• Asian Pacific Journal of Cancer Prevention
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• 제17권1호
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• pp.85-88
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• 2016

Background: Cervical cancer is the second most common malignancy among women worldwide, and women of reproductive age in Thailand. However, information on the behavior regarding cervical cancer in rural community Thailand is sparse. Objective: To assess the knowledge, attitude, and practice regarding cervical cancer (CC) among rural community women in Nakhon Ratchasima, Thailand, using predesigned structured questionnaires. Materials and Methods: A cross-sectional survey was conducted in 8 villages of Non Sung district, Nakhon Ratchasima province, Thailand, during January to April 2015. Bloom's taxonomy was used as a framework for the study. 265 women aged between 30-60 years old were selected by simple random sampling. All participants completed predesigned questionnaires with 4 parts: demographic data, knowledge, attitude, and practice regarding cervical cancer. Descriptive statistics were used for analysis in this study. Results: The majority of participants were in the age group of 41-50 years old (42.6%) with senior secondary school level of education (32.1%), marriage status (85.0%), agricultural employment (59.6%), and family income between 6,000-10,000 baht per month (54.3%). Some 63.4% and 68.7% participants had high knowledge and moderate level of attitudes regarding CC, while 41.1%, 48.7%, and 10.2% had neem regularly, irregularly or never screened for CC, respectively. The main reasons for not screening were were shyness (44.4%) and no time (55.6%). Vaginal discharge and itching were the common signs and symptoms of participants who were screened at a health promotion hospital of sub-district. Conclusions: CC is still a health problem in the rural community. Therefore, health education is required, particularly for those who have never undergone screening.

• 한국임상수의학회지
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• 제18권4호
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• pp.329-333
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• 2001

새로 개발되거나 혹은 기존의 어떤 진단검사를 다양한 임상상황에 적용하기 위해서는 먼저 이들 검사법의 진단적 정확도를 추정하는 연구가 반드시 선행되어야 한다. 진단의 정확도에 대한 추정치를 모른다면 검사결과를 해석하는 것이 불가능하기 때문이다. 특히 동일한 개체에서 감염부위별로 3개 이상의 시료를 얻어 진단검사를 적용하는 경우 각 시료의 검사결과는 독립적인 측정시료가 아니라 개체내에서 연관성이 매우 높은 종속적인 시료에 해당 한다. 즉 동일한 개체에서 얻은 시료일수록 검사결과에서 유사한 반응을 보이며 이 경우 분석의 단위는 각각의 개체가 아니라 검사부위가 되는데 이는 의학연구에서 매우 흔하다. 본 연구에서는 Helicobacter 균에 의한 감염을 검출하기 위하여 동일한 개로부터 위의 해부학적 구조상 pyloric antrum, body 및 cardia의 생검시료에 대하여 urease 검사와 PCR 검사를 적용하여 각 검사의 진단적 정확도를 추정하였다. urease 검사의 민감도와 특이도는 0.74 (95% 신뢰구간: 0.64-0.84)와 0.87 (95% 신뢰구간: 0.67-1.00)이었으며 PCR 검사의 민감도와 특이도는 0.95 (95% 신뢰구간: 0.89-1.00)와 0.90 (95% 신뢰구간: 0.70-1.00)로 두 검사의 특이도는 높은 것으로 나타났다. 그러나 PCR 검사에 비하여 urease 검사의 경우 가음성 (false negative)의 가능성이 높기 때문에 진단결과에 대한 신중한 해석이 요구된다.

• 환경생물
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• 제19권1호
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• pp.59-69
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• 2001

본 연구는 자연수중의 미생물을 식종원으로 하는 TOC-HANDAI법과 OECD 생분해법을 활용하여 자연수 환경내에서 환경호르몬물질인 비스페놀 A와 노닐페놀의 생분해성을 비교평가하였다. TOC-HANDAI법에 의한 BPA분해는 73-78% 이었고 OECD법은 이보다 다소 높은 77-81%를 나타내었다. 두 방법을 통한 BPA의 분해양상은 대체로 2단계를 거쳐 진행되었다. 즉 초기 1주일 이내에는 분해반응속도(k$_1$)가 0.24-0.34day$^{-1}$로 아주 빠르게 분해되었고, 그 후에는 아주 완만한 분해양상을 나타내었다(k$_2$는 0.02-0.05 $day^{-1}$). 이는 BPA가 자연수계에서 TOC로 약 20-25%가 중간생성물로 잔존하고 있음을 시사해 주고 있으며, 이 중간대사물이 완만한 분해과정에 기여하고 있다. 수계 환경에 따라 분해율이 현저하게 차이를 보이지만 노닐페놀은 20-48% 정도 밖에 분해되지 않는 난분해성 환경호르몬 물질임을 알 수 있다. 한편, 금강수계내 조사대상 하천과 대청호수의 조사지점에서 BPA는 모두 불검출되었다. 그러나 공단폐수 종말처리장 유입수에서 평균 25 ppb가 검출되었다.

