• Korean Journal of Biological Psychiatry
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• v.19 no.2
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• pp.91-98
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• 2012

Objectives : The aim of this study was to examine the effects of brain-derived neurotrophic factor (BDNF) genetic polymorphism and job stress on the severity of alcohol drinking. It was hypothesized that individuals with the Met/Met BDNF genotype would be more vulnerable than those carrying the Val allele. Methods : Participants were 133 healthy Korean adults (mean age $28.2{\pm}1.1$). Job stress and the severity index of drinking were investigated through self-reported questionnaires. BDNF (rs6265) gene was genotyped. Results : There was no significant association between job stress and the severity of alcohol drinking. Although the severity of alcohol drinking was not associated with BDNF genetic polymorphism, there was a significant difference in men according to genotype and job stress. Men with homozygous BDNF Met allele were more severe in alcohol drinking when job stress was high, less severe in alcohol drinking when job stress was low than those carrying the Val allele (F = 4.47, p = 0.038). Also higher level of job stress was correlated with higher severity of alcohol drinking in men homozygous for BDNF Met allele (rs = 0.620, p = 0.005). Conclusions : These findings suggest the possibility that Met allele could have differential susceptibility, with men homozygous for BDNF Met allele being more susceptible to both more adverse and less adverse environmental influences.

• Anxiety and mood
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• v.16 no.2
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• pp.91-97
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• 2020

Objective : The suicide mortality rate among Koreans was ranked first among the OECD countries in 2018. Alcohol consumption is a significant risk factor for suicidal behavior. This study examined the relationship between the severity of subjects' drinking habits and the suicidal ideation among Koreans according to gender and age. Methods : The data of 113,602 people who visited the Kangbuk Samsung Hospital Health Screening Center from January 2013 to December 2014 were used. The severity of subjects' harmful drinking habits was assessed using the Korean version of the Alcohol Use Disorders Identification Test (AUDIT-K). The relationship between the severity of harmful drinking and suicidal ideation was compared using logistic regression analyses. We also examined the tendency through p for trend to identify a trend. Results : Of the 113,602 study subjects, 6,586 (5.8%) responded that they had thought of committing suicide. After controlling for gender, marriage, education, body mass index (BMI), depression and anxiety, the results showed that the higher the level of harmful drinking, the higher the suicidal ideation. Conclusion : This study found that, even after controlling depression and anxiety, the severity of drinking could be a significant risk factor for suicidal ideation.

• Journal of Korean Biological Nursing Science
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• v.19 no.1
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• pp.48-54
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• 2017

Purpose: This study was done to identify the influence of severity of drinking problem, circadian rhythm and sleep quality in patients with alcohol use. Methods: A descriptive study design was utilized. Data were collected using self-report questionnaires from 139 patients with alcohol use disorder who were admitted to a psychiatric hospital in D city, Korea. The questionnaires included Alcohol Use Disorders Identification Test (AUDIT), Composite Scale of Morningness (CMS), Pittsburgh Sleep Quality Index (PSQI), and Korea sleep scale A. Data were analyzed using descriptive statistics, Pearson's correlation coefficients, and multiple regressions using the SPSS 20.0 program. Results: There was significant correlations among severity of problem drinking, circadian rhythm, sleep quality and sleep disorder. The significant factors influencing sleep disorder were severity of problem drinking(${\beta}=.12$, p= .042), circadian rhythm(${\beta}=-.14$, p= .039) and sleep quality(${\beta}=.63$, p= < .001). This model explained 56% of variance in sleep disorder(F = 57.34, p= < .001). Conclusion: The results of this study suggest that the development of sleep intervention programs for alcohol use disorder patients needs to consider severity of alcohol use, circadian rhythm and sleep quality, and sleep assessment and intervention are needed the early stage of the treatment and recovery process.

• KSCE Journal of Civil and Environmental Engineering Research
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• v.30 no.6D
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• pp.577-585
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• 2010

Traffic accidents are caused by several factors such as drivers, vehicles, and road environment. It is necessary to investigate and analyze them in advance to prevent similar and repetitive traffic accidents. Especially, the human factor is most significant element and traffic accidents by drinking-driving caused from human factor have become social problem to be paid attention to. The study analyzes traffic accidents resulting from drinking-driving and the effects of driver's attributes and environmental factors on them. The study is composed as two parts. First, the log-linear model is applied to analyze that accidents by drinking or non-drinking driving associate with road geometry, weather condition and personal characteristics. Probability is tested for drinking-driving accidents relative to non-drinking drive accidents. The study analyzes probability differences between genders, between ages, and between kinds of vehicles through odds multipliers. Second, traffic accidents related to drinking are classified into property damage, minor injury, heavy injury, and death according to their severity. Heavy injury is more serious than minor one and death is more serious than heavy injury. The ordinal regression models are established to find effecting factors on traffic accident severity.

