• 한방안이비인후피부과학회지
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• 제13권1호
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• pp.237-252
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• 2000

Pressure sore is an area of ulceration and necrosis of the skin and underlying tissues usually occuring over the bony prominences of the body after prolonged or often repeated pressure. We reviewed and summarized the published articles and treatise on the treatment of pressure sore. The results were as follows : 1. Pressure sore occur due to prolonged or often repeated pressure. So it is better than decubitus ulcer that is called pressure sore. 2. The most common lesions of pressure sore are sacrum, ischial tuberosity, greater trochanter. 3. The cause of pressure sore are change of comprehension. urine, moisture, change of the ability of activity and exercise, shearing force. 4. The elements to influence on wound healing are collagen accumulation velocity, nutrition condition, Vitamine C, copper, iron. oxygen pressure, steroids, cell-toxic drug, radiation. 5. Non-operative treatments are managements of skin such as avoiding consistant pressure, dressing, preventing moisture, understanding patient and protecter, preventing spasm, improvement of systemic nutrition condition. 6. Operative treatements are debridement, suture, skin transplantation, muscle flap and musculaocutaneous flap surgery. Recently V-${\Gammer}$ advancement surgery in use of muscle and musculocutaneous flap is generally maded. 7. Complications of post-operation are wound rupture, infection, disappearance of transmitted skin, necrosis of flaps.

• Journal of Acupuncture Research
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• 제29권4호
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• pp.7-18
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• 2012

Objectives : The purpose of this study is to evaluate the effects of Miso facial acupuncture on facial reduction and improvement of skin condition. Methods : From March to May 2012, 20 women in their twenties to forties with no facial diseases were recruited. Miso facial acupuncture was performed on the both side of their face twice a week, total seven times. The 3D face photographs of each participant were checked 5 times ; before treatment, after 1st treatment, 4th treatment, 7th treatment and 10 days from the last treatment using RS-400FL(Morpheus Co. Korea) and REAL FACE. The surface distances of the 4 lines on the face were measured using Renai MEF program. The improvement of skin condition was evaluated by water content, trans epidermal water loss(TEWL), erythema index and melanin index using MPA 5. They were checked 4 times ; before treatment, 4th treatment, 7th treatment and after 10 days from the last treatment. We analyzed data using Paired t-test(p<0.05) and Wilcoxon signed rank test(p<0.05). Results : One case was dropped out due to pain and edema after 4th treatment. The surface distances of the 4 lines on face were significantly reduced and maintained after 10 days from last treatment. Water content was significantly increased and maintained after 10 days from last treatment. TEWL was significantly decreased. Erythema index was significantly decreased from the 3rd evaluations. Melanin index was slight decreased with no significance at the 2nd evaluations. Conclusions : These results show that Miso facial acupuncture can reduce sizes of the face and improve skin condition such as water content, TEWL and erythema index except melanin index.

• 대한한방소아과학회지
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• 제35권1호
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• pp.40-47
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• 2021

Objectives The purpose of this study is to confirm the effect of alleviating inflammation through creating skin fat barrier from Scutellaria baicalensis extract. Methods Four-week-old Balb/C mice were divided into four groups: control group (Ctrl), lipid barrier eliminated group (LBEG), dexamethasone (DM) treated group after lipid barrier elimination (DMTG), and Scutellaria baicalensis (SB) treated group after lipid barrier elimination (SBTG). Scutellaria baicalensis extract were administered for 5 days after removal of the fat barrier. Changes in skin condition, improvement of the fat barrier, and relief of inflammation were observed in each group. Results Compared to LBEG and DMTG, pathological skin damage and tissue changes were less in SBTG, and transepidermal water loss (TEWL) and pH were also significantly reduced. Filaggrin was also significantly increased in SBTG. KLK7, PAR-2, and TSLP in SBTG also showed significant reduction compared to the LBEG and DMTG. Conclusions Scutellaria baicalensis extract restores skin barrier and relieves inflammation through the creation of skin fat barrier. This means that the Scutellaria baicalensis extract can regulate Th2 differentiation through the creation of the epithelial fat barrier.

