• Title/Summary/Keyword: Simultaneous Optimal Design

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Multi-response Optimization for Unfertilized Corn Silk Extraction Against Phytochemical Contents and Bio-activities

  • Lim, Ji Eun;Kim, Sun Lim;Kang, Hyeon Jung;Kim, Woo Kyoung;Kim, Myung Hwan
    • Food Engineering Progress
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    • v.21 no.3
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    • pp.256-266
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    • 2017
  • This study was designed to optimize ethanol extraction process of unfertilized corn silk (UCS) to maximize phytochemical contents and bioactivities. The response surface methodology (RSM) with central composite design (CCD) was employed to obtain the optimal extraction conditions. The influence of ethanol concentration, extraction temperature and extraction time on total polyphenol contents, total flavonoid contents, maysin contents, 2,2-diphenyl-1-picrylhydrazyl(DPPH) radical scavenging activities and tyrosinase inhibition were analyzed. For all dependable variables, the most significant factor was ethanol concentration followed by extraction temperature and extraction time. The following optimum conditions were determined by simultaneous optimization of several responses with the Derringer's desirability function using the numerical optimization function of the Design-Expert program: ethanol concentration 80.45%, extraction temperature $53.49^{\circ}C$, and extraction time 4.95 h. Under these conditions, the predicted values of total polyphenol contents, total flavonoid contents, maysin contents, DPPH radical scavenging activity and tyrosinase inhibition were $2758.74{\mu}g\;GAE/g$ dried sample, $1520.81{\mu}g\;QUE/g$ dried sample, 810.26 mg/100g dried sample, 56.86% and 43.49%, respectively, and the overall desirability (D) was 0.74.

Optimization of Mixture Composition to Improve Emulsifying Power and Solubilization of Sucrose Stearate (수크로스 스테아레이트의 유화력 및 가용화력 향상을 위한 혼합물 조성 최적화)

  • Jong Hwan Bae;Maria Song;Byung Suk Jin
    • Journal of the Korean Applied Science and Technology
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    • v.41 no.2
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    • pp.318-328
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    • 2024
  • In this study, we enhanced the emulsifying power and solubilization of sucrose stearate (SS) by creating mixtures with sodium deoxycholate (SDOC) and PEG-40 hydrogenated castor oil (HCO). We employed the design of mixture experiments (DOME) methodology to identify the optimal composition of the mixture, and the impact of varying the mixture composition on its characteristics was examined through regression analysis of the experimental data. It was revealed that the emulsifying power for coconut oil was most improved when only SDOC was added to SS, and solubilization was most improved when only HCO was added, while the emulsifying power for cetyl ethylhexanoate (CEH) was most significantly improved when SDOC and HCO were added together. As a result of simultaneous optimization of three characteristics, emulsifying power for each of coconut oil and CEH, and solubilization, the optimal surfactant mixture composition was determined as SS 0.7939, SDOC 0.0586, and HCO 0.1475.

Optimization of Detention Facilities by Using Multi-Objective Genetic Algorithms (다목적 유전자 알고리즘을 이용한 우수유출 저류지 최적화 방안)

  • Chung, Jae-Hak;Han, Kun-Yeun;Kim, Keuk-Soo
    • Journal of Korea Water Resources Association
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    • v.41 no.12
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    • pp.1211-1218
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    • 2008
  • This study is for design of the detention system distributed in a watershed by the Multi-Objective Genetic Algorithms(MOGAs). A new model is developed to determine optimal size and location of detention. The developed model has two primary interfaced components such as a rainfall runoff model to simulate water surface elevation(or flowrate) and MOGAs to get the optimal solution. The objective functions used in this model depend on the peak flow and storage of detention. With various constraints such as structural limitations, capacities of storage and operational targets. The developed model is applied at Gwanyang basin within Anyang watershed. The simulation results show the maximum outlet reduction is occurred at detention facilities located in upper reach of watershed in the peak discharge rates. It is also reviewed the simultaneous construction of an off-line detention and an on-line detention. The methodologies obtained from this study will be used to control the flood discharges and to reduce flood damage in urbanized watershed.