• 한국음향학회지
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• 제24권4호
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• pp.230-237
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• 2005

수중음향 시스템에서는 이동 표적에 대한 상태 추정 및 표적 식별 등의 목적을 위해서 표적 방위 추적은 필수적이다. 그러나 감시영역에 근접 또는 교차 표적 등이 존재하는 다수 표적 상황에서의 방위 추적은 매우 어려운 문제로 다양한 접근방법으로 연구되어 왔다. SWORD는 배열 센서 신호의 출력 공분산 행렬로부터 방위 변위를 추정하여 표적을 추적함으로써 별도의 정보 연관 과정이 필요 없는 단순한 구조의 다중 표적 방위 추적 알고리즘을 제안하였으며, RYU 등은 표적 조향 벡터 (target steering vector)와 배열 센서 공분산 행렬의 신호 고유 벡터 (signal eigenvector)가 선형결합 관계임을 이용하여 교차 표적 (cross target)에 대해서도 우수한 성능을 나타내는 효율적인 알고리즘을 제안하였다. 또한 HWANG 등은 잡음 고유 벡터 (noise eigenvector)와 표적 조향 벡터가 직교 관계임을 이용하여 RYU의 알고리즘과 동일한 성능을 유지하면서 연산량을 개선한 알고리즘을 제안하였다. 그러나 기존의 방법은 코히어런트 (coherent) 다중 표적인 경우에는 추적 성능이 저하되는 단점이 있다. 본 논문에서는 배열 센서의 공분산 행렬로부터 추정할 수 있는 신호 고유 벡터와 잡음 공분산 행렬 (noise covariance matrix)의 특성을 이용하여 코히어런트 다중 표적에 대해 추적 성능을 유지할 수 있는 다중 표적 방위 추적 알고리즘을 제안하였으며, 근접 및 교차 기동하는 표적에 대한 시뮬레이션을 통하여 비코히어런트 (incoherent)와 코히어런트 다중 표적에 대해 추적 성능이 우수함을 확인하였다.

• 한국축산식품학회지
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• 제25권1호
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• pp.78-83
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• 2005

국내산 원유 및 우유의 향기성분을 보다 신속하고 간단하게 분석하기 위하여 Purge & Trap 및 GC-MS에 의하여 분석할 수 있는 조건에 대하여 연구를 수행하였다. Purge & Trap에 최대한 취할 수 있는 우유시료의 용량인 30 mL를 취하여 2시간 동안 헬륨가스로 purging하여 Tenax Trap에 흡착시켜 농축시킨 우유의 향기성분들을 탈착 후 GC-MS로 분석한 결과 우유의 향기성분들로 보고 된 주요 향기 성분들을 검출해 낼 수 있었다. 실험에 사용된 경상도 지역의 국내산 원유에서는 acetaldehyde, ethanol, 2-propanone(acetone), dimethyl sulfide, isobutanal, 3-methyl 2-butanone, 2-butanone, 3-methyl butanal, pentanal, 3-hydroxy-2-butanone, methyl disulfide, hexanal 및 2종의 미지 성분 등 총 14종의 휘발성 향기 성분이 검출되었다. 이 원유를 탈취하여 얻은 우유에서 acetaldehyde, 2-propanone, hexanal 및 미지 성분 92(M/sup +/) 의 4종은 탈취전의 우유와 비교하여 그 양에 변화가 없었으나, ethanol, dimethyl sulfide, pentanal, 3-hydroxy-2-butanone 및 methyl disulfide 등의 향기 성분 6종은 완전히 제거되어서 검출되지 않았다. 또한, 3-methyl 2-butanone, 2-butanone, 3-methyl butanal 및 미지성분 81(M/sup +/)의 4종은 그 양이 현저히 감소하였다.

