• Title/Summary/Keyword: Set value test

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Improvement of the Result Related to Tumor Marker Test Through the OCS QC Program (OCS QC 프로그램을 통한 건진 센터 종양검사의 결과보고 개선)

  • Back, Song-Ran;Kim, Sung-Ho;Yoo, So-Yeon;Kim, Nyun-Ok;Moon, Hyoung-Ho;Yoo, Seon-Hee;Cho, Shee-Man
    • The Korean Journal of Nuclear Medicine Technology
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    • v.13 no.3
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    • pp.185-188
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    • 2009
  • Purpose: Standard of retests were discrepant and inconsistent due to inaccuracy and lack of standardization within normal range limit of tumor marker test. To enhance the standardization of retests set standard value below normal range and the Order Communication System Quality Control (OCS QC) program was put in place. This program enables managing the results within lower limit of normal range which were used for tumor marker test in Health Center. Materials and Methods: At present the tumor marker study for AFP, CEA, CA19-9, CA125, and PSA included outpatients in Asan Medical Center from February to March, 2009. The standard value was obtained by using the percentage of CV of Inter Assay according to the normal range of each tumor test. The results were confirmed by using the OCS QC program via formatted assessment of screening test such as test items, standard value and medical department. The number of out-of-range results within plus and minus 30 percents regarding the five primary items of tumor marker test was assessed. The next step was to obtain the number of AFP, CEA, and CA125 according to the ratio of comparison between prior and post test result, 60%, 50%, and 40% within normal range, respectively. In addition, set standard value below normal range. Results: The first screening test with percentage of sample number was resulted between 30%-40% and the second one was AFP 26.1%, CEA 18.9%, CA19-9 17.3%, CA125 18.7%, and PSA 21.0% obtained screening percentage of average 20 percents. The limited value of retest was AFP less than 5.0 and more than 10.0, CEA less than 1.0 and more than 3.0, CA19-9 less than 10.0 and more than 30.0, and PSA less than 1.0 and more than 2.0 to set and the number of retest was obtained by applying to the limited value of retest to screening percentage of average 20 percents For two months, the number of retest was AFP 0, CEA 15, CA19-9 3, CA125 2, and PSA 5. Conclusions: Through using the OCS QC program in establishing the standard of retest systemically, there appeared to be reduced discrepancy among the examiners and to be expected improvement in relation to the error of results.

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Effects of the Water Reducing Agent on the Concrete (減水劑가 콘크리트에 미치는 影響)

  • Kim, Jong-Cheon;Doh, Duk-Hyun
    • Magazine of the Korean Society of Agricultural Engineers
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    • v.24 no.2
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    • pp.67-75
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    • 1982
  • A study on the effect of water reducing agent on the various characteristics of concrete has been conducted. The experimental results of the study are summarized as follows. 1. Slump test for the concrete added water reducing setretarding agent in proper quantity have been conducted. According to the test results, the decreasing rate of slump value become bigger than plain concrete with increase of the unit weight of cement and elapse of time 2. In case the proper quantity content of maximum compressive strength in Fig. 5 of water reducing set retarding agent is added, unit weight of water is decreased about 15% or so as compared with plain concrete. with the increase of water reducing set accelerating agent content unit weight of water is decreased much more, And other hand, amount of air entraining shows the increasing tendency with the increase of water reducing agent content. 3. The adding rate of water reducing agent which produce maximum strength shows that WR-CH and WR-SA which is water reducing set-starding agent is 0.2% and WR-CO is 0.5% and that WS-PO which is water reducing set accelerating agent is 0.5 4. compressive strength jof the concrete made of sulfate resistant cement shows less than the strength of normal portland cement at initial strength but the strength of both cement shows almost same at curing age of 28 days. 5. when proper quantity of water reducing set retarding agent is used, boned strength is increased about 15% at curing age of 28days. 6. According to the result of durability test, dynamic young's mudulus of elasticity at plain concrete is decreased about 50% as compared with initial step at 300 cycle of freezing and thawing after curing age of days. on the contarary the concrete used water reducing agent is decreased less than 7%.

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Genetic Function Approximation and Bayesian Models for the Discovery of Future HDAC8 Inhibitors

