• Title/Summary/Keyword: Skin Test

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Skin Pigment Recognition using Projective Hemoglobin- Melanin Coordinate Measurements

  • Yang, Liu;Lee, Suk-Hwan;Kwon, Seong-Geun;Song, Ha-Joo;Kwon, Ki-Ryong
    • Journal of Electrical Engineering and Technology
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    • v.11 no.6
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    • pp.1825-1838
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    • 2016
  • The detection of skin pigment is crucial in the diagnosis of skin diseases and in the evaluation of medical cosmetics and hairdressing. Accuracy in the detection is a basis for the prompt cure of skin diseases. This study presents a method to recognize and measure human skin pigment using Hemoglobin-Melanin (HM) coordinate. The proposed method extracts the skin area through a Gaussian skin-color model estimated from statistical analysis and decomposes the skin area into two pigments of hemoglobin and melanin using an Independent Component Analysis (ICA) algorithm. Then, we divide the two-dimensional (2D) HM coordinate into rectangular bins and compute the location histograms of hemoglobin and melanin for all the bins. We label the skin pigment of hemoglobin, melanin, and normal skin on all bins according to the Bayesian classifier. These bin-based HM projective histograms can quantify the skin pigment and compute the standard deviation on the total quantification of skin pigments surrounding normal skin. We tested our scheme using images taken under different illumination conditions. Several cosmetic coverings were used to test the performance of the proposed method. The experimental results show that the proposed method can detect skin pigments with more accuracy and evaluate cosmetic covering effects more effectively than conventional methods.

A Study on the Allergen Skin Test Prevalence in the Residents of a Non-Industrial Area (비산단지역 주민 피부 알레르기반응에 관한 연구)

  • Ahn, Seung-Chul;Kim, Dae-Seon;Yu, Hwa-Yon;Kwon, Young-Min;Zoo, Duck-Hyun
    • Journal of Environmental Health Sciences
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    • v.38 no.5
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    • pp.398-406
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    • 2012
  • Objectives: In order to investigate the relation between environmental pollution and its effect on human health in large-scale industrial complex regions, monitoring studies have been conducted since 2003. The main purpose of this Gangneung study is to produce background data which can be compared with several large-scale industrial complex regions such as Ulsan, Sihwa, Banwol, Gwangyang, Yeosu, Pohang and Cheongju Daesan industrial complexes. Methods: In this Gangneung study, 1,007 local residents were recruited and the framework of this study was designed to evaluate and monitor health effects associated with low-level but long-term exposure to environmental pollutants. A survey was performed based on personal questionnaires, medical check-ups, and allergy skin prick tests for twelve common allergens. The authors reviewed the prevalence rate of skin allergens in Gangneung compared with in large-scale industrial areas. The results are summarized as follows. Results: The diagnosis prevalence and medical treatment prevalence of asthma were lower than in industrial complex regions, but allergic rhinitis was higher. The allergy skin test prevalence was 26.0% and the most common allergens were dust mites (D. pteronysinus 16.7% and D. farinae 16.3%). Conclusions: The positive findings of the skin prick test were similar with large-scale industrial complex regions in Korea. Further study is required to find the cause of the regional differences in skin prick prevalence.

Human Skin Safety Test of Green Tea Cell Extracts in Condition of Allergic Contact Dermatitis

  • Kim, Hyun-Kyu;Choi, Sun-Young;Chang, Hui-Kyoung;Baek, Seok-Yun;Chung, Jin-Oh;Rha, Chan-Su;Kim, Beom-Joon;Kim, Myeung-Nam
    • Toxicological Research
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    • v.28 no.2
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    • pp.113-116
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    • 2012
  • Various kinds of positive effects of green tea extracts had been studied for long time which included anti-inflammation, anti-aging, and cardiometabolic effects. Although topical steroid and non-steroidal calcineurin inhibitors may control clinical symptoms of allergic contact dermatitis, some of patients also present allergic reaction to these topical agents. Therefore, we have tried green tea extracts for managing this skin disorder with expectation of anti-inflammatory effect without potential side effects including skin irritation and toxic responses. The toxicity test of green tea extract also did not show any sign of irritation in the skin throughout the test period. Moderate severity of allergic contact dermatitis presented satisfactory clinical outcome at second week follow-up which was final visit of outpatient. This result mean that green tea extract has a positive effect for managing allergic contact dermatitis but its potency and efficacy seem to be so not strong enough to control moderate severity allergy skin lesion. In this pilot study, we were able to conclude that green tea cell extracts might be applied for potential anti-inflammatory soaking without skin toxicity.

