• Journal of Physiology & Pathology in Korean Medicine
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• v.24 no.6
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• pp.1062-1067
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• 2010

The purpose of this study was to estimate skin care effect of Miso Facial Rejuvenation Acupuncture with the facial skin photographing system and ultrasonography. 4 Patients who made first visits to Daegu Oriental Hospital of Daegu Hanny University from August 7, 2009 to August 12, 2009 were each given five-times treatments of Miso Facial Rejuvenation Acupunture. The facial skin photography of each participant was checked two times-pretreatment, posttreatment-using the facial skin photographing system and ultrasonography. The squares and counts of 2parts of facial winkles and thickness of masseter muscle were measured for each one. The squares and counts of facial wrinkles were decreased. The thickness of masseter muscle were decreased. On this study, we could evaluate the wrinkle treatment effects and reduction of masseter muscle of Miso Facial Rejuvenation Acupuncture by an objective method. Miso Facial Rejuvenation Acupuncture has notable effect in wrinkle treatment and reduction of masseter muscle. As though we had not wide experience in this treatment, more research is needed.

• Textile Coloration and Finishing
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• v.25 no.4
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• pp.271-278
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• 2013

In order to investigate the effect of gallotannin treatment to ceramide-containing fabrics on atopic skin diseases, the agglomeration of standard protein BSA and the deactivation of model enzyme were examined. The gallotannin treated on ceramide-containing fabrics precipitated the standard protein, BSA, and therefore deactivated the model enzyme by 70% at 6% treatment concentration. Wash durability should be improved after around 5 cycles of washing. Clinical test of the gallotannin-treated fabrics was carried out on mice for two test items, transepidermal water loss assay and severity score of diseased skin of mice. The results showed significant level of improvement of atopic skin diseases compared with the negative controled.

• Journal of Veterinary Clinics
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• v.36 no.4
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• pp.219-224
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• 2019

The aim of this study was to evaluate the safety and effects of a soy lecithin-based supplement on the general health, skin condition, and blood lipid levels of dogs. Twenty-five, healthy, privately-owned dogs were enrolled in the study. Oral supplementation was administered for 8 weeks in the treatment group. Evaluation items included a thorough physical examination, owner responses to a questionnaire, blood analysis (CBC, CRP, serum chemistry, lipid profile). The results showed a significant improvement in amount of exercise, water intake, skin exfoliation in the treatment group (P < 0.05) but no significant changes in the other evaluation items, including no significant changes in blood component results following administration of the supplement. Most dogs well tolerated the treatment, and there were no serious adverse events. We suggest that soy lecithin has potential as a nutraceutical for the positive effect of general health condition such as activity and skin condition. Further studies are needed to establish the appropriate dose level and administration frequency of soy lecithin in dogs.

• Journal of Environmental Health Sciences
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• v.27 no.4
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• pp.73-78
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• 2001

Hair will be persuit of beautifulness of human being in various permanent wave by many kinds of its drugs. Skin is based upon the hair which enroll the body of high living animals and have multiple membrane structure In this study used rat the effects of commercial permanent wave products to skin which are composed with L- cysteine and bases Results are as follow: the content of penetration 4 hors later with steady state and no significant changeable after 20 hours later. In cysteine groups, lag time and permeability coefficient of healthy skin is 2.22hr and 0.13$\mu\textrm{g}$/㎥ hr, lag time and permeability coefficient of old skin is 4.01 hr and 0.108 $\mu\textrm{g}$/㎥ hr . In conclusion of study lag time and permeability coefficient in old skin and wounded skin are faster than healthy skin. We notified that fine rinkle and rash of skin were changeable in the case of treating with permanent wave drugs than normal skin.

• Journal of Platform Technology
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• v.10 no.3
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• pp.3-10
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• 2022

The effectiveness of an innovative skin treatment system that delivers an anti-aging solution deep into the skin without invasiveness and pain using a non-invasive air technology was investigated. In addition, an effective change using a non-invasive technique for delivering a solution for skin improvement was confirmed. The equipment named Cellre Jet is an effective skin care and drug delivery equipment that instantly opens the skin epidermis by using a maximum output pressure of 6 bars and high-pressure purified oxygen of 75-90% purity to deliver various nano-sized vital substances deep into the skin, and it uses the method of precisely controlling the equipment through an 8-inch digital touch display to accurately dispense the prescribed dosage. In this study, changes in skin condition were analyzed using this equipment and nano ampoules on subjects with actual skin problems through a related comparison and effectiveness judgment program. Through this study, skin care and drug delivery are possible, which will contribute to verifying the effectiveness of this non-invasive drug delivery equipment in the future, and is expected to establish the systematic effect in observing and studying changes in the skin.

• Environmental Analysis Health and Toxicology
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• v.23 no.1
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• pp.63-65
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• 2008

The tissue distribution of $TiO_2$, nanopaprticles was investigated in mice after oral administration, and skin treatment. Male mice were treated with the dose of 5 g/kg of $TiO_2$ for three consecutive days and sacrificed at 24 hours after the last administration. As results, the orally administered $TiO_2$ nanoparticels were shown to be distributed in the testis, lung, and brain at 24 hours after the last treatment. Kidney does not seem to be the main target of $TiO_2$ nanoparticle distribution. It means that $TiO_2$ nanoparticles (17 nm) are easily absorbed through entero-gastric system and may cause toxicity in brain, lung, and reproductive organs. The distribution of skin treatment showed the same pattern like oral administration.

