• Bulletin of the Korean Chemical Society
• /
• v.34 no.9
• /
• pp.2629-2634
• /
• 2013

Fisetin is a naturally occurring flavonoid with some anti-cancer and anti-inflammation capabilities. In this study, we perform docking studies between human c-Jun N-terminal kinase 1 (JNK 1) and fisetin and proposed a binding model of fisetin and JNK 1, in which the hydroxyl groups of the B ring and oxygen at the 4-position of the C ring play key roles in binding interactions with JNK. Fluorescence quenching and saturation-transfer difference (STD) NMR experiments showed that fisetin exhibits good binding affinity to JNK, $1.32{\times}10^8M^{-1}$. The anti-inflammatory activity of fisetin was also investigated. Fisetin significantly suppressed tumor necrosis factor, the NO production, and macrophage inflammatory cytokine release in LPS-stimulated RAW264.7 mouse macrophages. We found that the anti-inflammatory cascade of fisetin was mediated through the JNK, and cyclooxygenase (COX)-2 pathways. Our findings suggest the potential of fisetin as an anti-inflammatory agent.

• Proceedings of the Korean Society of Crop Science Conference
• /
• 2022.10a
• /
• pp.189-189
• /
• 2022

Soil salinity negatively affects plant growth, productivity, and metabolism. Rice is known to have more sensitive phenotypes than other cereal crops, such as wheat, sorghum, and barley. We characterized the molecular function of rice C3HC4 as a really interesting new gene (RING). Oryza sativa RING finger protein H2-3 (OsRFPH2-3) was highly expressed in 100 mM NaCl. To identify the localization of OsRFPH2-3, we fused vectors that include C-terminal GFP protein (35S;;OsRFPH2-3-GFP). OsRFPH2-3 was expressed in the nucleus in rice protoplasts. An in vitro ubiquitin assay demonstrated that OsRFPH2-3 possessed E3-ubiquitin ligase activity. However, the mutated OsRFPH2-3 were not possessed any E3-ubiquitin ligase activity. Under normal conditions, there is no significant phenotypic difference between transgenic plants and WT plants. However, OsRFPH2-3-overexpressing plants exhibited higher fresh weight and length under saline conditions. Also, transgenic plants maintain higher chlorophyll, proline, and soluble sugar contents and lower H₂O₂ and MDA contents than the wild type; these results support transgenic plants with enhanced salinity tolerance phenotypes.

• Proceedings of the Korean Society of Crop Science Conference
• /
• 2023.04a
• /
• pp.156-156
• /
• 2023

Salinity is a major abiotic stress that limits rice productivity in many regions of the world. In order to develop salt stress tolerant rice plants, genetic engineering is a promising approach. We characterized the molecular function of rice C3H2C3 as a really interesting new gene (RING). Oryza sativa RING finger protein H2-3 (OsRFPH2-3) was highly expressed in 100 mM NaCl. To identify the localization of OsRFPH2-3, we fused vectors that include C-terminal GFP protein (35S;;OsRFPH2-3-GFP). OsRFPH2-3 was expressed in the nucleus in rice protoplasts. An in vitro ubiquitin assay demonstrated that OsRFPH2-3 possessed E3-ubiquitin ligase activity. However, the mutated OsRFPH2-3 were not possessed any E3-ubiquitin ligase activity. Under salinity conditions, OsRFPH2-3-overexpressing plants exhibited higher chlorophyll, proline, SOD, POD, CAT, and soluble sugar contents and lower H₂O₂ accumulation than wild-type plants, supporting transgenic plants with enhanced salinity tolerance phenotypes. OsRFPH2-3-overexpressing plants exhibited low Na+ accumulation and Na+/K+ ratios in their roots. Theses results suggest that overexpression of OsRFPH2-3 can make plant insensitivity about salinity conditions.

• KSII Transactions on Internet and Information Systems (TIIS)
• /
• v.9 no.5
• /
• pp.1870-1880
• /
• 2015

In this paper, we studied facial impression construction with smartphones in a series of experiments with two smartphone applications: SmartRing and SystemSens+. In the first experiment, impressions of faces associated with different music genres (trot vs. classical) were compared to impressions formed from a facial image alone along the social warmth and intelligence dimensions. In the second experiment, the effect of similarity attraction was investigated by manipulating the extroversion of facial images. Results indicated that impressions of faces cannot only be constructed along the social warmth and intelligence dimensions, but can also be made more or less attractive based on their similarity to the viewer's personality. Our experiments provide interesting insights into facial impressions formed in a smartphone environment.

• Journal of the Korea Society of Computer and Information
• /
• v.22 no.10
• /
• pp.55-62
• /
• 2017

In this paper, we proposes a multi-ring based mobile sink location scheme for solar-powered wireless sensor network (WSN). The proposed scheme maintains the multi-rings in which nodes keep the current location of sink node. With the help of nodes in multi-rings, each node can locate the sink node efficiently with low-overhead. Moreover, because our scheme utilizes only surplus energy of a node, it can maintain multiple rings without degrading any performance of each node. Experimental results show that the proposed scheme shows much better latency and scalability with lower energy-consumption than the existing single-ring based scheme.

