• Journal of Korean Society of Coastal and Ocean Engineers
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• v.15 no.4
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• pp.232-241
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• 2003

The interaction of incident monochromiatic waves with N bottom-mounted porous circular cylinders is investigated in the frame of three-dimensional linear potential theory. The fluid domain is divided into N+l regions i.e. a single exterior region and N interior regions, and the diffraction potential in each fluid region is expressed by an eigenfunction expansion method (Williams and Li,2000). The analytic results show that the porous structure reduces both the wave forces and the run-up wave around the cylinder. To verify the developed model, the systematic model test with a line array of porous cylinders is conducted at the wave tank (30m$\times$7m$\times$1.5m). The analytic results are in good agreement with the experimental results within measured frequency range. It is concluded that the breakwater constructed with an array of porous circular cylinders shows the performance of an effective wave barrier together with the seawater-exchange effect and is considered to have vast potentials for the use of seawater-exchanging breakwater in the future.

• Journal of the Korean Society of School Health
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• v.21 no.2
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• pp.35-46
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• 2008

Purpose: This study was a part of preliminary survey for establishing Korean HPS(Health Promoting School) model which was originally suggested by WHO. Methods: Three elementary and middle schools were sampled in urban and rural area across three level of social-economic status, and survey was conducted on one class in each grade by random selection. To measure mental health and social and familial factors, self-esteem scale, self-efficacy scale, depression scale, family cohesion scale, parent-child communication scale, adolescent's mental health and problem behavior questionnaire(AMPQ), and other question items about family status and economic level were conducted. Students' mental health level was compared by region, sex, grade, and other familial and economic factors. Results: Familial and social factors such as economical and educational level of parents, number of family members were different between rural and urban area. Also, students of rural area got lower scores at self-esteem, self-efficacy, but higher scores at extroverted problem behavior than their urban counterparts. In pre-school students, high grade students' self-esteem, and family cohesion scores were lower than low grade students. And sexual differences were found across problem behavior domain and region in middle school students. Especially, the students of single-parent family and lower economic family got insistently low scores at various mental health related scales. Conclusion: These results should be considered, when the HPS model is designed and applied in Korea.

• Ocean and Polar Research
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• v.33 no.2
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• pp.159-169
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• 2011

Antifreeze proteins (AFPs) have ice binding affinity, depress freezing temperature and inhibit ice recystallization which protect cellular membranes in polar organisms. Recent structural studies of antifreeze proteins have significantly expanded our understanding of the structure-function relationship and ice crystal growth inhibition. Although AFPs (Type I-IV AFP from fish, insect AFP and Plant AFP) have completely different fold and no sequence homology, they share a common feature of their surface area for ice binding property. The conserved ice-binding sites are relatively flat and hydrophobic. For example, Type I AFP has an amphipathic, single ${\alpha}$-helix and has regularly spaced Thr-Ala residues which make direct interaction with oxygen atoms of ice crystals. Unlike Type I AFP, Type II and III AFP are compact globular proteins that contain a flat ice-binding patch on the surface. Type II and Type III AFP show a remarkable structural similarity with the sugar binding lectin protein and C-terminal domain of sialic acid synthase, respectively. Type IV is assumed to form a four-helix bundle which has sequence similarity with apolipoprotein. The results of our modeling suggest an ice-binding induced structural change of Type IV AFP. Insect AFP has ${\beta}$-helical structure with a regular array of Thr-X-Thr motif. Threonine residues of each Thr-X-Thr motif fit well into the ice crystal lattice and provide a good surface-surface complementarity. This review focuses on the structural characteristics and details of the ice-binding mechanism of antifreeze proteins.

• Korean Journal of Cognitive Science
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• v.11 no.2
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• pp.19-35
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• 2000

Learning by examples has proven to be an efficient method in mastering various subjects including programming languages. This study hypothesizes that the number of examples and the type of examples are two significant dimensions that influence the performance of learning programming languages by examples. A set of experiments was conducted to investigate the impacts of the two dimensions in the domain of JAVA programming. The results showed that providing two examples is more effective than providing only one example even though significantly more explanations are attached to the single example. Among the 'two-example' groups, the group that was given functionally similar examples performed better than those with functionally dissimilar examples. Explanations for these results are provided in this paper based on the behavioral patterns of individual subjects in terms of time and frequency. This paper concludes with the implications of the study results for the development of effective tutoring systems for programming languages.

• Journal of Ocean Engineering and Technology
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• v.21 no.3 s.76
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• pp.46-51
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• 2007

A multi-purpose environmental monitoring system has been developed as a commercially available standard using the technique of hetero-core spliced fiber optic sensors, for the purposes of monitoring large-scale structures and preserving natural environments. The monitoring system has been tested and evaluated in a possible outdoor condition, in view of the full-scale operation at actual sites to be monitored. Additionally, the developed system in this work conveniently provides us with various options of sensor modules intended for monitoring such physical quantities as displacement, distortion, pressure, binary states, and liquid adhesion. Two channels of optical fiber line were monitored in each channel, three displacement sensor modules were connected in series, in order to examine the performance to a pseudo-cracking experiment in the outdoor situation and to clarify temperature influences an the system, in terms of the coupling of optical connectors and the OTDR stability. The results from the pseudo-cracking experiment agreed with the actual cracks, by means of calculation, based an the detected displacement values and their geometrical arrangement of the used sensor modules. The temperature change, ranging from 10 to $20^{\circ}C$ resulting from the 10-days free running operation, was found to influence the system stability of ${\pm}10{\mu}m$, primarily due to the coupling instability of the used optical connectors. It was found that fusion splicing, rather than the use of connectors, reduced the fluctuation dawn to ${\pm}2{\mu}m$. The specification and performance of various option modules have been demonstrated to show the capability of inspecting various physical quantities by use of the single system, which would be suitable for multi-purpose environmental monitoring.

