• Title/Summary/Keyword: Skin Test

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Experimental Debonding Failure Behaviors of Composite Skin-Stiffener Bonded Specimens (복합재료 스킨-보강재 접합 시편의 파손 특성에 대한 시험 연구)

  • Kim, Kwang-Soo;An, Jae-Mo;Jang, Young-Soon;Yi, Yeong-Moo
    • Composites Research
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    • v.20 no.6
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    • pp.8-14
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    • 2007
  • Debonding failure characteristics of the composite skin-stiffener specimens were experimentally investigated. The influences of bonding methods, types of stiffener shape and various secondary bonding parameters were evaluated. Present test results combined with the previous test results[1] showed that the failure displacement of the skin-stiffener specimens well evaluates the skin-stiffener debonding failure strength of the composite stiffened panels. The specimens with an open type stiffener had lower bending stiffness and larger failure displacement than those with a closed type stiffener. Secondary bonding and co-curing with adhesive had better failure strength than co-curing without adhesive film. Secondary bonded specimens failed by adhesive failure and co-cured specimens failed by delamination failure. As the bondline thickness was thinner, the skin-stiffener specimens had higher failure strength. The fillets had no influence on failure strength of the specimens. The influence of the surface roughness was shown according to types of stiffener shape.

Clinical Study of Cream Containing Pueraria mirifia for Skin Elasticity (Pueraria mirifica 추출물 함유 화장품의 피부 탄력 임상 효능 평가)

  • Kim Bora;Jung Sung Won;Lee Joo Dong;Ryoo Hee Chang;Cherdshewasart Wichai
    • Journal of the Society of Cosmetic Scientists of Korea
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    • v.30 no.3 s.47
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    • pp.385-388
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    • 2004
  • Recently, along with the remarkable increase in interest in natural products, the application of phytoestrogens in anti-aging products has become very important. In the focus, we developed Pueraria mirifica (PM), in this in vivo study on skin elasticity and wrinkles, and investigated the anti-aging properties. Thirty healthy women volunteers, between the ages of 30 and 60, applied the cream formula with $4\% Pueraria mirifica or placebo, on the face area twice a day for 16 weeks. The evaluation was made by silicon replica analysis, Cutometer SEM 575 and Comeometer followed by statistical treatment using the student's t-test. Results of skin elasticity measurement showed that topical application on the skin increased the total surface of skin elasticity in comparison with placebo group (p<0.05). However, PM cream does not have prominent effect on the depth of wrinkles and skin moisturization. This in vivo study demonstrates that, PM exhibits a significant effect on skin elasticity therefore, is of great interest in anti-aging and firmness skin care products.

A Case Study on Application of Bi-directional Pile Load Test for verifing the Bearing Capacity of a Large-diameter Drilled Shaft Pile (자갈층에 근입된 대구경 현장타설말뚝의 지지능력 확인을 위한 양방향 재하시험 적용사례)

  • Lee, Min-Hee;Jung, Sung-Min;Kim, Sang-Il;Choi, Yong-Kyu
    • Proceedings of the Korean Geotechical Society Conference
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    • 2006.03a
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    • pp.506-513
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    • 2006
  • In this study, multi-level hi-direction pile load tests for drilled shaft pile socketed into the gravel were performed. The lower and upper hi-direction load test assemblies were located on tip of pile and 15m above the tip of pile. Based on the results of pile load test, it was analyzed bearing capacity of gravel, skin firction of upper soils and skin friction of lower soils. It was confirmed that drilled shaft socketed into the gravel had enough bearing capacity.

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The Importance of Food Open Challenge Test in Atopic Dermatitis: The Comparison of Allergy History, Skin-Prick Test, and Specific IgE Detection

  • Noh, Geun-Woong;Ji, Eun-Jung;Park, Jung-Nan;Kim, Kyung-Hee;Do, Min-Hee;Lee, Eung-Kyung;Lee, Sang-Sun
    • Nutritional Sciences
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    • v.2 no.2
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    • pp.119-124
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    • 1999
  • Food allergies play an important role in Atopic Dermatitis (AD). Dietary manipulation is essential in the management of AD. However, there has been a paucity of data reporting the prevalence of food allergies in AD patients in Korea. In this study, the Food Open Challenge Tests (FOCT) were conducted to investigate food allergies in AD patients. The skin-prick test and the detection of specific IgE, as well as allergy history of patient were used to detect food allergies in all AD patients. Elimination diet was conducted for two weeks prior to FOCTs. The prevalence of food allergies by FOCT is as follows: milk (67.3%); chicken (64.2%); pork (62.8%); eggs (61.0%); beef(55.4%) ; wheat (52.0%) and soybean (45.2%). Allergenic food items in Korean AD patients were different from people in other foreign countries. The seven major foods those tested positively by FOCTs were completely eliminated from the replaced diets for two weeks, and were subsequently reintroduced one at a time. Results from FOCTs were not comparable with allergy history or skin-prick tests or specific IgE detection. The sensitivity and specificity of skin-prick tests and specific IgE detection were lower than FOCTs. Allergy history, skin-prick tests, and specific IgE detection are useful for the identification of food allergen but its clinical significance differed according to food items. Therefore, we conclude that even though a 10-day delay was necessary after food challenge, FOCT is a useful and valid method to confirm food allergies and may be essential for the effective control of food allergies for treatment of AD.

