• Journal of Korean Academy of Oral and Maxillofacial Radiology
• /
• v.29 no.2
• /
• pp.451-458
• /
• 1999

Purpose : To determine normal CT number range of parotid gland by analyzing the change by age increase and the difference among individuals and between both sexes in CT number of normal parotid gland. Materials & Methods : 134 subjects who took the CT scan between the period of Jan. 1996 and Dec. 1997 at Yonsei University, Dental Hospital were selected. Criteria for selection were that the patients must be within the normal range clinically and radiologically, and the entire parotid gland on the axial view must be shown. Among the axial views. the one showing the greatest parotid gland size was selected and its CT number was recorded. Also. CT numbers from both masseter muscle were recorded as its control. Results : There was statistically significant correlation between CT number of right and left of parotid glands and masseter muscles. With the increase of age. there is a significant decrease in the CT number of parotid gland(p<0.05). There was no statistically significant difference in CT number between sexes except the 7th decade and beyond age group of parotid gland(p>0.05). Conclusion : As age increases, CT number of parotid gland has a tendency to decrease, and there is no significant difference in the CT numbers between left and right parotid gland. Therefore in the CT scan of patients suspected of having a salivary gland disease of the parotid gland. to consider normal range of the age-dependent CT numbers of parotid gland and compare the CT numbers of the right and left parotid gland might be useful in diagnosing the disease.

• Korean Journal of Fisheries and Aquatic Sciences
• /
• v.41 no.4
• /
• pp.253-260
• /
• 2008

Gonadal development, gametogenesis, reproductive cycle, spawning, relative weight of flesh, and onset of sexual maturity of the murex shell, Ceratostoma rorifluum, collected from the rocky intertidal zone of Daehang-ri, Buan-gun, Jeollabuk-do, Korea were investigated monthly from January to December 2005 both cytologically and histologically. The gonads were widely placed on the digestive gland located in the posterior spiral fleshy part in the shell. C. rorifluum had separate sexes, and was an internal fertilizer. The sex ratio of females to males was approximately 1:1. The ovary and testis contained a great number of oogenic follicles and spermatogenic tubules, respectively. The oogonia and fully ripe oocytes were $15-19{\mu}m$ and $150-160{\mu}m$ in diameter, respectively, and the cytoplasm of the ripe oocytes contained a number of yolk granules. The relative weight of flesh reached a maximum in August($39.35{\pm}0.40%$), and then decreased rapidly in November($32.75{\pm}1.20%$). The percentages of female and male snails at first sexual maturity with shell heights ranging from 12.1-14.0 mm were 60.0% and 52.9%, respectively, while 100% of the snails of both sexes with shell heights over 18.1 mm were reproductively active. Based on the gonadal development and histological observations, the reproductive cycle of the snail could be categorized into five successive stages: early active(December to May), late active(March to July), ripe(June to September), spawning(July to October), and recovery(October to March). C. rorifluum spawned once a year between July and October, and the majority of spawning occurred in September when the seawater temperature exceeded $23.5^{\circ}C$.