  • Thangapandian, Sundarapandian;John, Shalini;Lee, Keun-Woo
    • Interdisciplinary Bio Central
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    • v.3 no.4
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    • pp.15.1-15.11
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    • 2011
  • Background: Histone deacetylase (HDAC) 8 is one of its family members catalyzes the removal of acetyl groups from N-terminal lysine residues of histone proteins thereby restricts transcription factors from being expressed. Inhibition of HDAC8 has become an emerging and effective anti-cancer therapy for various cancers. Application computational methodologies may result in identifying the key components that can be used in developing future potent HDAC8 inhibitors. Results: Facilitating the discovery of novel and potential chemical scaffolds as starting points in the future HDAC8 inhibitor design, quantitative structure-activity relationship models were generated with 30 training set compounds using genetic function approximation (GFA) and Bayesian algorithms. Six GFA models were selected based on the significant statistical parameters calculated during model development. A Bayesian model using fingerprints was developed with a receiver operating characteristic curve cross-validation value of 0.902. An external test set of 54 diverse compounds was used in validating the models. Conclusions: Finally two out of six models based on their predictive ability over the test set compounds were selected as final GFA models. The Bayesian model has displayed a high classifying ability with the same test set compounds and the positively and negatively contributing molecular fingerprints were also unveiled by the model. The effectively contributing physicochemical properties and molecular fingerprints from a set of known HDAC8 inhibitors were identified and can be used in designing future HDAC8 inhibitors.

Characteristics Evaluation and Useful Life Prediction of Rubber Spring for Railway Vehicle (전동차용 방진고무스프링 특성평가 및 사용수명 예측)

  • Woo, Chang-Su;Park, Dong-Chul
    • Proceedings of the KSR Conference
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    • 2006.11b
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    • pp.104-111
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    • 2006
  • The non-linear properties of rubber material which are described as strain energy function are important parameter to design and evaluate of rubber spring. These are determined by material tests which are uni-axial tension and bi-axial tension. The computer simulation using the nonlinear element analysis program executed to predict and evaluate the load capacity and stiffness for chevron spring. In order to investigate the heat-aging effects on the rubber material properties, the acceleration test were carried out. Compression set results changes as the threshold are used for assessment of the useful life and time to threshold value were plotted against reciprocal of absolute temperature to give the Arrhenius plot. By using the compression set test, several useful life prediction for rubber material were proposed.

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On the Retesting Methodology and Reusing Test Cases for Software Maintenance (소프트웨어 유지보수를 위한 리테스팅 방법론과 테스트 케이스 재사용에 관하여)

  • Hwang, Seon-Myeong;Jin, Yeong-Taek
    • The Transactions of the Korea Information Processing Society
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    • v.2 no.1
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    • pp.45-54
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    • 1995
  • Retest arises when attemptint to validate code modifications. This paper proposes a retest methodology which explicitly defines the amount of retesting to be performed for any given code change. In order to minimize the objective function, we use the set/use matrix through analysis of data dependence as well as the connectivity, reachability, and test case/reference matrix through program control flow analysis. The value of objective function will give the minimum number of test cases necessary to assure the proposed methodology, we develope the retesting tool for generating mininum test cases based on the function.

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Consumption Value, Consumer Innovativeness and New Product Adoption: Empirical Evidence from Vietnam

  • DU, Chung Thi;NGO, Thu Thi;TRAN, Thi Van;NGUYEN, Ngoc Bich Tram
    • The Journal of Asian Finance, Economics and Business
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    • v.8 no.3
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    • pp.1275-1286
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    • 2021
  • The purpose of this study is to employ the theory of consumption value and consumers' innovative personality characteristics to explain the adoption of new personal electronics devices in Vietnamese market. This study adapts a quantitative survey-based approach to test hypotheses about relationship between consumption value, product specific innovativeness and new product adoption. The study uses a quantitative data set of 915 consumers who owned one mobile electronic device at least in Ho Chi Minh city, one of the biggest cities of Vietnam. The data was collected through personal interview and convenient sampling method. The conceptual model was tested using PLS structural equation model. The findings of this study suggest that both consumption value and product specific innovativeness influence the adoption of new electronic products. The results also reveal that product specific innovativeness mediates the relationship between consumption value and new product adoption. The study further identified that consumption value was taken as a second-order multidimensions construct with five components, namely functional value, epistemic value, economic value, social value and emotional value. As a result, the research suggests some implications to enhance marketers' capabilities to develop strategies for launching new hi-tech products in an emerging market as Vietnam.

Usefulness of the High B-value DWI in Brain Tumors (뇌종양 확산강조영상에서 High B-value의 유용성 평가)

  • Kim, Jin-tae;Byun, Jae-Hu;Park, Yong-Seong;Lee, Rae-Gon;Hwang, Seon-Kwang
    • Korean Journal of Digital Imaging in Medicine
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    • v.17 no.1
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    • pp.33-41
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    • 2015
  • This study attempts to examine the clinical usefulness of High b-value DWI (diffusion weighted imaging) for brain tumors with an edema. Subjects were seven patients selected from 65 patients who received an MRI scan for suspected encephalopathy and confirmed diagnosis at our hospital from February to July 2015 (male: 7, average age : 66 years old). As test equipment, 3.0T MR System (ACHIEVA Release, Philips, Best, The Netherlands) and 8Channel SENSE Head Coill were used. DWI checks on the use of the variable TR 5460ms, TE 132ms, Slice Thickness 4mm, gap 1mm, Slice number 29 is, 3D T1WI is TR 8.4ms, TE 3.9ms, matrix size $240{\times}240$, Slice can set 180 piecesIt was. b value of 0, 1,000, 2,000 s/mm2 with DWI acquisition and 3D T1WI enhancement five minutes after the Slice Thickness 3mm, gap 0mm to reconstruct the upper face axis (MPR TRA CE) was. As for the experiment, in b-value 1,000 and 2,000 images, SNR and the lesion at the lesion site and CNR in the normal site opposite to the lesion are measured. WW(window width) and WL(window level) are made equal in MRICro software, and the volume of the lesion is measured from each of b-value and MPR TRA CE image. Using SPSS ver. 1.8.0.0 Mann Whitney-test was analyzed for SNR and CNR, while Kruskal-Wallis test was analyzed for volume.