• 문화기술의 융합
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• 제3권3호
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• pp.37-42
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• 2017

본 연구는 피부의 각질층에 분포되어 있는 유지질의 변화 상태를 조절하는 구조체계에 대해 고안한다. 피부구조에 유지질 성분이 어떻게 진행되는지 형태학으로 구성하였고, 주어진 세포사이와 세포횡단의 조건으로 기계적으로 조절되는 형태를 구성하였으며, 구조적인 기능으로 조절기능의 변화 상태를 확인하였다. 유지질 성분에서 피부의 모형을 구성하여 각층에 따른 유기질 상태의 피부 임피던스를 피부의 측정 임피던스 시스템으로 구성하여 진행하였다. 측정 임피던스는 ${\lambda}-Lip-RSC$, ${\lambda}-Lip-RSL$, ${\lambda}-Lip-CSG$, ${\lambda}-Lip-CSS$ 와 ${\lambda}-Lip-RSB$로 형성하였고, 세포사이와 세포횡단의 조건으로 변화의 차가 있고, 변환을 제어하는 전달시스템을 구성과 변환모델을 세분화하여 구축하였다. 앞으로 유지질 상태에서 피부의 기능적 효능조절이 가능한 유지질 성분의 조절시스템을 구성하여 지속적인 피부의 개선효과가 진행 될 것으로 예상된다.

• Journal of Ginseng Research
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• 제35권2호
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• pp.149-154
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• 2011

In order to determine the efficacy of functional foods, objective measurement of the severity of atopic dermatitis (AD) after taking foods is important. The aim of this study was to conduct an objective evaluation of whether Korean red ginseng (KRG) might be helpful for improvement of skin condition and serum IgE in patients with AD. Thirty atopic patients (18 females and 12 males) participated in this study. Patients took KRG for 16 weeks. Bioengineering methods, including the corneometer and evaporimeter, were used at the start of the study and after 8 weeks and 16 weeks. In addition, we assessed serum IgE levels and the severity scoring of the atopic dermatitis (SCORAD) index. Transepidermal water loss and skin hydration showed significant improvement after 16 weeks. A significant decrease in the SCORAD index, as well as in serum IgE level, was observed after 16 weeks. Our results demonstrated that KRG may be helpful as a functional food for patients with AD.

• 한국응용과학기술학회지
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• 제41권1호
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• pp.69-82
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• 2024

본 연구의 목적은 640 nm LED 조사와 아로마테라피가 목 피부 상태에 미치는 영향을 체계적으로 평가하고 비교하는 것이다. 20명의 여성 참여자를 대상으로 A그룹(640 nm LED 조사 + 아로마테라피)와 B그룹(640 nm LED 조사만)으로 나뉘어, 주 2회씩, 총 8회의 실험을 진행하였다. 실험 결과, 수분 함량은 A그룹(p<0.01)과 B그룹(p<0.001) 모두 유의하게 나타났으며, 주름 지수는 A그룹(p<0.01)과 B그룹(p<0.05) 모두 유의하게 나타났다. 또한, 치밀도 변화는 A그룹(p<0.001)과 B그룹(p<0.05) 모두 유의하게 나타났으며, 탄력 변화는 A그룹(p<0.001)과 B그룹(p<0.001) 모두 유의하게 나타났다. 피부색 변화는 A그룹에서는 (p>0.05) 유의하지 않았고, B그룹에서는 (p<0.05) 유의하게 나타났다. 기미 및 색소 침착 변화는 A그룹에서 (p<0.05) 유의하게 나타났으며, B그룹에서는 (p>0.05) 유의하지 않았다. 이러한 결과는 아로마테라피와 640 nm LED 조사를 병행하는 것이 목 피부 상태를 향상시키는 데 높은 효과를 나타낼 수 있음을 시사한다.

• 대한화장품학회지
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• 제47권1호
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• pp.65-73
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• 2021

피부 염증은 흉터, 노화 뿐만 아니라 아토피와 같은 질환으로 발전할 수 있어 이를 조절하는 것이 매우 중요하다. 본 연구에서는 최근 인체에서 염증을 조절하는 것으로 알려진 specialized pro-resolving mediators (SPMs)의 in vitro 합성과 화장품 적용 가능성을 확인하였다. 대두의 lipoxygenase를 이용하여 mono 또는 di-hydroxy docosahexaenoic acid가 혼합된 시료 S-SPMs를 제작하였고 효능 평가에 이용하였다. 먼저, UVB로 염증을 유도한 세포에서 TNF-α와 IL-6의 발현이 S-SPMs에 의해 감소하고, 미세먼지에 의해 유도된 nitric oxide (NO)의 생성 역시 감소하는 것을 확인하여 S-SPMs의 항염 효능을 확인하였다. 또한, S-SPMs을 처리한 조건에서 malondialdehyde (MDA) 생성이 감소하여 지질 과산화 억제능이 있음을 확인하였고 S-SPMs에 의한 matrix metalloproteinase-1 (MMP-1)의 발현 감소, procollagen type I의 함량 증가를 통해 collagen 분해를 억제하고 반대로 합성은 촉진함을 확인하였다. 끝으로 filaggrin과 loricrin의 발현이 S-SPMs에 의해 증가한 것을 확인하여 피부 장벽 강화 효능을 확인하였다. 위 결과를 토대로 S-SPMs은 피부의 염증 억제와 함께 손상회복, 주름개선 및 장벽 강화를 위한 소재로 활용 가능함을 확인하였다.

