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Two Cases of Congenital Laryngeal Web Presenting in Complaint of Hoarseness (음성 장애를 주소로 내원한 선천성 성대 격막 2예)

  • Moon, Myung-Gi;Chae, Ryung;Lee, Sang-Hyuk;Jin, Sung Min
    • Journal of the Korean Society of Laryngology, Phoniatrics and Logopedics
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    • v.25 no.2
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    • pp.99-103
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    • 2014
  • A laryngeal web is connective tissue covered with epithelium stretching between both sides of the true vocal cords. Laryngeal webs were first reported by Fleischmann in 1882, and they cause upper airway obstruction and abnormalities of phonation. Congenital webs result from an arrest of reabsorption of the epithelium of the larynx at the tenth week of the fetus. The most common site of webbing is the anterior commissural glottic area, followed by other glottic areas and rarely subglottic or supraglottic areas. We have experienced two cases of congenital laryngeal webs. The webs were operated in two different methods. The first was excised under magnified vision through a laryngoscope, with a silastic keel secured between the raw surfaces of the separated mucosa. In the second case, the deepithelialized surfaces were exposed for a certain time length to mitomycin C to prevent postoperative webbing. We, hereby, report our experience of the diagnosis and management of two cases of a rare entity known as the congenital laryngeal web, and discuss the results with relevant studies.

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Results of Treatment of Rhabdomyosarcoma in Children (소아에서의 횡문근육종의 치료 결과)

  • Kim, Byung-Soo;Moon, Suk-Bae;Lee, Seong-Cheol;Jung, Sung-Eun;Park, Kwi-Won
    • Advances in pediatric surgery
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    • v.14 no.2
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    • pp.164-172
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    • 2008
  • The survival rate for rhabdomyosarcoma (RMS) has significantly improved after the introduction of combined multimodality treatment. We report the 20-year treatment outcome of pediatric rhabdomyosarcoma in a single institution. The medical records of 16 patients treated for rhabdomyosarcoma between December 1986 and August 2007 at the Department of Pediatric Surgery, Seoul National University Children's Hospital, were retrospectively reviewed. Mean age at diagnosis was 7.1 years (range: 1.3 -14.2 years). Retroperitoneum was the most common primary site (n=7, 43.8 %), and embryonal type was predominant (n=11, 6 %). Before the treatment, most patients were in advanced TNM stage (stage III 50 %, IV; 25 %). The patient distribution according to the Intergroup Rhabdomyosarcoma Study Clinical Grouping System (IRS-CGS) was as follows; Group I 31.3 %, Group II 12.5 %, Group III 31.3 % and Group IV 25 %. Patients were classified into three groups according to the extent of resection of the primary tumor; complete resection (CR, n=5; 31.3 %), gross total resection (GTR, n=7; 43.8 %) and incomplete resection (IR, n=4; 25 %). Recurrence was observed in 9 patients (56.3 %) while there was no recurrence in CR patients. All patients with recurrence were identified as moderate or high-risk according to the IRS-V Risk Group. Pre-treatment TNM stage of RMS in our institution was advanced with aggressive clinical feature, however postsurgical conditions according to IRS-CGS were similar to the previous reports by IRS. This suggests that down-staging of IRS-CGS was achieved with multimodality treatment with CR or GTR. It also suggests that complete resection is the most important prognostic factor in the treatment of RMS in children. Patients classified as moderate or high-risk need close follow-up due to high recurrence rate. In case of localized recurrence, better outcome may be achieved with multimodality treatment including limited surgery.

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Treatment of Gingival Invagination after Orthodontic Treatment with Extraction (발치 교정치료시 치은 함입에 관한 치은 처치)

  • Kim, Yun-Sang;Cho, Jin-Hyoung;Cho, Jin-Woo
    • Journal of Dental Rehabilitation and Applied Science
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    • v.28 no.1
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    • pp.79-86
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    • 2012
  • In most patients with severe crowding or lip protrusion, orthodontic treatment with tooth extraction is done. In these patients, even though space is closed after orthodontic treatment, gingival invagination is observed on the extracted site. Since there are possibilities of space recurrence and regional periodontic problems occurrence, periodontic treatment is necessary on the gingival invagination region. This case was a 16 year old female with a chief complaint of crooked teeth. Since her maxillary premolars were already extracted a few years ago at a local dental clinic, orthodontic treatment was done by extracting mandibular premolars. Unlike maxillary premolar regions, gingival invagination occurred in mandibular premolar regions and gingival flattening was done by excising the gingival invaginated region. Gingival flattening was done once on the left side, twice on the right side and showed stable results. This is a case report of a patient that was prone to gingival invagination after orthodontic treatment with extraction and was treated with gingival flattening.