• The Journal of Korean Society for School & Community Health Education
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• v.14 no.2
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• pp.47-57
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• 2013

Backgrounds: According to a high interest in health these days, a bicycle is being highlighted as a means of leisure activity and auxiliary transportation means. Along with an increase in this interest, there is tendency that even the width of bicycle utilization gets diverse and that bicycle accident is also rapidly growing. Purpose: The purpose of this study was to suggest a prevention measure available for reducing occurrence of bicycle accidents by analyzing the Epidemiological characteristics according to age and injury severity in bicycle-injured patients. Methods: This study analyzed 115 materials suitable for this study by examining a medical record of patients, who received the hospitalized treatment owing to bicycle accident from January 1, 2011 to December 31 at one general hospital in S city. Results: The male-and-female ratio of bicycle-injured patients stood at about 7:3. The average age was 38.14(${\pm}21.59$) years old. The largest injury happened in 40-59 years old(31.3%). The averagely hospitalized period was 17.33(${\pm}18.12$) days. Injury severity was the ratio of 2:8 in a mild case versus a serious case. As for drinking and smoking characteristics according to age, the injury occurred the most in between 40 and 59 years old for people with drinking and smoking and in under 19 years for people without drinking and smoking. According to injury severity, the ratio of serious case got higher in the higher age. This was indicated(${\chi}^2$=15.675, p=0.001) to be statistically significant. Conclusion: In this study, a bicycle accident was indicated to have high injury risk in young children, adolescents, and old-age group. Prevention measure and publicity are demanded for reducing injury occurrence such as the prevention education for bicycle accident and wearing protective gear focusing on the ages of corresponding to groups with risk of injury occurrence. In addition, the security of safe movement route is necessarily demanded in order to increase application level as an auxiliary transportation means.

• The Journal of Korean Medicine
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• v.29 no.1
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• pp.134-145
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• 2008

Objectives : This study investigated the relationship between drinking, smoking and stress of workers by analyzing heart rate variability. The subjects were workers in the automobile manufacturing industry. Methods : The subjects consisted of 21,239 and 19,999 industrial workers who had received health examination by Korean oriental medicine and submitted questionnaires about drinking history and smoking history, during 8 months from April to November. The subjects were categorized into drinking history and smoking history. The heart rate variability was measured for five minute at rest using SA-3000P (Medicore) and reported stress severity as stress index, stress resistance and fatigue. We analyzed the relationship between drinking, smoking and stress into frequencies, $x^2$-test using the SPSS Ver. 12.0. Results : Regarding the relationship between drinking and stress index orstress resistance, there was no statistically significant difference, but regarding the relationship between drinking and fatigue, the drinker group had a significantly higher level of fatigue than the non-drinker group. There was a statistically significant difference in stress index, stress resistance and fatigue between the current-smoker group and others. Stress resistance of the current-smoker group had lower levels than the non-smoker group or ex-smokers. On the other hand, stress index and fatigue of the current-smoker group had higher levels than the non-smoker group or ex-smokers. Conclusions : The above results revealed that drinking and smoking could put workers under a lot of stress. Smoking workers were especially apt to be under stress and had difficulty in alleviating stress.

• Korean Journal of Biological Psychiatry
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• v.18 no.2
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• pp.101-108
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• 2011

Objectives The aim of this study is to explore the association among DRD4 polymorphism, temperament and alcohol drinking behavior of Koreans in their early adulthood. Method Participants were 172 healthy Korean adults (mean age $28.1{\pm}0.8$). Their temperament was assessed with the Temperament and Character Inventory (TCI) and their alcohol drinking behavior were evaluated with a self-reported questionnaire including the CAGE and the Korean version of Alcohol Use Disorder Identification Test (AUDIT-K). DRD4 exon III 48 base pair variable number of tandem repeats (VNTR) was genotyped by PCR. Results No significant association was found between DRD4 polymorphism and TCI temperament dimension (novelty seeking, harm avoidance, reward dependence, and persistence) as well as alcohol drinking behavior scales. However, novelty seeking was significantly associated with alcohol drinking behavior. The higher level of novelty seeking was associated with the higher severity index of drinking (B = -0.225, p < 0.001) and problematic alcohol use on the CAGE and AUDIT-K [Odds Ratio (OR) = 1.111, 95% Confidence Interval (CI) 1.021-1.209, p = 0.015, OR = 1.087, 95% CI 1.009-1.170, p = 0.028]. Conclusion In our study, while there is no significant association of DRD4 polymorphism with temperament and alcohol drinking behavior, novelty seeking affects problematic alcohol use. Results suggest that novelty seeking may play an important role in problematic alcohol use in young Korean adults.

