• Radiation Oncology Journal
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• v.27 no.3
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• pp.120-125
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• 2009

Purpose: We wanted to present the preliminary results of intensity-modulated radiotherapy (IMRT) for the treatment of tonsillar cancer. Materials and Methods: We retrospectively analyzed 12 patients who underwent IMRT for tonsillar cancer at Asan Medical Center between November 2002 and February 2007. Seven patients (58%) received definitive treatment, and five (42%) were treated in the postoperative setting. Among the definitively treated patients, 6 patients received cisplatin-based chemotherapy regimens. Simultaneous modulated accelerated radiation therapy (SMART) was used in nine patients. The prescribed dose was 72 Gy at 2.4 Gy/fraction for the definitively treated cases and 61.6 Gy at 2.2 Gy/fraction for the postoperative cases. The median follow-up period was 34 months. Results: All twelve patients completed treatment without interruption, and eleven showed a complete response. One patient had persistent loco-regional disease after treatment. The three-year estimates of loco-regional control, disease-free survival and overall survival were 91.7%, 91.7%, and 100%. The worst acute mucositis was Grade 1 in four patients, Grade 2 in five patients, Grade 3 in two patients and Grade 4 in one patient. Grade 3 xerostomia was observed in six patients. Conclusion: Intensity-modulated radiotherapy was shown to be a safe and effective treatment modality for tonsillar cancer. Further studies with a larger number of patients and a longer follow-up period are needed to evaluate the ultimate tumor control and late toxicity of IMRT for treating tonsillar cancer.

• IEIE Transactions on Smart Processing and Computing
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• v.3 no.1
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• pp.28-34
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• 2014

Recently, ultrasound therapy has become a new and effective treatment for many brain diseases. Therefore, skull-mimicking phantoms have been developed to simulate the skull and brain tissue of a human and allow further research into ultrasound therapy. In this study, the suitability of various skull-mimicking materials(HDPE, POM C, Acrylic) for studies of brain-tumor treatments was evaluated using focused ultrasound. The acoustic properties of three synthetic resins were measured. The skull-mimicking materials were then combined with an egg white phantom to observe the differences in the ultrasound beam distortion according to the type of material. High-intensity polyethylene was found to be suitable as a skull-mimicking phantom because it had acoustic properties and a denatured-area shape that was close to those of the skull,. In this study, a skull-mimicking phantom with a multi-layer structure was produced after evaluating several skull-mimicking materials. This made it possible to predict the denaturation in a skull in relation to focused ultrasound. The development of a therapeutic protocol for a range of brain diseases will be useful in the future.

• Progress in Medical Physics
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• v.24 no.4
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• pp.230-236
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• 2013

Our purpose is to present a novel technique for delivering craniospinal irradiation in the supine position using a perfect match, field-in-field (FIF) intrafractional feathering, and simple forward-optimization technique. To achieve this purpose, computed tomography simulation was performed with patients in the supine position. Half-beam, blocked, opposed, lateral, cranial fields with a collimator rotation were matched to the divergence of the superior border of an upper-spinal field. Fixed field parameters were used, and the isocenter of the upper-spinal field was placed at the same source-to-axis distance (SAD), 20 cm inferior to the cranial isocenter. For a lower-spinal field, the isocenter was placed 40 cm inferior to the cranial isocenter at a constant SAD. Both gantry and couch rotations for the lower-spinal field were used to achieve perfect divergence match with the inferior border of the upper-spinal field. A FIF technique was used to feather the craniospinal and spinal-spinal junction daily by varying the match line over 2 cm. The dose throughout the target volume was modulated using the FIF simple forward optimization technique to obtain homogenous coverage. Daily, image-guided therapy was used to assure and verify the setup. This supine-position, perfect match craniospinal irradiation technique with FIF intrafractional feathering and dose modulation provides a simple and safe way to deliver treatment while minimizing dose inhomogeneity.

• The Journal of the Korea Contents Association
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• v.19 no.4
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• pp.41-53
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• 2019

As the paradigm of healthcare shifts from the center of treatment to the center of prevention, products and services related to disease prevention are emerging at domestic and abroad. The government considers the smart healthcare industry as a solution to healthcare problems such as an increase in the number of chronic illnesses and an increase in the burden of medical expenses. The purpose of this study is to explore the factors affecting the use of smart healthcare products and services focusing on Health Literacy and health related personal characteristics and to provide policy implications. The subjects of the questionnaire are 1,027 adults over 20 in the nation, and conducted an online survey. In addition, the factors were analyzed by decision tree method. As a result, most of the respondents(76.9%) did not have experience using Smart Healthcare products and services. However, in the Health Literacy question, there was a difference in use experience depending on the degree of difficulty in using the mass media information. Other factors were the degree of intention to use new technology, the understanding of counseling about family members and friends, and health checkups. In order to enable self-healthcare through smart healthcare products and services, the ability of consumers to explore and utilize health information from the mass media should be improved. In addition, government and enterprise efforts are needed to achieve this.

• Smart Structures and Systems
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• v.13 no.1
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• pp.25-39
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• 2014

The axisymmetric dynamic instability of polar orthotropic sandwich annular plate combined with electrorheological (ER) fluid core layer and constraining layer are studied in this paper. And, the ER core layer and constraining layer are used to improve the stability of the annular plate system. The boundaries of instability regions for the polar orthotropic sandwich annular plate system are obtained by discrete layer annular finite element and the harmonic balance method. The rheological property of an electrorheological material, such as viscosity, plasticity, and elasticity can be controlled by applying different electric field strength. Thus, the damping characteristics of the sandwich system are more effective when the electric field is applied on the sandwich structure. Additionally, variations of the instability regions for the polar orthotropic sandwich annular plate with different applying electric field strength, thickness of ER layer and some designed parameters are investigated and discussed in this study.