• IEIE Transactions on Smart Processing and Computing
• /
• v.2 no.2
• /
• pp.57-66
• /
• 2013

Wireless Sensor Networks consist of small, inexpensive, low-powered sensor nodes that communicate with each other. To achieve a low communication cost in a resource constrained network, a novel concept of signcryption has been applied for secure communication. Signcryption enables a user to perform a digital signature for providing authenticity and public key encryption for providing message confidentiality simultaneously in a single logical step with a lower cost than that of the sign-then-encrypt approach. Ring signcryption maintains the signer's privacy, which is lacking in normal signcryption schemes. Signcryption can provide confidentiality and authenticity without revealing the user's identity of the ring. This paper presents the security notions and an evaluation of an ID-based ring signcryption scheme for wireless sensor networks. The scheme has been proven to be better than the existing schemes. The proposed scheme was found to be secure against adaptive chosen ciphertext ring attacks (IND-IDRSC-CCA2) and secure against an existential forgery for adaptive chosen message attacks (EF-IDRSC-ACMA). The proposed scheme was found to be more efficient than scheme for Wireless Sensor Networks reported by Qi. et al. based on the running time and energy consumption.

• Journal of Communications and Networks
• /
• v.14 no.6
• /
• pp.653-661
• /
• 2012

High-availability seamless redundancy (HSR) is a redundancy protocol for Ethernet networks that provides two frame copies for each frame sent. Each copy will pass through separate physical paths, pursuing zero fault recovery time. This means that even in the case of a node or a link failure, there is no stoppage of network operations whatsoever. HSR is a potential candidate for the communications of a smart grid, but its main drawback is the unnecessary traffic created due to the duplicated copies of each sent frame, which are generated and circulated inside the network. This downside will degrade network performance and might cause network congestion or even stoppage. In this paper, we present two approaches to solve the above-mentioned problem. The first approach is called quick removing (QR), and is suited to ring or connected ring topologies. The idea is to remove the duplicated frame copies from the network when all the nodes have received one copy of the sent frame and begin to receive the second copy. Therefore, the forwarding of those frame copies until they reach the source node, as occurs in standard HSR, is not needed in QR. Our example shows a traffic reduction of 37.5%compared to the standard HSR protocol. The second approach is called the virtual ring (VRing), which divides any closed-loop HSR network into several VRings. Each VRing will circulate the traffic of a corresponding group of nodes within it. Therefore, the traffic in that group will not affect any of the other network links or nodes, which results in an enhancement of traffic performance. For our sample network, the VRing approach shows a network traffic reduction in the range of 67.7 to 48.4%in a healthy network case and 89.7 to 44.8%in a faulty network case, compared to standard HSR.

• Proceedings of the Korean Institute of Navigation and Port Research Conference
• /
• 2002.11a
• /
• pp.13-19
• /
• 2002

Design and implementation methodologies on the performance evaluation system of two-channel ring-core Flux-Gate Compass (FG-Compass) are described, with evaluation procedures and methods based on the polynomial regression models. Performance evaluation system is consists of a step motor driving unit, a bearing transmitting unit and, evaluation programs using polynomial regression formulae. Through performance evaluation tests, total residual deviation tests, total residual deviation of $\pm$4$^{\circ}$ and eigen residual deviation of $\pm$2$^{\circ}$ are obtained from the FG-Compass. The result is more accurate values than the typical FG-Compass with eigen residual deviation of $\pm$4$^{\circ}$ and is provide a possibility to develop a high performance FG-Compass. In addition, the design methodology of a smart FG-Compass with the self estimation and correction of residual deviations is also discussed.

• IEIE Transactions on Smart Processing and Computing
• /
• v.4 no.6
• /
• pp.384-390
• /
• 2015

There are two main artifacts in reconstructed images from in-beam positron emission tomography (PET). Unlike generic PET, in-beam PET uses the annihilation photons that occur during heavy ion therapy. Therefore, the geometry of in-beam PET is not a full ring, but a partial ring that has one or two openings around the rings in order for the hadrons to arrive at the tumor without prevention of detector blocks. This causes truncation in the projection data due to an absence of detector modules in the openings. The other is a ring artifact caused by the gaps between detector modules also found in generic PET. To sum up, in-beam PET has two kinds of gap: openings for hadrons, and gaps between the modules. We acquired three types of simulation results from a PET system: full-ring, C-ring and dual head. In this study, we aim to compensate for the artifacts that come from the two types of gap. In the case of truncation, we propose a method that uses prior knowledge of the location where annihilations occur, and we applied the discrete-cosine transform (DCT) gap-filling method proposed by Tuna et al. for inter-detector gap.

• Proceedings of the Korean Institute of Information and Commucation Sciences Conference
• /
• 2018.10a
• /
• pp.526-528
• /
• 2018

This paper proposes a small, flexible dipole antenna for wireless power transmission of smart devices in a Wi-Fi environment. The proposed antenna is a mini-dipolar antenna structure with a split ring resonator in the center and is a small dipole antenna with a size of 32mm. The split ring resonator dipole antenna showed a reduction of about 20% compared to the same size of the dipole antenna.