• Management & Information Systems Review
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• v.15
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• pp.109-145
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• 2004

Upcoming 21st century, Management circumstance for a small and medium enterprise have been rapidly changed by Knowledge management, Informationization, Hi-technology. Changing from an era of small concept to strong concept, It will be a severe innovation period and can not survive with life as the same as the past, It is the era of best which mean only the best can survive, None of the average faculty can survive. Due to rapid proceeding of innovation of Informationization, It stimulate acceleration of technology innovation, infinity competition regardless the nation boarder, result in proceeding to Informationization. A small and medium enterprise is defined as smaller size of business than big business as point of capital, employee, output. It is concept, which usually used against concept of big business. When define a small and medium enterprise, criteria to determine a small and medium enterprise is depends on country and a category of business. However, In every country, A small and medium enterprise is getting be bigger and importance factor in whole industry. A small and medium enterprise is well developed and also well balanced with a large enterprise in the developed country. All around in the world, Interest about a small and medium enterprise is becoming higher. It is actively researching into a small and medium enterprise as the mean to create new employment, new industry, as means to from integration of a all and medium enterprise,as source of high competitive power. The status quo of rapid changing into informationization have been realized at considerable level in Korea. Information society is defined as information technology is main key to determine individuals competitiveness, which can solve effectively the side effect result from industrialization. It cleary imply that information technology is the most promising and important industry in 21st century. Therefore, We should seek to foster independent a small and medium enterprise and develop them corresponding to new concept of a small and medium enterprise in 21st century. The main frame of policy should be new economic system, which can contribute establishment of a small and medium enterprise, management innovation. It also attribute a small and medium enterprise to reveal their creative. New economic paradigm in 21st will be expanded with organization, market, technology. So far, a small and medium enterprise has been acknowledge as economic weaker and the one should be protected. However, In 21st century a small and medium enterprise will be considered as active majority or a source of creative. Development of technology to produce a small quantity with variety product and acceleration of knowledge and informationization will result in comparative merits of a small and medium enterprise. Hereby, The role and relative importance of a small and medium enterprise in our economic will getting be larger and It will be developed as the main force to activate the economic. However, Only a small and medium enterprise, which overcome difficulty with active desire and effort to improve their lot can be developed as a competitive enterprise in 21st century in considering themselves to be developed as diversity, active, independent, business by an enterprise.

• Genomics & Informatics
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• v.7 no.3
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• pp.175-177
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• 2009

We have developed WinBioDBs with Windows interfaces, which include importing modules and searching interfaces for 10 major public databases such as GenBank, PIR, SwissProt, Pathway, EPD, ENZYME, REBASE, Prosite, Blocks, and Pfam. User databases can be constructed with searching results of queries and their entries can be edited. The program is a stand-alone database searching program on Windows PC. Database update features are supported by importing raw database files and indexing after downloading them. Users can adjust their own searching environments and report format and construct their own projects consisting of a combination of a local databases. WinBioDBs are implemented with VC++ and its database is based on MySQL.

• Journal of Korean Society of Industrial and Systems Engineering
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• v.19 no.40
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• pp.351-360
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• 1996

Korean construction companies are now in very difficult situation due to the recent construction accident, opening of domestic market, the advent of boundless competition period in WTO, etc .Introduction of quality management system is quite urgent in order to strengthen our international competitiveness through the superiority of quality and foster the long term growth of organization. Substantially, many companies are proceeding with or completed the introduction of quality management system but small and medium sized construction companies have difficulties due to lack of money and man power. In this paper, five stage procedures, which can be efficiently applied to introduction and operation of qualify management system, have been suggested to help the minor construction companies which want to adopt the quality management system. This study is considered to be helpful for the companies which will introduce quality management system.

• Proceedings of the Korean Society of Applied Pharmacology
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• 1994.04a
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• pp.82-87
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• 1994

Signal transduction through G protein-coupled receptors comprises three functional components, a receptor, a G protcin and a effector protein. Work over the last sevcral ycars has led to the characterization or virtually all of the components or these systems. what has come out or those studies is that these mechanisms of signal transduction are pervasive in nature being found in mammalian and avian species, as well as lower organisms such as yeast and slime mold. It is known that G protein-coupled receptors mediate the action of such diverse molecules such as small hormones and neurotransmitters, small peptide molecules as well as glycoprotein hormones and various sensory perceptions such as light, olfaction and most likely taste.

