• 한국전자파학회논문지
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• 제16권8호
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• pp.810-814
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• 2005

TEM 셀 내에 있는 혈액에 대한 삽입 손실과 반사율을 측정하여, 원하는 혈액 흡수 SAR(Specific Absorption Rate) 선택에 따른 TEM셀 입력 전력을 구하였다. 혈액 세포는 피부 세포와 함께 전자파 영향을 연구하기 위한 기준 세포이다. 따라서 SAR에 따른 혈액 세포에 인가할 전력 산출은 정확해야 함은 물론 타당성이 있어야 한다. 이 연구에서는 g당 혈액 세포가 받는 전력을 산출하기 위해 50 g의 혈액을 이용하여 전달 전력 감소를 측정하였다. 측정된 데이터로부터 휴대폰 전자파 생체 흡수율 SAR 0.8, 1.6, 3, 4 mW/g에 해당하는 TEM셀 입력 전력을 계산하였다. 이 연구 결과는 배양 세포의 전자파 방사 장치에 응용함을 목적으로 하고 있다.

• Asian-Australasian Journal of Animal Sciences
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• 제24권7호
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• pp.912-918
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• 2011

Newly born lambs have to face challenges in a new environment totally different from that of the uterus. Adaptation to extra-uterine life involves functional changes with almost each organ and system in the body undergoing a series of metabolic and anatomical modifications. Failure to adapt the extra-uterine environment can not only lead to homeostatic disturbances but also lead to the death of the affected lambs. Hematological parameters of newly born lambs show variability that differs between breeds of lambs. The purpose of present study was to determine homeostatic responses and physiological reference values in Kajli breed lambs occurring in the neonatal period through changes in blood profile, respiratory rate, heart rate, live weight and rectal, scrotal and skin temperatures. For this purpose, sixteen clinically fit lambs (males = 10 and females = 6) with a mean body weight $6.92{\pm}0.46$ kg were selected. Physiological data of selected parameters of each Kajli lamb was recorded at three day intervals and hematological parameters at five days for a period of 30 days. In general, statistical analysis showed a significant effect of time (p<0.001) on all the studied physiological and hematological parameters except platelets counts, white blood cells and hemoglobin concentration. The results documented in the current study are an addition to existing knowledge of the physiology of Kajli sheep breed should be helpful in developing feeding, disease diagnoses and treatment protocols for newborn Kajli stock.

• Journal of Acupuncture Research
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• 제28권2호
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• pp.49-55
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• 2011

Objectives : This study was to develop programmable and rechargeable electronic moxibustion device as an interdisciplinary research focusing on traditional Korean medicine. Methods : This device deployed several advances on safety and conveniences with the advantage of programmable heat stimulation, heating material and recharging method. The gradient of heat stimulation was programmed with the reference of previous studies and own measurements. The heat curve reached its efficacious stimulus temperature after three minutes, and maintained until 13 minutes with $42^{\circ}C$. We also incorporated feedback from field hospital experiences with the help of hospital staffs. Results : This device can prevent damages from skin burn and fire accidents, and control the smoke, smell and residue of moxa itself. Conclusions : This study will contribute for the development and improvement of efficacious and safe treatment methods for the traditional Korean medicine.

• 대한한의진단학회지
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• 제15권3호
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• pp.235-244
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• 2011

Objectives: There are four types of diagnostic methods in Oriental medicine, and visual inspection is the first method among them. This study was written in order to complement further understanding on visual inspection. Methods: The authors reviewed a word related with visual inspection in Nei-Ching. The authors researched static words such as bigger/smaller, longer/shorter, slower/faster, curved/straight, one-sided/fair, and groove/uplift, and active words such as extension and contraction, shake, tremor, slow, fast, walk, run, standing, lying, and sitting related with visual inspection in Nei-Ching. Results: The static words linked with visual inspection are related with skin, muscles, fat, and especially the liver, stomach, and large intestine. The active words linked with visual inspection are related with movement of muscles, fat, and bone. Conclusion: In this study, the authors provided further understanding on visual inspection in Nei-Ching. However, there was no clear reference point about appearances and movements.

