• Proceedings of the Korean Society for Noise and Vibration Engineering Conference
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• 2014.10a
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• pp.273-276
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• 2014

The development of a vehicle-mounted radar to detect the location of enemy artillery is mainly mounted during operation to the mobility of the equipment and efficiency of utilization range. It is equipped with an electronic device responsible for the operation of the radar system. Electronic equipments is performed functionality imparted without an error-specific in spite of disturbances such as vibration / shock caused by vehicle movement. Therefore, vibration / shock resistance is held to prevent damaging from vibration / shock generated from the outside environment during operation. In addition, a standardized and specified cabinet structure equipped with electronic equipment is placed in shelter to ensure additional safety for vibration / shock. In this study, it is evaluated by analytical method with vibration / shock resistance of the cabinet structures for ensuring structural safety factor is applied to the aluminum. It is verified the reliability of the structure and structural dynamics to verify by calculated natural frequencies adding the weight of the cabinet structure and the structural displacement and stress results confirmed with vibration / shock caused by the vehicle movement.

• Journal of Ocean Engineering and Technology
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• v.36 no.3
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• pp.161-167
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• 2022

Three-dimensional finite element analysis (3D-FEA) models have been used to evaluate the shock-resistance responses of various equipments, including armaments mounted on a warship caused by underwater explosion (UNDEX). This paper aims to check the possibility of using one-dimensional (1D) FEA models for the shock-resistance responses. A frigate was chosen for the evaluation of the shock-resistance responses by the UNDEX. The frigate was divided into the thirteen discrete segments along the length of the ship. The 1D Timoshenko beam elements were used to model the frigate. The explosive charge mass and the stand-off distance were determined based on the ship length and the keel shock factor (KSF), respectively. The UNDEX pressure fields were generated using the Geers-Hunter doubly asymptotic model. The pseudo-velocity shock response spectrum (PVSS) for the 1D-FEA model (1D-PVSS) was calculated using the acceleration history at a concerned equipment position where the digital recursive filtering algorithm was used. The 1D-PVSS was compared with the 3D-PVSS that was taken from a reference, and a relatively good agreement was found. In addition, the 1D-PVSS was compared with the design criteria specified by the German Federal Armed forces, which is called the BV043. The 1D-PVSS was proven to be relatively reasonable, reducing the computing cost dramatically.

• Transactions of the Korean Society of Pressure Vessels and Piping
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• v.7 no.3
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• pp.15-22
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• 2011

The chemistry factor and RTPTS margin for domestic reactor pressure vessel materials were analyzed by using the surveillance data which have been obtained from 8 nuclear power plants in Korea. The surveillance data have been used to assess the integrity of the pressure vessel under the pressurized thermal shock (PTS) event. The chemistry factor, which is determined by the Cu and Ni contents of vessel materials, is considered a proper tool to assess the $RT_{PTS}$. The chemistry factors, which were obtained from the surveillance data of domestic reactor pressure vessels, were investigated and compared with those of Regulatory Guide 1.99 in this study. Regressions for ${\Delta}RT_{NDT}$ were performed to expect the chemistry factor as a function of Cu and Ni, and to estimate $RT_{PTS}$ margin. The margin analysis was performed by comparing the regression graphs and standard deviations with those of Regulatory Guide 1.99. The standard deviations calculated by using the domestic surveillance data for base metal and welds are almost same as the standard deviations which are suggested on Regulatory Guide 1.99, Rev.2.