• Toxicological Research
• /
• v.16 no.2
• /
• pp.163-172
• /
• 2000

Recently, there is a worldwide concern that a great number of man-made chemicals have a hormone-like action both in humans and in animals. DECD is developing screening programs using validated test systems to determine whether certain substances may have an effect in humans. In the present study. the establishment oj repeated-dose toxicity test method was tried. Flutamide. an anti-androgenic agent. was administered by gavage to Sprague-Dawley rats for 28 days at dose levels of 0. 0.5. 3 and 18 mg/kg body weight (10-15 rats/sex/group) to examine the effects on general findings. especially reproductive and endocrine parameters. Clinical signs. body weights, food consumption, and sexual cycle were checked and measured. For the gross and microscopic examinations. 10 rats/sex/group were sacrificed at the end of dosing period and the remaining animals of control and high dose groups (5 each) were sacrificed after 14 days recovery. Examinations for hematology and clinical chemistry were carried out at necropsy. There were no treatment-related changes in clinical signs. body weights, food consumption. gross necropsy. hematology and clinical chemistry at all doses of both sexes. The period and regularity of sexual cycle were not adversely affected at all doses by the test agent. At 18 mg/kg. both decreased weights of prostate, seminal vesicle and epididymis in males and increased weights of spleen and thymus in females were observed. In addition, decreased number of spermatids and sperms. increased serum testosterone concentration and increased incidence (100%) of interstitial cell hyperplasia were seen in males. At 18 mg/kg of the recovery group. decreased prostate weight. reduced sperm count and increased incidence (20%) of interstitial cell hyperplasia in males and increased thymus weight in females were observed. At 3 mg/kg. reduced sperm count was found. There were no adverse effects on parameters examined at 0.5 mg/kg of both sexes. The results suggested that the potential target organs of flutamide may be accessory sexual glands including testes for males and spleen and thymus for females. Taken together. this test method was found to be a useful screening test system for endocrine disrupting chemicals.

• Asian-Australasian Journal of Animal Sciences
• /
• v.6 no.3
• /
• pp.451-461
• /
• 1993

Four hundred and eighty broiler chicks of both sexes were obtained from commercial hatchery (Hubbard) and raised on floor pens. All chicks were allowed free access to food from 0 to 7 and 20 to 56 days of age. At 7 days of age, all broilers were weighed individually, and divided into five groups as follows: 1. feed ad libitum as the control; 2. allowed free access to food 3 days and starved 1 day ($3{\times}1$); 3. allowed free access to food 2 days and starved 1 day ($2{\times}1$); 4. allowed free access to food 1 day and starved 1 days ($1{\times}1$) and; 5. allowed free access to food 2 days and starved 2 days ($2{\times}2$). Broilers were restricted for 12 days (d 7 through 17) of a 56-day trial. Broilers were fed a commercial starter diet (crude protein 23.8% and ME 3,070 kcal/kg) for 21 days, and commercial finisher diet (crude protein 20% and ME 3,160 kcal/kg) from 22 to 56 days of age. Although there was compensatory growth in some groups, (the $1{\times}1$ female group, and the $3{\times}1$ and $2{\times}1$ male grous), its level was not sufficient to achieve normal body weight at market age. There was sexual dimorphism for accelerated growth as well as differences in the ability to achieve a complete compensation of growth to the weight, feed conversion ratio, and body composition of ad libitum chicks. Early feed restriction could be used to reduce production cost because of the lower fed conversion ratio, mortality rate and the amount of starter diet consumed by broilers. The response of chicks to early feed restriction might depend on the degree of feed restriction, the method of feed restriction, duration of feed restriction, and sexes.

• Maxillofacial Plastic and Reconstructive Surgery
• /
• v.15 no.4
• /
• pp.329-337
• /
• 1993

Improvement of orthognathic surgical techniques make it possible to design esthetic surgical correction for total esthetic face. In order to find the esthetic line which guide esthetic surgical correction in patients of orthognathic surgery, cephalometric soft tissue analysis of esthetic faces were performed. In esthetic Korean young adults, 25 males and 25 females who were within 1 S.D. of E-line, ANB, P/A facial height ratio, were analyzed in natural position keeping their face eye level. 1. Sn position is constant in males and females. The Sn-N'-N' Vertical plane angle is $5.3^{\circ}$ in both sexes. Sn is positioned in front of 5 mm in female 7 mm in male from the N' vertical plane. 2. The Sn-Ls line make constant angle to horizontal plane with $72.5^{\circ}$ in both sexes, which is called "upper esthetic line". The Ls-Pg' line makes constant angle to $72.4^{\circ}$ (range $72.2^{\circ}$ in female to $72.6^{\circ}$ in male), which is called "lower esthetic line". 3. When inter-esthetic line angle (the Sn-Ls line to Ls-Pg' line) has $144.9^{\circ}$, lower third face has esthetic upper and lower lip. 4. In treatment planning, Sn is first corrected in proper position, and then upper and lower esthetic line are established with the angle of 144.9. The maxilla is moved to tangent Ls to the upper esthetic line, and mandible is moved to tangent Li and Pg' to the lower esthetic line, according to the "y"-shaped esthetic lines, then lower third face showes esthetics.

