• Journal of the Korean Association of Oral and Maxillofacial Surgeons
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• v.27 no.6
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• pp.498-510
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• 2001

Distraction osteogenesis refers to the biological process responsible for new bone formation between bone segments by gradual distraction after osteotomy. For the past several years, various inconveniences including a protracted consolidation period that requires patients to wear a distractor frame longer, as well as higher medical costs, have not been remedied by improvements in osteotomy, distraction rate and monitoring system. Furthermore, side effects such as pin tract infections and soft tissue swelling may arise due to the long treatment period. These drawbacks form the rationale of this study which purports to seek a method by which the consolidation period can be reduced. This paper examines how platelet-rich plasma(PRP), known to facilitate osteogenesis, influences bone formation when applied in distracted area. Ten mongrel dogs, which were made to wear external distractor frames after osteotomy in both sides of the mandible, were used as subjects. After a 7day period of latency, distraction was carried out at a rate of 1mm/day for 14 consecutive days. After the onset of distraction, 2ml of PRP and a mixture of calcium gluconate and thrombine were injected into the center of the distracted callus on the left side of the mandible. The left was injected with PRP while the right side was set as the control site without PRP treatment. Execution at the onset of distraction and in 2 weeks, 4 weeks and 8 weeks after the consolidation period, clinical and radiographic tests, bone mineral density examination, histological examination and histomorphometric analysis were conducted to compare both sides. The results are summarized as follows: 1. Based on the clinical examination at two weeks, more remarkable cortical bone formation was found on the buccal and lingual side of the distracted area in the PRP treatment site than in the control site. No visual difference was found between the PRP treatment site and the control site at four eight weeks. 2. Based on the radiological examination, a distinct increase in the radiopaque appearance of the PRP treatment site was revealed at two weeks, but this increase appeared to slow down at four and eight weeks. 3. Examination of bone mineral density revealed a significant difference at two weeks with the PRP treatment site yielding density two times higher than the control site. This difference lessened after four weeks, and disappeared at eight weeks. 4. The histomorphometric examination revealed that about 20% more bony trabeculae area(20%, higher) was formed in the PRP treatment site than in the control site. In conclusion, it can be said that PRPs effect on stimulating bone formation in the PRP treatment site manifest as early as two weeks. Trabeculae formation likewise increased throughout the whole period. If this result can be applied to humans, the consolidation period can be reduced by injecting PRP into the distracted area.

• Journal of the Korean Geotechnical Society
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• v.34 no.5
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• pp.19-35
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• 2018

The necessity of predicting the spatial information of the site-specific seismic response, which is essential information for the comprehensive earthquake disaster countermeasures, is increasing for the mid-west urban areas where the earthquake-induced damages can be increased due to frequent occurrence of mid-scale earthquake such as 2016 Gyeongju Earthquake and 2017 Pohang Earthquake. Especially, researches on strategic securing of site survey datasets and understanding the site-specific site response characteristics were conducted for Gyeonggi-do, South Korea. In this study, a GIS-based framework for site-specific assessment of site response and induced vulnerable area in Gyeonggi-do, South Korea was proposed. Geo-Data based on GIS platform was constructed for regional estimation of geotechnical characteristics by collecting borehole and land coverage datasets. And the geo-spatial grid information was developed for deriving spatial distribution of geotechnical layer and site response parameters based on the optimization of the geostatistical interpolation method. Accordingly, base information for Improving earthquake preparedness measures was derived as seismic zonation map with administrative sub-units considering the quantitative site effect of Gyeonggi-do.

• The Journal of Korean Physical Therapy
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• v.18 no.2
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• pp.25-34
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• 2006