• Journal of Ginseng Research
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• v.32 no.4
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• pp.315-323
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• 2008

In the previous studies, we isolated the compound K rich fractions (CKRF) and showed that CKRF inhibited Toll-like receptor (TLR) 4- or TLR9-induced inflammatory signaling. To extend our previous studies,1) we investigated the molecular mechanisms of CKRF in the TLR4-associated signaling via nuclear factor (NF)-${\kappa}B$, and in vivo role of CKRF for induction of tolerance in lipopolysaccharide (LPS)-induced septic shock. In murine bone marrow-dervied macrophages, CKRF significantly inhibited the induction of mRNA expression of proinflammatory mediators such as tumor necrosis factor-${\alpha}$, interleukin-6, cyclooxygenase-2, and inducible nitric oxide synthase. In addition, CKRF significantly attenuated the transcriptional activities of TLR4/LPS-induced NF-${\kappa}B$. Nuclear translocation of NF-${\kappa}B$ in response to LPS stimulation was significantly abrogated by pre-treatment with CKRF. Furthermore, CKRF inhibited the recruitment of p65 to the interferon-sensitive response element flanking region in response to LPS. Finally, oral administration of CKRF significantly protected mice from Gram-negative bacterial LPS-induced lethal shock and inhibited systemic inflammatory cytokine levels. Together, these results demonstrate that CKRF modulates the TLR4-dependent NF-${\kappa}B$ activation, and suggest a therapeutic role for Gram-negative septic shock.

• Yonsei Medical Journal
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• v.59 no.9
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• pp.1041-1048
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• 2018

Purpose: Heat shock factor 1 (HSF1) is a key regulator of the heat shock response and plays an important role in various cancers. However, the role of HSF1 in gastric cancer is still unknown. The present study evaluated the function of HSF1 and related mechanisms in gastric cancer. Materials and Methods: The expression levels of HSF1 in normal and gastric cancer tissues were compared using cDNA microarray data from the NCBI Gene Expression Omnibus (GEO) dataset. The proliferation of gastric cancer cells was analyzed using the WST assay. Transwell migration and invasion assays were used to evaluate the migration and invasion abilities of gastric cancer cells. Protein levels of HSF1 were analyzed using immunohistochemical staining of tissue microarrays from patients with gastric cancer. Results: HSF1 expression was significantly higher in gastric cancer tissue than in normal tissue. Knockdown of HSF1 reduced the proliferation, migration, and invasion of gastric cancer cells, while HSF1 overexpression promoted proliferation, migration, and invasion of gastric cancer cells. Furthermore, HSF1 promoted the proliferation of gastric cancer cells in vivo. In Kaplan-Meier analysis, high levels of HSF1 were associated with poor prognosis for patients with gastric cancer (p=0.028). Conclusion: HSF1 may be closely associated with the proliferation and motility of gastric cancer cells and poor prognosis of patients with gastric cancer. Accordingly, HSF1 could serve as a prognostic marker for gastric cancer.

• Advances in materials Research
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• v.6 no.2
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• pp.155-168
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• 2017

The terrorist attacks and dangers by bomb blast have turned into an emerging issue throughout the world and the protection of the people and structures against terrorist acts depends on the prediction of the response of structures under blast and shock load. In this paper, behavior of aluminum and unidirectionally reinforced E-Glass Epoxy composite plates with and without focal circular holes subjected to shock loading has been identified. For isotropic and orthotropic plates (with and without holes) the classical normal mode approach has been utilized as a part of the processing of theoretical results. To obtain the accurate results, convergence of the results was considered and a number of modes were selected for plate with and without hole individually. Using a shock tube as a loading device, tests have been conducted to composite plates to verify the theoretical results. Moreover, peak dynamic strains, investigated by experiments are also compared with the theoretical values and deviation of the results are discussed accordingly. The strain-time histories are likewise indicated for a specific gauge area for aluminum and composite plates. Comparison of dynamic-amplification factors between the isotropic and the orthotropic plates with and without hole has been discussed.