• Journal of the Korean Institute of Rural Architecture
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• v.15 no.2
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• pp.33-40
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• 2013

The purpose of this study is to clarify the actual condition of the plan of high schools in the rural area. Recently, many high schools are remodeling the buildings and facilities based on the departmentalized classroom system. This study, through analyzing on 2 remodeling cases of small high schools in the rural area of gyeongnam. This article discuses about the basic characteristics of the plan composition and the education programs of 2 small high schools. This study is showing the variation before and after remodeling and space organization types. The results of this study are summarized as follows; 1) Most of them take horizontal zoning system in the department classrooms. 2) Number and area of teachers' laboratory ware increased in most of floors. 3) Sample schools took much more spaces of homebase than before. 4) Consideration is given to the main subject spaces before the other subject spaces.

• The Journal of Small Business Innovation
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• v.20 no.4
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• pp.33-38
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• 2018

Kyocera Corporation is an electronic device, information equipment, and telecommunications equipment manufacturing company headquartered in Kyoto, Japan. The company's success has depended on its differentiated technology in ceramic manufacturing at the first stage. This technology was first sold to produce a part in TV CRT monitors, which boomed in the 1960s right after the company's launch. Since its founding in 1959, the company has been continuously exploring technological, product, and business development backed by its strong entrepreneurial mindset. This mindset is nurtured by the "Kyocera philosophy," the most important vision and motto of the company, which educates and encourages employees to grow themselves, respect others, and behave for all. This philosophy was advocated by the founder, Kazuo Inamori.

• Genomics & Informatics
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• v.1 no.1
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• pp.55-60
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• 2003

The nucleotide sequence of pZMO1, a small cryptic plasmid of Zymomonas mobilis ATCC10988 was determined. Analysis of 1,680 bp of sequence revealed $69\%$ identity with Shigella sonnei plasmid, pKYM and $61\%$ identity with Nostoc sp. ss DNA replicating plasmid. Analysis of a deduced amino acid sequence of an orf of pZMO1 revealed $75\%$ identity and $90\%$ similarity with the repA gene of Synechocystis sp. plasmid pCA2.4. The upstream region of the repA gene of pZMO1 possesses six directed repeat sequences and two inverted repeat sequences at downstream of the IR consensus sequence of nick region of rolling circle replication (RCR) plasmid. A typical terminator hairpin structure was found at the downstream region of repA gene. Degradation of single-stranded plasmid DNA by S1 nuclease was detected by Southern hybridization. It suggests that pZMO1 replicates by a rolling circle mechanism in Z. mobilis ATCC10988 cells.

• Genomics & Informatics
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• v.1 no.1
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• pp.20-24
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• 2003

The analysis of DNA microarry data is one of the most important things for functional genomics research. The matrix representation of microarray data and its successive 'optimal' incisional hyperplanes is a useful platform for developing optimization algorithms to determine the optimal partitioning of pairwise proximity matrix representing completely connected and weighted graph. We developed Deterministic Annealing (DA) approach to determine the successive optimal binary partitioning. DA algorithm demonstrated good performance with the ability to find the 'globally optimal' binary partitions. In addition, the objects that have not been clustered at small non­zero temperature, are considered to be very sensitive to even small randomness, and can be used to estimate the reliability of the clustering.

• Genomics & Informatics
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• v.5 no.1
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• pp.30-31
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• 2007

Many visualization tools have been designed to aid information processing during whole genome projects. We have developed a trace viewer program, ChroView, which can read a chromatogram file and display the chromatogram traces of the four bases. The program can be used to examine sequencing quality and base-calling errors. It can also help researchers to edit and save base-calling results while browsing the traces. Additionally, this program has a basecalling feature which can produce supplementary data for validation of the results from other base-calling programs.

• Genomics & Informatics
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• v.6 no.2
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• pp.95-97
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• 2008

Many bioinformatics sites have managed local bio-databases, including major databases such as GenBank and PIR with update load. We have developed several programs to monitor the update status of these databases and to FTP them automatically. These programs can be used for maintaining local bio-databases as recent versions and providing up-to-date databases through FTP sites. Currently, the program serves major bio-databases and will extend to accommodate many more bio-databases.