• Asian Pacific Journal of Cancer Prevention
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• 제14권6호
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• pp.3831-3836
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• 2013

Background: S100A14 has recently been implicated in the progress of several types of cancers. This study aimed to investigate the clinical significance and possible mechanisms of action of S100A14 in the invasion and metastasis of hepatocellular carcinoma (HCC). Methods: S100A14 expression in HCC was detected at mRNA and protein levels and its prognostic significance was assessed. Functional roles of S100A14 in HCC were investigated using MTT, BrdU, wound healing, transwell invasion assay and HCC metastatic mouse model. Results: S100A14 was significantly elevated in HCC tissues, correlated with multiple tumor nodes, high Edmondson-Steiner grade and vascular invasion. Multivariate Cox analysis showed that the S100A14 expression level was a significant and independent prognostic factor for overall survival (OS) of HCC patients (hazard ratio=1.98, 95% confidence interval=1.14-3.46, P=0.013). S100A14 promoted cell proliferation, invasion and metastasis of HCC in vitro and in vivo. Conclusion: These results suggest S100A14 is a novel prognostic marker and therapeutic target for HCC.

• The Journal of Korean Physical Therapy
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• 제30권4호
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• pp.117-122
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• 2018

Purpose: The objective of this study was to examine the effect of vibration exercises generated from an $XCO^{(R)}$ trainer on supraspinatus, infraspinatus, teres minor, and deltoid muscle thickness. Methods: Thirty subjects were evenly divided into two groups. Muscle thickness was measured by a sonogram prior to the study, and at three and six weeks after the intervention. Changes in muscle thickness were analyzed using a repeated measure analysis of variance (ANOVA). The significance level for the statistical test was set at ${\alpha}=0.05$. Results: A statistically significant differences in timing, interactions between timing and the groups, and between-group changes were demonstrated for supraspinatus muscle thickness (p<0.05). A similar finding was reported for infraspinatus, teres minor, and deltoid muscles with regard to the interactions between timing and the groups (p<0.05), although the between-group change did not reach statistical significance (p>0.05). Conclusion: Significant changes were observed in the thickness of the supraspinatus, infraspinatus, teres minor, and deltoid muscles, owing to the use of vibration exercises generated from an $XCO^{(R)}$ trainer. These findings can be used as a foundation for future studies on rehabilitation training.

• 전자공학회논문지 IE
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• 제43권1호
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• pp.52-58
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• 2006

본 논문에서는 제한된 자원을 가지는 포터블 임베디드 시스템을 위하여, 작은 메모리 사용으로 효율적으로 영상 부호화가 가능한 웨이블릿 영상 부호화기를 제안하였다. 제안된 방법은 부호화 과정시 요구되는 메모리 사용량을 줄이기 위해 웨이블릿 계수들의 비트 레벨 정보를 가지는 2차원 중요 계수 배열을 사용한다. 제안된 방법은 중요 계수에 대한 부호화 과정과 계수들의 비트 레벨 정보의 부호화 과정을 한 번에 수행할 수 있다. 실험 결과 기존의 부호화 방법보다 화질 면에서 비슷하거나 우수한 성능을 보였으며, 2차원 중요 계수 배열을 이용한 최소의 메모리 사용으로 다양한 비트율에서 영상의 일그러짐 없이 안정적으로 동작함을 확인하였다.

• 대한방사선기술학회지:방사선기술과학
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• 제11권1호
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• pp.25-31
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• 1988

Studies on the clinical significance with Amerlex $FT_{4}$ RIA kit observing the determination of $FT_{4}$ were investigated using a tracer as $^{125}I-T_{4}$ derivative which is not almostly bound to thyroxine binding globulin, etc. The results are followed; 1. $FT_{4}$ value($1,55{\pm}0.38ng/100ml$) of normal group was not accorded that of hyperthyroidism with Amerlex $FT_{4}$ RIA kit, and was higher than that of hypothyroidism. 2. $FT_{4}$ value was lower level in chronic-kidney disfunction syndrome whereas, it was normal in a cancer patient, a woman in pregnancy and a patient in TBG disfunction. 3. The value of this method is a good corelationship at that of equilibrium dialysis method. (r=0.931) 4. $FT_{4}$ value by this kit was linear relationship to those of the other kit (Gamma Coat and Liquisol), and the normal value of each methods was also similar. As mentioned above, this method is more simple and rapid, compared to the other method. Therefore, it was thought that this method is a very useful clinically.

• 한국전문물리치료학회지
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• 제6권1호
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• pp.35-46
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• 1999

The purposes of this study were to evaluate and compare the limits of stability(LOS) at different body positioning(standing and one leg standing) in normal 20 years of age. Fourty subjects participated in the study. Subjects comprised 20 males and 20 females who without neurologic, orthopaedic impairments and balance performance impaired. The LOS was measured at Two Feet Forceplate and One Leg Forceplate with BPM(Balance Performance Monitor) Dataprint Software Version 5.3. The subjects stood 4 inches between the feet at Two Feet Forceplate and stood one legged at One Leg Forceplate. In this study applied the paired t-test and independent t-test to determine the statistical significance of results at 0.01 and 0.05 level of significance. The results of this study were as follows: 1) The anteroposterior LOS significantly increased with one legged stance(p<0.05). 2) The mediolateral LOS significantly decreased with one legged stance(p<0.01). 3) There were significant difference posterior LOS in standing and anterior LOS in one legged stance according to sexual difference(p<0.05). 4) The mediolateral LOS was not significant difference between standing and one legged stance according to sexual difference(p>0.05).

