• 한국전산유체공학회:학술대회논문집
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• 2007.10a
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• pp.232-235
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• 2007

A comprehensive numerical study was carried out to identify the on-set condition of the cell structures of oblique detonation waves (ODWs). Mach 7 incoming flow was considered with all other flow variables were fixed except the flow turning angles varying from 35 to 38. For a given flow conditions theoretical maximum turning angle is $38.2^{\circ}$ where the oblique detonation wave may be stabilized. The effects of grid resolution were tested using grids from $255{\times}100$ to $4,005{\times}1,600$. The numerical smoked foil records exhibits the detonation cell structures with dual triple points running opposite directions for the 36 to 38 turning angles. As the turning angle get closer to the maximum angle the cell structures gets finer and the oscillatory behavior of the primary triple point was observed. The thermal occlusion behind the oblique detonation wave was observed for the $38^{\circ}$ turning angle.

• 유체기계공업학회:학술대회논문집
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• 1999.12a
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• pp.179-186
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• 1999

Three-dimensional flow analysis is implemented to investigate the flow through transonic axial-flow compressor rotor(NASA R67), and to evaluate the performances of k-$\epsilon$ and Baldwin-Lomax turbulence models. A finite volume method is used for spatial discretization. And, the equations are solved implicitly in time with the use of approximate factorization. Upwind difference scheme is used for inviscid terms, but viscous terms are centrally differenced. The flux-difference-splitting of Roe is used to obtain fluxes at the cell faces. Numerical analysis is performed near peak efficiency and near stall. And, the results are compared with the experimental data for NASA R67 rotor. Blade-to-Blade Mach number distributions are compared to confirm the accuracy of the code. From the results, we conclude that k-$\epsilon$ model is better for the calculation of flow rate and efficiency than Baldwin-Lomax model. But, the predictions for Mach number and shock structure are almost same.

• Bulletin of the Korean Chemical Society
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• v.34 no.5
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• pp.1503-1507
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• 2013

The two major symptoms characterizing Alzheimer's disease are the formation of amyloid-${\beta}$ extracellular deposits in the form of senile plaques and intracellular neurofibrillary tangles (NFTs) that consist of pathological hyperphosphorylated tau protein aggregated into insoluble paired helical filaments (PHFs). Neurons of the central nervous system have appreciable amounts of tau protein, a microtubule-associated protein. To maintain an optimal operation of nerves, the microtubules are stabilized, which is necessary to support cell structure and cellular processes. When the modified tau protein becomes dysfunctional, the cells containing misfolded tau cannot maintain cell structure. One of the pathological hallmarks of Alzheimer's disease is hyperphosphorylated tau protein. This paper shows that the small heat shock protein from humans (Hsp27) reduces hyperphosphorylated tau and prevents hyperphosphorylated tau-induced cell death of the human neuroblastoma cell line SH-SY5Y.

• The Korean Journal of Physiology and Pharmacology
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• v.8 no.6
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• pp.345-349
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• 2004

Heat shock ($43^{\circ}C$ for 60 minutes) is sufficient to induce apoptosis in a wide number of cell lines. In this study, we asked whether DNA strand breaks are responsible for this phenomenon. Using the highly sensitive comet assay for DNA damage detection, we were unable to demonstrate DNA breaks immediately after heat shock in Raji human Iymphoid cells. It showed that DNA breaks were not necessary for hyperthermic apoptosis, since its activity is indicative of DNA lesions. Here, we present a suggestion that a protein(s) is the major target for heat shock apoptosis. We firstly found glycerol, which reportedly stabilizes protein structure, showed a protective effect in Raji cells against hyperthermic apoptosis. In addition, quercetin, which modulates transcription of the heat shock protein family members, enhanced apoptotic death induced by hyperthermia. Furthermore, Raji cells are protected by a pre-mild heat treatment prior to the killing dose of heat shock.

• 한국전산유체공학회:학술대회논문집
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• 2004.03a
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• pp.154-159
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• 2004

Numerical simulations of supersonic impinging jet flows are carried out using the axisymmetric Navier-Stokes code. This paper focuses on the oscillatory flow features associated with the variation of the nozzle pressure ratio and nozzle-to-plate distance. Frequencies of the surface pressure oscillation from computational results are in accord with the measured impinging tones for various cases of nozzle-to-plate distance. The variation of this frequency with distance show a staging behavior. Computed results for the case of nozzle pressure ratio variation for a fixed nozzle-to-plate distance also demonstrate a staging behavior. These two seemingly different staging behaviors are found to obey the same frequency-distance characteristics when the frequency and the distance are normalized by using the length of the shock cell.