• Journal of Acupuncture Research
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• v.29 no.4
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• pp.105-111
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• 2012

Objectives : An objective measurement for the effects of acupuncture therapy had been regarded as one of the important agendas in the research of acupuncture. This case report aimed to measure the changes of blood flow on the skin flap after one session of electroacupuncture treatment. Methods : A 27-year-old male patient was treated with ipsilateral or contralateral electroacupuncture on the $LI_{11}$, $LU_{10}$, $LI_{10}$, $TE_5$, $SI_3$ and Ex- $UE_9$(Palsa) in the arm with the skin flap on dorsal region of the hand. Changes of blood perfusion on the skin flap and opposite dorsum of hand were measured with laser Doppler blood perfusion imager(LDPI). Results : Immediate post-treatment relative changes of the blood perfusion on the skin flap and opposite hand after one session of ipsilateral electroacupuncture was 21% and 18% higher than values from pre-treatment assessment, respectively. On the contrary, when needled contralaterally, relative changes of the blood perfusion on the affected and unaffected hand was 7% lower and 22% higher than values from pre-treatment assessment, respectively. Mean differences of the blood perfusion between on the skin flap and on control hand remained similar after the ipsilateral acupuncture treatment but substantially increased(44.58 of perfusion units). Conclusions : Electroacupuncture may alter the local blood flow on the skin flap. More study is needed to investigate the effects of acupuncture on the blood flow and microcirculation on the skin tissue by well-designed clinical and experimental studies.

• Journal of Korean Academy of Nursing
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• v.4 no.3
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• pp.93-104
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• 1974

Regardless of a patient's diagnosis, the care of his skin has been a primary concern of nurses throughout the years. Nurses has washed, dried, and rubbed the skin and have changed his position so as to keep the patient's skin in good condition and to protect him from pressure sores. However, we still find many-patients suffering from the pressure sores which may take many mothers or years of treatment and cost a lot to be repaired. In view of expensive cost for treatment of the sores and low ratios of nursing staff per patient for intensive nursing care, prophylaxis of the bed sores with sufficient aids is extremely important both for patients and for nurses. Therefore, the unique purpose of this study was to determine whether sponge is good enough to treat and prevent the pressure sore as compared with gel pad and sheepskin. Sixty patients in the age range of 15 through 45 who were in unconscious status or have difficulty of mobility were chosen between January and March of 1974 at Seoul National University Hospital. They were randomly assigned to each treatment and observed on every 4th day with regard to level of consciousness, status of mobility, moisture or dryness of the bed, general skin condition, intake of nutrition, vital signs and intervals of position change in comparison with the changes of skin over the bony prominences. The study results were reviewed in a statistical method analysis of valiance-to obtain the following findings: 1. There was no significantly different changes of skin over the sanctum or the trochanter in each group using get pad, sheepskin or sponge. It means that we may substitute sponge for expensive gel pad or sheepskin. 2. There was no significant difference among mean changes of patient's skin in relation to sheepskin, gel pad and sponge. 3. There was no significant changes of patient's akin in relation to level of consciousness, status of mobility, intake of nutrition, general skin condition, temperature, blood pressure or interval of position change. 4. There were no meaningful interactions between each treatment and level of consciousness, moisture or dryness of the bed, intake of nutrition, general skin condition, temperature or blood pressure. 5. Sheepskin and gel pad had significantly better influence on patients with limited mobility than on patients with immobility, and sponge on patients with immobility on than patients with limited mobility, 6. Sheepskin and sponge had meaningfully totter influence on patients changing position at below 2-hour interval, gel pad at 2-4-hour interval, sheepskin at 4-6-hour interval, and three of them at above 6-hour interval.

• Journal of the Society of Cosmetic Scientists of Korea
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• v.38 no.4
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• pp.321-326
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• 2012

Recent studies have revealed that collagen peptide plays a protective role on skin by improving the activity of antioxidants and acts as an inducer of skin regeneration. To evaluate the efficacy of low molecular weight collagen peptide for skin recovery after non-ablative 1550 nm fractional photothermolysis laser. 10 volunteers were randomly divided into two groups. Both control and experimental groups received fractional photothermolysis treatment. In the experimental group, 5 subjects received oral collagen peptide 1,000 mg/day for 8 weeks. Before and after the treatment, we measured elastic recovery of skin, transepidermal water loss (TEWL) and erythema index (EI) for each patients. The evaluation of clinical results showed that elastic recovery of skin is higher in the experimental group than the control group (p < 0.05). TEWL have no significancy between two groups and erythema rapidly disappeared in the experimental group. On the quartile grading scale, the mean patient satisfaction 4 weeks after the fractional photothermolysis treatment was 2.0 in experimental group and 1.2 in control group. The low molecular weight collagen peptide appears to be an effective conservative therapy for skin recovery after non-ablative 1550 nm fractional photothermolysis treatment.

• Journal of Pharmaceutical Investigation
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• v.24 no.3
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• pp.41-47
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• 1994

The effect of Azone and ethanol on the electrical properties of human and hairless mouse skin was studied and the results were compared. The complex electrical impedance was measured as a function of frequency, and resistance and capacitance were determined from Nyquist plot. After the treatment of human-heat separated epidermis with Azone, contrary to the expectation, resistance increased about 60% and it did not change with time. Capacitance also increased; immediately after the treatment, it was about 110% of pretreatment value and it increased further with time. On the other hand, when hairless mouse skin was treated with Azone, marked changes occured; resistance fell almost to the value of bathing medium itself and capacitance increased to about 200% of its pretreatment value. Similar result were obtained when hairless mouse skin was treated with 100% ethanol. The results suggest that there are differences in the strength of barrier properties of stratum corneum (SC) between human and hairless mouse skin. Overall, the results provide further mechanistic insight into ion conduction through the skin and into the role of SC lipids in skin capacitance.