• KSBB Journal
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• v.14 no.2
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• pp.212-219
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• 1999

lactic acid production from cellulose by simultaneous saccharification and fermentation(SSF) was studied. The SSF using cellulase enzyme Cytolase CL and Lactobacillus delbrueckii was strongly inhibited by the end product(lactic acid). An ion-exchange resin(RA-400) was used for in-situ product removal during SSF. The sorption capacity of the resin was 200mg/g-resin. The simple SSF and the extractive SSF resulted in lactic acid concentrations of 30.4g/L and 32.0g/L, respectively, at the initial substrate concentration of 50g/L. A model was developed to simulate the extractive SSF. The lactic acid conversion for the initial substrate of 100g/L was estimated to be improved from 60% to 09% by in-situ product removal. The experimentally determined kinectic parameters were pH dependent, and fitted as empirical expressions to establish their values at different pH's. Lactic acid productivity was predicted to be maximum at pH 4.5-5.0.

• Journal of the Korean Society of Groundwater Environment
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• v.6 no.2
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• pp.101-106
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• 1999

Open dump of refuse causes groundwater and soil contamination by leachate and air pollution by LFG(Landfill Gas). In this paper, in order to perform a study about reduction of high leachate and LFG collection & control, using a 3-D, 2-phase, transient FDM model, the analysis of simultaneous flow of leachate and LFG has been carried out. In present numerical analysis it is assumed that 58 percents of LFG will evaporate to the ambient air and the recharge rate of a landfill be 12 percent of the average precipitation per year. All other data were excerpted at the point of 1995 when three refuse layers had been buried. From numerical analysis we concluded that maximum head value is approximately 26 mH2O<-에이치투오 (2.52 atm) in the center of the system and that installing venting trench plays an important role in landfill stabilization. Evan with the assumption of three layers constructed and low recharge rate applied, it is found that cumulative leachate and LFG productions will be 15.1 million 세제곱미터, 5.58 billion 세제곱미터, respectively after 40 years.

• The Journal of Korean Medicine
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• v.32 no.3
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• pp.25-34
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• 2011

Objectives: We performed simultaneous determination of five constituents by HPLC in Samul-tang (SMT). Additionally, we investigated the immune-stimulatory potential of SMT on specific cellular and humoral immune responses in ovalbumin (OVA)-immunized mice. Methods: Reverse-phase chromatography using a Gemini C18 column operating at $40^{\circ}C$, and photodiode array (PDA) detection at 190-400 nm, were used for quantification of the five components of SMT. Mobile phase using a gradient flow consisted of two solvent systems. Solvent A was 1.0% (v/v) aqueous acetic acid and solvent B was acetonitrile with 1.0% (v/v) acetic acid. C57BL/6 mice were immunized intraperitoneally with OVA/alum ($100{\mu}g/200{\mu}g$) on days 1, 8, and 15. The extract of SMT (1000 mg/kg) was given to mice orally for 21 days (from day 1 to day 21). At day 22, OVA-, lipopolysaccharide (LPS)- and concanavalin A (Con A)-stimulated splenocyte proliferation and OVA-specific and total antibodies were measured in plasma. Results: Calibration curves were acquired with $r^2$>0.9999, and the relative standard deviation (RSD, %) for intra- and inter-day precision were both less than 3.5%. The recovery was in the range of 95.69-115.12%, with an RSD less than 6.0%. The contents of five components in SMT were 1.08-15.30 mg/g. SMT significantly enhanced Con A-induced splenocyte proliferation in OVA-immunized mice (p<0.01). Also, SMT significantly enhanced OVAspecific IgG, IgG1 and total IgM levels in plasma compared with the OVA-immunized group. Conclusions: The established method will be applied for the quantification of major components and immunestimulating activity in OVA-immunized mouse model of SMT.

• KSCE Journal of Civil and Environmental Engineering Research
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• v.31 no.5D
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• pp.671-677
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• 2011

A diversity of railway network function enhancement projects such as the double tracking, electrification, and direct operation have been actively executed to improve the railway service. When the new rapid transit is provided, how many people will use it instead of other transports? How will the railway choice behavior be changed? Accordingly, in this paper, the applicability of diverted travel demand forecast methods, by Revealed Preference(RP) and Stated Preference(SP) data was reviewed for Daegu metropolitan rail rapid transit service. As the result of combining RP and SP data, including the sequential and simultaneous approach, the total travel time and travel cost parameters are of the right sign and are highly significant. The simultaneous approach is more efficient in terms of the estimation of coefficients. In particular, methods to improve validity of the Mixed RP/SP models, when RP data is used proportionally, the diverted travel demand can be easily identified by railway fare and travel time service level. Therefore, it is considered that this will practically apply even in other regions as well as Daegu metropolitan railway.

• Journal of Technology Innovation
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• v.22 no.3
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• pp.261-286
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• 2014

Recently, project performance and management of government R&D program investing huge amount of budget is being focused. In this study, I built a model for estimating the performance creating paths of the government R&D program, then I analyzed the attributes of performances created by industries. I used simultaneous equations with FIML and examined the IT industry and CT industry of industrial technology innovation program using survey on R&D performance conducted by KEIT. On the analysis result, all the companies create the innovation performance through the government grants. However, the one who commercialize patents is SMEs in IT industry, and conglomerates in CT industry. SMEs in IT industry, which has characteristic of complex product, need extra self innovation activities even the government supports them. For improving the commercialization performance and technology development of SMEs in CT industry, it is effective when conducting cooperative research. These findings give us the implication that it is needed to consider different factors by industrial and enterprise characteristic when planning the public policy and government tasks.