Clinical use of Platelet Rich Fibrin(PRF) in Various Hard and Soft Tissue Defect : Case Report (혈소판 유래 섬유소(Platelet Rich Fibrin(PRF))를 이용한 골결손부의 치료 : 증례보고)

  • Chee, Young-Deok;Go, Seo-Wook
    • Journal of Dental Rehabilitation and Applied Science
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    • v.23 no.4
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    • pp.303-312
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    • 2007
  • Recently several studies have been developed not only to apply bone materials to bony defect, but also to use osteogenic and osteoinductive materials to form bone more effectively. In 1998 Mark et al applied gel formation of PRP(platelet-rich plasma) in bony transplantation for mandibular reconstruction as one of the method of stimulating bone formation in maxillofacial area, which is contain of varies growth factors. After he reported that PRP accelerate bone formation, which is used in varies bone transplantation and augmentation with a good result. Especially there are amount of growth factors in PRP, and PRP increase angiogenesis, cell division, and mesenchymal cell growth. Moreover it is capable of osteoconduction, hemostatitis, anti-infection, forming the shape at transplantation, ease of handling, and recipient site stability. So it is known that success rate is high in bone transplantation. However PRP need tissue adhesive to make plasma to solid form. Thrombin and calcium chloride, component of PRP, is extracted from autogenic donor. So it is expensive to extract and there is possibility of hepatitis, AIDS, and hematogenous metastasis. After all, tissue adhesive have the limitation and danger of use. So we are willing to introduce that we had get some idea after using PRF(platelet-rich fibrin) in the various hard and soft tissue bony defect, which is self extracted simply and contain growth factors.

Evidence of Spin Reorientation by Mössbauer Analysis

  • Myoung, Bo Ra;Kim, Sam Jin;Kim, Chul Sung
    • Journal of Magnetics
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    • v.19 no.2
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    • pp.126-129
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    • 2014
  • We report the crystallographic and magnetic properties of $Ni_{0.3}Fe_{0.7}Ga_2S_4$ by means of X-ray diffractometer (XRD), a superconducting quantum interference device (SQUID) magnetometer, and a M$\ddot{o}$ssbauer spectroscopy. In particular, $Ni_{0.3}Fe_{0.7}Ga_2S_4$ was studied by M$\ddot{o}$ssbauer analysis for evidence of spin reorientation. The chalcogenide material $Ni_{0.3}Fe_{0.7}Ga_2S_4$ was fabricated by a direct reaction method. XRD analysis confirmed that $Ni_{0.3}Fe_{0.7}Ga_2S_4$ has a 2-dimension (2-D) triangular lattice structure, with space group P-3m1. The M$\ddot{o}$ssbauer spectra of $Ni_{0.3}Fe_{0.7}Ga_2S_4$ at spectra at various temperatures from 4.2 to 300 K showed that the spectrum at 4.2 K has a severely distorted 8-line shape, as spin liquid. Electric quadrupole splitting, $E_Q$ has anomalous two-points of temperature dependence of $E_Q$ curve as freezing temperature, $T_f=11K$, and N$\acute{e}$el temperature, $T_N=26K$. This suggests that there appears to be a slowly-fluctuating "spin gel" state between $T_f$ and $T_N$, caused by non-paramagnetic spin state below $T_N$. This comes from charge re-distribution due to spin-orientation above $T_f$, and $T_N$, due to the changing $E_Q$ at various temperatures. Isomer shift value ($0.7mm/s{\leq}{\delta}{\leq}0.9mm/s$) shows that the charge states are ferrous ($Fe^{2+}$), for all temperature range. The Debye temperature for the octahedral site was found to be ${\Theta}_D=260K$.

Management Efficiency Estimation of Social Enterprises with Data Envelopment Analysis (사회적 기업의 자료포락분석(DEA)을 통한 경영효율성 평가)

  • Lee, Sang-Yun;Lim, Sungmook;Chae, Myungsin
    • Journal of Korean Society of Industrial and Systems Engineering
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    • v.40 no.2
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    • pp.121-128
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    • 2017
  • This paper was to evaluate social enterprises' management efficiency with Data Envelope Analysis (DEA). The data was based on the 168 social enterprises' of annual performance reports published in 2015. The research focused on to measure both financial efficiency and social impact of the companies simultaneously. To apply DEA, the paper classified the enterprises into seven types based on types of socal impacts which each company provides before the estimation of the efficiency. The research results showed that group D, which employes disadvantaged people, provides social services and shares resources was the most efficient group and had higest net worths in Pure Technical Efficiency. In contrast, Group B, which only employs social advantage people and provides social service, was the least efficient one. The research suggests a practical and efficient framework in measuring social enterprises' management efficiency, including both the financial performance and social impacts simultaneously with their self-publishing reports. Because the Korea Social Enterprise Promotion Agency does not open business reports which social enterprises submit each year, there are basic limitations on researchers attempting to analyse with data from all social enterprises in Korea. Thus, this study dealt with only 10% of the social enterprises which self-published their performance report on the Korea Social Enterprise Promotion Agency's web site. Regardless of these limitations, this study suggested substantial methods to estimate management efficiency with the self-published reports. Because self-publishing is increasing each year, it will be the main source of information for researchers in examining and evaluating social enterprises' financial performance or social contribution. The research suggests a practical and efficient framework in measuring social enterprises' management efficiency, including both the financial performance and social impacts simultaneously with their self-publishing reports. The research results suggest not only list of efficient enterprises but also methods of improvement for less efficient enterprises.