• 보건교육건강증진학회지
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• 제21권1호
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• pp.319-328
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• 2004

The purpose of this study was to examine the relation between thoracic scoliosis and gastroenteric disorder. In this article, We surveyed sixty two patients and investigated through a questionnaire the health and meal habits, digestive trouble levels, stress levels(BEPSI-K), and the stress response index(SRI). Participants were classified according to each group in over $10^{\circ}$(vertebral scoliosis), under $10^{\circ}$(functional scoliosis) and made a diagnosis of X-ray of scoliosis grade. The data was took statistics on two group by independent t-test, chi-square test with SPSS/PC+ 10.0 program. The statistically significance was a p＜.05 and the following results were obtained； 1. In general characteristics, The thoracic scoliosis was as many as women, weight 50∼60kg, height 160∼170cm, married person. 2. Relations between health and meal habit with thoracic scoliosis was not statistically significant(p＞.05). 3. Relations between thoracic scoliosis and digestive trouble level was statistically significance (p＜.05). 4. Relations between thoracic scoliosis and incidence rate of internal disease was statistically significant(p＜.05). 5. Relations between thoracic scoliosis and stress(BEPSI-K) was statistically significant(p＜.05). 6. Relations between thoracic scoliosis and stress(SRI) was statistically significant(p＜.05). These results lead us to the conclusion that thoracic scoliosis influences digestive trouble, incidence rate of internal disease and stress. However, there results are not easy to explain because of the limitations of a few subjects and a single comparison. Therefore, further research on this study thoroughgoing inspection would clarify the association of thoracic scoliosis and gastroenteric disorders.

• 응용통계연구
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• 제19권3호
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• pp.565-578
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• 2006

의약학 분야에서는 두 집단에서 하나의 반복요인을 가지는 반복측정 자료가 많이 사용된다. 이 논문에서는 반복측정된 자료에서 두 군의 시간에 따른 반응값의 선형추세를 비교하여 두 집단간의 차이를 검정하는 방법을 제안한다. 각 개체에서 회귀계수를 추정하고 추정된 회귀계수들에 의해 생성된 표본을 가지고 이표본 t검정(unpaired t-test), 윌콕슨 순위합 검정(Wilcoxon rank sum test), 위치검정(placement test)으로 두 집단간 기울기의 차이를 검정한다. 모의실험(Monte Carlo Simulation)을 통해 실험유의수준(experimental significance level)과 검정력 (power)을 비교하였다.

• 응용통계연구
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• 제22권1호
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• pp.115-127
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• 2009

The purpose of statistical analyses of array-CGH experiment data is to divide the whole genome into regions of equal copy number, to quantify the copy number in each region and finally to evaluate its significance of being different from two. Several statistical procedures have been proposed which include the circular binary segmentation, and a Gaussian based local regression for detecting break points (GLAD) by estimating a piecewise constant function. We propose in this note a penalized spline regression and its simultaneous confidence band(SCB) approach to evaluate the statistical significance of regions of genetic gain/loss. The region of which the simultaneous confidence band stays above 0 or below 0 can be considered as a region of genetic gain or loss. We compare the performance of the SCB procedure with GLAD and hidden Markov model approaches through a simulation study in which the data were generated from AR(1) and AR(2) models to reflect spatial dependence of the array-CGH data in addition to the independence model. We found that the SCB method is more sensitive in detecting the low level copy number alterations.

• 한국학교ㆍ지역보건교육학회지
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• 제20권3호
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• pp.43-52
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• 2019

Objectives: This study aims to understand the effects of job stress and emotional labor on perceptive health status of dental hygienist's. And provide basic data by for establishing the plan for the effective management of job stress and emotional labor and the promotion of health. Methods: Self-evaluation questionnaires were surveyed for 441 dental hygienist's who agreed to participate in the survey, using questionnaires used in the preceding study were modified and complemented. We analyzed the data with frequency analysis, descriptive statistics, t-test, chi-square test와 ANOVA, Spearman correlation coefficient by using IBM SPSS Statistics 21.0 (IBM Co., Armonk, NY, USA). The significance level for significance was set at 0.05. Results: health status were job stress, emotional labor significant negative correlation. The factors having significant effects on health problem were physical health status, the job culture of job stress, lack of job autonomy, organizational instability, and workplace culture. In addition, social health status was affected by emotional expressionism, relationship conflict, organizational instability, organizational system, and workplace culture. Conclusion: Recognizing the importance of the management of job stress and emotional labor in the working environment to dental clinic and hospital managers and managerial dental hygienists, a dental hygienist health promotion intervention program is needed to mitigate and cope with job stress and emotional labor.

• 대한물리치료과학회지
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• 제3권3호
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• pp.15-23
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• 1996

The purpose of this study to evaluate and compare the proprioception of the dominant knee joint at different conditions in normal 20 years of age. The pripriocption was measured at sitting, supine, prone position with the eyes opened and the eyes closed. All were assessed with and without a knee brace around the knee by reproduction the position to which a joint has previously been placed. In this study, 24 rehabilitation therapy major students were assessed at Hansoe University. In this study applied the paired t-test and 1-way ANOVA to determine the statistical significance of results at 0.05 level of significance. The error average of proprioception was $4.65{\pm}2.95^{\circ}$ with the eyes closed and $4.08{\pm}1.14^{\circ}$ with the eyes opened in sitting position, $5.56{\pm}3.18^{\circ}$ with the eyes closed and $4.98{\pm}2.99^{\circ}$ with the eyes opened in supine position and $5.60{\pm}1.64^{\circ}$ with the eyes closed and $4.87{\pm}2.16^{\circ}$ with the eyes opened in prone position. There was no significantly difference the error average between the eyes opened group and the eyes closed group. There was no significantly difference the error average among the three positions. The error average decreased significantly in knee brace group at all conditions.