• Journal of Chest Surgery
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• v.10 no.2
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• pp.195-204
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• 1977

Dynamic lung compliance was measured in healthy ten young[mean age, 26 years] male and five young[mean age, 25 years] female. Lung volume was integrated of the rate of flow signal which was obtained by using pneumotachograph and differential pressure transducer[PM 5, Statham]. Intrapleural pressure was measured as that of intraesophagel pressure. Esophageal ballon, 15. 5cm in length, 4ml of luminal capacity and made of thin latex, was connected to the polyethylene tube that had 12-14 side holes and was of 1.5mm of ID. Transpulmonary pressure was traced by means of differential pressure transducer[PM 131, Statham] to which connected the esophageal balloon catheter and connection tube from mouth piece. Lung volume and transpulmonary pressure were photographed by cathode ray oscilloscope camera while the subjects were breathing spontaneously. Dynamic lung compliance loop was displayed on single trace monitor and subtraction was performed for the quasi-static hysteresis. Dynamic lung compliance was measured, 1. by plotting the pressure-volume relationship 2. from the subtracted pressure-volume loop. Results were as follows. 1. Dynamic lung compliances measured by plotting of healthy young male and female were $0.202{\pm}0.06$ and $0.190{\pm}0.023L/cm$ $H_2O$ respectively. 2. When measured from subtraction loop, dynamic lung compliance for male and female were $0.327{\pm}0.107$, and $0.27{\pm}0.06L/cm$ $H_2O$ respectively. 3. Dynamic chest wall and total respiratory system compliance were also measured. 4. Dynamic lung compliance by plotting appeared to be essentially same when compared to that of static compliance reported previously from our laboratory, however, that obtained from subtraction loop revealed higher values than the compliances obtained by plotting and that of static compliance.

• Transactions on Electrical and Electronic Materials
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• v.12 no.2
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• pp.56-59
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• 2011

The characterization of the chemical mechanical polishing (CMP) process for undensified phophosilicate glass (PSG) film is reported using design of experiments (DOE). DOE has been used by experimenters to understand the relationship between the input variables and responses of interest in a simple and efficient way, and it typically is beneficial for determining the appropriatesize of experiments with multiple process variables and making statistical inferences for the responses of interest. The equipment controllable parameters used to operate the machine consist of the down force of the wafer carrier, pressure on the back side wafer, table and spindle speeds (SS), slurry flow (SF) rate, pad condition, etc. None of these are independent ofeach other and, thus, the interaction between the parameters also needs to be understoodfor improved process characterization in CMP. In this study, we selected the five controllable equipment parameters the most recommendedby process engineers, viz. the down force (DF), back pressure (BP), table speed (TS), SS, and SF, for the characterization of the CMP process with respect to the material removal rate and film uniformity in percentage terms. The polished material is undensified PSG which is widely used for the plananization of multi-layered metal interconnects. By statistical modeling and the analysis of the metrology data acquired from a series of $2^{5-1}$ fractional factorial designs with two center points, we showed that the DF, BP and TS have the greatest effect on both the removal rate and film uniformity, as expected. It is revealed that the film uniformity of the polished PSG film contains two and three-way interactions. Therefore, one can easily infer that process control based on a better understanding of the process is the key to success in current semiconductor manufacturing, in which the size of the wafer is approaching 300 mm and is scheduled to continuously increase up to 450 mm in or slightly after 2012.

• Clinical and Experimental Pediatrics
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• v.52 no.12
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• pp.1388-1391
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• 2009

Poland syndrome is characterized by unilateral absence or hypoplasia of the pectoralis muscle and variable degree of ipsilateral hand anomalies. Mobius syndrome is a congenital neurological disorder characterized by complete or partial facial paralysis. Although the pathogeneses of these diseases are not well-characterized, diminished blood flow to the affected side is thought to play a role. A male infant weighing 2.670 g was born at 38+3 weeks of gestation with left facial paralysis, left chest wall defect with dextrocardia, and symbrachydactyly between the second and third fingers. The combination of Poland-Mobius syndrome is rare, and only 2 cases associated with dextrocardia have been reported worldwide. Here, we report the first case of Poland-Mobius syndrome associated with dextrocardia in Korea.

• Korean Institute of Interior Design Journal
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• v.26 no.2
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• pp.101-109
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• 2017

The food and beverage spaces of modern industrial society have transformed from a simple space for meals into a space of culture, communication and experience as society becomes more complex and diverse along side economic growth. An interior designer who is rapidly rising on this flow of change is Yukio Hashimoto. While working for interior design firm Super Potato, which highlights food and beverage spaces, he was much affected by the expression methods of representative designer Takashi Sugimoto, who makes use of natural elements. By using these expression methods that make use of natural elements in his own creation of spatial ambience and elements of experience and by adding his own differentiated expression methods, he emphasizes an effective spatial expression for food and beverage spaces. The design characteristics of Yukio Hashimoto's food and beverage spaces are as follows. First natural elements like light and water are recreated as memories of nature after being established through a methodology that allows these elements to penetrate his own thoughts. Second, he pursues a hybrid design through the harmony between past tradition and current expressive techniques. Third, he expresses objets of light through a formative sense of shape expressed with light.. Fourth, he establishes an axis in the interior space by light and structure and endows a strong directionality that induces symmetric characteristics, gaze, and movement.. Fifth, he installs lights at the bottom of weighty materials and expresses a sense of floating by light. Sixth, he uses an illusion technique that makes use of the ambiguity and depth of space resulting from reflecting materials like mirrors. The study hopes that such design expression characteristics of food and beverage spaces can be used as data for interior designers to apply and develop a new design vocabulary.