Customer satisfaction and skin care shop selection factors in the pandemic era impact on revisit intention (팬데믹 시대의 피부관리숍 선택요인이 고객만족도와 재방문 의도에 미치는 영향)

  • Byoung Ock Lee;Soo Nam Hong
    • Journal of the Korea Fashion and Costume Design Association
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    • v.25 no.2
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    • pp.83-95
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    • 2023
  • The purpose of this study was to identify the effect of skin care salons' decision factors on customer satisfaction and revisit intention during the COVID-19 pandemic. The subjects of this study were 220 women in their 20s to 50s who reside in Seoul and the Gyeonggi-do area and are users of skin care salons. The data was statistically analyzed using SPSS V.25.0 and detailed research results are as follows. For the analysis of this study, frequency analysis, factor analysis, reliability verification, independent sample T-Test, one-way analysis of variance, post hoc test, Duncan test, and regression analysis were conducted. First, as a result of examining whether skin care salon decision factors during the pandemic have a positive (+) effect on customer satisfaction, hygienic environment satisfaction and service environment satisfaction, which are sub-factors of customer satisfaction, had a significant effect on professionalism, kind service, and distance, which are sub-factors of decision factors, and are independent variables. Second, as a result of examining whether skin care salon decision factors during the pandemic have a positive (+) effect on revisit intention, decision factors, which are independent variables, including professionalism, kind service, price, and distance showed significant effects on human revisit intention, As for physical revisiting intention, only kind service, distance, and professionalism showed significant effects, while price did not have a significant effect. Third, as a result of examining whether customer satisfaction during the pandemic has a positive (+) effect on revisiting intention, the service environment satisfaction and hygienic environment satisfaction, which were sub-factors of independent variables, showed significant results for human and physical revisit intentions. In this study, service environment and hygienic environment satisfaction were important variables for skin care salon decision factors. Professionalism and kind service were important for human revisit intention. Therefore, overall service environment, hygiene, and safety should be prioritized to increase revisit intention and efforts must be made to retain and improve customer satisfaction

Effects of Dendrobii herba and Punica granatum Extract on the Anti-oxidant, Anti-inflammatory, Anti-wrinkle and Whitening (석곡(石斛), 석류(石榴)의 항산화, 항염증, 주름, 미백에 미치는 영향)

  • HwangBo, Min;Roh, Seok-Sun;Seo, Hyeong-Sik
    • The Journal of Korean Medicine Ophthalmology and Otolaryngology and Dermatology
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    • v.23 no.3
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    • pp.11-32
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    • 2010
  • Objective : The aim of this study is to determine the effects of Dendrobii herba extract and Punica granatum extract on skin disease and skin beauty. Methods : To investigate in vitro anti-oxidant activity assay, ethanol extracts of medicinal plants tested by DPPH radical, xanthine oxidase activity. In the next experiment, to investigate anti-inflammatory activity assay, examined by relations in NO synthesis, IL-$1{\beta}$, IL-6, TNF-${\alpha}$, NF-${\kappa}B$, COX-2, MAP kinase. To study Skin wrinkle formation effect, we were examined by tyrosinase activities, melanin synthesis in MNT-1 cell. Results : 1. In an anti-oxidant test, Dendrobii and Punica granatum extract showed high radical scavenging activity. 2. In an anti-inflammatory test, Dendrobii herba and Punica granatum extract weakly inhibited the lipopolysaccharide(LPS)-induced nitric oxide(NO) release from RAW 246.7 macrophage cells. Dendrobii herba and Punica granatum extract also inhibited LPS-induced IL-$1{\beta}$ and COX-2 expressions. The inhibitory effect of Dendrobii herba and Punica granatum extract on macrophage activation were via the inhibition of NF-${\kappa}B$, evidenced by transient transfection assay. however, Dendrobii herba and Punica granatum extract did not have any effects about activation of Jun-N-terminal kinase(JNK) and inhibition of p38 MAP kinase in RAW 264.7 cells. 3. In the skin wrinkle formation assay, Dendrobii herba and Punica granatum extract weakly inhibited collagenase and elastase, however it was not statistically significant. 4. In the skin whitening assay, Dendrobii herba and Punica granatum extract weakly inhibited tyrosinase activity, however, it was not statistically significant. They did not have any effect on melanin synthesis, indicating that they could not be applicable for skin whitening. Conclusion : Dendrobii herba extract and Punica granatum extract may play a significant role in skin disease and skin beauty.

