• Asian Pacific Journal of Cancer Prevention
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• v.14 no.8
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• pp.4801-4804
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• 2013

Purpose: To investigate short-term response rate, quality of life and toxicities of mannan peptide combined with TP regimen in treating patients with non-small cell lung cancer (NSCLC). Patients and Methods: Forty one patients with NSCLC were divided into an experimental group treated with TP regimen combined with mannan peptide (21 patients) and a control group treated with TP alone (20 patients). Results: Response rates were 61.9% (13/21) for the experimental and 60% (12/20) for the control group (p>0.05). Regarding toxicity, white blood cell decreased more frequently in the control group (65%, 13/20) than in the experimental group (33.3%, 7/21) (p<0.05); nausea and vomiting also occurred more frequently in the control group (55%, 11/20 vs 23.8%, 5/21) (p<0.05). In terms of quality of life, this index was improved by 57.1% (12/21) and 25% (5/20) in experimental and control groups, respectively (p<0.05). Conclusions: Response rate of TP after combined with mannan peptide is mildly increased, while this combination alleviates bone marrow suppression as well as nausea and vomiting of TP, and improves quality of life when treating patients with NSCLC. However, this conclusion should be confirmed by randomized clinical trails.

• Clinical and Experimental Pediatrics
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• v.59 no.10
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• pp.414-420
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• 2016

Purpose: We investigated behavioral problems, attention problems, and cognitive function in children and adolescents born small for gestational age (SGA). Methods: Forty-six SGA children born at term and 46 appropriate for gestational age (AGA) children born at term were compared. Psychiatric symptoms were examined with reference to the Korean-Child Behavior Checklist, Korean-Youth Self Report, and Attention Deficit Hyperactivity Disorder Rating Scale (ADHD-RS). Cognitive function was estimated using the Wechsler Intelligence Scale. Sociodemographic data were recorded from interviews. Results: SGA children had high scores on delinquent behavior, aggressive behavior, and the externalizing scale, and they also showed a propensity for anxiety and depression. The SGA group had a higher mean ADHD-RS score than the AGA group ($10.52{\pm}8.10$ vs.$9.93{\pm}7.23$), but the difference was not significant. The SGA group had a significantly lower verbal intelligence quotient (IQ) than the AGA group, but the mean scores of both groups were within normal limits. Conclusion: This study indicates marked behavioral problems, such as delinquency, aggressiveness, and anxiety and depression, as well as low verbal IQ in the SGA group than in the AGA group. Even in cases in which these symptoms are not severe, early detection and proper treatment can help these children adapt to society.

• Journal of Physiology & Pathology in Korean Medicine
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• v.24 no.5
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• pp.814-821
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• 2010

The purpose of this study was to investigate effects of moxibustion at combined acupoints on sex and age in rats. This study measured the effects of moxibustion on small intestinal motility in rats. Cauterizing with moxa was applied 5 times to the acupoints on SI8, LI11 SP9 and ST36 under enflurane anesthesia in the groups divided with sex and age. In single acupoint groups, cauterizing with moxa on ST36 increased in all of sex and age groups. The SP9 group with 5, 6 weeks in female and 5, 8 weeks in male, the SI8 group with 5, 7 weeks in female and only 7 weeks in male, the LI11 group with only 5, 6, 7 weeks in female and only 7 weeks in male showed increasing on small intestinal motility. In combined acupoints groups, the SI8+SP9 group with 7 weeks in female and 5, 6, 8 weeks in male, the SI8+ST36 group with 5, 6 weeks in female and 8 weeks in male, the LI11+SP9 group with 5, 6 weeks in female and 6 weeks in male, the LI11+ST36 group with 5 weeks in female and 5, 6, 7 weeks in male showed increasing respectively. Although these different according to the sex and age in rats do not have a established tendency, the results suggested that the effects of combined acupoints of cauterizing with moxa have relation with individuality.

• Journal of Korean Neurosurgical Society
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• v.46 no.2
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• pp.109-115
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• 2009

Objective: The decision to adopt a conservative or surgical modality for a relatively small volume of spontaneous intracerebral hemorrhage (SICH) is difficult and often controversial, especially when consciousness is tolerable. The authors examined the results of stereotactic-guided evacuation of SICH for relatively small volumes with respect to functional outcome. Methods: This prospective study was performed on 387 patients with SICH who underwent stereotactic-guided evacuation (n = 204, group A) or conservative treatment (n = 183, group B) during the past 8 years. The primary end-point was recovery of functional status, which was estimated using the Modified Barthel Index (MBI) and the modified Rankin Scale (mRS). Results: All patients had a Glasgow coma scale (GCS) score of $\geq$ 13 and unilateral hemiparesis of less than motor power grade 3. Group demographic characteristics and initial neurological statuses were similar. In all cases, the volume of SICH involved was < 30 cm$^3$ and location was limited to basal ganglia and thalamus. At 6-month follow-ups, MBI was 90.9 in group A and 62.4 in group B (p < 005), and MRS was 1.2 in group A and 3.0 in group B (p < 0.05). Better motor function and stereotactic-guided evacuation had a significant effect on a functional recovery in regression analyses. Conclusion: Even in patients with a small volume of SICH, stereotactic-guided evacuation improved functional recovery in activities in daily life than conservative treatment did.