• Journal of the Korean Chemical Society
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• v.47 no.1
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• pp.19-25
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• 2003

A spectrophotometric method for the simultaneous determination of anionic and nonionic surfactant based on the application of multivariate calibration method such as principal component regression(PCR) and partial least squares(PLS) has been studied. The calibration models in PCR and PLS were obtained from the spectral data in the range of 400~700 nm for each standard of a calibration set of 26 standards, each containing different amounts of two surfactants. The relative standard error of prediction(RSEP$_{\alpha}$) was obtained to assess the model goodness in quantifying each analyte in a 5 validation samples which containing different amounts of two surfactants.

• Transactions of the Korean Society of Mechanical Engineers B
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• v.38 no.12
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• pp.1051-1056
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• 2014

After hot rolling, a high-temperature steel plate with a temperature higher than $800^{\circ}C$ is rapidly cooled by multiple circular water jets. In this cooling process, because the temperature of the steel plate is much higher than the boiling point of the cooling water, film-boiling heat transfer occurs and a very thin steam layer forms between the plate surface and the cooling water. The steam layer acts as a thermal resistance that prevents heat transfer between the cooling water and the steel plate. In addition to the film-boiling heat transfer, complex physical phenomena such as the free-surface flow of residual water that accumulated on the material and the material's high-speed motion also occur in the cooling process. In this study, the simultaneous cooling process of the upper and lower sides of a running hot steel strip is investigated using a three-dimensional numerical model and the cooling performances and characteristics of the upper-side cooling and lower-side cooling are compared.

• Journal of Periodontal and Implant Science
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• v.52 no.2
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• pp.170-180
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• 2022

Purpose: This study was conducted to assess the effect of hard and/or soft tissue grafting on immediate implants in a preclinical model. Methods: In 5 mongrel dogs, the distal roots of P2 and P3 were extracted from the maxilla (4 sites in each animal), and immediate implant placement was performed. Each site was randomly assigned to 1 of the following 4 groups: i) gap filling with guided bone regeneration (the GBR group), ii) subepithelial connective tissue grafting (the SCTG group), iii) GBR and SCTG (the GBR/SCTG group), and iv) no further treatment (control). Non-submerged healing was provided for 4 months. Histological and histomorphometric analyses were performed. Results: Peri-implant tissue height and thickness favored the SCTG group (height of periimplant mucosa: 1.14 mm; tissue thickness at the implant shoulder and ±1 mm from the shoulder: 1.14 mm, 0.78 mm, and 1.57 mm, respectively; median value) over the other groups. Bone grafting was not effective at the level of the implant shoulder and on the coronal level of the shoulder. In addition, simultaneous soft and hard tissue augmentation (the GBR/SCTG group) led to a less favorable tissue contour compared to GBR or SCTG alone (height of periimplant mucosa: 3.06 mm; thickness of peri-implant mucosa at the implant shoulder and ±1 mm from the shoulder: 0.72 mm, 0.3 mm, and 1.09 mm, respectively). Conclusion: SCTG tended to have positive effects on the thickness and height of the periimplant mucosa in immediate implant placement. However, simultaneous soft and hard tissue augmentation might not allow a satisfactory tissue contour in cases where the relationship between implant position and neighboring bone housing is unfavorable.

• The Bulletin of The Korean Astronomical Society
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• v.46 no.2
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• pp.49.1-49.1
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• 2021

We carried out simultaneous monitoring observations of five maser lines, H₂O (22 GHz), SiO 𝝊 =1, 2, J =1-0 (43.1, 42.8 GHz), and SiO 𝝊 =1, J=2-1, J =3-2 (86.2, 129.3 GHz), toward the Mira variable star WX Serpentis with the 21-m antennas of the Korean VLBI Network (KVN) in 2009-2021 (~12 years). Most spectra of the H₂O maser are well separated into two parts of two blue- and one redshifted features within ± 10 km s-1 of the stellar velocity. All detected SiO masers are generally concentrated within ± 5 km s-1 of the stellar velocity, and sometimes appear split into two components. Overall, the profiles of SiO and H₂O masers detected in WX Serpentis illustrate typical characteristics of the Mira variable. In addition, flux variations of both SiO and H₂O masers are well correlated with the optical light curve of the central star, showing a phase lag of ~ 0.1 for SiO masers and ~ 0.2 for H₂O maser. This phenomenon is considered to be the direct effect of propagating shock waves generated by the stellar pulsation, because SiO and H₂O masers are sequentially distributed at different positions with respect to the central star. In addition, we analyzed long-term trends and characteristics of maser velocities, maser ratio, and the velocity extents (the full width at zero power; FWZP). We also investigated a spectral energy distribution (SED) ranging from 1.2 to 240 ㎛ obtained using several infrared data: 2MASS, WISE, IRAS, ISO, COBE DIBRE, RAFGL, and AKARI (IRC and FIS). From the IRAS LRS and ISO SWS spectra of this star, we identified 9.7 and 12 ㎛ silicate emission features consistent with the SE6 spectrum model, corresponding to the typical AGB phase.

• Korean Journal of Social Welfare Studies
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• v.41 no.1
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• pp.345-375
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• 2010

This study is aimed at investigating the effects of school violence on adolescent depression and suicide, where both the mediating effects of resilency and the gender diffences are considered. The data, collected from 664 high and middle school students, were examined by the statistics software SPSS 17.0 and AMOS 17.0, in which descriptive statistics, factor analysis, structural equation model analysis, and multi-group simultaneous analysis are utilized. As a result, it is shown from the structural equation modeling that school violence have positive effects on depression and suicide, but negative effects on family and academic resiliency. Both ego and family resiliency act as protective factors, negatively affecting the depression. In addition, the family resiliency had negative effects on suicide. The results of multi-group simultaneous analysis imply that school violence have different effects on suicide and family resiliency respectively, depending on gender differences. Female adolescents are affected more strongly than male adolescents.