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Clinical Statistics on the Allergic Skin Tests in Seoulites (서울지역 일반인의 알레르기 피부시험에 관한 고찰)

  • 조재훈;김찬중;남봉수;한은정;김윤범
    • The Journal of Korean Medicine
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    • v.22 no.4
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    • pp.29-36
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    • 2001
  • Objectives: This study attempted to investigate the allergic histories and the distribution of offending allergens in the general public and further to help their diagnosis and treatment with Oriental Medicine. Methods: Allergic skin tests (AST) were performed and allergic histories were taken of 359 members of the general public who visited the International Exhibition on Oriental Medicine from Sept. 1 to Sept. 5, 2000. The allergen reagents for AST were three (House dust, D. farinae, Dog hair) and the control reagent was histamine solution. Results: 1.50.1 % of the subjects (n=359) were positive to AST. The ratio between males' positivity and females' was 1.06:1. 2. The younger the subjects were, the higher the positivity was. 3. The positive subjects' (n=180) positivity to three allergens was as follows: D. farinae 98.9%, House dust 30.0%, Dog hair 1.7%. 4. The younger the positive subjects were, the higher the positivity to House dust was. In contrast, the positivity to D. farinae was high in all age groups. 5.71.1 % of the positive subjects reacted positively to monotype allergen and 28.9% reacted positively to multiple allergens (2.46:1). The most common monotype allergen was D. farinae (98.4%) and the most common combination of multiple allergens was House dust and D. farinae (94.2%). 6.52.8% of the positive subjects (n=180) and 51.4% of the negative subjects (n=179) represented the history of allergic diseases. There was no relationship between allergic skin test and allergic diseases. Conclusion: To help in diagnosis and treatment with oriental medicine, research to analyze the relationship between allergic skin test and allergic diseases should be continued on the basis of Oriental medical theories.

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The Efficacy of Ampule Containing Herbal Extract for Improving Skin Wrinkles in Women (한약재 추출물 함유 앰플의 주름개선 효능에 관한 기초 임상연구)

  • Do, Eun-Ju;Lee, Jin-Sang;Park, Hyun-Jin;Ha, Il-Do;Kim, Young-Chul;Kim, Mi-Ryeo
    • Herbal Formula Science
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    • v.17 no.2
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    • pp.111-121
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    • 2009
  • Objectives : This study was performed to evaluate the efficacy of ampule containing herbal extract(Ulmus davidiana, Ginkgo biloba, Perilla ocymoides, Morus alba, Glycyrrhiza uralensis (licorice), and Angelica gigas) on skin wrinkles in adult women with facial wrinkles. Methods : A total of 12 women, 30 to 46 years of age, with wrinkles in the corner of eyes, applied ampule containing herbal extract twice daily for up to 12 weeks. Silicon replicas of right crow's feet area and antecubital fossa were taken before use of test product and at 4, 8 and 12 weeks. The replicas were analyzed by optical profilometry with Skin Visiometer SV600. The wrinkle and roughness parameters, R1, R2, R3, R4 and R5 were calculated and statistically analyzed. In addition, a subjective evaluation of product efficacy was conducted by patient's assessment. Results : The mean values of all the skin roughness parameters were decreased at 4-week, and decreased significantly at 8 and 12-week except R4 at 12-week after test product use. The subjective evaluation of wrinkle by patient's assessment was also improved. However, one patient noted stiffness of face after use of test product. Conclusions : These study suggested that the application of ampule containing herbal extract twice daily for 12 weeks may effectively improve the facial wrinkles without severe side effect.

