• 대한기계학회:학술대회논문집
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• 대한기계학회 2003년도 추계학술대회
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• pp.490-495
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• 2003

In steel-making process of iron and steel industry, the purity and quality of steel can be dependent on the amount of CO contained in the molten metal. Recently, the supersonic oxygen jet is being applied to the molten metal in the electric furnace and thus reduces the CO amount through the chemical reactions between the oxygen jet and molten metal, leading to a better quality of steel. In this application, the supersonic oxygen jet is limited in the distance over which the supersonic velocity is maintained. In order to get longer supersonic jet propagation into the molten metal, a supersonic coherent jet is suggested as one of the alternatives which are applicable to the electric furnace system. It has a flame around the conventional supersonic jet and thus the entrainment effect of the surrounding gas into the supersonic jet is reduced, leading to a longer propagation of the supersonic jet. In this regard, gasdynamics mechanism about why the combustion phenomenon surrounding the supersonic jet causes the jet core length to be longer is not yet clarified. The present study investigates the major characteristics of the supersonic coherent jet, compared with the conventional supersonic jet. A computational study is carried out to solve the compressible, axisymmetric Navier-Stokes equations. The computational results of the supersonic coherent jet are compared with the conventional supersonic jets.

• 대한한의학방제학회지
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• 제16권2호
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• pp.101-114
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• 2008

Objective : The purpose of this study was to investigate the anti-inflammatory effects of Hwagae-san extract(HGSE) on the peritoneal macrophage. Methods : To evaluate anti-inflammatory effects of HGSE, We measured cytokines(interleukin-6; IL-6, interleukin-12; IL-12, tumor necrosis factor-${\alpha}$; TNF-${\alpha}$) and nitric oxide(NO) production in lipopolysaccharide(LPS)-induced macrophages. Furthermore, We examined molecular mechanism using western blot and also LPS-induced endotoxin shock. Results : 1. HGSE did not have any cytotoxic effect in the peritoneal macrophages. 2. HGSE reduced LPS-induced IL-6, TNF-${\alpha}$, IL-12 and NO production in peritoneal macrophages. 3. HGSE inhibited the activation of extracelluar signal-regulated kinase(ERK), C-Jun NH2-terminal kinase(JNK) but not of p38, degradation of IkB-${\alpha}$ in the LPS-stimulated peritoneal macrophages. 4. HGSE inhibited the production of TNF-$\alpha$, IL-6 and IL-12 in serum after LPS injection. Conclusion : These results suggest that HGSE may inhibit the production of TNF-${\alpha}$, IL-6, and IL-12 through inhibition of ERK and JNK activation, and that HGSE may be beneficial for inflammatory diseases.

• 한국환경독성학회:학술대회논문집
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• 한국환경독성학회 2003년도 추계국제학술대회
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• pp.177-177
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• 2003

Methylmercury (MeHg) is a well-known neurotoxicant that causes severe damage to the central nervous system in humans. Many reports have shown that MeHg is poisonous to human body through contaminated foods and has released into the environment. Despite many studies on the pathogenesis of MeHg-induced central neuropathy, no useful mechanism of toxicity has been established so far. In this study, suppressive subtractive hybridization (SSH) was performed to identify differentially expressed genes on human neuroblastoma cell line, SH-SY5Y treated with DMSO and MeHg (6.25 uM) for 6 hr. Differentially expressed cDNA clones were sequenced and were screened by dot blot to eliminate false positive clones. 13 of 35 screened genes were confirmed using real time RT-PCR. These genes include EB1,90-kDa heat-shock protein, chromosome condensation-related SMC-associated protein and brain peptide Al, etc. Analysis of these genes may provide an insight into the neurotoxic effects of MeHg in human neuronal cells and a possibility to develop more efficient and exact monitoring system of heavy metals as ubiquitous environmental pollutants.

• 한국소음진동공학회논문집
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• 제15권2호
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• pp.184-191
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• 2005

The near-field scanning micro scope (NSOM) technique is in the spotlight as the next generation storage device. Many different types of read/write mechanism for NSOM have been introduced in the literature. In order for a near-field probe to be successfully implemented in the system, a suitable slider and suspension are needed to be properly designed. The optical slider is designed considering near-filed optics and probe array. The suspension generally supports slider performance, and tracking servo capacity in HDD. Moreover, the suspension for optical slider also should meet the optical characteristics, and is also required to satisfy shock performances for the mobility for the actuator. In this study, the optical slider and the suspension for near-field probe array are designed and analyzed.

• 한국분말야금학회:학술대회논문집
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• 한국분말야금학회 1993년도 추계학술강연 및 발표대회강연 및 발표논문 초록집
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• pp.2-2
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• 1993

The present status of the thennomechanica1 evaluation of functionally gradient materials(FGMs) for space plane application was reviewed, in which research activities and the cooperation of the national project team organized to study FGM science were demonstrated. The project team was divided into three working groups; de singing, processing and evaluation, each of which had their own tasks in the project cooperation. The testings details of the various thennomechanical tests for the FGM samples fabricated by the processing groups were described, along with their corresponding heating conditions of the real environments in the space plane application. For small-sized samples, laser beam heating test and burner heating test were well applied to study the heat shielding and heat resisting properties. Arc-heated wind tunnel test and high temperature!high velocity gas flow test were used for large-sized panel assemblies having cooling structures. The criteria for the evaluation of the heat shielding and heat resisting properties of the FGMs, as well as a crack activation mechanism in their differential temperature heating, were proposed on the basis of the observation in the burner heating test.

