• 한국인터넷방송통신학회논문지
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• 제19권6호
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• pp.79-85
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• 2019

최근 소형 레이더는 한번의 타격으로 표적의 시스템을 무능화시키기 위해 높은 거리해상도를 갖는 소형 밀리미터파 레이더 개발을 요구한다. 높은 거리해상도를 갖는 소형 밀리미터파 레이더가 표적을 획득하고, 추적하기 위해서는 대용량의 데이터를 실시간으로 처리해야한다. 본 논문에서는 소형 밀리미터파 레이더에서 요구하는 대용량의 데이터를 실시간으로 처리하기 위한 실시간 데이터 전처리 방법을 정리하였다. 또한 실시간 데이터 전처리 방법으로 제시한 디지털 IF(Intermediate Frequency) 수신기, Window처리, DFT(Discrete Fourier Transform)를 FPGA (Field Programmable Gate Array)를 활용하여 구현하였다. 마지막으로 구현한 실시간 데이터 전처리 모듈은 소형 밀리미터파 레이더를 위한 신호처리기에 적용하여 실시간 데이터 전처리 기능과 관련된 성능시험으로 검증하였다.

• Asian Pacific Journal of Cancer Prevention
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• 제14권9호
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• pp.5281-5286
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• 2013

Purpose: Prostate cancer caused by the abnormal disorderly growth of prostatic acinar cells is the most prevalent cancer of men in western countries. We aimed to screen out differentially expressed genes (DEGs) and explore small molecule drugs for prostate cancer. Materials and Methods: The GSE3824 gene expression profile of prostate cancer was downloaded from Gene Expression Omnibus database which including 21 normal samples and 18 prostate cancer cells. The DEGs were identified by Limma package in R language and gene ontology and pathway enrichment analyses were performed. In addition, potential regulatory microRNAs and the target sites of the transcription factors were screened out based on the molecular signature database. In addition, the DEGs were mapped to the connectivity map database to identify potential small molecule drugs. Results: A total of 6,588 genes were filtered as DEGs between normal and prostate cancer samples. Examples such as ITGB6, ITGB3, ITGAV and ITGA2 may induce prostate cancer through actions on the focal adhesion pathway. Furthermore, the transcription factor, SP1, and its target genes ARHGAP26 and USF1 were identified. The most significant microRNA, MIR-506, was screened and found to regulate genes including ITGB1 and ITGB3. Additionally, small molecules MS-275, 8-azaguanine and pyrvinium were discovered to have the potential to repair the disordered metabolic pathways, abd furthermore to remedy prostate cancer. Conclusions: The results of our analysis bear on the mechanism of prostate cancer and allow screening for small molecular drugs for this cancer. The findings have the potential for future use in the clinic for treatment of prostate cancer.

• 환경영향평가
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• 제17권1호
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• pp.47-56
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• 2008

Total Maximum Daily Load(TMDL) is a core basin management system to assign total emissions of pollutants to unit basin and emission source within a limit of the target water quality and to secure sustainability. considering "Environment and development" together. By current technical guidance of TMDL, the water quality in the riverbed of which the target water quality is noticed, must achieve the target; and the water quality standard for evaluating achievement of the target should be prescribed as non-excessive probability quality of water on the basis of the pertinent water quality documents. Therefore, the study calculated the target water quality by each unit basin which the target water quality must be noticed through the analysis of probability for water quality documents in rivers at the time of establishing a plan, and the study evaluated the achievement possibility of the target water quality by analyzing and comparing the target water quality plan with the standard water quality to evaluate the achievement of the target water quality. As the result, applying the proposed method to Mihocheon River system, it is concluded that selected the target water quality (Each BOD 3.3mg/1 and BOD 3.0mg/1) in Miho A and Musim A is available. Of course, it showed that the target water quality: BOD 2.5mg/1 in Miho A and BOD 3.0mg/1 in Musim A, could be achieved if the small reduction in B unit area was implemented.

• Bulletin of the Korean Chemical Society
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• 제27권5호
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• pp.657-662
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• 2006

Identification of accessible sites in targeted RNAs is a major limitation to the effectiveness of antisense oligonucleotides. A class of antisense oligodeoxynucleotides, known as the “10-23” DNA enzyme or DNAzyme, which is a small catalytic DNA, has been shown to efficiently cleave target RNA at purine-pyrimidine junctions in vitro. We have designed a strategy to identify accessible cleavage sites in the target RNA, which is hepatitis C virus nonstructural gene 3 (HCV NS3) RNA that encodes viral helicase and protease, from a pool of random DNAzyme library. A pool of DNAzymes of 58 nucleotides-length that possess randomized annealing arms, catalytic core sequence, and fixed 5'/3'-end flanking sequences was designed and screened for their ability to cleave the target RNA. The screening procedure, which includes binding of DNAzyme pool to the target RNA under inactive condition, selection and amplification of active DNAzymes, incubation of the selected DNAzymes with the target RNA, and target site identification on sequencing gels, identified 16 potential cleavage sites in the target RNA. Corresponding DNAzymes were constructed for the selected target sites and were tested for RNA-cleavage in terms of kinetics and accessibility. These selected DNAzymes were effective in cleaving the target RNA in the presence of $Mg^{2+}$. This strategy can be applicable to identify accessible sites in any target RNA for antisense oligonucleotides-based gene inactivation methods.