• Clinics in Shoulder and Elbow
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• v.18 no.3
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• pp.144-151
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• 2015

Background: The consensus is that a bony Bankart lesion shorter than 25% of the length of glenoid does not affect the clinical result; hence, such lesions were often neglected. However, small bony Bankart lesions are associated with various types of capsulolabral lesions. Methods: A total of 82 patients who had undergone arthroscopic capsulolabral lesion repair surgery for anterior shoulder dislocation were reviewed. The prevalence rates of early and late type of capsulolabral lesions were compared between a group of patients with and a group without small bony Bankart lesions. In addition, the types of accompanying capsulolabral lesion were analyzed according to the type of bony Bankart lesion. Finally, the clinical outcomes were evaluated (active range of motion, American Shoulder and Elbow Surgeons score and Rowe's score). Results: Among the 13 patients who had small bony Bankart lesions, the prevalence rate of early and late type of capsulolabral lesions was 38.5% and 61.5%, respectively. Among the 69 patients without bony Bankart lesion, the prevalence rates of early and late type of capsulolabral lesions were 74% and 26%, respectively. Significantly worse clinical outcome was observed for the group of patients with both small bony Bankart lesions and late type of capsulolabral lesion. Conclusions: More severe type of small bony Bankart lesion appears to be associated with late type of capsulolabral lesion. The significantly worse clinical outcome for patients with both small bony Bankart lesion and late type of capsulolabral lesion indicates that small bony Bankart lesions cannot always be neglected.

• Proceedings of the Korean Geotechical Society Conference
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• 2000.03b
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• pp.387-394
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• 2000

In the present study, laboratory pull-out tests with screw anchors are carried out to investigate behavior characteristics of underground structures applied uplift seepage forces. Small scaled pull-out tests in sand were conducted under saturated condition. And then, it was observed that the upward displacement as well as the pullout load varied with spacing of the anchor. Also, analyses have been performed with the aim of pointing out the effects of various parameters on the group effect of the screw anchors.

• Knowledge Management Research
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• v.12 no.1
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• pp.91-110
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• 2011

The purpose of this study is to identify the impact of IT group efficacy of small business using B2B e-commerce on organizational performance. First, we conceptualized IT group efficacy, based on theories in regard to group efficacy, absorptive capacity, and electronic information sharing. And then we examine that IT group efficacy of small business setting up IS and performing B2B e-commerce increases absorptive capacity and electronic information sharing, and ultimately improves organizational performance. The result is that IT group efficacy has a significant positive effect on absorptive capacity, but doesn't have a significant positive effect on electronic information sharing. Also absorptive capacity has a significant positive effect on electronic information sharing and organizational performance, and electronic information sharing has a significant positive effect on organizational performance. Finally, we discuss about the limits and directions as well as the results and implications of this study.

• Asia pacific journal of information systems
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• v.10 no.1
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• pp.1-18
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• 2000

One stream of the GDSS(Group Decision Support System) research is to investigate how GDSS affects decision performances of small groups according to task types, support features, meeting facilitation modes and meeting environments. But little study has investigated the effects of group member characteristics on group decision processes and outcomes depending upon whether GDSS is provided or not. To date, most GDSS studies have not controlled group member characteristics(e,g. personality, sex, decision style) in laboratory experiments. However, this study included the decision styles of group members as an independent variable. Therefore, this study investigated how differently members of two different decision styles perceive the use of GDSS in small group meetings through lab experiments. The two decision styles are feeling(F) style and thinking(T) style. We found that the effect of GDSS is a function of individual's decision style only in the communication thoroughness variable. The decision style is a statistically significant factor that can mediate the effects of the group support technology on the perceived communication thoroughness. Specifically, the GDSS is positively related to participants' perception about satisfaction on decision process, goal achievement, communication thoroughness, degree of influence-outward and effort for achieving meeting goals.

• Journal of Korean Elementary Science Education
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• v.26 no.1
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• pp.1-11
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• 2007

The purpose of this study was to investigate interaction patterns and characteristics of small group discussions during elementary school science classes. Four heterogeneous groups were formed according to preferences and non-preferences, consisting of male and female students. Verbal interactions during small group discussions were audio and videotaped, transcribed and analyzed. The interaction frequency of each group was compared in terms of their cognitive and affective aspects. The results in terms of the cognitive aspect showed that there were no significant differences in the frequency of interaction between preference and non-preference groups' verbal behaviors. However, the quality of interaction was superior and the number of high level types of interaction were more frequent in the preference group. From the affective perspective, both groups of students exhibited a positive attitude in the preference group and a negative attitude in the non-preference group. The differences of interaction between the male and female student's groups were that in the case of the female group, the frequency and the quality of interaction was higher. Moreover, in contrast to male students, female students revealed satisfaction and favorable attitudes in their non-preference group because they felt more a acceptable atmosphere and attitude in that group. These results suggest that the interactions of the preference group are more interactive and elaborate in nature than those of the non-preference group.

• Journal of Chest Surgery
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• v.50 no.6
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• pp.415-423
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• 2017

Background: Recently, many surgeons have chosen sublobar resection for the curative treatment of lung tumors with ground-glass opacity, which is a hallmark of lepidic lung cancer. The purpose of this study was to evaluate the oncological results of sublobar resection for non-lepidic lung cancer in comparison with lobectomy. Methods: We conducted a retrospective chart review of 328 patients with clinical N0 non-small cell lung cancer sized ${\leq}2cm$ who underwent curative surgical resection from January 2009 to December 2014. The patients were classified on the basis of their lesions into non-lepidic and lepidic groups. The survival rates following lobectomy and sublobar resection were compared within each of these 2 groups. Results: The non-lepidic group contained a total of 191 patients. The 5-year recurrence-free survival rate was not significantly different between patients who received sublobar resection or lobectomy in the non-lepidic group (80.1% vs. 79.2%, p=0.822) or in the lepidic group (100% vs. 97.4%, p=0.283). Multivariate analysis indicated that only lymphatic invasion was a significant risk factor for recurrence in the non-lepidic group. Sublobar resection was not a risk factor for recurrence in the non-lepidic group. Conclusion: The oncological outcomes of sublobar resection and lobectomy in small-sized non-small cell lung cancer did not significantly differ according to histological type.