• International Journal of Fluid Machinery and Systems
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• 제8권1호
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• pp.23-35
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• 2015

This paper presents the rotordynamic performance measurement of oil-free turbocharger (TC) supported on gas foil bearings (GFBs) for 2 liter class diesel vehicles and comparison to floating ring bearings (FRBs). Oil-free TC was designed and developed via the rotordynamic analyses using dynamic force coefficients from GFB analyses. The rotordynamics and performance of the oil-free TC was measured up to 85 krpm while being driven by a diesel vehicle engine, and compared to a commercial oil-lubricated TC supported on FRBs. The test results showed that the GFBs increased the rotor speed by ~ 20% at engine speeds of 1,500 rpm and 1,750 rpm, yielding the reduction of turbine input energy by more than 400 W. Incidentally, an external shock test on the oil-free TC casing was conducted at the rotor speed of 60 krpm, and showed a good capability of vibration damping due to the well-known dry friction mechanism of the GFBs.

• 한국정보통신학회:학술대회논문집
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• 한국정보통신학회 2013년도 추계학술대회
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• pp.489-491
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• 2013

본 논문에서 Processing 언어를 이용하여 아두이노 기반의 컴퓨터와의 통신을 이용하여 소리를 내는 전자드럼을 설계 하였다. 먼저 피에조 센서를 이용해서 드럼패드를 구현한다. 이때 드럼패드는 센서가 파손되지 않도록 충격을 완화시킬 수 있는 구조로 제작하였다. 이 패드를 아두이노와 연결하여 센서가 충격을 받으면 감지한 신호를 아두이노로 보낸다. 그러면 신호를 받은 아두이노는 컴퓨터에 신호를 전송하고 신호를 받은 컴퓨터는 저장되어 있는 드럼소리를 출력한다. 이러한 구조를 통해서 마이크로 컨트롤러와 컴퓨터의 통신 기술을 이용한 많은 응용 가능한 부분이 있을 것으로 사료된다.

• The Korean Journal of Physiology and Pharmacology
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• 제17권3호
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• pp.217-222
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• 2013

We reported that ailanthoidol, a neolignan from Zanthoxylum ailanthoides and Salvia miltiorrhiza Bunge, inhibited inflammatory reactions by macrophages and protected mice from endotoxin shock. We examined the anti-inflammatory activity of six synthetic ailanthoidol derivatives (compounds 1-6). Among them, compound 4, 2-(4-hydroxyphenyl)-5-(3-hydroxypropenyl)-7-methoxybenzofuran, had the lowest $IC_{50}$ value concerning nitric oxide (NO) release from lipopolysaccharide (LPS)-stimulated RAW264.7 cells. Compound 4 suppressed the generation of prostaglandin (PG) $E_2$ and the expression of inducible NO synthase and cyclooxygenase (COX)-2 induced by LPS, and inhibited the release of LPS-induced pro-inflammatory cytokines from RAW264.7 cells. The underlying mechanism of compound 4 on anti-inflammatory action was correlated with the down-regulation of mitogen-activated protein kinase and activator protein-1 activation. Compound 4 is potentially an effective functional chemical candidate for the prevention of inflammatory diseases.

• 천문학회보
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• 제41권1호
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• pp.64.4-65
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• 2016

Observations of the early photons from evolution of optical afterglows or internal shock provides the crucial clues on the nature of the bursts and environments. Hundreds of GRBs afterglow observations in multi-wavelength region have been made mainly thanks to the fast (~ 60 seconds after the trigger) localisation GRB by Swift and its fast alert to the ground telescope. It helps to improve our understandings tremendously, however many enigmas still remain, such as burst mechanism, transition prompt emission to the afterglow, early optical flash, rise phase of the early optical light curve and some missing afterglows. They could be addressed by fast slewing and multi colour and IR follow-up by future telescopes. The primary aim of UFFO/Lomonosov is to follow up optical fast ever, within a couple of seconds after trigger by onboard X-ray telescope. Its optical FOV is $30{\times}30degrees$. As a key instrument, the Slewing Mirror to redirect the optical beam from GRBs rapidly to the Ritchey-Chretien telescope. The status and launch schedule of the UFFO/Lomonosov and its test performance will be reported and prospects for the next missions will be discussed.

• 한국추진공학회:학술대회논문집
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• 한국추진공학회 2010년도 제35회 추계학술대회논문집
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• pp.363-366
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• 2010

여러 형태의 풍동장치 중에서 Ludwieg Tube(LT)는 높은 레이놀즈수 유동을 실현할 수 있는 가장 적합한 장치로 알려져 있다. 일반적으로 LT는 격막의 위치에 따라 두 종류로 구분된다. 본 연구에서는 상류막 방식과 하류막 방식 LT의 작동특성을 조사하기 위하여, 수치해석적인 방법을 적용하였다. 수치해석에서는 2차원 축대칭, 비정상, 압축성 Navier-Stokes 방정식에 유한체적법을 적용하였다. 그 결과, 본 수치해석은 시동과정의 유동 메커니즘을 파동선도를 이용하여 상세하게 설명하였으며, 시동 시간과 작동시간의 특성을 조사하였다.