities of serum glutathione peroxidase and superoxide dismutase were not significantly different in smokes and non-smokers. In conclusion, smoking did not increase oxidative stress in heathy young men. However, it is desirable for heavy smokers to consume more vitamin C than the RDA sine their serum vitamin C concentrations are relatively low.

• Journal of the Korean Dietetic Association
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• v.8 no.3
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• pp.260-268
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• 2002

The purpose of this study was to compare food behaviors, nutrient intake, clinical symptoms, and hematological findings by smoking status. Among the third grade male students from a high school in Jinchun-kun, 31 smokers and 31 nonsmokers participated in this study. A self-administered questionnaire was used to investigate food behaviors and clinical symptoms. Nutrient intake data were collected by 24-hour recall method. Blood sample was drawn from each subject to determine the levels of hemoglobin, protein, triglyceride, cholesterol, etc. The major findings were as follows; First, smokers consumed every food group except fat & oil less frequently than nonsmokers, while they consumed instant food, coffee, alcoholic beverages more frequently than nonsmokers. Dietary habits of smokers such as regularity, balanced diet, skipping meals were worse than those of non-smokers. Second, intakes of energy, fat, carbohydrate, and β-carotene of smokers were lower than those of non-smokers. Third, smokers felt fatigue and other adverse symptoms more often than non-smokers. Fourth, the levels of hemoglobin, albumin and HDL-cholesterol were significantly lower in smokers than non-smokers. Fifth, Smoking history was negatively correlated with food behaviors, energy intake and clinical symptoms. These results suggest that food behaviors, nutrient intakes, hematological findings and clinical symptoms of male high school students were affected by smoking. Therefore, in order to decrease smoking rate of the students, the effect of smoking on nutritional and health status should be informed and nutrition education should be offered to the students.

• Journal of Acupuncture Research
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• v.18 no.4
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• pp.32-45
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• 2001

Objective : This study was performed to estimate the association between cigarette smoking and effect of oriental medical treatment in low back pain. Methods : We reviewed 40 male patients of low back pain, who were hospitalized at the Oriental Medical Hospital of Se-Myung University. 40 patients were divided into 2 groups(smokers, non-smokers) and effective scores of treatments were measured on age, symptom, etc. Result & Conclusion : Between smokers and non-smokers, statistically significant differences were not found in effective scores of treatments of low back pain, but in almost every non-smokers, they were higher than those of smokers. They seems to show that possibility of the association between cigarette smoking and effect of oriental medical treatment in low back pain.

• Journal of dental hygiene science
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• v.18 no.1
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• pp.60-68
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• 2018

This study investigates the relationship between smoking and periodontal disease through quantitative analysis of intra-buccal oral pathogenic bacteria detected in smokers and aims to yield objective baseline data for applications in anti-smoking and dental health education programs. From April to May 2016, participants in an oral health management program within an intensive dental hygiene training course at Choonhae College of Health Sciences received an explanation of the study purposes and methods, after which male smokers aged 18~30 years agreed to participate voluntarily. Real-time polymerase chain reaction (PCR) analysis of oral pathogenic bacteria was performed after collecting gingival sulcus fluid samples from 67 smokers. The intra-buccal oral pathogenic bacteria distributions were analyzed based on the subjects' general characteristics, smoking behaviors, and oral care behaviors. The distribution results show that pathogens in the anterior teeth are affected (in this order) by age, toothbrush size, and smoking status; older people had fewer pathogens, those who used larger toothbrushes had more pathogens, and smokers had more pathogens, compared to non-smokers ($_{adj}R^2=19.1$). In the posterior teeth, pathogens were influenced (in this order) by smoking status, smoking duration, and the number of tooth brushings per day; smokers had more pathogens than non-smokers, and those who brushed their teeth more often had fewer pathogens ($_{adj}R^2=25.1$). The overall pathogen distribution was affected only by smoking status: smokers generally had more pathogens, compared to non-smokers. Therefore, it is necessary to provide information about the risk of periodontal disease due to smoking during anti-smoking or dental health education sessions; particularly, the use of smaller toothbrushes for anterior teeth and the need for smokers in their early twenties to quit smoking for dental health should be highly emphasized.