• 대한치과기공학회지
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• 제18권1호
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• pp.73-94
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• 1996

This study was aimed for evaluating the validity of relative-productivity index on the basis of working hour(RPHW index) designed by author as new productivity index and drawing up a plan of bettering productivity to cope with financial difficulty of dental laboratories. Fortyeight dental laboratories extracted by cluster-sampling method form all the dental laboratories in Seoul were subjected for this study. And in each of them, the term of establishment which was divied into three group as short-term, mid-term and long-term group, the scale of dental laboratory which as divided into two group by number of dental technician as small-scale group and large-scale group, the salary system which was composed of salary criteria, pay according to ablility criteria and collectiveagree, the salary level, simple labor productivity index(SLP index), relative-productivity index on the basis of worker number(ROWN) and relative-productivity index on the basis of working hour(RPWH index) were surveyed through the self-administractive questionaires. The results as follows : Most of dental laboratories(93.6%) were managed by non-professional managers. The establishment rate per year of dental laboratory was the increase. The mean number of employees of dental laboratories was $7.00{\pm}3.90$ person. The ratio of smallscale group(under the 5 employees) was 42.6% and as the term of establishment was shorter, the ratio of small-scale group was higher. The mean establishment area of dental laboratories was $24.49{\pm}10.97$ unit and the mean establishment area per head of dental laboratories was $4.05{\pm}3.90$ unit. The estabilshment area and area per head were not significantly associted with the term of establishment, but as the term of establishment was shorter, the estabkishment area per head was slightly wider. The establishment area per head in small-scale group was significantly wider than large-scale group(over the 6 emplayees) The salary criteria(54.4%), pay according to ability(79.2)m ability criteria(77.1%) and collectiveagree(79.2%) as salary systems were used in the most of all dnetal laboratoies. The all salary systems were not significantly associated with the term of establishment and the scale of dental laboratories. The monthly mean salary level of dental laboratoies was $125.64{\pm}31.06$ milion won. The monthly salary level was not significantly associated with the term of establishment and the scale of dental laboratores. But the monthly salary level in the short-term group and the small-scale group were slightly lower than others. The SLP index, the RPWN index and the RPWH index of dental laboratories were $132.16{\pm}48.41$, $382.41{\pm}128.76$ and $76.06{\pm}25.11$, respectively. The SLP, the RPWN and the RPWH of dental laboratories were not significantly associated with the term SLP, the RPWN and the RPWH of dental laboratories were significantly associated with the area of dental laboratory and the salary level. Except for only the association salary criteria among salary system with RPWH of dental laboratories, all other salary system were not associated with the SLP, the RPWN and the RPWH of dental laboratories.

• Child Health Nursing Research
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• 제7권1호
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• pp.35-50
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• 2001

The ability of neonates to perceive and react to pain, has been acknowledged recently. Recent researches have been shown that even short term pain can have lasting negative effects. We know that most of the anatomical pathway and neurotrans-mitter function necessary for pain perception are fully or nearly fully developed in the neonatal period. Many people are still reluctant to believe that pain felt by neonates may be as severe as that felt by older children or adults yet. The objective of the study is to assess and compare the analgesic effects of orally administered sucrose and pacifiers. And to determine the synergistic analgesic effects of sucrose and pacifiers. The tools for this study is Lawrence's NIPS (neonatal infant pain scale) with behavioural pain responses and index for pain physiological reponses as heart rate, respiratory rate and degree of SaO₂. The participants are 96 healthy infants of neonatal age 1-7days and randomised to receive heel prick before 2minutes to blood sampling and physiological test in Nursery of K Medical University Hospital on May-July, 2000. The experimental group assigned to one of three treatment groups : no treatment; a pacifier; placebo(2ml 25％ sucrose). Collected data were analyzed with the SAS program using X²-test, ANOVA and Duncan's multiple range test as post hoc. The results were as follows. 1) Pain behaviour responses: The pain score of placebo group(2ml 25％ sucrose) is lower than no treatment group and pacifier group significantly(P=.000). Placebo group is different from no treatment and pacifier group with Duncan's multiple range test. 2) Pain physiologic responses (1) heart rate: The heart rate of placebo group(2ml 25％ sucrose) is different from that of no treatment group and pacifier group significantly(P=.000). The heart rate change of placebo group is less than the other groups. (2) respiratory rate: The respiratory rate of placebo group(2ml 25％ sucrose) is different from that of no treatment group and pacifier group insignificantly (P=.2340). But, the respiratory rate of placebo group is lower than the other groups. (3) SaO₂: The SaO₂ score of placebo group(2ml 25％ sucrose) is different from that of no treatment group and pacifier group insignificantly (P=.3265). But, the change of SaO₂ score of placebo group is less than the other groups. In conclusion, the sucrose placebo showed pain relief effect in behavior responses and less physiological responses. Accordingly, the sucrose placebo should be applied nursing intervention for simple pain management as heel prick.