• Smart Structures and Systems
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• 제17권5호
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• pp.819-835
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• 2016

In this paper, the activities carried out within the EU funded Clean Sky Joint Technology Initiative (JTI GRA) Project and aimed at developing a morphing flap, are illustrated. The reference device is a regional aircraft single slotted flap, enhanced with deforming capabilities to obtain improved hyper-lift performance. The design started with the identification of the internal architecture, intended to allow camber variations. A concentrated-hinge architecture was selected, for its ability to fit different curvatures and for the possibility of easily realizing an "armadillo-like" configuration, then avoiding the use of a complicate deformable skin. The flap layout is made of segmented ribs, elastically hinged each other and span-wise connected by conventional spars. Relative rotations of the rib elements are forced by SMA structural actuators, i.e., cooperating in the external loads absorption. Super-elastic SMA are used to make up recovery elastic elements, necessary to regain the original shape after activation. These further elements in turn contribute to the overall flap rigidity. After assessing the hinge number and the size of the SMA active and passive elements, the advanced design phase was dealt with. It was aimed at solving manufacturing issues and producing the executive drawings. The realized demonstrator was finally tested in lab conditions to prove its functionality in terms of whether target shape actuation or attained shape preservation under loads. On the basis of the numerical results and the experimental outcomes, precious hints were obtained for further developments of the concept.

• 대한화장품학회:학술대회논문집
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• 대한화장품학회 2003년도 IFSCC Conference Proceeding Book I
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• pp.192-202
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• 2003

The wrinkles correspond to the most obvious expression of skin ageing and are manifested by changes on the organization and dermal structure. In the extracellular matrix, decreased quantities of collagens and glycosaminoglycans as well as a deterioration of the fibrillary network is noted, result in a reduction of dermal thickness. In addition, the activity of the collagenases increases in contrast to the synthesis of collagen fibers. Nor are cells spared during the aging process. We thus studied and compared the contractile capacity as well as the synthesis capacity of normal human fibroblasts and human fibroblasts obtained from biopsies of forehead wrinkles. The capacity of the fibroblasts to be adhered to the collagen network and to maintain a three-dimensional structure of dermis was studied on a model of equivalent dermis. The metabolic activity was studied by evaluating the capacities of synthesis of collagen I, main component of dermis. Human fibroblasts resulting from the forehead wrinkle contract less the gel of collagen than the normal human fibroblasts and present an activity of biosynthesis of collagen I less important than normal human fibroblasts. These results show that fibroblasts with aging present a deceleration of their metabolic activity and lose their capacity of adhesion to collagen fibers thus limiting the possibility of organizing the dermal tissue. We investigated the potential of an active ingredient able to compensate for the reduction of the metabolic activity and to restore the contractile capacity of fibroblasts obtained from forehead wrinkles. This effect was compared with a reference molecule: the vitamin C.

• 대한전자공학회논문지SP
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• 제41권6호
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• pp.61-71
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• 2004

얼굴검출을 위한 다양한 연구가 행해지고 있으나 아직도 실시간성의 확보는 미진하다. 이에 본 연구는 연속영상에서 컬러와 움직임 정보를 이용한 실시간 얼굴검출 방법을 제안한다. 피부색 검출을 위한 컬러공간은 조명의 변화에 강인하고 피부색을 좁은 영역으로 정의할 수 있는 Hue와 Cr성분을 조합하여 재구성한 HCr을 사용한다. 배경참조영상 기반에서 밝기와 Cr 성분을 함께 사용하여 획득한 움직임 영역에서, HCr과 적응적 임계값을 이용해서 피부색 영역을 검출하고, 그 검출된 영역의 모양과 크기정보를 통해 얼굴 후보영역을 구한다. 이렇게 구해진 얼굴후보영역에서 G와 B성분의 차이, 밝기, Cr성분 값과 눈과 입의 위치 및 거리관계를 이용하여 눈과 입을 검출하여 얼굴을 확정한다. 실험결과 연속영상에서 실시간으로 얼굴을 검출 할 수 있었다.