• Toxicological Research
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• v.30 no.2
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• pp.91-97
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• 2014

This study aimed to identify changes in the level of neuropeptides among current smokers, former smokers, and individuals who had never smoked, and how smoking habits affect obesity and metabolic syndrome (MetS). Neuropeptide levels, anthropometric parameters, and metabolic syndrome diagnostic indices were determined among male workers; 117 of these had never smoked, whereas 58 and 198 were former and current smokers, respectively. The total sample comprised 373 male workers. The results obtained from anthropometric measurements showed that current smokers attained significantly lower body weight, body mass index, waist circumference, and abdominal fat thickness values than former smokers and those who had never smoked. Current smokers' eating habits proved worse than those of non-smokers and individuals who had never smoked. The level of brain-derived neurotrophic factor (BDNF) in the neuropeptides in the case of former smokers was $23.6{\pm}9.2pg/ml$, higher than that of current smokers ($20.4{\pm}6.1$) and individuals who had never smoked ($22.4{\pm}5.8$) (F = 6.520, p = 0.002). The level of adiponectin among former smokers was somewhat lower than that of current smokers, whereas leptin levels were higher among former smokers than current smokers; these results were not statistically significant. A relationship was found between adiponectin and triglyceride among non-smokers (odds ratio = 0.660, ${\beta}$ value=-0.416, p < 0.01) and smokers (odds ratio = 0.827, ${\beta}$ value=-0.190, p < 0.05). Further, waist circumference among non-smokers (odds ratio = 1.622, ${\beta}$ value=0.483, p < 0.001) and smokers (odds ratio = 1.895, ${\beta}$ value=0.639, p < 0.001) was associated with leptin. It was concluded that cigarette smoking leads to an imbalance of energy expenditure and appetite by changing the concentration of neuropeptides such as adiponectin, BDNF, leptin, and hsCRP, and influences food intake, body weight, the body mass index, blood pressure, and abdominal fat, which are risk factors for MetS and cardiovascular disease.

• Korean Journal of Health Education and Promotion
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• v.9 no.1
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• pp.39-47
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• 1992

This study was surveyed among 1136 respondent of high school girls in seoul from Feb. 6, till Feb. 22, 1992 for the purpose of analysing the smoking of high school girls and its factor. The data was analied by X²-test and Multiple Regression and shows the following. 1. Out of 1,136 respondent, the current smokers were found to be 176, 15.5% and the former smokers were 204, 18.0%. This implies that 23.5% of high school girls seoul have experience smoking. 2. For the first smoking time in both smoking group and former smokers, it shows that the third grade of middle school lead the lists. 36.9% (65) of the smokers and 37.3(75)of former smokers experienced the first smoking at that time. 70.5%(124) of the smoking group have the intention to stop smoking and the first reason of it is health problem, 65.6%(75). 3. For the type of the school the smoking rate rages from 2.7%(7) of literary part in day time to 25.3%(97) of vocational part in evening time and the rate of smoking experience shows from 9.9%(26) literary part in day time to 25.3%(97) of vocational part in evening time. This data show that literary part in day time has the lowst rate while vocational part in eveing time the highest rate. 4. Compared with non smoker group, smoking group and former smoking group spent more money (P<0.001) and felt dissatisfied with school life and didn't have good school records. 5. Smoking group and former smokers have more boy friends than non smoking group and in most cases their boy friend have smoking habits (P<0.001) and it is the same with their gril friend (P<0.001). 6. Compared with non smoker group, smoking group and former smokers lack of their parents' interest (P<0.001). But whether it is strict or free there is little difference among the three group. 7. For smoking group and former smoking group, in most cases their parent, brother and sister tend to smoke and especially their sisters' smoking has much influence on their smoking in comparison with non-smokers. 8. Compared with non-smoker group, smoking group and former smoking group tend to think less of the harm of smoking. In regard with health problem, more smoking group and former smokers think that smoking can relieve the stress (P<0.001), and more non-smokers know that when a pregnant woman smokes, it can cause the lack of supply of Oxygen{P<0.01). 9. Smoking group and former smoking group have more positive attitude towards smoking than non-smokers and tend to agree to their boy and girl friends' smoking(P<0.001).