Purpose: This study conducted quantitative sensory test and nociceptive flexion reflex(NFR) measurement to examine degree of pain depending on polarity of high voltage pulsed current(HVPC) of hyperalgesia site in hyperalgesia rat by local thermal injury. mechanical pain threshold, thermal pain threshold and root mean square of NFR were measured. Methods: This study was conducted with control group I of hyperalgesia rat at hind paw by thermal injury and experimental groups divided into cathodal HVPC group II, anodal HVPC group III and alternate HVPC group IV. It measured pain threshold and root mean square(RMS) of NFR and obtained the following results. Results: Mechanical pain threshold of hyperalgeisa site was significantly increased at groups II, III and IV applying HVPC group compared to control group, but there was no difference among HVPC groups. Thermal pain threshold of hyperalgesia site showed a significant increase in group II. Group III showed significant difference after 4 days of hyperalgesia. RMS of NFR at hyperalgeisa site was significantly reduced in group II after 2 days of hyperalgesia. Group III showed significant decrease after 5 and 6 days of hyperalgesia. Conclusion: Consequently it was found that application of HVPC of hyperalgesia site increased pain threshold at hyperalgesia site by mechanical stimuli and thermal stimuli. NFR by electrical stimuli was similar to pain threshold by mechanical stimuli. Effects by polarity of HVPC showed the greatest reduction of hyperalgesia when cathodal electrode was used.

• Journal of Korean Society of Forest Science
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• v.103 no.2
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• pp.240-247
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• 2014

This study was conducted as a restoration research in a mountain stream of hydrologic cycle system, which is a type of microsites purposely changing vegetation. The status of vegetation in the three experimental sites, water purification site, small dammed pole site, and aquatic plant restoration site, and one control site within the area of the mountain forest stream were investigated in three different periods, namely before sites restoration, year of sites restoration, and year after sites restoration. After one year of restoration, number of vegetation was increased in the small dammed pool and control site respectively. Vegetation coverage ratio of Zizania latifolia was increased at the water purification area. The effects of habitats restoration appeared to be good a year after the restoration of the experimental sites, in terms of families and species composition of the introduced vegetation, and stream flow. Therefore, the results of the study strongly suggest that fairly effective ways to restore and reproduce degrading mountain hydroecological habitats are by way of forming pool sites and small dams in intermittent mountain streams and re-vegetating with selected plants.

• Journal of Korean Academy of Nursing
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• v.31 no.6
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• pp.1067-1076
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• 2001

This study was to developed to create a CD-ROM and an educational program for the prevention of sexual harassment and violence and to contribute to the perception and add to the coping of the victims of sexual harassment and violence as well as the child, parents, and teachers. Method: The study's methods were literature reviews, surveys, and assessments of the negotiation process for educational needs of sexual harassed and abused children. Result: The sexual harassment and violence prevention program will contain four subjects : 1) sexual development of a preschool child, 2) characteristics of sexual harassment and violence of a preschool child, 3) safe sex, early detection of sexual violence syndrome, and coping strategies. The CD-RON was composed from three sites. The first was a child site, the second was a parent/teacher site, and the third was a game site for evaluations. The child site consisted of 10 possible scenarios of sexual harassment and violence that a child could experience. The parent/teacher site consisted of knowledge and information for prevention and coping strategies for sexual harassment and violence. At the end of each situation question and answer sections that were used for formative evaluation. Also, the game site could be a summative evaluation. Conclusion: The effects of this program and the CD-ROM were based of the promotion of reverence for humanity and gender equality for preschool childen. Eventually, children, parents, and teachers will have prevention and coping ability that will reduce the occurrence of sexual harassment and violence in Korea

• Journal of Ecology and Environment
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• v.38 no.3
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• pp.281-291
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• 2015

To clarify the effects of forest fire on the carbon budget of a forest ecosystem, this study compared the seasonal variation of soil respiration, net primary production and net ecosystem production (NEP) over the year in unburned and burned Pinus densiflora forest areas. The annual net carbon storage (i.e., NPP) was $5.75t\;C\;ha^{-1}$ in the unburned site and $2.14t\;C\;ha^{-1}$ in the burned site in 2012. The temperature sensitivity of soil respiration (i.e., $Q_{10}$ value) was higher in the unburned site than in the burned site. The annual soil respiration rate was estimated by the exponential regression equation with the soil temperatures continuously measured at the soil depth of 10 cm. The estimated annual soil respiration and heterotrophic respiration (HR) rates were 8.66 and $4.50t\;C\;ha^{-1}yr^{-1}$ in the unburned site and 4.08 and $2.12t\;C\;ha^{-1}yr^{-1}$ in the burned site, respectively. The estimated annual NEP in the unburned and burned forest areas was found to be 1.25 and $0.02t\;C\;ha^{-1}yr^{-1}$, respectively. Our results indicate that the differences of carbon budget and cycling between both study sites are considerably correlated with the losses of living plant biomass, insufficient nutrients and low organic materials in the forest soil due to severe damages caused by the forest fire. The burned Pinus densiflora forest area requires at least 50 years to attain the natural conditions of the forest ecosystem prior to the forest fire.