• Asian-Australasian Journal of Animal Sciences
• /
• v.14 no.7
• /
• pp.1003-1007
• /
• 2001

This experiment was conducted to investigate the effects of dietary SAA (sulfur-containing amino acids) on growth performance, nutrient digestibility and blood urea nitrogen (BUN) content, and to determine the optimal SAA:lysine ratio for growing barrows and gilts. A total of 150 pigs (75 barrows and 75 gilts, Landrace${\times}$Yorkshire${\times}$Duroc) were assigned to 6 treatments with 5 replicates of 5 pigs per pen. All pigs were fed diets containing either 1.12 (for barrows) or 1.33% (for gilts) dietary lysine with increasing SAA levels (50, 55 and 60% of dietary lysine) in a $2{\times}3$ factorial design. Throughout the whole experimental period (15 to 54 kg body weight), there was no interaction between sexes and SAA:lysine ratios on ADG, ADFI and FCR. However, increasing the SAA:lysine ratio from 50 to 60% in a diet showed a trend to increase ADG and ADFI of barrows. None of differences in nutrient digestibilities except for calcium and phosphorus were observed and gilts showed higher digestibility of calcium and phosphorus (p<0.05). Among dietary SAA:lysine ratios, there were no differences in apparent nutrient digestibility. Mean values of the essential amino acids (EAA), non-essential amino acids (NEAA) and total amino acids (TAA) digestibilities were higher in gilts than barrows (p<0.01). However, no differences in mean value of EAA, NEAA and TAA digestibilities were observed among dietary SAA:lysine ratios. Between sexes and among SAA:lysine ratios, no significant difference in BUN concentration was observed. This study demonstrated that the optimal inclusion ratio of SAA:lysine was 55% and below 50% in barrows and gilts, respectively.

• Toxicological Research
• /
• v.33 no.1
• /
• pp.15-23
• /
• 2017

Acanthopanax divaricatus (Siebold & Zucc.) Seem. var. albeofructus (ADA), a traditional medical herb, has been used to treat arthritis and muscular injury, to strengthen muscle and bone, and to get vital energy. However, information regarding its toxicity is limited. ADA was administered by oral gavage to groups of rats at doses of 0 (control), 1,000, 1,500, 2,000, 2,500, and 3,000 mg/kg five times per week for 13 weeks. Mortality, clinical signs, body weights, food consumption, hematology, serum chemistry, urinalysis, organ weights, necropsy, histopathological finding, vaginal cytology, and sperm morphology were compared between control and ADA-treated groups. Salivation was intermittently observed in both sexes receiving 2,500 and 3,000 mg/kg directly after dosing. Absolute liver weights increased in females receiving 2,000, 2,500, and 3,000 mg/kg ADA (P < 0.05, P < 0.01, and P < 0.01, respectively) and so did the relative liver weights (P < 0.001). Salivation and increased liver weight were ADA-related changes but not considered to be adverse effects. Salivation was intermittent and transient, and the liver weight increase was minor and not accompanied by other changes such as hepatic morphological or functional alterations. The no-observed-adverse-effect-level was determined to be at least 3,000 mg/kg in both sexes of rats.