Effects of Aloe and Violae herba Extract on the Anti-oxidant, Anti-inflammatory, Anti-wrinkle and Whitening (노회(蘆薈)(알로에), 자화지정(紫花地丁)의 항산화, 항염증, 주름, 미백에 미치는 영향)

  • Kim, Chang-Hun;Jung, Hyeon-A;Roh, Seok-Sun;Hong, Seok-Hoon
    • The Journal of Korean Medicine Ophthalmology and Otolaryngology and Dermatology
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    • v.23 no.1
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    • pp.23-43
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    • 2010
  • Objective : This study was performed to assess the effects of Aloe and Violae herba extracts on skin disease and skin beauty. Methods : Anti-oxidant effects were measured by the scavenging for DPPH radical, xanthine oxidase activity. Anti-inflammatory effects were examined by relations in NO synthesis, IL-$1{\beta}$, IL-6, TNF-$\alpha$, NF-kB, COX-2, MAP kinase. The skin wrinkle formation effects were measured by collagenase and elastase activities. The whitening effects were examined by tyrosinase activities, melanin synthesis in MNT-1 cell. Results : 1. In an anti-oxidant test, Aloe and Violae herba extracts showed high radical scavenging activity. 2. In an anti-inflammatory test, Aloe and Violae herba extracts strongly inhibited the lipopolysaccharide(LPS)-induced nitric oxide(NO) release from the RAW 246.7 macrophage cells. Aloe and Violae herba extracts also inhibited the LPS-induced IL-$1{\beta}$ and COX-2 expressions. The inhibitory effects of Aloe and Violae herba extracts on macrophage activation were via the inhibition of NF-kB, evidenced by transient transfection assay. Furthermore, Aloe and Violae herba extracts weakly inhibited the activation of Jun-N-terminal kinase(JNK) but they did not have any effects on p38 MAP kinase in RAW 264.7 cells. 3. In the skin wrinkle formation assay, Aloe extract strongly inhibited collagenase and elastase, whose activity are tightly related with the wrinkle formation. 4. In the skin whitening assay, Aloe and Viloae herba extracts weakly inhibited tyrosinase activity, however, it was not statistically significant. Besides they did not have any effects on melanin synthesis, indicating that they could not be applicable for skin whitening. Conclusion : This study show that Aloe and Violae herba extracts may play a significant role in skin disease and skin beauty.

Study of Skin Characteristics in Spring·Autumn and seasonal efficacy of Seosiokyongsan CP soap (봄 가을 피부특성 및 서시옥용산(西施玉容散) 저온숙성비누의 계절별 효능연구)

  • Choi, Sang Rak;Koo, Jin Suk
    • The Journal of Korean Medicine
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    • v.40 no.2
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    • pp.133-141
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    • 2019
  • Objectives: The condition of the skin is greatly influenced by seasonal changes. We wanted to know the seasonal change of skin condition and to find out the difference in the efficacy of Seoshiokyongsan (SSOOS) CP soap in spring and autumn. We are to help people who use soap to make a wise choice in choosing a cleanser according to the season. Methods: To investigate the seasonal skin condition, this experiment was conducted to examine the skin condition of spring and autumn in 20 students at A university. To compare the seasonal efficacy of Seosiokyongsan (SSOOS) CP soap, we had skin test 10 students in spring and autumn. We made herbal fermented soaps using SSOOS and distributed them to experiment participants. We let them wash their face in the morning and evening for 6 weeks using herbal fermented soap. Prior to the experiment, their skin condition was checked and assessed using A-ONE Smart One-Click Automatic Facial Diagnosis System three times at 3-week intervals. After the experiment, the changes of skin were measured and analyzed through facial analysis test. Results: In spring and autumn, the oil of T zone and U zone was significantly less and the water content was significantly higher in autumn than in spring. In the case of using the SSOOS CP soap, water content increased and oil content decreased in spring, oil content and elasticity increased in autumn. Conclusion: There is a difference in the skin condition according to the season and SSOOS CP soap showed difference in efficacy in spring and autumn. So we should pay attention to seasonal soap selection.