• Journal of the Korean Society of Environmental Restoration Technology
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• v.9 no.2
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• pp.45-58
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• 2006

This study was aimed to propose the plan of creating a biotope reflecting an ecological education as well as its function as the habitats of amphibian in Namsan Urban Natural Park in Seoul. There were Cheonil mineral spring area which was located on the southern side of Namsan, wetlands which was already created on the east valley(800$m^2$) and a buffer area of the circumference(1,100$m^2$) as the biotope sites. Major fields of this study include a survey of the staus, a basic plan, a master plan; a survey of this site was focused on topography, water system, existing vegetation, wildbird, amphibian, trail; a detailed plan was focused on flow plan, planting plan, facility plan. Existing vegetation was classified into 8 types; Pinus densiflora forest, Pinus densiflora planted area, Prunus sargentii-Quercus spp. forest, Pinus rigida forest, Robinia pseudoacacia forest, artificial green space, wetlands, south beltway. There were Pinus densiflora planted area and Prunus sargentii-Quercus spp. forest as major vegetations of this site. 14 species and 33 individuals of wildbirds appeared, Rana temporaria ornativentris and Hynobius leechi were investigated in the wetlands.In particular, habitats of amphibian were divided eco-zone, buffer-zone and restore-zone, and habitats and facilities which would be suitable for the characteristics of each space were planned. As a result, environment elements of good habitats including spawn wetlands of amphibian, harbor of amphibian, water plant of wetland, wild shrubs forest, ecological landscape forest, wetland observation trail, fence of wetland protection and ramp by pebble and log were created at the site. The amphibian biotope of Namsan is rated high as an important space for conserving biodiversity. Accordingly, continuous monitoring of this biotope as a urban habitat is required as the environment changes.

• Transactions of the Korean Society of Mechanical Engineers A
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• v.21 no.11
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• pp.1773-1785
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• 1997

The cooling stage is the very critical and most time consuming stage of the injection molding process, thus it cleary affects both the productivity and the part quality. Even through there are several commercialized package programs available in the injection molding industry to analyze the cooling performance of the injection molding coling stage, optimization of the cooling system has npt yet been accomplished in the literature due to the difficulty in the sensitivity analysis. However, it would be greatly desirable for the mold cooling system designers to have a computer aided design system for the cooling stage. With this in mind, the present study has successfully developed an interated computer aided design system for the injection molding cooling system. The CAD system utilizes the sensitivity analysis via a Boundary Element Method, which we recently developed, and the well-known CONMIN alforuthm as an optimization technique to minimize a weighted combination (objective function) of the temperature non-uniformity over the part surface and the cooling time related to the productivity with side constranits for the design reality. In the proposed objective function , the weighting parameter between the temperature non-uniiformity abd the cooling time can be adjusted according to user's interest. In this cooling system optimization, various design variable are considered as follows : (i) (design variables related to processing conditions) inlet coolant bulk temperature and volumetric flow rate of each cooling channel, and (ii) (design variables related to mold cooling system design) radius and location of each cooling channel. For this optimum design problem, three different radius and location of each cooling channel. For this optimum design problem, three different strategies are suffested based upon the nature of design variables. Three sample problems were successfully solved to demonstrated the efficiency and the usefulness of the CAD system.

• Korean Institute of Interior Design Journal
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• no.26
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• pp.26-34
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• 2001

The problems with the small exhibition buildings such a small gallery and art center recently constructed did not make the characteristics of the place specifying and did not form a big flow in the line of urban connection. Also it was deficient in the image like a cultural space because of the commercial aspects of the individual buildings. According to this view, this study is to evaluate the exteriors of the small exhibition buildings that the public prefers on the psychological side as a design theory and then, it is to present the direction of desirable form constitution hereafter. In the design of the small exhibition buildings exterior that the public must prefers, the principles and techniques of constitution that operate are the most initiative as follows. As for the principles of unity in the constitution of the small exhibition buildings exterior that the public prefers, Eigen Value is 7.573 and the explanatory force takes 21.637% at the top and it plays a leading role. In the comparison of the appearance, it shows that it is a factor with the largest specific gravity. The next factors were grouped in good order: the balance, ornamental technique, change, shipping technique, rhythm, harmony, symbolic technique, area technique and adding technique. As a result, in the design of the small exhibition buildings exterior, the architects have to constitute the principles of balance, change, rhythm and harmony by most of the unity and the symbolic technique and form technique by most of the ornamental techniques harmoniously and have to give Identity like exhibition buildings.