Resistive Superconducting Fault Current Limiters for Distribution systems using YBCO thin films (YBCO 박막을 이용한 배전급 저항형 초전도 한류기)

  • Lee, B.W.;Park, K.B.;Kang, J.S.;Kim, H.M.;Oh, I.S.;Shim, J.W.;Hyun, O.B.
    • Progress in Superconductivity
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    • v.7 no.2
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    • pp.114-119
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    • 2006
  • High critical current density, high n value, multiple faults endurances, and fast recovery characteristics of YBCO thin films are very attractive characteristics for developing resistive type superconducting fault current limiters. But due to the limited current and voltage ratings of one YBCO module, it is needed to construct series and parallel module connections for high capacity electric networks. Especially for distribution network, more than 30 units should be connected in series to meet voltage level. So in order to construct distribution-level superconducting fault current limiter, simultaneous quench in one YBCO thin films should be realized, and furthermore, quench should be occurred in all fault current limiting units equally to avoid local heating and failures. In this paper, we proposed optimum design of YBCO thin films for fault current limiting module and technical method using shunt resistor to achieve simultaneous quench between multi current limiting units. From the analytical and the experimental results, optimal current path and thickness of shunt material was determined for YBCO thin films and shunt resistor between modules was developed. Finally, 14 kV one phase resistive fault current limiter using multi YBCO thin films was constructed and it was possible to get satisfactory test results.

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Development of the Integrated Exhaust System and Techniques of Nitrogen and Condensate for Fuel Cell Electric Vehicle (연료전지 자동차용 질소/응축수 통합배출시스템 및 기술 개발)

  • Shim, Hyo Sub;Kim, Hyo Sub;Kim, Jae Hoon;Kwon, Bu Kil;Lee, Hyun Joon;Kim, Chi Myung;Park, Yong Sun
    • Transactions of the Korean hydrogen and new energy society
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    • v.25 no.5
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    • pp.516-524
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    • 2014
  • Proper discharge of nitrogen gas and water condensate is required in a conventional fuel cell system for performance, stability and durability of fuel cell stacks. Present study covers the development of integrated unit and its functioning logic for simultaneous nitrogen gas purge and water condensate drainage in a fuel cell vehicle system. Configuration of condensate drainage pipe, purge valve and level sensor is considered and optimized in physical integration. As a key factor, discharge time is considered and optimized based on the test result of constant-current operation with various operating temperature in logic development. Consequently, derived optimal values are applied and verified in actual vehicle drive mode test. Increase of system design flexibility, weight reduction and cost reduction are anticipated with this study. Additional study for physical and logical improvement is currently being implemented.

Collaborative optimization for ring-stiffened composite pressure hull of underwater vehicle based on lamination parameters

  • Li, Bin;Pang, Yong-jie;Cheng, Yan-xue;Zhu, Xiao-meng
    • International Journal of Naval Architecture and Ocean Engineering
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    • v.9 no.4
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    • pp.373-381
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    • 2017
  • A Collaborative Optimization (CO) methodology for ring-stiffened composite material pressure hull of underwater vehicle is proposed. Structural stability and material strength are both examined. Lamination parameters of laminated plates are introduced to improve the optimization efficiency. Approximation models are established based on the Ellipsoidal Basis Function (EBF) neural network to replace the finite element analysis in layout optimizers. On the basis of a two-level optimization, the simultaneous structure material collaborative optimization for the pressure vessel is implemented. The optimal configuration of metal liner and frames and composite material is obtained with the comprehensive consideration of structure and material performances. The weight of the composite pressure hull decreases by 30.3% after optimization and the validation is carried out. Collaborative optimization based on the lamination parameters can optimize the composite pressure hull effectively, as well as provide a solution for low efficiency and non-convergence of direct optimization with design variables.

Increase of the Voltage Rating of Resistive Type Superconducting Fault Current Limiter Using Equal Shunt Resistors (동일 병렬 저항을 이용한 초전도 저항형 한류소자 직렬연결방안 및 전압용량 증대)

  • 차상도;김혜림;심정욱;한용희;현옥배
    • The Transactions of the Korean Institute of Electrical Engineers B
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    • v.52 no.7
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    • pp.327-334
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    • 2003
  • We have investigated the quench behavior of the series connection of resistive type superconducting fault current limiter (SFCL) components based on YBCO films. Equal shunt resistors $R_s$ across individual SFCL components successfully produced simultaneous Quenches for 5 components in series, resulting in equal application of voltage to all components. If the two components having the highest and the lowest critical currents ($I_c$) quench safely, others quench altogether The highest shunt resistance is to guarantee the safe quenches of all components, leading to the equal voltage applications within the first half cycle after a fault in the short circuit test. The highest $R_s$ was found to be 28 [$\Omega$] for the components in the given quench environment. Considering the safe quenches and protection coordination, the optimal $R_s$ was suggested to be approximately a half of the highest $R_s$,, allowing wide selection of $R_s$ and $I_c$'s. This design provides a practical wav of connecting small SFCL components in series for high voltage application.