• 복식문화연구
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• 제14권6호
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• pp.1056-1068
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• 2006

The purpose of this study is to examine the changes and the using condition of functional cosmetics through articles of newspaper and the survey on functional cosmetics. The data analysis examined newspaper articles that demonstrate a grasp of the general trends of cosmetics, and these articles were chosen from the "Cosmetics Newspapers" and the "Jangeop Newspaper" with content primarily emphasizing articles about cosmetics. All articles on functional cosmetics were collected for the period from 2000 to 2005, and excluding repeated articles a total of 703 cases were examined. In addition, a survey was performed to examine how much women are using functional cosmetics and what the current state of their use is. This survey was conducted from October $1{\sim}20$, 2004, and respondents consisted of 350 adult females living in the areas of Daejeon, North and South Chungcheong Provinces and Daegu. Responses from a total of 302 individuals were included in the data analysis. The results of this study show a situation where the current use of functional cosmetics is gradually increasing, and because of external changes in the skin resulting from the development of modern society, functional cosmetics are being used by women as a means of increasing their opportunities for personal expression due to their skin improvement effects as well as increased confidence and a sense of satisfaction.

• 대한화장품학회:학술대회논문집
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• 대한화장품학회 2003년도 IFSCC Conference Proceeding Book II
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• pp.149-162
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• 2003

Moisturizing the skin is one of the most important functions of skincare cosmetics, because water plays a significant role in keeping the skin healthy. There are various humectants including polyol (glycerin and 1,3-butylene glycol), water-soluble polymers, and botanical extracts. It is well known that the increased amount of polyol in lotion for obtaining high moisturizing effect gives a sticky feeling to the skin. Therefore, a few humectants that can give high moisturizing effect without a sticky feeling for lotion formula is available. On the other hand, oil-based lipstick is well known to have a difficulty to contain a large amount of hydrophilic humectants, because the humectants is unable to be mixed well into oil-based lipsticks and give the lips a peculiar taste. There are newly developed humectants, polyoxyethylene/polyoxypropylene dimethyl ether (EPDME) that can solve these problems describable above. EPDME is a random copolymer of ethylene oxide and propylene oxide. EPDME gives a low sticky feeling with a high moisturizing effect when it is used in lotion. As a remarkable character, EPDME can show not only a preventing effect on rough and dry skin, but also a improving effect upon the use for 1-4 weeks. EPDME can show a synergistic effect with glycerin on preventing to rough and dry skin. Since EPDME can be dissolved in oil-based formulation and used as an ingredient of lipsticks, EPDME can give a moisturizing effect that allows lip to be healthy condition. EPDME can also give no peculiar taste even upon the use of a large amount. EPDME is a useful cosmetic ingredient that can show a good skin care effect in both water-based formula and oil-based formula. EPDME of which polarity can be controllable is expected to be used for various cosmetic applications in near future.

• 대한화장품학회:학술대회논문집
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• 대한화장품학회 2003년도 IFSCC Conference Proceeding Book II
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• pp.253-267
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• 2003

Inositol and phytic acic extracted from rice bran were investigated for applying cosmetics. Skin lotions containing 0∼3.0wt% inositol and 0∼1.5wt% phytic acid were applied respectively, to the arm skins of 45 Asian women 20'-40's for 7 weeks. Improvement on moisture was evaluated. In addition, improvements on sebum, elasticity, and wrinkle were examined after applying placebo, Inositol and phytic acid-containing skin lotions for face, respectively. For 1.0 wt% inositol resulted in 19% increase of moisture. The wrinkle reduction and elasticity improved 12.4% and 17.0% on average, respectively. Applying 0.5wt% phytic acid resulted in 71.6% increase the moisture. Improvements on wrinkle and elasticity were 15.9% and 21.9% respectively. Applying inositol or phytic acid regardless of dry or oily, resulted in sebum value recovery to that of the normal skin after 2- 4 weeks. Inositol is inferior to phytic acid in improvenients of the skin, and phytic acid is not suitable to sensitive skin. So 0-0.5wt% of phytic acid were added to 1.0wt% inositol and similar experiments were carried out. In case of added 0.1wt% phytic acid, moisture increased 63.8% approximately. Improvements on elasticity and reduction on wrinkle were 17.2% and 17.4%, respectively. Both skin types were turned to normal skin type after 2 weeks. It could improve the skin condition when used inositol added phytic acid. The optimized concentration of phytic acid was 0.10wt% with 1.0wt% of inositol for synergic effect.