• Journal of Trauma and Injury
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• v.22 no.1
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• pp.65-70
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• 2009

Purpose: Many studies have addressed a psychiatric analysis of self-injury patients who have self-injurious behavior and who have attempted suicide. Few studies on the injury characteristics of self-injury related trauma patients have been conducted. We analyzed the injury characteristics of self-injury patients. Methods: A retrospective review of the medical records extracted from the injury surveillance system of Wonju Christian Hospital for the period from August 2006 to February 2008 was conducted. Of the 121 cases extracted, 103 were included in this study. We analyzed the sex ratio, age group, place of injury, injury mechanism, location of injury, management results, injury severity, and relation with drinking. Results: One hundred three cases were included (sex ratio: 1.06), and the mean age was $33.9{\pm}14.2$ years old. Fifty-six patients (54.4%) were discharged from the emergency department (ED) on the day of injury after primary care, and 9 patients (8.7%) were discharged, because they refused treatment. Seven patients (6.8%) died. Of these, 4 patients (3.9%) died after attempted cardio-pulmonary resuscitation in the ED, 1 patient (1%) was dead on arrival, and 2 patients (1.9%) died after admission. Sixteen patients (15.5%) were admitted to the hospital, including 2 patients (1.9%) needing emergency surgery. Sixteen patients (15.5%) were transferred to other hospitals. Sixty-one cases (59.2%) involved drinking, and 31 (30.1%) did not; for 11 cases (10.7%), the involvement of drinking was unknown. The mean revised trauma score (RTS) was $11.26{\pm}2.52$, and 88 cases (85.4%) hat a RTS of 12. The mean injury severity score (ISS) was $5.80{\pm}14.56$, and 9 (8.7%) severely injured patients had scores of more than 15. Conclusion: Most self-injuries were mild traumas related to drinking and occurred at a young age. Most cases were not so severe, and the patients were discharged from the ED, but some patients needed hospitalization. Other patients had injuries so severe that they died.

• Korean Journal of Health Education and Promotion
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• v.34 no.1
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• pp.1-12
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• 2017

Objectives: The aim of this study was to verify relationships between light- and heavy alcohol drinking and health-risk behaviors such as smoking, inappropriate weight control, physical inactivity, and sexual activity among adolescents. Methods: The data of 68,043 adolescents in middle- and high school collected from the Korea Youth Risk Behavior Web-based Survey in 2015 were analyzed. For statistical analysis, logistic regression model was used. Results: The rate of heavy alcohol drinking increased with increasing age up to 21.5% among boys and 13.9% among girls. Among boys, heavy alcohol drinkers were at a higher risk of smoking (adjusted odds ratios [OR]=3.3, 95% confidence interval [CI]=2.8-3.8), inappropriate weight control (OR=1.7; 95% CI=1.4-2.1), having sexual intercourse (OR=3.6; 95% CI=3.0-4.2) than light drinkers. Multiple health-risk behaviors of smoking, inappropriate weight control and sexual intercourse also increased in accordance with the severity of drinking alcohol beverage compared to non-drinker. Physical inactivity was decreased among heavy drinkers compared to light drinkers (OR=0.8; 95% CI=0.7-0.9 for inactivity of moderate exercise). Similar results were observed among girls. Conclusions: Alcohol drinking especially heavy alcohol drinking among adolescents is related to other risky behaviors including smoking, inappropriate weight control, and sexual activity. To prevent health problems in adolescents, it is necessary to adopt a combined approach regarding heavy drinking and health-risk behaviors.

• Journal of Korean Academy of Fundamentals of Nursing
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• v.8 no.3
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• pp.302-313
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• 2001

Purpose: To identify characteristics of chronic fatigue, difference between the duration of fatigue and characteristics of chronic fatigue, and association between chronic fatigue and related factors in adults. Method: The subjects for this study were 180 adults who had experienced fatigue for over one month The measurement tools were the Revised Fatigue Scale by Chalder et al. (1993), the Visual Analogue Scale-energy developed by Lee et al. (1991), the BEPSI (Brief Encounter Psychosocial Instrument) by Frank & Zyzanski (1988), Zung's self rating depression scale (1965) and life style items including exercise sleep, drinking smoking and diet as developed by the researchers. Results : Those who complained of fatigue over six months experienced higher disturbances in their daily life compared to those who had suffered from fatigue less than six months. There were a significant correlation between severity of fatigue and depression (r=.46, p<.001), stress (r=.41, p<.001), and sleep (r=.20, p<.01) Statistically significant relationships were found between severity of fatigue and amount of exercise per week (F=3.79. p<.05) disturbed sleep (t=-2.66, p<.01), number of times awakened during the night (F=3.48, p<.05) types of drinking (F=2.65, p<.05), and diet regularity (F=5.83, p<.01). The construction of a multiple regression model revealed an adjusted $R^2$ of .27 with the depression score serving the major predictor variables for severity of fatigue. Men and people in the younger age group were more energetic than women and those in other age groups. Also married people experienced more fatigue than people who were single. divorced or separated. Conclusion: In nursing interventions for fatigue, medical personnel should consider sociodemographic characteristics of the clients, ways to reduce of stress and counter disturbances in daily life and develop strategies for a health promoting life style.