• Journal of KIISE:Computer Systems and Theory
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• v.30 no.3_4
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• pp.168-185
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• 2003

This paper presents a progressive algorithm that not only can narrow down the search domain in the course of face identification but also can fast reconstruct various 3D objects from a sketch drawing. The sketch drawing, edge-vertex graph without hidden line removal, which serves as input for reconstruction process, is obtained from an inaccurate freehand sketch of a 3D wireframe object. The algorithm is executed in two stages. In the face identification stage, we generate and classify potential faces into implausible, basis, and minimal faces by using geometrical and topological constraints to reduce search space. The proposed algorithm searches the space of minimal faces only to identify actual faces of an object fast. In the object reconstruction stage, we progressively calculate a 3D structure by optimizing the coordinates of vertices of an object according to the sketch order of faces. The progressive method reconstructs the most plausible 3D object quickly by applying 3D constraints that are derived from the relationship between the object and the sketch drawing in the optimization process. Furthermore, it allows the designer to change viewpoint during sketching. The progressive reconstruction algorithm is discussed, and examples from a working implementation are given.

• Journal of KIISE:Software and Applications
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• v.35 no.8
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• pp.512-521
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• 2008

Web-based information services should be evaluated for accessibility and usability with various types of Internet Web-browsing devices, interacting with web information servers. A reliable ubiquitous Web information server, accessible and usable with a variety of Web-browsing devices (e.g. a full-browsing mobile phone), should be a unified center for personalized ubiquitous Web information services as well as for business models based on personalized advertisements. We studied an estimation of the accessibility and usability in Web interaction for personalized ubiquitous Web information services, as metrics for real-time estimation. We show empirical results based on implementation and experiments in Korea, Japan and China, using a test-bed Web site ('ktrip.net') and single-character Korean domain names (e.g. 김.net, 이.net, 박.net, 최.net, ㄱ.net, ㄴ.net ... ㅎ.net, ㅏ.net, ... ㅔ.net, ㄱ.com, ㄴ.com ... ㅎ.com).

• The Journal of the Korea Contents Association
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• v.14 no.5
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• pp.8-17
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• 2014

Petascale systems(so called supercomputers) have been mainly used for supporting communication-intensive and tightly-coupled parallel computations based on message passing interfaces such as MPI(HPC: High-Performance Computing). On the other hand, computing paradigms such as High-Throughput Computing(HTC) mainly target compute-intensive (relatively low I/O requirements) applications consisting of many loosely-coupled tasks(there is no communication needed between them). In Korea, recently emerging applications from various scientific fields such as pharmaceutical domain, high-energy physics, and nuclear physics require a very large amount of computing power that cannot be supported by a single type of computing resources. In this paper, we present our HTCaaS(High-Throughput Computing as a Service) which can leverage national distributed computing resources in Korea to support these challenging HTC applications and describe the details of our system architecture, job execution scenario and case studies of various scientific applications.

• BMB Reports
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• v.34 no.3
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• pp.201-205
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• 2001

Thionins are a family of low molecular weight cysteine-rich antimicrobial peptides. We isolated a cDNA encoding thionin gene from a flower bud cDNA library of Chinese cabbage (CFT). The gene contains 611 by nucleotides with 60 bp, and 150 by untranslated regions at its N- and C-terminal, respectively. The deduced amino acid sequence encoded 133 amino acids containing precursor polypeptide. The protein reveals that the precursor has a tripartite structure: a putative signal sequence at the N-terminus, followed by a mature thionin peptide, and a C-terminal acidic domain, which facilitates transport of the mature thionin through membrane. Genomic Southern blot analysis suggests that the CFT gene may be present as a single or two copy gene in the Chinese cabbage genome. Northern blot analysis shows that the gene is specifically expressed in flowers, but not in leaves, stems, or roots. When we analyzed the antifungal activity of the recombinant CFT protein, which was expressed in E. coli using the truncated cDNA region corresponding to the mature protein part, it was not active on fungal growth inhibition.

• Parasites, Hosts and Diseases
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• v.56 no.2
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• pp.153-165
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• 2018

Development of an effective vaccine is critically needed for the prevention of malaria. One of the key antigens for malaria vaccines is the apical membrane antigen 1 (AMA-1) of the human malaria parasite Plasmodium falciparum, the surface protein for erythrocyte invasion of the parasite. The gene encoding AMA-1 has been sequenced from populations of P. falciparum worldwide, but the haplotype diversity of the gene in P. falciparum populations in the Greater Mekong Subregion (GMS), including Thailand, remains to be characterized. In the present study, the AMA-1 gene was PCR amplified and sequenced from the genomic DNA of 65 P. falciparum isolates from 5 endemic areas in Thailand. The nearly full-length 1,848 nucleotide sequence of AMA-1 was subjected to molecular analyses, including nucleotide sequence diversity, haplotype diversity and deduced amino acid sequence diversity and neutrality tests. Phylogenetic analysis and pair-wise population differentiation ($F_{st}$ indices) were performed to infer the population structure. The analyses identified 60 single nucleotide polymorphic loci, predominately located in domain I of AMA-1. A total of 31 unique AMA-1 haplotypes were identified, which included 11 novel ones. The phylogenetic tree of the AMA-1 haplotypes revealed multiple clades of AMA-1, each of which contained parasites of multiple geographical origins, consistent with the $F_{st}$ indices indicating genetic homogeneity or gene flow among geographically distinct populations of P. falciparum in Thailand's borders with Myanmar, Laos and Cambodia. In summary, the study revealed novel haplotypes and population structure needed for the further advancement of AMA-1-based malaria vaccines in the GMS.