• Magazine of the Korean Society of Agricultural Engineers
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• v.12 no.3
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• pp.2003-2012
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• 1970

In order to the influence of grain size distribution on compressive strength and coefficient of permeability, unconfined compression test and permeability test were performed for seventy samples that have various grain-size distributions. Its results are as follows: 1. Maximum unconfined compressive strength appears at the dry side of optimum moisture content. 2. Unconfined compressive strength is proportional to the increase of percent passing of No. 200 sieve. 3. Precent of deformation in failure increases in proportion to the increase of percent passing of No. 200 sieve, and modulus of No. 200 sieve, and modulus of deformation also increases in proportion to percent passing of No. 200 sieve. 4. Unconfined compressive strength increases in proportion to uniformity coefficient, liquid limit and plastic index, but it decreases gradually according to the increase of coefficient of grading and classification area. 5. Maximum dry density decreases according to the increase of void ratio. 6. Coefficient of permeability decreases according to the increase of percent passing of No. 200 sieve, and when percent of No. 200 sieve, and when percent passing of No. 200 enlarged more than 40%, it becomes less than $10^{-6}cm/sec$ which is the limit of coefficient of permeability of core material for earth dam proposed by Lee. 7. Coefficient of permeability increases according to the increase of coefficient of grading, classification area and index of Talbot formula r, but it was rather decrease by the increase of uniformity coefficient. 8. Coefficient of permeability seems to depend on the size and the shape of the flow path which is a series of void to be concerned by the size and the proprton of soil grain, even though void ratios are same.

• Journal of Korean Medical classics
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• v.31 no.1
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• pp.29-43
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• 2018

Objectives : This paper studies how the people of the past deal with constipation before the introduction of modern medical knowledge. Then, the paper selected some of the methods that use food ingredients with little to no side effects, and studied them to find a basic set of data that can be applied to today's medical practices. Methods : This paper reviewed six literatures: China's Eumsunjungyo, Nonohangeon, and Shiggamboncho, and Chosun's Singnyochanyo, Donguibogam, and Jejungsinpyeon. The food cures related to constipation were studied to discover what ingredients and preparation forms were used, how they were taken, what types of prescriptions existed, and how they were applied. Results : The food cure for constipation included ingredients such as mazi, suzi, sesame, honey, yiyiren, yuliren, xingren, taoren, and rice. These ingredients are known for replenishing the body's fluid and humor and allowing the better flow of qi. Mazi porridge, suma porridge, raw sesame oil, suzhu porridge, and suxing porridge were effective in dealing with the conspitation caused by heat, and jingshen wan, yiyiren porridge, yuliren porridge, yulirenyiyiren porridge, xingren porridge, and taoren porridge were effective in taking care of conspitation caused by qi deficiency. Conclusions : With a constipation caused by heat, it is good to take mazi and spinach regularly which is helpful in cooling down the heat. For senior citizens, constipations occur due to the qi deficiency that leads to the lack of fluid and humor. In this case, suzhu porridge should be taken regularly together with milk and sesame oil in order to replenish the qi. This will tonify the amount of qi and moisten the large intestines, which will be also helpful in tonifying the body itself.

• Journal of Korean Neurosurgical Society
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• v.42 no.5
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• pp.392-399
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• 2007

Objective : Arsenic trioxide ($As_2O_3$) has been used as an anticancer agent in traditional Chinese medicine for thousand years and berberine is an isoquinoline alkaloid present that has indicated significant antimicrobial activity. We have examined the combined anticancer effects of $As_2O_3$ and berberine against the human neuroblastoma (HNB) SH-SY5Y cells in vitro, and to elucidate underlying molecular mechanism. Methods : HNB SH-SY5Y cells were treated with $2\;{\mu}M\;As_2O_3$ and $75\;{\mu}g/ml$ berberine, and their survival, cell death mechanism as well as synergistic cytotoxic effects were estimated by using MTT assay, DAPI staining, agarose gel electrophoresis, flow cytometric analysis, and western blot analysis. Results : The combined treatment of two drugs also markedly decreased cell viability. The cytotoxic effects of two drugs were revealed as apoptosis characterized by chromatin condensation, DNA fragmentation, and the loss of mitochondrial membrane potential. The apoptotic cytotoxicity was accompanied by activation of caspase-3 protease as well as decreased the expression of Bcl-2, Bid, and Bcl-x/L. In addition, the cells treated with combination of two drugs also showed significantly increased intracellular reactive oxygen species levels and lipid peroxidation compared to cells $As_2O_3$or berberine only. Conclusion : Combined treatment of $As_2O_3$ with berberine induced activation of apoptotic signaling pathways in HNB SH-SY5Y cells. These results suggest that the possibility of the combined treatment of two chemotherapeutic agents with low concentration improving cytotoxic effect for cancer cells with minimal side effects.