• 전자공학회논문지CI
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• 제49권1호
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• pp.1-7
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• 2012

최근 새롭게 연구되는 심전도기반 바이오인식은 통상 고가의 심전도 측정 장비를 필요로 하고 측정방법에도 제한이 많아 실제 인식시스템으로 사용하기 위해서는 극복해야할 문제들이 많은 실정이다. 이에 본 논문에서는 심전도 바이오인식용 심전도 측정 하드웨어를 제작해 심전도 리드 I 파형을 이용한 바이오인식 시스템을 개발했다. 제작된 하드웨어는 측정자의 동적인 측정환경 및 파형왜곡 최소화를 고려해 설계된 필터가 적용되었고, 기준접점을 제거해 두 개의 전극만으로도 심전도 측정이 가능하도록 설계되어 측정자의 거부감을 줄일 수 있다. 제작된 하드웨어를 기반으로 17명의 측정자로부터 심전도 리드 I 파형을 수집했으며, 파형 추출 알고리즘을 개발해 각각의 단일 심전도 파형으로 분리했다. SVM(support vector machine) 분류기를 이용한 심전도 바이오인식 실험결과 민감도(sensitivity, SN) 98.59% 및 정확도(accuracy, ACC) 97.21% 의 성능을 보였다. 개발된 심전도 바이오인식 기술은 기존 심전도 바이오인식 대비 사용 편의성을 높였으며 저가의 하드웨어로 구현 가능하다.

• 대한전자공학회:학술대회논문집
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• 대한전자공학회 2009년도 정보 및 제어 심포지움 논문집
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• pp.357-359
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• 2009

In this paper, the 2.4GHz doppler radar system consisting of the doppler radar module and a baseband module were designed to detect heartbeat and respiration signal without direct skin contact. A bio-radar system emits continuous RF signal of 2.4GHz toward human chest, and then detects the reflected signal so as to investigate cardiopulmonary activities. The heartbeat and respiration signals acquired from quadrature signal of the doppler radar system are applied to the pre-processing circuit, amplification circuit, and the offset circuit of the baseband module. ECG(electrocardiogram) and reference respiration signals are measured simultaneously to evaluate the doppler radar system. As a result, the respiration signal of doppler radar signal is detected to 1m without complex digital signal processing. The sensitivity and calculated from I/Q respiration signal were $98.29{\pm}1.79%$, $97.11{\pm}2.75%$, respectively, and positive predictivity were $98.11{\pm}1.45%$, $92.21{\pm}10.92%$, respectively. The sensitivity and positive predictivity calculated from phase and magnitude of the doppler radar were $95.17{\pm}5.33%$, $94.99{\pm}5.43%$, respectively. In this paper, we confirmed that noncontact real-time heartbeat and respiration detection using the doppler radar system has the possibility and limitation.

• 한국응용약물학회:학술대회논문집
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• 한국응용약물학회 2001년도 추계학술대회 및 정기총회
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• pp.82-82
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• 2001

Previously, several prenylated flavonoids having a C-8 lavandulyl moiety were found to inhibit cyclooxygenase-1 (COX-1) as well as 5-lipoxygenase (5-LOX), and sophoraflavanone G was the most potent inhibitor against these eicosanoid generating enzymes among the prenylated flavonoids tested. In this investigation, effects of sophoraflavanone G on COX-2 induction from RAW 264.7 cells and in vivo inflammatory response were studied. Sophoraflavanone G inhibited prostaglandin E$_2$(PGE$_2$) production from lipopolysaccharide (LPS)-treated RAW cells by COX-2 down-regulation without significantly affecting COX-2 activity at 1 50 $\mu$M. Other prenylated flavonoids including kuraridin and sanggenon D also down-regulated COX-2 induction at 10-25 $\mu$M, lirhile kurarinone and echinoisoflavanone did not. In addition, sophoraflavanone G shelved in vivo anti-inflammatory activity against mouse croton oil-induced ear edema and rat carrageenan paw edema via oral (2-250mg/kg) or topical administration (10 - 250 $\mu\textrm{g}$/ear). Although the potencies of inhibition were far less than that of a reference drug, prednisolone, this compound showed higher anti-inflammato교 activity when applied topically, suggesting a potential use for several eicosanoid-related skin inflammation such as atopic dermatitis.