• Development and Reproduction
• /
• v.20 no.3
• /
• pp.197-205
• /
• 2016

Adipose tissue is one of the major endocrine gland. More recently, local production of steroids in adipocytes differentiated from mouse 3T3-L1 cell-line was reported. We hypothesized that rat adipocytes have steroidogenic machinery and the expression patterns of the components might be differentially regulated, depending on the distribution and sex. To verify this hypothesis, we collected the adipose tissues depot-and sex-specifically at postnatal day (PND) 30, and performed quantitative RT-PCRs. In overall aspects, the abundances of the transcripts were lower in the brown adipose of both sexes. $3{\beta}-HSD$ transcript levels in female abdominal and reproductive adipose, CYP17 transcript levels in female reproductive adipose, $17{\beta}-HSD$ transcript levels in female abdominal and reproductive adipose, and CYP19 transcript levels in female abdominal adipose were significantly lower than those of male counterparts. Similar to steroidogenic factors, the abundance of the $ER-{\alpha}$ transcripts were generally lower in the brown adipose of both sexes. $ER-{\beta}$ transcripts were more abundant in male white adipose depots than their female counterparts. The levels of LHR transcripts in female reproductive adipose were significantly higher than those of male counterpart. In conclusion, our study demonstrated that the expressions of steroidogenesis-related genes were depot- and sex-specifically occurred in the immature male and female rat adipose tissues. Our study suggested that the adipose tissues are not only targets but de novo synthesizing sites of sex steroid(s), though the synthesizing activities could be much less than in gonads. Further researches in this field will be helpful for understanding the adipose physiology and for medical application such as sex-specific steroid supplement therapies for older populations.

• Journal of the Korean Home Economics Association
• /
• v.38 no.7
• /
• pp.133-152
• /
• 2000

This study was inquire into the state of the family ethics during the period of the beginning of 1880′s to the 3.1 independence movement of 1919 which has been the black period in the history of Korean family ethics. The research was conducted by analyzing the newspapers, magazines, related literature and articles of the period. It was the beginning of the 1860′s and by the "Cheondo-Kyo" (the Religion of the Heavenly) way that the issues regarding the equality of sexes as the central concern of the modem family ethics came to be the object of the social discourse for the first time in Korean history. The social discourse had come to be positively activated around 1900, when the intellectuals of the "Korean enlightenment" had begun to the feel necessity of the modernization of Korean socialite and the importance of the women education as the essential part of it. However, the activation of the social discourse itself, especially with the newspapers of that period did not mean the changes of the traditional Confucian family ethics, but the discourse of the modernizing forces had become the seeds for changing the family ethics of the Korean people. The made chauvinistic nature of the family ethics of the period was not so much different from those of the preceeding patriarch societies, but the state of the family ethics during the period are characterized by several social phenomenon such as the rising needs of using the "Hangle"(Korean alphabet) instead of Chinese character for the equal education of the both sexes, increasing practices of the early marriage, customs of trade marriage in accordance with the demand of excessive weeding presents, and regarding social consciousness of the traditional family ethics as patriotics attitude against the Christian rejection of the ancestor worship ritual.

• Journal of the Korean Home Economics Association
• /
• v.35 no.1
• /
• pp.169-190
• /
• 1997

The purpose of this study is to investigate the perception of middle school students about Home Economics course especially in the area of Food and Nutrition. For this purpose anempirical survey was conducted using structured questionnaire from 482 students in the 2nd grade of middle school. The questionnaire contained questions about the general concept of home Economics course and general concept and the degree of the perceived need of Food and Nutrition part of the course. The data of analysis are frqequency percentile mean standard-deviation chi-square one-way ANOVA t-test and Scheff-test. The major findings of this study are as follows. The major findings of this study are as follows. First students show a tendency to perceive Home Economics education is $\ulcorner$related with ethics of human life for both sexes$\lrcorner$which is stronger in girls than in boys. Boys had a tendency to perceive that Home economics is related with $\ulcorner$home making skills in food clothing housings etc.$\lrcorner$or $\ulcorner$for girls and women only $\lrcorner$which is weaker in girls. Second students also show a tendency to perceive Home Economics is important and to agree that Home Economics must be taught to both sexes. This tendency is stronger in girls than in boys, Third students show a tendency to perceive that food and Nutrition part is related with $\ulcorner$meeting problems in food choices and nutrition$\lrcorner$which is stronger in girls than in boys. Fourth girls are more interested in Food and Nutrition part than the other parts and likely to practice what they learned in Food and Nutrition part of their 1st grade and became to pay attention to their eating patterns. These tendencies are weaker in boys.