• 한국인터넷방송통신학회논문지
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• 제18권3호
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• pp.61-69
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• 2018

본 논문에서는 밀리미터파대역의 공대지 레이다에서 이중 편파 채널을 활용한 지상 표적을 식별하기 위한 방법을 제안한다. 먼저 공대지 레이다의 조우 상황에서 Push-Broom 표적 탐지 방법을 설명하고 수신 신호를 모델링한다. 시간 영역 스펙트럼 추정 기법인 RELAX 알고리즘을 이용하여 산란점을 추출하고 표적의 특성 벡터를 생성하였다. 그리고 이를 기반으로 각각의 4표적에 대한 DB를 구성하였다. 제안하는 방법으로 표적 식별 시뮬레이션을 수행한 결과 이중 편파 채널의 데이터를 이용하면 단일 채널에 비해서 표적 식별률이 최대 15% 이상 높아지는 것을 확인할 수 있었다.

• 한국컴퓨터정보학회논문지
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• 제9권1호
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• pp.63-70
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• 2004

본 논문에서는 자체적으로 개발된 항공기의 적외선 열상표적 시스템의 모델링, 설계, 성능시험 결과 등에 대하여 기술한다. 개발된 시스템은 적외선 형상과 강도를 제어할 수 있도록 설계되어서 적외선 형상과 방사되는 강도가 실물 항공기와 유사하다. 본 논문에서 제시한 기술을 적용한 결과 완전가동 상태에서 실물항공기의 적외선열상 이미지와 같은 열상을 만드는데 오직 30㎾정도의 전력만을 소비됨을 확인하였다 성능실행시험 후에는 표적적응유도시험. 유도조종 로직시험 등과 같은 성능평가시험 단계를 통하여 본 논문에서 개발된 적외선 열상표적을 휴대용 대공유도무기의 표적으로 실용화하였다.

• 한국군사과학기술학회지
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• 제21권4호
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• pp.471-480
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• 2018

Accurate target coordinate is very important in military operations especially field artillery's ground-to-ground attack and air-force's air-to-ground attack. DOS(or TAS) is used to acquire target coordinates from long distance. DOS is comprised of LRF and goniometer. LRF measures distance between DOS and target. Goniometer is comprised of azimuth and vertical angular sensors, DMC and internal GPS receiver. DOS must set the position and orientation(finding grid north) before measurement step(target coordinate acquisition). To improve accuracy of target coordinate, VRS RTK and reference point method are proposed in DOS setup step. VRS RTK provides accurate location coordinate with small deviations, providing high accuracy and precision in positioning and orientation. As a result, horizontal coordinate(easting and northing) accuracy is improved from 2.68 mil(C.L. = 0.95) mil to 0.58 mil(C.L. = 0.95).

• 한국군사과학기술학회지
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• 제21권3호
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• pp.323-330
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• 2018

In this paper, design and fabrication of a MSP(Multiple Scattering Points) discriminator for a simulated target measurement using a HRR(High Range Resolution) RADAR are described. The MSP discriminator is designed to provide a reference signal at the installed point on the simulated target in an outdoor test. The MSP discriminator is designed to have a remote control function that can turn the MSP discriminator on and off when the target moves to a remote location. While the MSP discriminator is off, the MSP discriminator is designed to be small enough not to spoil the target's unique RCS. The MSP discriminator consists of RF components in the Ku-band. In order to prevent spreading of the signal, a cable were added to the MSP discriminator to have an appropriate feedback loop delay considering the resolution of the RADAR. The fabricated MSP discriminator provided a reference scattering point as an RCS of approximately 1 dBsm. As a result, by using the MSP discriminator, the physical scattering points of the target were clearly identified in the measured signals with the RADAR.

• 대한산업공학회지
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• 제27권2호
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• pp.190-196
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• 2001

This study aims to develop three types of the visual fields: stationary field, eye field, and head field, which are classified depending upon the eye and head movements. A visual experiment taking target size, target color, and meridian into account was conducted, in which the L32 orthogonal array was employed. The results showed that target size and meridian were significant at ${\alpha}$=0.01 in all three visual fields. Contrary to expectation, target color was significant at ${\alpha}$=0.10 only in the head field. Furthermore, the differences in size of the head field depending upon four target colors were negligibly small. Three linear regression models were provided to generate visual fields which are appropriate for given visual task's characteristics. In addition, a simple method using adjusting factor was also proposed so that anyone without knowledge for human factors/ergonomics can easily generate and use them when designing or evaluating visual tasks. It is expected that the visual fields presented in this study can be easily used even by non-ergonomic experts in real situations due to their simplicity.

• 디지털산업정보학회논문지
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• 제6권2호
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• pp.247-254
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• 2010

In this paper, I propose the modular support of IT small companies that assigns specialist on each module and create the module corresponding to R&D processes to small companies in order to support technical difficulties arising in a R&D process of IT small companies. The number of applied target companies is 149 IT small companies and altogether 45 specialist who had supported 10 modules. As a result of observing for two years, I identified that the system helps the technical difficulties.