• Transactions of the Korean hydrogen and new energy society
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• v.31 no.4
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• pp.395-403
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• 2020

In this paper, the performance characteristics of the impeller and volute in the 2 vane pump were investigated using response surface method (RSM) with commercial computation fluid dynamics (CFD) code. Design variables were defined with the impeller blade angle and volute area distribution. The objective functions were defined as the total head, total efficiency and solid material size of the 2 vane pump. The design optimization of the design variables was determined using the RSM. The numerical results for the reference and optimum models were compared and discussed in this work.

• Journal of Microbiology and Biotechnology
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• v.19 no.12
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• pp.1620-1627
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• 2009

The design and expression of an antihypertensive peptide multimer (AHPM), a common precursor of 11 kinds of antihypertensive peptides (AHPs) tandemly linked up according to the restriction sites of gastrointestinal proteases, were explored. The DNA fragment encoding the AHPM was chemically synthesized and cloned into expression vector pGEX-3X. After an optimum induction with IPTG, the recombinant AHPM fused with glutathione S-transferase (GST-AHPM) was expressed mostly as inclusion body in Escherichia coli BL21 and reached the maximal production, 35% of total intracellular protein. The inclusion body was washed, dissolved, and purified by cation-exchange chromatography under denaturing conditions, followed by refolding together with size-exclusion chromatography and gradual dialysis. The resulting yield of the soluble GSTAHPM (34 kDa) with a purity of 95% reached 399 mg/l culture. The release of high active fragments from the AHPM was confirmed by the simulated gastrointestinal digestion. The results suggest that the design strategy and production method of the AHPM will be useful to obtain a large quantity of recombinant AHPs at a low cost.

• Proceedings of the Korean Society for Agricultural Machinery Conference
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• 1993.10a
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• pp.1222-1229
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• 1993

An advanced design environment , which is based on adaptive and knowledge -based finite elements (INTELMESH), has been developed. Unlike other approaches, INTEMMESH incorporates the information about the object geometry as well as the boundary and loading conditions to generate an ${\alpha}$-priori finite element mesh which is more refined around the critical regions of the problem domain. INTEMMESH is designed for planar domains and axisymmetric 3-D structures of elasticity and heat transfer subjected to mechanical and thermal loading . It intelligently identifies the critical regions/points in the problem domain and utilize the new concepts of substructuring and wave propagation to choose the proper mesh size for them. INTEMMESH generates well-shaped triangular elements by applying trangulartion and Laplacian smoothing procedures. The adaptive analysis involves the intial finite elements analyze and an efficient ${\alpha}$-posteriori error analysis involves the initial finite element anal sis and an efficient ${\alpha}$-posteriori error analysis and estimation . Once a problem is defined , the system automatically builds a finite element model and analyzes the problem though automatic iterative process until the error reaches a desired level. It has been shown that the proposed approach which initiates the process with an ${\alpha}$-priori, and near optimum mesh of the object , converges to the desired accuracy in less time and at less cost. Such an advanced design/analysis environment will provide the capability for rapid product development and reducing the design cycle time and cost.

• Computational Structural Engineering
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• v.8 no.2
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• pp.123-132
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• 1995

Genetic Algorithms(GA), which are based on the theory of natural evolution, have been evaluated highly for their robust performances. Traditional GA has mostly used binary code for representing design variable. The binary code GA has many difficulties to solve optimization problems with continuous design variables because of its large computer core memory size, inefficiency of its computing time, and its bad performance on local search. In this paper, a real code GA is proposed for dealing with the above problems. So, new crossover and mutation processes of GA are developed to use continuous design variables directly. The results of read code GA are compared with those of binary code GA for several single and multiple objective optimization problems. As a result of comparisons, it is found that the performance of the real code GA is better than that of the binary code GA, and concluded that the real code GA developed here can be used for the general optimization problem.

• Journal of Korean Society of Water and Wastewater
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• v.29 no.6
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• pp.659-666
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• 2015

In this study, Hazen-Williams C value of pipes in wide waterworks system was estimated and statistically analyzed. Hazen-Williams C value of water pipe was predicted after 20 years of service period. From the results, it was found that C value of water pipe for treated water maintained higher value of 110 after 20 years of installation. Furthermore, it was found that velocity coefficients of steel pipe for less than and more than 20 years of installation were 117.7 and 109.3, respectively. C value of ductile iron pipe for less than and more than 20 years of installation were 118.1 and 114.2, respectively. In this study, it was also found that small value of C is used in the design of water pipe system. Therefore, excessively bigger size of pipe can be determined in the design of water pipe system. From the results of present study, optimum value of C can be used to avoid the oversized design of water pipe system.

