• Title/Summary/Keyword: Site-Specific Performance

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Determination of Optimal Scan Time for the Measurement of Downstream Metabolites in Hyperpolarized 13C MRSI

  • Lee, Hansol;Lee, Joonsung;Joe, Eunhae;Yang, Seungwook;Choi, Young-suk;Wang, Eunkyung;Song, Ho-Taek;Kim, Dong-Hyun
    • Investigative Magnetic Resonance Imaging
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    • v.19 no.4
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    • pp.212-217
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    • 2015
  • Purpose: For a single time-point hyperpolarized $^{13}C$ magnetic resonance spectroscopy imaging (MRSI) of animal models, scan-time window after injecting substrates is critical in terms of signal-to-noise ratio (SNR) of downstream metabolites. Pre-scans of time-resolved magnetic resonance spectroscopy (MRS) can be performed to determine the scan-time window. In this study, based on two-site exchange model, protocol-specific simulation approaches were developed for $^{13}C$ MRSI and the optimal scan-time window was determined to maximize the SNR of downstream metabolites. Materials and Methods: The arterial input function and conversion rate constant from injected substrates (pyruvate) to downstream metabolite (lactate) were precalibrated, based on pre-scans of time-resolved MRS. MRSI was simulated using two-site exchange model with considerations of scan parameters of MRSI. Optimal scan-time window for mapping lactate was chosen from simulated lactate intensity maps. The performance was validated by multiple in vivo experiments of BALB/C nude mice with MDA-MB-231 breast tumor cells. As a comparison, MRSI were performed with other scan-time windows simply chosen from the lactate signal intensities of pre-scan time-resolved MRS. Results: The optimal scan timing for our animal models was determined by simulation, and was found to be 15 s after injection of the pyruvate. Compared to the simple approach, we observed that the lactate peak signal to noise ratio (PSNR) was increased by 230%. Conclusion: Optimal scan timing to measure downstream metabolites using hyperpolarized $^{13}C$ MRSI can be determined by the proposed protocol-specific simulation approaches.

ROLE OF SOILS IN THE DISPOSAL OF NUCLEAR WASTE

  • Lee, S.Y.
    • Korean Journal of Soil Science and Fertilizer
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    • v.19 no.3
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    • pp.251-268
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    • 1986
  • Selecting a site for the safe disposal of radioactive waste requires the evaluation of a wide range of geologic, mineralogic, hydrologic, and physicochemical properties. Although highly diverse, these properties are in fact interrelated. Site requirements are also diverse because they are influenced by the nature of the radionuclides in the waste, for example, their half-lives, specific energy, and chemistry. A fundamental consideration in site selection is the mineralogy of the host rock, and one of the most ubiquitous mineral groups is clay minerals. Clays and clay minerals as in situ lithologic components and engineered barriers may playa significant role in retarding the migration of radionuclides. Their high sorptivity, longevity (stability), low permeability, and other physical factors should make them a very effective retainer of most radionuclides in nuclear wastes. There are, however, some unanswered questions. For example, how will their longevity and physicochemical properties be influenced by such factors as radionuclide concentration, radiation intensity, elevated temperatures, changes in redox condition, pH, and formation fluids for extended periods of time? Understanding of mechanisms affecting clay mineral-radionuclide interactions under prevailing geochemical conditions is important; however, the utilization of experimental geochemical information related to physicochemical properties of clays and clay-bearing materials with geohydrologic models presents a uniquely challenging problem in that many assessments have to be based on model predictions rather than on experiments. These are high-priority research investigations that need to be addressed before complete reliance for disposal area performance is made on clays and clay minerals.

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A Study on the Business Plan Changes of Housing Complex evaluated by the "Housing Performance Grading Indication System" (주택성능등급표시제도의 개선을 위한 인정 단지의 사업계획변경 현황에 대한 실태조사 연구)

  • Lee, Sung-Ok;Bae, Cheol-Hak
    • KIEAE Journal
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    • v.11 no.6
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    • pp.43-51
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    • 2011
  • This study aims to analyze on the change status in the project plan of the housing complex as evaluated through the Housing Performance Grading Indication System. This a a system for assessing quantitatively the comprehensive, unified performance of housing by an objective standard from the design stage since January 9, 2006. As housing is a composite with various performances, it is required necessary to objectively assess the various performances from the design stage for building better housing. Thus, this study analyzed the change status and objectively described objectively it centering on the construction and structure drawings for 12 items posted in the Facility Management System_(FMS) out of examples recognized by 2011 since the implementation of the system. The changes were analyzed though observing each performance item-specific characteristics and confirming the books approved for use. In various parts, such as the site area, landscape plan, plane plan for unit, supplementary welfare facility plan, finishing materials, window size and location, the project plan was changed. These changes may result in a grading change in of the performance items of the system. This study purpose is for it to be used as a basic resource required for future system development by supplementing the limitation of the design phase and then through playing a basic role for the assessment after completion.