• 한국산학기술학회논문지
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• 제17권1호
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• pp.664-675
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• 2016

본 연구의 목적은 간호사의 시간선택제 근무에 대한 인식을 조사하고 활성화를 위한 합리적인 근무방안을 제시하는 것이다. 자료는 무작위 할당표출법을 이용하여 전국의 532명의 간호사를 대상으로 2015년 2월 10일부터 24일 까지 설문조사를 하였다. 자료 분석을 위해 SPSS 21.0 프로그램을 사용하였다. 본 연구의 결과에서 시간선택제 근무 중 단축시간제에 대한 필요성($M=3.89{\pm}0.87$)과 지원 의향(46.2%)이 가장 높게 나타났으며, 야간전담제, 휴일전담제, 2교대제 순이었다. 지원 선택의 이유로는 교대근무의 힘든 업무와 육아 병행의 어려움이 가장 높게 나타났다. 시간선택제 근무시행에 따른 긍정적인 영향으로는 자기계발 활동이나 여가활동의 증가로 삶의 질을 높일 수 있고, 육아와 일-가정 양립이 가능한 점이었으며, 부정적인 영향으로는 비정규직으로 채용될 우려와 급여가 감소할 것이라는 의견이 가장 높게 나타났다. 본 연구의 결과를 토대로 시간선택제 근무를 시행하기 위한 선결조건으로 시간선택제 근무 유형에 따른 보상과 근무조건에 대한 표준화된 운영 지침을 제시함으로써 추후에 시간선택제 간호사의 균등한 근무조건을 마련하는데 기여할 수 있다.

• 한국육종학회지
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• 제41권4호
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• pp.369-376
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• 2009

Cowpea might have been introduced from China to Korea and cultivated for several hundred years but it has never been a staple food crop in Korea. In this study, genetic diversity of 492 Korean cowpea landrace accessions that have passport information was estimated using six SSR markers. The mean of Weir's gene diversity was 0.665 from all accessions investigated in the study. Cowpea gene diversity of six local provinces in Korea was ranged from 0.370 in accessions of Gangwon to 0.680 in Jeonra provinces. Low gene diversity of the cowpea genepool of Gangwon province was probably derived from relatively few introductions. Especially SSR markers VM36 and VM39 seem to be good markers to distinguish the Gangwon accessions from others by occurring at a specific locus with higher than 78% of allele frequency. Except for the Gangwon province with the low genetic diversity, gene diversity of cowpea accessions from other provinces was ranged from 0.600 to 0.680 indicating no big differences among provinces. Distribution pattern of the allele frequencies was similar among the other provinces. This may reveal that Korean farmers might exchange cowpea seeds easily with even their neighbors with geographical barriers. A core collection, 100 landraces, ca. 20% of base collection, was developed at the 70% of a similarity coefficient level using random sampling approaches after stratification of the entire landrace collection based on the phenetic dendrogram. The variability of SSR in the base and core collections of Korean cowpea landrace was compared by calculating Weir's gene diversity. The mean of Weir's gene diversity of the core was 0.707 while that of the base collection was 0.665. The higher diversity index in the core collection indicates that it maintains the initial variability and well represents the base collection. The core collection included one of determinate accession (IT 216155) and two of no branching type accessions (IT 103959 and IT 161024). The core collection could be used to guide more efficient management and utilization of the entire collection. This core collection should be revised periodically as additional accessions are collected and further characterization is conducted.

• Journal of the Korean Association of Oral and Maxillofacial Surgeons
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• 제47권5호
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• pp.373-381
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• 2021

Objectives: In the present study, the effects of sagittal split ramus osteotomy (SSRO) combined with intraoral vertical ramus osteotomy (IVRO) for the treatment of asymmetric mandible in class III malocclusion patients were assessed and the postoperative stability of the mandibular condyle and the symptoms of temporomandibular joint disorder (TMD) evaluated. Materials and Methods: A total of 82 patients who underwent orthognathic surgery for the treatment of facial asymmetry or mandibular asymmetry at the Department of Oral and Maxillofacial Surgery, Dong-A University Hospital, from 2016 to 2021 were selected. The patients that underwent SSRO with IVRO were assigned to Group I (n=8) and patients that received bilateral SSRO (BSSRO) to Group II (n=10, simple random sampling). Preoperative and postoperative three-dimensional computed tomography (CT) axial images obtained for each group were superimposed. The condylar position changes and degree of rotation on the superimposed images were measured, and the changes in condyle based on the amount of chin movement for each surgical method were statistically analyzed. Results: Group I showed a greater amount of postoperative chin movement. For the amount of mediolateral condylar displacement on the deviated side, Groups I and II showed an average lateral displacement of 0.07 mm and 1.62 mm, respectively, and statistically significantly correlated with the amount of chin movement (P=0.004). Most of the TMD symptoms in Group I patients who underwent SSRO with IVRO showed improvement. Conclusion: When a large amount of mandibular rotation is required to match the menton to the midline of the face, IVRO on the deviated side is considered a technique to prevent condylar torque. In the present study, worsening of TMD symptoms did not occur after orthognathic surgery in any of the 18 patients.