• Asian Pacific Journal of Cancer Prevention
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• 제15권20호
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• pp.8685-8688
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• 2014

The objective of the present study was to investigate cloning, expression, and functions of the recombinant protein, Siva1. Siva1 gene was synthesized by RT-PCR from HCT116 cells. Plasmids were cleaved with the restriction endonuclease, BamH1/Sal1 and products were connected to pQE30, which underwent cleavage by BamH1/Sal1. The recombinant plasmid, pQE30-Siva1, was identified after digestion with restriction endonucleases followed by transformation into E. coli M15. Expression of Siva1 was induced by IPTG and identified by SDS-PAGE following purification with affinity chromatography. The results showed that size of Siva1 was 12 kDa, consistent with the molecular weight of the His-Siva1 fusion protein. Functional test demonstrated that Siva1 significantly inhibited the invasion and migration of HCT116 cells. It may thus find clinical application for control of cancers.

• Bulletin of the Korean Chemical Society
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• 제33권8호
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• pp.2789-2792
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• 2012

• 한국미생물·생명공학회지
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• 제45권3호
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• pp.200-208
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• 2017

Actinobacteria are prolific producers of a large number of natural products with diverse biological activities. In the present study, an actinobacterium isolated from sunflower rhizosphere soil sample collected from Medak, Andhra Pradesh, South India was identified as Amycolatopsis thermoflava strain SFMA-103. A pigmented secondary metabolite in culture broth was extracted by using methanol and it was further purified by silica gel column chromatography with methanol-chloroform solvent system. Structural elucidation studies based on UV-visible, 1D and 2D-NMR, FT-IR, and mass spectroscopic analyses confirmed the structure as 1-methoxy-3-methyl-8-hydroxy-anthraquinone. It showed significant in vitro anticancer activity against lung cancer and lymphoblastic leukemia cells with $IC_{50}$ values of 10.3 and $16.98{\mu}M$, respectively. In addition, 1-methoxy-3-methyl-8-hydroxy-anthraquinone showed good free radical scavenging activity by DPPH method with an $EC_{50}$ of $18.2{\mu}g/ml$. It also showed other promising superoxide radical scavenging, nitric oxide radical scavenging and inhibition of lipid peroxidation activities. This is a first report of anti-proliferative and antioxidant activities of 1-methoxy-3-methyl-8-hydroxy-anthraquinone isolated from A. thermoflava strain SFMA-103 which may find potential application in biotechnological and pharmaceutical fields.

• Journal of applied mathematics & informatics
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• 제42권1호
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• pp.207-212
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• 2024

In this paper, we study Malcev algebra bundles and Malcev algebra bundles of finite type. Lie algebra bundles and Lie transformation algebra bundles are defined using given Malcev algebra bundle and we conclude some results for finite type.

• International Journal of Concrete Structures and Materials
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• 제4권1호
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• pp.55-62
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• 2010

The performance evaluation of a sodium lauryl sulfate to qualify as a foaming agent is presented in this paper. When new surfactants are used a systematic study of production parameters on the foam characteristics needs to be undertaken unlike proprietary foaming agents and foam generator for which manufacturer has predefined the parameters. The relative influence of the foam parameters and optimization of factors were carried out through a systematic experiment design. The foam production parameters namely foam generation pressure and dilution ratio of foaming agents are observed to have significant effect on all foam characteristics with the exception of foam output rate on which only foam generation pressure has influence. The foam with good initial foam density need not necessarily be stable foam. The optimum levels of foam production parameters are determined for the surfactant Sodium lauryl sulfate which can be used to produce stable foam for foam concrete production.

• Kyungpook Mathematical Journal
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• 제54권4호
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• pp.595-606
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• 2014

In this paper three more right Jacobson-type radicals, $J^r_{g{\nu}}$, are introduced for near-rings which generalize the Jacobson radical of rings, ${\nu}{\in}\{0,1,2\}$. It is proved that $J^r_{g{\nu}}$ is a special radical in the class of all near-rings. Unlike the known right Jacobson semisimple near-rings, a $J^r_{g{\nu}}$-semisimple near-ring R with DCC on right ideals is a direct sum of minimal right ideals which are right R-groups of type-$g_{\nu}$, ${\nu}{\in}\{0,1,2\}$. Moreover, a finite right $g_2$-primitive near-ring R with eRe a non-ring is a near-ring of matrices over a near-field (which is isomorphic to eRe), where e is a right $g_2$-primitive idempotent in R.

• International Journal of Computer Science & Network Security
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• 제21권7호
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• pp.1-7
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• 2021

An amazing growth in the field of Internet of Things (IoT) and Blockchain based smart cities from both industry and academia has been witnessed in the recent years. There are many smart applications such as intelligent transportation, smart banking, improving the life style of citizen, energy consumption and managing the waste in the city, handling home needs are supporting the Smart city concept. These applications are profoundly supported by the advanced technologies like Blockchain as well as IoT in the recent past. Smart cities can be supported by the Blockchain core concepts such as secure, transparent, decentralized and immutable nature. Still, Blockchain and IoT technologies implementation in smart cities are in their early stages and significant research efforts are desirable to integrate them. This review article explores the roles and responsibilities of Blockchain and IoT in building smart cities.

• Journal of applied mathematics & informatics
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• 제22권1_2호
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• pp.67-82
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• 2006

In this paper, we present a finite difference method for the implementation of the rotation of a circular cylinder in the incompressible flow field by solving the two-dimensional unsteady Navier-Stokes equations. The approach is to use staggered grid method so that the accuracy and order of convergence of the associated algorithms can be maintained. The proposed method is easy to be implemented and is effective. A set of simulations for the flow dynamics is provided to show the computational results.

• International Journal of Computer Science & Network Security
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• 제23권11호
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• pp.73-76
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• 2023

We introduce DCNN and DRAE appraoches for compression of medical videos, in order to decrease file size and storage requirements, there is an increasing need for medical video compression nowadays. Using a lossy compression technique, a higher compression ratio can be attained, but information will be lost and possible diagnostic mistakes may follow. The requirement to store medical video in lossless format results from this. The aim of utilizing a lossless compression tool is to maximize compression because the traditional lossless compression technique yields a poor compression ratio. The temporal and spatial redundancy seen in video sequences can be successfully utilized by the proposed DCNN and DRAE encoding. This paper describes the lossless encoding mode and shows how a compression ratio greater than 2 (2:1) can be achieved.

• Journal of information and communication convergence engineering
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• 제17권1호
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• pp.84-90
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• 2019

Applications of unmanned aerial vehicles (UAVs) in the military environment have become popular because they require minimum human contribution and can avoid accidents during missions. UAVs are employed in various missions such as reconnaissance, observation, aggression, and protection. Consequently, counter-measures, known as anti-drone technologies, have been developed as well. In order to protect against threats from anti-drone technologies and enhance the survivability of UAVs, this study proposes an evasive measure. The proposed bio-inspired evasive maneuver of a UAV mimics a dragonfly's irregular flight. The unpredictable UAV movement is able to confuse enemies and avoid threats, thereby enhancing the UAV's survivability. The proposed system has been implemented on a commercial UAV platform (AR Drone 2.0) and tested in a real environment. The experiment results demonstrate that the proposed flight pattern has larger displacement values compared to a regular flight maneuver, thus making the UAV's position is difficult to predict.