Safety Measure Developed Through Analysis of Firefighters' 『Investigation Report on Accidents to On-Site Workers』

  • Jo, Chang-Hyun;Kong, Ha-Sung
    • International Journal of Advanced Culture Technology
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    • v.9 no.3
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    • pp.334-344
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    • 2021
  • The study has suggested a way to minimize safety accidents found in on-site firefighting activity by analyzing firefighters' [investigation report on accidents to on-sie workers]. The study result is described as follows. First, the result of [investigation report on on-site workers] shows that while accidents are found to most frequently have occurred to low-ranking firefighting officers such as Sobangsa and Sobanggyo and firefighting officers with career of less than 5 years, fire-extinguishing activity proved to be the most prone to accidents in the category of activity. Second, analysis performed to identify variance between injury extent and area based on cause of accident shows statistically significant variance. In addition, the result of verifying difference in cause of accident based on category of activity shows significant difference with 'falling over and sliding' being the highly likely cause of accident in fire containment and rescue activities and 'reckless move' being highly likely case of accident in emergency activities. Third, the result of verifying factors behind the extent of injury done to on-site workers shows that when accident is caused by 'incomplete behavior', it was found that the extent of injury is substantial. It was also found that rescue activity is accompanied by substantial extent of injury. As a solution to this, the study suggested ways to establish, extend and operate safety-specific curriculum for entrants, develop materials regarding risk prognosis training and explicate training-related regulations, set up safety management measure for a single squad team, upgrade performance of private protection equipment, institutionalize SOP by on-site activity stage, materialize and activate swift rescue team and increase objectivity and proficiency of safety accident investigation.

Differences across countries in the impact of developers' collaboration characteristics on performance : Focused on weak tie theory (국가별 오픈소스 소프트웨어 개발자의 네트워크 특성이 개방형 협업 성과에 미치는 영향 : 약한 연결 이론을 중심으로)

  • Lee, Saerom;Baek, Hyunmi;Lee, Uijun
    • The Journal of Information Systems
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    • v.29 no.2
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    • pp.149-171
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    • 2020
  • Purpose With the advent of the 4th Industrial Revolution, related technologies such as IoT, big data, and artificial intelligence technologies are developing through not only specific companies but also a number of unspecified developers called open collaboration. For this reason, it is important to understand the nature of the collaboration that leads to successful open collaboration. Design/methodology/approach We focused the relationship between the collaboration characteristics and collaboration performance of developers who participating in open source software development, which is a representative open collaboration. Specifically, we create the country-specific network and draw the individual developers characteristics from the network such as collaboration scope and collaboration intensity. We compare and analyze the characteristics of developers across countries and explore whether there are differences between indicators. We develop a Web crawler for GitHub, a representative OSSD development site, and collected data of developers who located at China, Japan, Korea, the United States, and Canada. Findings China showed the characteristics of cooperation suitable for the form of weak tie theory, and consistent results were not drawn from other countries. This study confirmed the necessity of exploratory research on collaboration characteristics by country considering that there are differences in open collaboration characteristics or software development environments by country.

Performance Based Seismic Design State of Practice, 2012 Manila, Philippines

  • Sy, Jose A.;Anwar, Naveed;HtutAung, Thaung;Rayamajhi, Deepak
    • International Journal of High-Rise Buildings
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    • v.1 no.3
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    • pp.203-209
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    • 2012
  • The purpose of this paper is to present the state of practice being used in the Philippines for the performance-based seismic design of reinforced concrete tall buildings. Initially, the overall methodology follows "An Alternative Procedure for Seismic Analysis and Design of Tall Buildings Located in the Los Angeles Region, 2008", which was developed by Los Angeles Tall Buildings Structural Design Council. After 2010, the design procedure follows "Tall Buildings Initiative, Guidelines for Performance-Based Seismic Design of Tall Buildings, 2010" developed by Pacific Earthquake Engineering Research Center (PEER). After the completion of preliminary design in accordance with code-based design procedures, the performance of the building is checked for serviceable behaviour for frequent earthquakes (50% probability of exceedance in 30 years, i.e,, with 43-year return period) and very low probability of collapse under extremely rare earthquakes (2% of probability of exceedance in 50 years, i.e., 2475-year return period). In the analysis, finite element models with various complexity and refinements are used in different types of analyses using, linear-static, multi-mode pushover, and nonlinear-dynamic analyses, as appropriate. Site-specific seismic input ground motions are used to check the level of performance under the potential hazard, which is likely to be experienced. Sample project conducted using performance-based seismic design procedures is also briefly presented.