Multi-response optimization for milling AISI 304 Stainless steel using GRA and DFA

  • Naresh, N.;Rajasekhar, K.
    • Advances in materials Research
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    • v.5 no.2
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    • pp.67-80
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    • 2016
  • The objective of the present work is to optimize process parameters namely, cutting speed, feed rate, and depth of cut in milling of AISI 304 stainless steel. In this work, experiments were carried out as per the Taguchi experimental design and an $L_{27}$ orthogonal array was used to study the influence of various combinations of process parameters on surface roughness (Ra) and material removal rate (MRR). As a dynamic approach, the multiple response optimization was carried out using grey relational analysis (GRA) and desirability function analysis (DFA) for simultaneous evaluation. These two methods are considered in optimization, as both are multiple criteria evaluation and not much complicated. The optimum process parameters found to be cutting speed at 63 m/min, feed rate at 600 mm/min, and depth of cut at 0.8 mm. Analysis of variance (ANOVA) was employed to classify the significant parameters affecting the responses. The results indicate that depth of cut is the most significant parameter affecting multiple response characteristics of GFRP composites followed by feed rate and cutting speed. The experimental results for the optimal setting show that there is considerable improvement in the process.

Ultrasound-assisted Extraction for Development of Skin Whitening and Anti-wrinkling Cosmetic Materials from Spirulina platensis (스피루리나(Spirulina platensis)로부터 미백과 주름개선 생리활성 물질 분리를 위한 초음파 추출공정 개발)

  • Kim, So Hee;Jeon, Seong Jin;Kim, Jun Hee;Yeom, Suh Hee;Kim, Jin Woo
    • Korean Journal of Fisheries and Aquatic Sciences
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    • v.54 no.3
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    • pp.271-279
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    • 2021
  • Ultrasound-assisted extraction (UAE) conditions, including extraction time, extraction temperature, and ethanol concentration, were optimized to increase the total flavonoid content (TFC), tyrosinase inhibitory activity (TIA), and collagenase inhibitory activity (CIA) of Spirulina platensis through central composite design (CCD). For the optimization of the three dependent variables, a quadratic regression model was derived from 17 experimental sets for the simultaneous maximization of TFC, TIA, and CIA. The predicted optimal UAE conditions were 44.0 min of extraction time, 82.8℃ of extraction temperature, and 96.0% of ethanol concentration. Under these conditions, 0.93 mg QE/g DM of TFC, 81.9% of CIA, and 92.1% of TIA were predicted. The CCD-based UAE optimization enabled an increase in TFC, CIA, and TIA, thereby confirming that the S. platensis extract can be used in the development of a cosmetic material with skin whitening and anti-wrinkle effects.

Enhanced Lovastatin Production by Solid State Fermentation of Monascus ruber

  • Xu Bao-Jun;Wang Qi-Jun;Jia Xiao-Qin;Sung Chang-Keun
    • Biotechnology and Bioprocess Engineering:BBE
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    • v.10 no.1
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    • pp.78-84
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    • 2005
  • The purpose of this study was to optimize the solid state cultivation of Monascus ruber on sterile rice. A single-level-multiple-factor and a single-factor-multiple-level experimental design were employed to determine the optimal medium constituents and to optimize carbon and nitrogen source concentrations for lovastatin production. Simultaneous quantitative analyses of the ${\beta}$-hydroxyacid form and ${\beta}$-hydroxylactone for of lovastatin were performed by the high performance liquid chromatography (HPLC) method with a UV photodiode-array (PDA) detector. The total lovastatin yield ($4{\sim}6\;mg/g$, average of five repeats) was achieved by adding soybean powder, glycerol, sodium nitrate, and acetic acid at optimized levels after 14 days of fermentation. The maximal yield of lovastatin under the optimal composition of the medium increased by almost 2 times the yield observed prior to optimization. The experimental results also indicated that the ${\beta}$-hydroxylactone form of lovastatin (LFL) and the ${\beta}$-hydroxyacid form of lovastatin (AFL) simultaneously existed in solid state cultures of Monascus ruber. while the latter was the dominant form in the middle-late stage of continued fermentation. These results indicate that optimized culture conditions can be used for industrial production of lovastatin to obtain high yields.