• IEIE Transactions on Smart Processing and Computing
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• v.5 no.6
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• pp.395-402
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• 2016

In these days, the wearable devices have been developed for measuring biological data effectively. However, wearable devices have tissue allege and noise problem. Also, it is impossible for a remote center to identify the person whose data are measured by wearable devices, which could trigger a communication problem over treatment. To solve these problems, biometric measurement based on a non-contact method, such as face image sequencing is necessary. This makes it possible to measure biometric data without any operation and side effects. This system can monitor the biological signals of people in real time without allege and noise and simultaneously identify them. In this paper, we propose an authentication process while measuring biometric data, through a non-contact method.

• Proceedings of the Korea Information Processing Society Conference
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• 2015.04a
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• pp.90-92
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• 2015

최근 IT기술의 발달과 의료 서비스의 증가로 웨어러블 헬스케어에 대한 관심이 높아지고 있다. 기존 원칙 진료 시스템에서는 의사와 환자의 직접적인 대면 없이 진료데이터만으로 환자를 판단함으로 인하여 의료서비스의 질이 저하되는 문제가 있었다. 또한 원격진료만으로는 사용자의 증상을 정확하게 전달 할 수 가 없기 때문에 원격진료에 대한 사용자의 만족도가 낮았다. 이를 위해 본 논문에서는 VoIP 환경에서 화상진료를 지원하는 SIP 기반 스마트폰 헬스케어 시스템을 제안한다.

• International journal of advanced smart convergence
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• v.12 no.3
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• pp.89-103
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• 2023

Obstructive sleep apnea (OSA) is one of the most prevalent sleep disorders that can lead to serious consequences, including hypertension and/or cardiovascular diseases, if not treated promptly. Continuous positive airway pressure (CPAP) is widely recognized as the most effective treatment for OSA, which needs the proper titration of airway pressure to achieve the most effective treatment results. However, the process of CPAP titration can be time-consuming and cumbersome. There is a growing importance in predicting personalized CPAP pressure before CPAP treatment. The primary objective of this study was to optimize the CPAP titration process for obstructive sleep apnea patients through EEG feature engineering with machine learning techniques. We aimed to identify and utilize the most critical EEG features to forecast key OSA predictive indicators, ultimately facilitating more precise and personalized CPAP treatment strategies. Here, we analyzed 126 OSA patients' PSG datasets before and after the CPAP treatment. We extracted 29 EEG features to predict the features that have high importance on the OSA prediction index which are AHI and SpO2 by applying the Shapley Additive exPlanation (SHAP) method. Through extracted EEG features, we confirmed the six EEG features that had high importance in predicting AHI and SpO2 using XGBoost, Support Vector Machine regression, and Random Forest Regression. By utilizing the predictive capabilities of EEG-derived features for AHI and SpO2, we can better understand and evaluate the condition of patients undergoing CPAP treatment. The ability to predict these key indicators accurately provides more immediate insight into the patient's sleep quality and potential disturbances. This not only ensures the efficiency of the diagnostic process but also provides more tailored and effective treatment approach. Consequently, the integration of EEG analysis into the sleep study protocol has the potential to revolutionize sleep diagnostics, offering a time-saving, and ultimately more effective evaluation for patients with sleep-related disorders.

• Journal of the Institute of Electronics Engineers of Korea CI
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• v.46 no.2
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• pp.27-35
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• 2009

A paradigm of medical industry is changing quickly to u-healthcare according to entry toward an aging society and improvement of quality of life(QoL). The change toward u-healthcare is meaningful since meaning of healthcare is redefined by prevention and management instead of medical service such as diagnosis of disease and treatment. However, the interest about u-healthcare is only concentrated to derivation of new healthcare service, development of medical measurement appliances(Sensors), and integration and standardization of medical information. Therefore, in this paper, the main ai of this study is trying to realize and implement u-healthcare technology through primary philosophies of ubiquitous composition such as Disappear Computing, Invisible Computing, and Calm Computing and development of user-centered technology.

• Journal of Internet Computing and Services
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• v.17 no.2
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• pp.59-65
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• 2016

The result of analyzing the cognitive reaction due to the color environment has been applied to various filed especially in medical field. Moreover, the study about the identification of patient's condition and examination the brain activity by collecting the bio-signal based on the color environment is being actively conducted. Even though, there were a variety of experiments by convention the color environment using a light or LED color, it still has a problem that affects the psychological information. Therefore, our proposed system using a HMD (Head Mounting display) to provide a completed color environment condition. This system uses the BMS(Biomedical System) to collect the biometric information which responds to the specific color condition and the human body response information can be measured by the development the Memory and Attention test on Mobile phone. The collection of Biometric information includes electro cardiogram(ECG), respiration, oxygen saturation (Sp02), Bio-impedance, blood pressure will store in the database. In addition, we can verify the result of the human body reaction in the color environment by Memory and Attention application. By utilizing the reaction of the human body information that is collected thought the proposed system, we can analyze the correlation between the physiological information and the color environment. And we also expect that this system can apply to the medical diagnosis and treatment. For future work, we will expand the system for prediction and treatment of Alzheimer disease by analyzing the visualization data through the proposed system. We will also do evaluation on the effectiveness of the system for using in the rehabilitation program.