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Improvements of Multi-features Extraction for EMG for Estimating Wrist Movements (근전도 신호기반 손목 움직임의 추정을 위한 다중 특징점 추출 기법 알고리즘)

  • Kim, Seo-Jun;Jeong, Eui-Chul;Lee, Sang-Min;Song, Young-Rok
    • The Transactions of The Korean Institute of Electrical Engineers
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    • v.61 no.5
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    • pp.757-762
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    • 2012
  • In this paper, the multi feature extraction algorithm for estimation of wrist movements based on Electromyogram(EMG) is proposed. For the extraction of precise features from the EMG signals, the difference absolute mean value(DAMV), the mean absolute value(MAV), the root mean square(RMS) and the difference absolute standard deviation value(DASDV) to consider amplitude characteristic of EMG signals are used. We figure out a more accurate feature-set by combination of two features out of these, because of multi feature extraction algorithm is more precise than single feature method. Also, for the motion classification based on EMG, the linear discriminant analysis(LDA), the quadratic discriminant analysis(QDA) and k-nearest neighbor(k-NN) are used. We implemented a test targeting twenty adult male to identify the accuracy of EMG pattern classification of wrist movements such as up, down, right, left and rest. As a result of our study, the LDA, QDA and k-NN classification method using feature-set with MAV and DASDV showed respectively 87.59%, 89.06%, 91.75% accuracy.

A Study of the PSS Parameter setting for 5Kw Motor-Generator Set (5KW 축약 발전기를 대상으로한 PSS 파라미터 정정 연구)

  • Lim, Ik-Hyun;Ryu, Ho-Seon;Kim, Kyung-Chul;Kim, Sae-Yong
    • Proceedings of the KIEE Conference
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    • 1998.07c
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    • pp.958-960
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    • 1998
  • This paper presents an application of power system stabilizer for a 5Kw Motor-Generator Set. The power system which was consisted of 5Kw Motor-Generator Set. Excitation system, Governor system and PSS was used for the performance test. The method by changing the PSS gain to allocate properly pole-zero positions was used for setting PSS parameter value. The result of the experiment was satisfactory.

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Result Analysis according to Population Distribution Trends when Reagents are Changed (시약 변경 시 모집단 분포 추이에 따른 결과 분석)

  • Hye-Mi Park;Soo-Yeon Lim;Sun-Hee Yoo;Sun-Ho Lee
    • The Korean Journal of Nuclear Medicine Technology
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    • v.27 no.1
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    • pp.55-61
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    • 2023
  • Purpose In this study, the monthly population distribution was calculated for statistical verification of 10 tests (CA19-9, CA15-3, testosterone, PTH, calcitonin, AFP, CEA, CA72-4, PSA, estradiol) with changed reagents, and the trend of change By comparing and analyzing the results, we want to verify the accuracy of the results and improve the reliability of the test. Materials and Methods From June 2021 to February 2023, for the 10 items in which the reagent was changed, the monthly percentage and standard deviation index before and after the reagent change were compared, respectively. At this time, the reference value was arbitrarily set for the comparison group in consideration of the reference value of the test item, and the groups were subdivided and compared, and the standard deviation index allowed range was -2.0 or more and 2.0 or less. Results For CA19-9, CA15-3, AFP, CEA, and calcitonin 5 test items, the change in monthly ratio in all test sections before and after the reagent change was kept constant. On the other hand, for CA72-4, PSA, testosterone, PTH, and estradiol items, the standard deviation index exceeded the acceptable standard after changing the reagent. CA72-4 test items showed an increasing trend in standard deviation index in the test section exceeding the reference value. In the case of the PSA test item, the maintenance ratio of 0.04 ng/mL was significantly decreased after changing the reagent. The testosterone test item had a standard deviation index of -2.5 in the test section exceeding 10.1 ng/mL after changing the reagent, and the standard deviation index of the PTH test item was out of the acceptable range in all test sections. It was confirmed that the estradiol test item showed an overall increase in the result value. Conclusion Through this study, the continuity and accuracy of the test results could be verified. It is considered that the stability of the test can be secured by analyzing the factors affecting the test result and solving the cause for the test item whose standard deviation index is out of the acceptable standard.

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