• Transactions of the Korean Society for Noise and Vibration Engineering
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• v.13 no.9
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• pp.679-687
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• 2003

Shock wave reduction in electrorheological(ER) smart structures is studied. ER insert is a composite structure comprising two elastic outer layers between which is sandwiched layer of ER fluid. When a voltage is applied across the outer layers. the shear modulus and the loss factor of the ER fluid are enabled, and thus the dynamic properties of the composite structure is altered. For the shock wave reduction in a hull mount of a submerged structure, ER inserts are made on the hull mount structure. To investigate the ER insert shape. many types of ER insert pattern are considered. Modal test of ER insert structures is performed to obtain the mode shapes, natural frequencies and the acceleration transmissibility. The acceleration transmissibility is reduced at such a frequency region when an electric field is applied. It is observed that the natural frequencies and mode shapes can be tunable by applying electric field. The ER-inserted hull mount is installed in an integrated system and the overall performance of shock wave reduction is tested. The possibility of shock wave reduction in the hull mount is demonstrated.

• The Journal of Korean Academic Society of Nursing Education
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• v.25 no.1
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• pp.17-26
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• 2019

Purpose: This study was conducted to verify the validity and reliability of the modified Transition Shock Scale for use among nursing students. Methods: From March 8-April 3, 2018, 207 nursing students participated in this study and were asked to complete self-reported questionnaires, including transition shock, clinical stress, and adapting to clinical practicums. The IBM SPSS Win 18.0 and AMOS 18.0 programs were used for data analysis. Results: A confirmatory factor analysis supported good convergent and discriminant validities ($x^2/df=1.58$, TLI=.92, CFI=.95, RMSEA=.053, AVE=.51-.68, CR=.75-.68). Correlations among transition shock, clinical stress (r=.34, p<.001), and adapting to clinical practicums (r=-.54, p<.001) were significant. Cronbach's alpha for the overall scale was .85, and for the six subfactors it ranged from .65 to .75. Conclusion: The findings suggest that the 17-item transition shock questionnaire is an appropriate instrument for measuring nursing students' transition shock with good validity and reliability.

• Transactions of the Korean Society of Mechanical Engineers A
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• v.26 no.11
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• pp.2390-2398
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• 2002

For integrity analysis of nuclear reactor pressure vessel, including the Pressurized thermal shock analysis, the fast and accurate calculation of the stress intensity factor at the crack tip is needed. For this, a simple approximation scheme is developed and the resulting stress intensity factors for axial semi-elliptical cracks in cylindrical vessel under various loading conditions are compared with those of the finite element method and other approximation methods, such as Raju-Newman's equation and ASME Sec. Xl approach. For these, three-dimensional finite-element analyses are performed to obtain the stress intensity factors for various surface cracks with t/R = 0.1. The approximation methods, incorporated in VINTIN (Vessel INTegrity analysis-INner flaws), utilizes the influence coefficients to calculate the stress intensity factor at the crack tip. This method has been compared with other solution methods including 3-D finite clement analysis for internal pressure, cooldown, and pressurized thermal shock loading conditions. The approximation solutions are within $\pm$2.5% of the those of FEA using symmetric model of one-forth of a vessel under pressure loading, and 1-3% higher under pressurized thermal shock condition. The analysis results confirm that the VINTIN method provides sufficiently accurate stress intensity factor values for axial semi-elliptical flaws on the surface of the reactor pressure vessel.

• Journal of The Korean Astronomical Society
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• v.49 no.3
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• pp.83-92
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• 2016

The Toothbrush radio relic associated with the merging cluster 1RXS J060303.3 is presumed to be produced by relativistic electrons accelerated at merger-driven shocks. Since the shock Mach number inferred from the observed radio spectral index, M_radio ≈ 2.8, is larger than that estimated from X-ray observations, M_X ≲ 1.5, we consider the re-acceleration model in which a weak shock of M_s ≈ 1.2 - 1.5 sweeps through the intracluster plasma with a preshock population of relativistic electrons. We find the models with a power-law momentum spectrum with the slope, s ≈ 4.6, and the cutoff Lorentz factor, γ_e,c ≈ 7-8×10⁴ can reproduce reasonably well the observed profiles of radio uxes and integrated radio spectrum of the head portion of the Toothbrush relic. This study confirms the strong connection between the ubiquitous presence of fossil relativistic plasma originated from AGNs and the shock-acceleration model of radio relics in the intracluster medium.