Cosmeceutical Properties of Fructan (Levan) Produced by Zymomonas mobilis

  • Kim, K. H.;C. S. Han;K. I. Ko;E. K. Yang;Kim, C. H.;Park, S. N.
    • Proceedings of the SCSK Conference
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    • 2003.09a
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    • pp.700-718
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    • 2003
  • Fructan, a polysaccharide existing in plants or produced by microorganisms, is a sugar polymer of fructose with $\beta$-2,6 linkages. In this study, we investigated some cosmeceutical properties of Fructan such as moisturizing effect, cell proliferation effect, anti-inflammation effect and cell cytotoxicity. Zymomonas mobilis, a microorganism producing Fructan, was cultured in a medium containing 10% sucrose and 2% yeast extract as main components for 24 hours at 37$^{\circ}C$ and pH 7. Fructan was obtained by precipitation from the cultured medium by adding alcohol (alcohol ratio of 1:3) after removing the enzyme by centrifuging. Fructan exhibited almost same moisturizing effect as hyaluronic acid and cell proliferation effect on human fibroblast and keratinocyte as well. Moreover, on cell proliferation test on bio-artificial skin constructed by 3-dimensional(3-D) culture after inducing primary skin inflammation with 0.5% sodium lauryl sulfate (SLS), the 3-D artificial skin treated with 0.01 mg/ml, 0.05mg/ml of Fructan exhibited higher cell proliferation than the 3-D artificial skin treated with SLS only. On anti-inflammation test on 3-D artificial skin evaluated by measuring secreted quantity of interleukin-1$\alpha$ (IL-1$\alpha$) which is a pre-inflammatory mediator induced by SLS, the quantity of IL-1$\alpha$on the 3-D artificial skin treated with 0.01 mg/ml, 0.05mg/ml of Fructan was less than the one on the 3-D artificial skin treated with SLS only. As a result of these studies, Fructan has anti-inflammation effect against inflammatory reaction by a skin irritant as well as cell proliferation effect in bio-artificial skin. Fructan was also evaluated as a safe material without any toxicity in safety tests using fibroblasts and animals.

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The Correlation Analysis of Fluid Intake, Skin Hydration and Skin pH of College Students (대학생의 수분섭취, 피부 수분보유도 및 피부 pH와의 관계)

  • Kim, Nam-Jo;Hong, Hae Sook
    • Journal of Korean Biological Nursing Science
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    • v.17 no.2
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    • pp.132-139
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    • 2015
  • Purpose: The purpose of this study was to verify the correlation analysis between fluid intake on skin hydration and pH of college students. Methods: The subjects were 129 female nursing students in D city. Data were collected by a self-administered questionnaire, using a skin moisture checker and skin pH meter on faces, hands, and feet. The collected data were analyzed by descriptive statistics, t-test, ANOVA, and Pearson correlation analysis, using SPSS WIN, 20. Results: The daily fluid intake was composed of 57% pure water, 21% caffeinated beverages, 22% non-caffeinated beverages. There were significant differences in average skin hydration on the three body parts according to pure water, caffeinated beverages, and non-caffeinated beverages; however, there was no significant difference measured by fluid intake. There was a significant positive correlation between fluid intake and skin hydration: between pure water and skin hydration. There was significant negative correlation between caffeinated beverages and skin hydration: between non-caffeinated beverages and skin hydration. Conclusion: The results suggest that fluid intake, pure water, caffeinated beverages, and non-caffeinated beverages have an effect on skin hydration and pH. Therefore, it is good to increase the amount of fluid intake but, it is recommended to increase the amount of intake of pure water rather than beverages to improve skin status.

Compressive Behavior for Smart Skin of Sandwich Structure (스마트 스킨 샌드위치 시편의 압축거동 연구)

  • Kim, Young-Sung;Kim, Yong-Bum;Park, Hoon-Cheol;Yoon, Kwang-Joon;Lee, Jeo-Hwa
    • Journal of the Korean Society for Aeronautical & Space Sciences
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    • v.30 no.8
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    • pp.56-64
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    • 2002
  • In this work, a smart skin of multi-layer structure is designed and manufactured. Through the compression test, the characteristic of smart skin behavior was examined. We have predicted stress of each layer and the first failed layer of the smart skin structure by using MSC/NASTRAN. The finite element model was verified by comparing measured data from the compression test and result from the geometrically linear/non-linear analysis. The finite element model was used for obtaining design data from the parametric study. It was confirmed that shear moduli of honeycomb core affect the buckling load of smart skin where shear deformation was considerable.