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Skin friction measurements using He-Ne laser (He-Ne 레이저를 이용한 표면전단응력 측정에 관한 연구)

  • Choi, Seung-Ho;Lee, Yeol
    • Transactions of the Korean Society of Mechanical Engineers B
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    • v.21 no.7
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    • pp.939-947
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    • 1997
  • An experimental study of the skin friction measurement in a turbulent boundary-layer has been carried out. The skin friction measurements are made using the laser interferometer skin friction (LISF) meter, which optically detects the rate of thinning of an oil applied to the test surface. This technique produces reliable skin friction data over a wide range of flow situations up to 3-dimensional complicated flows with separation, where traditional skin friction measurement techniques are not applicable. The present measured data in a turbulent boundary-layer on a flat plate using the LISF technique shows a good comparison with the result from the previous velocity profile techniques, which proves the validity of the present technique. An extensive error analysis is carried out for the present technique yielding an uncertainty of about .+-.8%, which makes them suitable for CFD code validation purposes. Finally the measurements of the skin friction in a separated region after a surface-mounted obstacle are also presented.

A Study of Skin Resistance of Jeong-Acupuncture Points Using the Compound Electrode (복합전극을 이용한 정혈의 최대피부저항특성에 관한 연구)

  • 최진욱;최귀원;박영배
    • The Journal of Korean Medicine
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    • v.24 no.1
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    • pp.100-109
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    • 2003
  • Objectives : The purpose of this study is to 1. measure the skin resistance of jeong-acupuncture points using compound electrode, and 2. develop a database of skin resistance based on age and gender. Methods : The skin resistance of jeong-acupuncture points on the hands and feet of 191 healthy volunteers was measured using a specially designed compound electrode. A constant current of $5{\mu\textrm{A}}$ was applied to the measurement points and the skin resistance was obtained using amplifier, A/D converter and Acknowledge software program, Results : 1. ANOVA statistical analysis showed no significant differences between jeong-acupuncture points on hands and feet. 2. Paired samples t-test showed no significant differences between Yin-Yang meridian points, 3. When the data were sorted by gender, factor analysis showed statistically significant differences between male and female groups in all measured points except for left foot. 4. Based on the factor analysis, a significant relationship between the skin resistance and age was found in feet. However, no such relationship was found in hands. Conclusions : There are differences in skin resistance according to sex and age, Further clinical research is necessary using compound electrode method.

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Pear Skin Stain Caused by Mycosphaerella graminicola on Niitaka Pear (Pyrus pyrifolia Nakai)

  • Nam, Ki-Woong;Oh, Soh-Young;Yoon, Deok-Hoon
    • The Plant Pathology Journal
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    • v.30 no.3
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    • pp.229-235
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    • 2014
  • Pear skin stains on 'Niitaka' pears, which occur from the growing stage to the cold storage stage, reportedly negatively influence the marketing of pears. These stains on fruit skin are likely due to a pathogenic fungus that resides on the skin and is characterized by dark stains; however, the mycelium of this fungus does not penetrate into the sarcocarp and is only present on the cuticle layer of fruit skin. A pathogenic fungus was isolated from the skin lesions of infected fruits, and its pathogenicity was subsequently tested. According to the pathogenicity test, Mycosphaerella sp. was strongly pathogenic, while Penicillium spp. and Alternaria spp. showed modest pathogenicity. In this present study, we isolated the pathogenic fungus responsible for the symptoms of pears (i.e., dark brown-colored specks) and identified it as Mycosphaerella graminicola based on its morphological characteristics and the nucleotide sequence of the beta-tubulin gene. M. graminicola was pathogenic to the skin of 'Niitaka' pears, which are one of the most widely growing varieties of pears in South Korea.

Anti-Aging Effects of the Hanwoo Leg Bone, Foot and Tail Infusions (HLI, HFI and HTI) on Skin Fibroblast

  • Seol, Ja young;Yoon, Ji Young;Jeong, Hee Sun;Joo, Nami;Choi, Soon Young
    • Food Science of Animal Resources
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    • v.36 no.2
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    • pp.237-243
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    • 2016
  • Many researchers revealed that collagen contribute to maintaining the skin’s elasticity and inhibit wrinkling of skin. Korean native cattle (Hanwoo) bone (leg bone, foot and tail) infusion contains the various inorganic materials, collagen and chondroitin sulfate. All of this, a large quantity of collagen is included in Hanwoo infusion. Therefore, this study emphasized on the effects of collagen in the Hanwoo bone infusion. For the first time, Hanwoo bone infusions were directly added to the media of Human Dermal Fibroblast (NHDF-c) to test anti-aging effects. First, it was identified that growth rate of skin fibroblast was increased. Furthermore, the Hanwoo bone infusion increased a 50% of fibroblast collagen synthesis. Also, suppression of skin fibroblast aging was confirmed by treatment Hanwoo bone infusion. In conclusion, this study demonstrates the effects of infusion made from Hanwoo leg bone, foot and tail on anti-aging, wrinkle inhibiting and skin fibroblast elasticity maintaining. Therefore, this study identified that traditional infusion has effects that are good for skin elasticity.