Interstitial Radium Implantation and Cobalt-60 Irradiation of the Tongue Cancer (IbidI) (설암의 조직간내 라디움치료에 관하여)

  • 안경성;박주방;윤용규
    • Proceedings of the KOR-BRONCHOESO Conference
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    • 1972.03a
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    • pp.16.1-16
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    • 1972
  • In 1971 there were 5 cases of the tongue cancer in stage I & II treated concomitantly with interstitial radium implantation and Cobalt-60 irradiation at the Yonsei University Hospital Cancer Center. This is the interim report of the course of the primary site of those treated cases.

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Microstructure investigation of iron artifacts excavated from Sungseonsa Temple in Chungju city (충주 숭선사지 출토 철제유물의 미세조직 분석)

  • Yu, Jae-Eun;Go, Hyeong-Sun;Yi, Jae-Seong
    • 보존과학연구
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    • s.24
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    • pp.187-213
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    • 2003
  • Sungseonsa Temple site in Chungju city in Chungcheongbuk-doProvince is written in "Goryeosa" as a building for Queen Sinmyeongsunseong, the mother of Gwangjong in AD 954 in Goryeo Dynasty. The museum in Chungcheong University takes charge of the excavation for 3 times from 2000 to 2002 and identified that its construction was carried out till Joseon Dynasty. Among the iron artifacts from the first excavation such as a weeding hoe, a hand knife, a lock, two nails and a plow which had conservation treatments, the sample was collected. Its micro-structure and method of manufacture were investigated. Excavation report for those artifacts has not published yet, therefore, the date of each artifacts is not clearly confirmed. The samples were collected from each part of the objects and then embedded in epoxy resin and etched with nitric acid. The examination of its microstructure is carried out under the microscope and the hardness values were measured by Vickers hardness tester. From the results, some artifacts show different manufacture method sin the each parts. The forming processes of the iron weeding hoe and the iron sickle are similar but the blade of iron weeding hoe was strengthened by carbonization whereas the blade of the iron sickle was done by quenching. The hand knife and the nails were produced through almost same methods and shows similar microstructures. The hand knife seems to be made by repeated beating and folding in low temperature resulting in fine crystallization, but the nail shows large crystallization due to processes in high temperature. Lock is made of white cast iron, that does not show any heat treatment.

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Preparation of Radiological Environmental Impact Assessment for the Decommissioning of Nuclear Power Plant in Korea (국내 원전 해체시 방사선환경영향평가 방안)

  • Lee, Sang-Ho;Seo, Hyung-Woo;Kim, Chang-Lak
    • Journal of Nuclear Fuel Cycle and Waste Technology(JNFCWT)
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    • v.16 no.1
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    • pp.107-122
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    • 2018
  • Kori unit 1, the oldest commercial nuclear power plant in South Korea, was permanently shut down in June 2017. There are a lot of things to consider in decommissioning nuclear power plants, and one of them is the radiological environmental impact assessment. Performed to promote the health and safety of residents around the nuclear power plant, radiological environmental impact assessment aims to confirm that off-site radiological dose from radioactive material released from the facility does not exceed the regulatory criteria. There are three main parts of environmental impact assessment: pre-decommissioning environmental monitoring, environmental monitoring during decommissioning, and impact on nearby residents. At present, although the Korea Nuclear Safety Act stipulates that radiological environmental impact assessment resulting from decommissioning should be carried out, the details have not been specified. Therefore, this paper compares and analyzes guidelines for evaluation of radiological environmental impacts of nuclear power plants overseas, and presents a draft on the assessment of radiological dose resulting from decommissioning according to the Korean situation.

Molecular Identification of Korean Mountain Ginseng Using an Amplification Refractory Mutation System (ARMS)

  • In, Jun-Gyo;Kim, Min-Kyeoung;Lee, Ok-Ran;Kim, Yu-Jin;Lee, Beom-Soo;Kim, Se-Young;Kwon, Woo-Seang;Yang, Deok-Chun
    • Journal of Ginseng Research
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    • v.34 no.1
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    • pp.41-46
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    • 2010
  • Expensive herbs such as ginseng are always a possible target for fraudulent labeling. New mountain ginseng strains have occasionally been found deep within mountain areas and commercially traded at exorbitant prices. However, until now, no scientific basis has existed to distinguish such ginseng from commonly cultivated ginseng species other than by virtue of being found within deep mountain areas. Polymerase chain reaction (PCR) analysis of the internal transcribed spacer has been shown to be an appropriate method for the identification of the most popular species (Panax ginseng) in the Panax ginseng genus. A single nucleotide polymorphism (SNP) has been identified between three newly found mountain ginseng (KGD4, KGD5, and KW1) and already established Panax species. Specific PCR primers were designed from this SNP site within the sequence data and used to detect the mountain ginseng strains via multiplex PCR. The established multiplex-PCR method for the simultaneous detection of newly found mountain ginseng strains, Korean ginseng, and foreign ginseng in a single reaction was determined to be effective. This study is the first report of scientific discrimination of "mountain ginsengs" and describes an effective method of identification for fraud prevention and for uncovering the possible presence of other, cheaper ginseng species on the market.