The study on construction of the practical testing ground of grid-connected photovoltaic system (태양광발전 계통연계 실증시험장 구축에 관한 연구)

  • Kim, Euihwan;Jang, Juyeon
    • 한국신재생에너지학회:학술대회논문집
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    • 2010.06a
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    • pp.65.2-65.2
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    • 2010
  • Currently the variety of governmental business support and research for supplying solar energy have been actively progressed. As of now, however, There are no practical testing infrastructures of grid-connected photovoltaic system which test performance of solar power facility in domestic. Therefore, in KEPRI, there is in progress construction of practical testing ground of 500 kW class grid-connected PV System for developing the evaluation of the performance technology including the Module, PCS, and etc, that is the important instrument of the PV System, in Gochang area. It analyzed the site creation work for constructing the practical testing ground and new construction of control room and the unit standards, specifications and capacity of required equipment. For the system detailed design, configuration, instrument-specific parameters established, power generation predictions of Array Type and the components of testing ground are needed to build.

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Effect of Some Parameters on Ground Effective Thermal Conductivity (지중열교환기 설치 조건이 지중 유효 열전도도에 미치는 영향)

  • Choi, Jae-Ho;Lim, Hyo-Jae;Kong, Hyoung-Jin;Sohn, Byong-Hu
    • Proceedings of the SAREK Conference
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    • 2008.11a
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    • pp.33-38
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    • 2008
  • A ground-loop heat exchanger in a ground source heat pump system is an important unit that determines the thermal performance of a system and its initial cost. The Size and performance of this heat exchanger is highly dependent on ground thermal properties. A proper design requires certain site-specific parameters, most importantly the ground effective thermal conductivity, the borehole thermal resistance and the undisturbed ground temperature. This study was performed to investigate the effect of some parameters such as borehole lengths, various grouting materials and U-tube configurations on ground effective thermal conductivity. In this study, thermal response tests were conducted using a testing device with 9-different ground-loop heat exchangers. From the experimental results, the length of ground-loop heat exchanger affects to the effective thermal conductivity. Among the various grouting materials, the bentonite-based grout with silica sand shows the largest thermal conductivity value.

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Evaluation of EC8 and TBEC design response spectra applied at a region in Turkey

  • Yusuf Guzel;Fidan Guzel
    • Earthquakes and Structures
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    • v.25 no.3
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    • pp.199-208
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    • 2023
  • Seismic performance analysis is one of the fundamental steps in the design of new or retrofitting buildings. In the seismic performance analysis, the adapted spectral acceleration curve for a given site mainly governs the seismic behavior of buildings. Since every soil site (class) has a different impact on the spectral accelerations of input motions, different spectral acceleration curves have to be involved for every soil class that the building is located on top of. Modern seismic design codes (e.g., Eurocode 8, EC8, or Turkish Building Earthquake Code, TBEC) provide design response spectra for all the soil classes to be used in the building design or retrofitting. This research aims to evaluate the EC8 and TBEC based design response spectra using the spectra of real earthquake input motions that occurred (and were recorded at only soil classes A, B and C, no recording is available at soil class D) in a specific area in Turkey. It also conducts response spectrum analyses of 5, 10 and 13 floor reinforced concrete building models under EC8, TBEC and actual spectral response curves. The results indicate that the EC8 and especially TBEC given design response spectra cannot be able to represent the mean actual spectral acceleration curves at soil classes A, B and C. This is particularly observed at periods higher than 0.3 s, 0.42 s and 0.55 s for the TBEC design response spectra, 0.54 s, 0.65 s and 0.84 s for the EC8 design response spectra at soil classes A, B and C, respectively. This is also reflected to the shear forces of three building models, as actual spectral acceleration curves lead to the highest shear forces, followed by the shear forces obtained from EC8 and, then, the TBEC design response spectra.

A New Search for Dance Space ; A comparative Study of Spaces between Theaters and Museums (무용공간의 새로운 공간 탐색 ; 극장과 미술관의 공간 연구)

  • Park, Sung-Hye
    • The Journal of the Korea Contents Association
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    • v.19 no.8
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    • pp.44-57
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    • 2019
  • As dance performances in the theater space are centered on text, they have plots and make characters stand out. They also emphasize expressivity and technique, and their recognition of space is very modern and typical of dichotomous Cartesian thinking. The museum space has many similarities with the theater space in that it is a result of modernity and granted authority to present arts. The performances in museums place value more on the presence than on the representation. For this reason, works in museums, which are frequently presented in recent years, are mainly works of site-specific or performative concepts. Now, rather than being able to obtain from aesthetics defined as works, the museum is assured its own aesthetic production and justification, paying attention to the performance as an event occurring now and here.