• Tunnel and Underground Space
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• v.28 no.2
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• pp.125-141
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• 2018

For a long-term mine development plan, the determination and design of mine tunnel size are very important because it is the basis of plans for equipment, transportation and operation. The ${\bigcirc}{\bigcirc}$ mine has had a difficulty in changing the mining plan due to the design of the tunnels with an emphasis on productivity improvement, and much effort was needed to maintain the mine tunnel. In this study, we designed the mine tunnel with optimized tunnel span considering the mechanical properties of rockmass and established the support plan. To do this, the estimation of the mechanical parameters(Swelling pressure, deformation coefficient and earth coefficient), field investigations and various analyses were carried out. As a result, it was necessary to consider the downsizing of the tunnel section in order to maintain the tunnel stability and dimension by using the roof bolt and analyzed that various functional constructions of the support material and method would be required to maintain the current tunnel size.

• Transactions of the Korean Society of Mechanical Engineers A
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• v.37 no.10
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• pp.1279-1289
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• 2013

In recent times, turbomolecular pumps (TMPs) have been used frequently to generate and maintain high and clean vacuum. Because of the high-speed rotation of the rotor, its structural safety should be treated as the first design concern. This paper presents the structural analysis and optimization of rotor blades of a TMP. To increase the numerical efficiency in the finite element modeling and analysis, the P-method provided in Pro/ENGINEER was used for simulation. The structural responses for several types of rotor blades were investigated, and the effects of the blade angle, blade length, and round size are thoroughly studied for each type of TMP blade. In addition, structural optimization to reduce and even the maximum stress at each stage of the TMP by changing the size of rounds between the blade and the hub was performed very successfully by using the P-method.

• International Journal of CAD/CAM
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• v.4 no.1
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• pp.33-45
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• 2004

In this work, a rational procedure has been formulated for the selection of points approximating slice contours cut in LOM (Laminated Object manufacturing) with first order approximation. It is suggested that the number of points representing a slice contour can be 'minimised' or 'optmised' by equating the horizontal chordal deviation (HCD) to the user-defined surface form tolerance. It has been shown that such optimization leads to substantial reduction in slice height calculations and NC codes file size for cutting out the slices. Due to optimization, the number of contour points varies from layer to layer, so that points on successive layer contours have to be matched by four sided ruled surface patches and triangular patches. The technological problems associated with the cutting out of triangular patches have been addressed. A robust algorithm has been developed for the determination of slice height for optimum and arbitrary numbers of contour points with different strategies for error calculations. It has been shown that optimisation may even lead to detection and appropriate representation of elusive surface features. An index of optimisation has been defined and calculations of the same have been tabulated.

• Journal of Welding and Joining
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• v.17 no.6
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• pp.53-61
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• 1999

The use of thick plate in increasing in recent years due to the rapid expansion of chemical plants, nuclear plants, ships and other industrial plants. Welding is the most popular joining techniques employed in manufacturing industrial machineries and structures. Normally, Groove shapes are prepared according to appropriate rules and regulations such as KS, JIS, AWS, LR, DNV and etc. for various thicknesses of plate. However those groove angles tend to be too large. As a result of large groove angle, residual stress, deformation of material and strength reduction is obtained. Therefore, the reliability and safety of structures and machinery tend to be decreasing. Therefore, in this paper, theoretical as well as experimental study are carried out to find optimum groove shapes for T-welded joint of mild steel. The test specimen are made in same condition with simulation model. Welding residual stresses measurement by sectional cutting method. ⅰ) The mechanical difference for change the thickness of plate and groove angle are not appeared. ⅱ) In a mechanical point of view minimum preparation angle(40°) is more suitable than maximum groove angle(60℃). ⅲ) The measurement value and distribution of welding residual stresses are not effected largely by groove angle. It is mechanical restraint that mainly affect welding residual stresses distribution. In mechanical point of view minimum groove angle is more suitable than maximum groove angle. Therefore, it is appropriate to minimize the size of groove shape in strength and safety.

• Journal of the Korean Institute of Telematics and Electronics T
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• v.35T no.1
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• pp.75-81
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• 1998

This paper is to optimize single-element piezoresistor shear stress strain gauge related to aspect ratio of rectangular diaphragm. The shear stress distribution on diaphragm has been simulated by finite-element method(FEM). As simulation results, the maximum sensitivity for strain gauge was appeared at the center of diaphragm with aspect ratio 3, and in along to long edge with the ratio 2. The diaphragm with ratio 2 is not acceptable due to the yield of mask alignment in IC process technology. The optimum condition of diaphragm with respect to good sensitivity was realized in the case of ratio 3. In this case, the area by gauge was 8% of overall size of rectangular diaphragm.