• Journal of Ecology and Environment
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• v.37 no.2
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• pp.69-79
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• 2014

Soil organic carbon (SOC) in the Arctic is vulnerable to climate change. However, research on SOC stored in the high Arctic regions is currently very limited. Thus, this study was aimed at understanding the distribution and characteristics of SOC with respect to geomorphology and vegetation in Svalbard. In August 2011, soil samples were collected near the Vestre Lov$\acute{e}$nbreen moraine. Sampling sites were chosen according to altitude (High, Mid, and Low) and differences in levels of vegetation establishment. Vegetation coverage, aboveground biomass, and SOC contents were measured, and density-size fractionation of SOC was conducted. The SOC content was the highest in the Mid site ($126.9mg\;g^{-1}$) and the lowest in the High site ($32.1mg\;g^{-1}$), although aboveground biomass and vegetation coverage were not different between these two sites. The low SOC content measured at the High site could be related to a slower soil development following glacial retreat. On the other hand, the Low site contained a high amount of SOC despite having low vegetative cover and a high ratio of sand particles. These incompatible relationships between SOC and vegetation in the Low site might be associated with past site disturbances such as runoff from snow/glacier melting. This study showed that geomorphological features combined with glacier retreat or melting snow/glacier effects could have affected the SOC distribution and vegetation establishment in the high Arctic.

• Korean Journal of Animal Reproduction
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• v.25 no.4
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• pp.381-388
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• 2001

The present study was designed to obtain porcine growth hormone binding protein (pGHBP) improved biological activation as derived mutation in binding site with growth horlnone (GH). A 756 bp of fragment encoding the extracellular domain of pGHBP gene was cloned from the total RNA of porcine fat tissue by reverse transcriptase polymerase chain reaction (RT-PCR) and created mutation in positions 26 and 122 using site-directed mutagenesis method. Position 26 is one and it is near to get on five potential N-linked glycosylation sites located in the extracellular domain of porcine growth hormone receptor known to have a direct influence on combination with GH. Position 122 is known as one of conformational epitope in bovine. It was over-expressed in E. coli using pET-32(c) expression vector and precisely purified by S-protein agarose and enterokinase. In our results, we was obtained pmGHBP of 30 kDa. It suggests to study the effects of the pmGHBP on cell proliferation in vitro and growth rate in vivo after administration.

• Proceedings of the Korean Institute Of Construction Engineering and Management
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• 2008.11a
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• pp.712-715
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• 2008

The construction wastes rapidly increase because of redevelopment, the development of new urbanization of large-scale land development, the expansion of social infrastructure. As one of the ways to recycle construction waste to be recycled directly. This case, recycling of materials uses up most of recycled aggregate can be secured reliably. As a result, a decrease in the amount of materials brought in or taken out of the site, the cost of transportation, carbon dioxide emission, and traffic can be reduced. Economic, social and environmental effects can be expected. Therefore, this study of the construction waste "Site-Recycling" to enable the construction waste from the occurrence of "site-recycling" that can be processed in batches to apply the "Site-Recycling Simulation Program" is to develop the algorithms.

• Journal of the Korean GEO-environmental Society
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• v.10 no.1
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• pp.35-41
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• 2009

It is necessary to consider the site amplification for estimating SSI (soil structure interaction) and seismic source with more confidence. The horizontal to vertical (H/V) ratio technique in spectral domain is one of several techniques to estimate empirical site transfer function. The technique, originally proposed by Nakamura (1989), is applied to analyze the surface waves in the microtremor records. However, the application of this technique has been widened to the shear wave energy of strong motions for estimating site amplification. The purpose of this paper is to estimate spectral ratio using observed data at the seismic stations distributed within Southern Korean Peninsula from the Fukuoka earthquake including 11 aftershocks. The results show that each station has the its own characteristics of the specific resonance, high-band, and low-band frequency. The characteristics of the resonance frequency is more important because the quality of the seismic records are dependent on the resonance frequency. The result can be used for the study of site classification and removal of the site amplification effects from observed records can give us more reliable seismic source parameters.