• The Transactions of the Korean Institute of Electrical Engineers P
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• v.58 no.4
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• pp.597-601
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• 2009

Green car such as a hybrid electrical vehicle and fuel cell vehicle is developed as a commercial target. UN/ECE/WP29 is developing GTR of HFCV and establishing the regulation and standard of electrical safety by ELSA. The regulation and standard about Electrical safety of vehicle are prescribed in ISO, UN/ECE, FMVSS, Japanese Attachment and so on, in case of insulation resistance is referred to keep more than 100/Vdc, 500/Vac. However, accurate method to measure insulation resistance agreeable to structure of vehicle does not exist now, it is actually that correctness of measurement drops according to the feature of battery and fuel cell stack. In this paper, the method to measure insulation resistance for protection against electrical shock by direct contact or indirect contact in Green Car will be indicated by making a comparison between the insulation measurement in standard of electrical safety and the experiment results for HEV and HFCV.

• 한국정보디스플레이학회:학술대회논문집
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• 2004.08a
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• pp.1229-1232
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• 2004

The ratio of optimized concentration on optical characteristics for phase-separated composite organic films (PSCOF) liquid crystal display is 30% of pre-polymer (NOA65) and 70% of ferroelectric liquid crystal (Felix). The layer structure in ferroelectric liquid crystal cell made by 30% NOA65 and 70% Felix materials is tilt-bookshelf layer structure. The angle of tilt-bookshelf structure are 17$^{\circ}$, 12$^{\circ}$ which are almost same of tilt angle of ferroelectric liquid crystal in Sm $C^{\ast}$ phase. We know that this result is from compensating the layer buckling. In this paper, we will discuss the effect of layer structure in PSCOF cell on ratio of concentration between pre-polymer and liquid crystal by x-ray measurements. We believe that technology of PSCOF is a good solution to solve the problems of align-defect and mechanical shock for future TV application and plastic LCD.

• Journal of the Korean Society for Aeronautical & Space Sciences
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• v.39 no.4
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• pp.314-320
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• 2011

In this work, optimization of two-stage shock absorption system for lunar lander has been carried out. Because of complexity of impact phenomena of shock absorption system, a 1-D constitutive model is proposed to describe the behavior of shock absorption system. Quadratic polynomial regression meta-model is constructed by using a commercial software ABAQUS with the proposed 1-D constitutive model, and sequential approximate optimization of two-stage shock absorption system has been carried out along with the constructed meta-model. Through the optimization, it is verified that landing impact force on lunar lander can be considerably reduced by changing the cell size and foil thickness of honeycomb structure in two-stage shock absorption system.

• Journal of Mechanical Science and Technology
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• v.17 no.12
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• pp.2107-2115
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• 2003

A supersonic dual coaxial jet has been employed popularly for various industrial purposes, such as gasdynamic laser, supersonic ejector, noise control and enhancement of mixing. Detailed characteristics of supersonic dual coaxial jets issuing from an inner supersonic nozzle and outer sonic nozzles with various ejection angles are experimentally investigated. Three important parameters, such as pressure ratios of the inner and outer nozzles, and outer nozzle ejection angle, are chosen for a better understanding of jet structures in the present study. The results obtained from the present experimental study show that the Mach disk diameter becomes smaller, and the Mach disk moves toward the nozzle exit, and the length of the first shock cell decreases with the pressure ratio of the outer nozzle. It was also found that the highly underexpanded outer jet produces a new oblique shock wave, which makes jet structure much more complicated. On the other hand the outer jet ejection angle affects the structure of the inner jet structure less than the pressure ratio of the outer nozzle, relatively.

• Journal of the Korean Ceramic Society
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• v.35 no.6
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• pp.610-618
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• 1998

Alumina were added to ceria based ceramic powders upto 9.7 vol% and composite powders were sprayed by plasma spraying process in order to improve the mechanical properties such as hardness fracture tough-ness and thermal shock resistance. The ceria based coating sprayed without alumina has the typical colum-nar and lamellar structure. Alumina addition has lowered the amount of columnar and lamellar sturcture Added alumina was segreagated in the grain boundary and grain of ceria based crystal accompanied with pore. The maximum value of density and the minimum value of porosity were observed at the sprayed coating with 4.8 vol% alumina. The hardness fracture toughness and thermal shock resistance were increased with alumina addition. The improvement of mechanical properties of plasma sparyed ceria based coatings result-ed from the disapperance of the columnar and lamellar sturcture by addition of alumina.